Temporal vulnerability of fetal cerebellar purkinje cells to chronic binge alcohol exposure: Ovine model

Alcoholism: Clinical and Experimental Research

Volumn 31, Issue 10, 2007, Pages 1738-1745

  Ramadoss, Jayanth ^a   Lunde, Emilie R ^a   Chen, Wei Jung A ^b   West, James R ^b   Cudd, Timothy A ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

Author keywords

Alcohol; Cerebellum; Fetal Alcohol Spectrum Disorder; Purkinje Cell; Temporal Vulnerability

Indexed keywords

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL DAMAGE; CELL DENSITY; CONTROLLED STUDY; FETUS GROWTH; FIRST TRIMESTER PREGNANCY; LONG TERM EXPOSURE; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; RISK ASSESSMENT; SHEEP; THIRD TRIMESTER PREGNANCY;

ALCOHOL DRINKING; ALCOHOLISM; ANIMALS; CELL COUNT; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CEREBELLUM; DISEASE MODELS, ANIMAL; ETHANOL; FEMALE; MATERNAL-FETAL EXCHANGE; PREGNANCY; PURKINJE CELLS; SHEEP;

ANIMALIA; OVIS; OVIS ARIES; RATTUS;

EID: 34548599907     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2007.00477.x     Document Type: Article

References (53)

