Abnormal development of the cerebellar vermis in children prenatally exposed to alcohol: Size reduction in lobules I-V

Alcoholism: Clinical and Experimental Research

Volumn 20, Issue 1, 1996, Pages 31-34

  Sowell, Elizabeth R ^a   Jernigan, Terry L ^b,c   Mattson, Sarah N ^a   Riley, Edward P ^a   Sobel, David F ^b   Jones, Kenneth Lyons ^b  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cerebellum; Fetal Alcohol Syndrome; Magnetic Resonance Imaging; Prenatal Alcohol Exposure; Vermis

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BRAIN DEVELOPMENT; CELL LOSS; CEREBELLUM VERMIS; CHILD; CLINICAL ARTICLE; DEVELOPMENTAL DISORDER; FEMALE; FETAL ALCOHOL SYNDROME; GRANULE CELL; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PURKINJE CELL; SCHOOL CHILD;

ADOLESCENT; ADULT; CELL DEATH; CEREBELLUM; CHILD; FEMALE; FETAL ALCOHOL SYNDROME; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; PURKINJE CELLS;

ANIMALIA;

EID: 0029865053     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1530-0277.1996.tb01039.x     Document Type: Article

References (13)

1. Jones KL, Smith DW: The fetal alcohol syndrome. Teratology 12:1-10, 1975
2. Clarren SK: Neuropathology in fetal alcohol syndrome, in West JR (ed): Alcohol and Brain Development. New York, Oxford University Press, 1986
3. Mattson SN, Riley EP, Jernigan TL, Garcia A, Kaneko WM, Ehlers CL, Jones KL: A decrease in the size of the basal ganglia following prenatal alcohol exposure: A preliminary report. Neurotoxicol Teratol 16:283-289, 1994
4. Mattson SN, Riley EP, Jernigan TL, Ehlers CL, Delis DC, Jones KL, Stern C, Johnson KA, Hesselink JR, Bellugi U: Fetal alcohol syndrome: A case report of neuropsychological, MRI, and EEG assessment of two children. Alcohol Clin Exp Res 16:1001-1003, 1992
5. Samson HH, Diaz J: Altered development of brain by neonatal ethanol exposure: Zinc levels during and after exposure. Alcohol Clin Exp Res 5:563-569, 1981
6. Jacobson S, Rich J, Tovsky NJ: Delayed myelination and lamination in the cerebral cortex of the albino rat as a result of the fetal alcohol syndrome, in Galanter M (ed): Currents in Alcoholism, vol 5. New York, Grune & Stratton, 1979
7. West JR, Hodges CA, Black AC: Prenatal exposure to ethanol alters the organization of hippocampal mossy fibers in rats. Science 211: 957-959, 1981
8. Goodlett CR, Marcussen BL, West JR: A single day of alcohol exposure during the brain growth spurt induces brain weight restriction and cerebellar Purkinje cell loss. Alcohol 7:107-114, 1990
9. Jones KL; Smith DW, Ulleland CN, Streissguth AP: Pattern of malformation in offspring of chronic alcoholic mothers. Lancet 1:1267-1271, 1973
10. Courchesne E, Hesselink JR, Jernigan TL, Yeung-Courchesne R: Abnormal neuroanatomy in a nonretarded person with autism: Unusual findings with magnetic resonance imaging. Arch Neurol 44:335-341, 1987
11. Courchesne E, Yeung-Courchesne R, Press GA, Hesselink JR, Jernigan TL: Hypoplasia of cerebellar vermal lobules VI and VII in autism. N Engl J Med 318:1349-1354, 1988
12. West JR, Goodett CR, Bonthius DJ, Hamre KM, Marcussen BL: Cell population depletion associated with fetal alcohol brain damage: Mechanisms of BAC-dependent cell loss. Alcohol Clin Exp Res 14:813-818, 1990
13. Jernigan TL, Bellugi U: Anomalous brain morphology on magnetic resonance images in Williams syndrome and Down syndrome. Arch Neurol 47:529-533, 1990