1. Archibald SL, Fennema-Notestine C, Gamst A, Riley EP, Mattson SN, Jernigan TL (2001) Brain dysmorphology in individuals with severe prenatal alcohol exposure. Dev Med Child Neurol 43 : 148 154.
2. Autti-Ramo I, Autti T, Korkman M, Kettunen S, Salonen O, Valanne L (2002) MRI findings in children with school problems who had been exposed prenatally to alcohol. Dev Med Child Neurol 44 : 98 106.
3. Bonthius DJ, Bonthius NE, Napper RM, West JR (1992) Early postnatal alcohol exposure acutely and permanently reduces the number of granule cells and mitral cells in the rat olfactory bulb: a stereological study. J Comp Neurol 324 : 557 566.
4. Bonthius DJ, West JR (1990) Alcohol-induced neuronal loss in developing rats: increased brain damage with binge exposure. Alcohol Clin Exp Res 14 : 107 118.
5. Bonthius DJ, West JR (1991) Permanent neuronal deficits in rats exposed to alcohol during the brain growth spurt. Teratology 44 : 147 163.
6. Caetano R, Ramisetty-Mikler S, Floyd LR, McGrath C (2006) The epidemiology of drinking among women of child-bearing age. Alcohol Clin Exp Res 30 : 1023 1030.
7. CDC (2004) Alcohol consumption among women who are pregnant or who might become pregnant - United States, 2002. MMWR 53 : 1178 1181.
8. Chen WJ, Maier SE, Parnell SE, West JR (2003) Alcohol and the developing brain: neuroanatomical studies. Alcohol Res Health 27 : 174 180.
9. Church MW, Gerkin KP (1988) Hearing disorders in children with fetal alcohol syndrome: findings from case reports. Pediatrics 82 : 147 154.
10. Clarren SK (1977) Central nervous system malformations in two offspring of alcoholic women. Birth Defects Orig Artic Ser 13 : 151 153.
11. Clarren SK, Alvord EC Jr., Sumi SM, Streissguth AP, Smith DW (1978) Brain malformations related to prenatal exposure to ethanol. J Pediatr 92 : 64 67.
12. Coulter CL, Leech RW, Schaefer GB, Scheithauer BW, Brumback RA (1993) Midline cerebral dysgenesis, dysfunction of the hypothalamic-pituitary axis, and fetal alcohol effects. Arch Neurol 50 : 771 775.
13. Cragg B, Phillips S (1985) Natural loss of Purkinje cells during development and increased loss with alcohol. Brain Res 325 : 151 160.
14. Cudd TA (2005) Animal model systems for the study of alcohol teratology. Exp Biol Med (Maywood) 230 : 389 393.
15. Cudd TA, Chen And WJ, West JR (2001a) Fetal and maternal sheep hypothalamus pituitary adrenal axis responses to chronic binge ethanol exposure during the third trimester equivalent. Alcohol Clin Exp Res 25 : 1065 1071.
16. Cudd TA, Chen WJ, Parnell SE, West JR (2001b) Third trimester binge ethanol exposure results in fetal hypercapnea and acidemia but not hypoxemia in pregnant sheep. Alcohol Clin Exp Res 25 : 269 276.
17. de Lahunta A (1983) Cerebellum in Veterinary Neuroanatomy and Clinical Neurology. WB Saunders company, Philadelphia, PA.
18. Dobbing J, Sands J (1973) Quantitative growth and development of human brain. Arch Dis Child 48 : 757 767.
19. Dobbing J, Sands J (1979) Comparative aspects of the brain growth spurt. Early Hum Dev 3 : 79 83.
20. Ebrahim SH, Diekman ST, Floyd RL, Decoufle P (1999) Comparison of binge drinking among pregnant and nonpregnant women, United States, 1991-1995. Am J Obstet Gynecol 180 : 1 7.
21. Gladstone J, Nulman I, Koren G (1996) Reproductive risks of binge drinking during pregnancy. Reprod Toxicol 10 : 3 13.
22. Goodlett CR, Eilers AT (1997) Alcohol-induced Purkinje cell loss with a single binge exposure in neonatal rats: a stereological study of temporal windows of vulnerability. Alcohol Clin Exp Res 21 : 738 744.
23. Goodlett CR, Pearlman AD, Lundahl KR (1998) Binge neonatal alcohol intubations induce dose-dependent loss of Purkinje cells. Neurotoxicol Teratol 20 : 285 292.
24. Hamre KM, West JR (1993) The effects of the timing of ethanol exposure during the brain growth spurt on the number of cerebellar Purkinje and granule cell nuclear profiles. Alcohol Clin Exp Res 17 : 610 622.
25. Hannigan JH, Martier SS, Chugani HT, Sowell RJ (1995) Brain metabolism in children with fetal alcohol syndrome (FAS): a positron emission tomography study. Alcohol Clin Exp Res 19 : 53A.
26. Institute of Medicine (1996) Fetal Alcohol Syndrome. Diagnosis, Epidemiology, Prevention, and Treatment. National Academy press, Washington, DC.
27. Jacobson M (1991) Histogenesis and Morphogenesis of Cortical Structures in Developmental Neurobiology. Plenum Press, New York.
28. Livy DJ, Miller EK, Maier SE, West JR (2003) Fetal alcohol exposure and temporal vulnerability: effects of binge-like alcohol exposure on the developing rat hippocampus. Neurotoxicol Teratol 25 : 447 458.
29. Maier SE, Chen WJ, Miller JA, West JR (1997) Fetal alcohol exposure and temporal vulnerability regional differences in alcohol-induced microencephaly as a function of the timing of binge-like alcohol exposure during rat brain development. Alcohol Clin Exp Res 21 : 1418 1428.
30. Maier SE, Miller JA, Blackwell JM, West JR (1999) Fetal alcohol exposure and temporal vulnerability: regional differences in cell loss as a function of the timing of binge-like alcohol exposure during brain development. Alcohol Clin Exp Res 23 : 726 734.
31. Maier SE, West JR (2001a) Drinking patterns and alcohol-related birth defects. Alcohol Res Health 25 : 168 174.
32. Maier SE, West JR (2001b) Regional differences in cell loss associated with binge-like alcohol exposure during the first two trimesters equivalent in the rat. Alcohol 23 : 49 57.
33. Maier SE, West JR (2003) Alcohol and nutritional control treatments during neurogenesis in rat brain reduce total neuron number in locus coeruleus, but not in cerebellum or inferior olive. Alcohol 30 : 67 74.
34. Marcussen BL, Goodlett CR, Mahoney JC, West JR (1994) Developing rat Purkinje cells are more vulnerable to alcohol-induced depletion during differentiation than during neurogenesis. Alcohol 11 : 147 156.
35. Maternal and Child Health (MCH) Data Report (2003) Alcohol Use during Pregnancy. Washington State Department of Health, Washington, DC.
36. NIAAA (2000) Underlying mechanisms of alcohol-induced damage to the fetus, in Tenth Special Report to the U.S. Congress on Alcohol and Health, pp 285 322. U.S. Department of Health and Human Services, Bethesda, MD.
37. Pauli J, Wilce P, Bedi KS (1995) Acute exposure to alcohol during early postnatal life causes a deficit in the total number of cerebellar Purkinje cells in the rat. J Comp Neurol 360 : 506 512.
38. Peiffer J, Majewski F, Fischbach H, Bierich JR, Volk B (1979) Alcohol embryo- and fetopathy. Neuropathology of 3 children and 3 fetuses. J Neurol Sci 41 : 125 137.
39. Penton Z (1985) Headspace measurement of ethanol in blood gas chromatography with a modified autosampler. Clin Chem 31 : 439 441.
40. Ramadoss J, Hogan HA, Given JC, West JR, Cudd TA (2006a) Binge alcohol exposure during all three trimesters alters bone strength and growth in fetal sheep. Alcohol 38 : 185 192.
41. Ramadoss J, Lunde ER, Pina K.B, Chen WJ, Cudd TA (2006b) Role of hypercapnea and acidemia in alcohol mediated fetal cerebellar injury. Alcohol Clin Exp Res 30 : 229A.
42. Ramadoss J, Lunde ER, Pina KB, Chen WJ, Cudd TA (2007) All three trimester binge alcohol exposure causes fetal cerebellar purkinje cell loss in the presence of maternal hypercapnea, acidemia and normoxemia: ovine model. Alcohol Clin Exp Res 31 : 1252 1258.
43. Rees S, Harding R (1988) The effects of intrauterine growth retardation on the development of the Purkinje cell dendritic tree in the cerebellar cortex of fetal sheep: a note on the ontogeny of the Purkinje cell. Int J Dev Neurosci 6 : 461 469.
44. Reynolds JD, Penning DH, Dexter F, Atkins B, Hrdy J, Poduska D, Brien JF (1996) Ethanol increases uterine blood flow and fetal arterial blood oxygen tension in the near-term pregnant ewe. Alcohol 13 : 251 256.
45. Riley EP, McGee CL (2005) Fetal alcohol spectrum disorders: an overview with emphasis on changes in brain and behavior. Exp Biol Med (Maywood) 230 : 357 365.
46. Roebuck TM, Mattson SN, Riley EP (1998) A review of the neuroanatomical findings in children with fetal alcohol syndrome or prenatal exposure to alcohol. Alcohol Clin Exp Res 22 : 339 344.
47. Sokol RJ, Delaney-Black V, Nordstrom B (2003) Fetal alcohol spectrum disorder. JAMA 290 : 2996 2999.
48. Sowell ER, Jernigan TL, Mattson SN, Riley EP, Sobel DF, Jones KL (1996) Abnormal development of the cerebellar vermis in children prenatally exposed to alcohol: size reduction in lobules I-V. Alcohol Clin Exp Res 20 : 31 34.
49. Swayze VW II., Johnson VP, Hanson JW, Piven J, Sato Y, Giedd JN, Mosnik D, Andreasen NC (1997) Magnetic resonance imaging of brain anomalies in fetal alcohol syndrome. Pediatrics 99 : 232 240.
50. Urso T, Gavaler JS, Van Thiel DH (1981) Blood ethanol levels in sober alcohol users seen in an emergency room. Life Sci 28 : 1053 1056.
51. West JR, Parnell SE, Chen WJ, Cudd TA (2001) Alcohol-mediated Purkinje cell loss in the absence of hypoxemia during the third trimester in an ovine model system. Alcohol Clin Exp Res 25 : 1051 1057.
52. West JR, Ward GR (1992) Effects of alcohol on the developing brain, in Encephalopathies of Infancy and Childhood (Miller G, Ramer JC eds pp 311 318. Raven press, New York.
53. Wisniewski K, Dambska M, Sher JH, Qazi Q (1983) A clinical neuropathological study of the fetal alcohol syndrome. Neuropediatrics 14 : 197 201.