WASP localizes to the membrane skeleton of platelets

British Journal of Haematology

Volumn 139, Issue 1, 2007, Pages 98-105

  Lutskiy, Maxim I ^b   Shcherbina, Anna ^c   Bachli, Eric T ^b   Cooley, Jessica ^b   Remold O'Donnell, Eileen ^a,b  

^a CENTER FOR BLOOD RESEARCH   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Federal Clinical Research Center for Paediatric Haematology Oncology and Immunology   (Russian Federation)

Author keywords

Integrin outside in signalling; Membrane skeleton; Platelets; WASP; Wiskott Aldrich syndrome

Indexed keywords

CALPAIN; CYSTEINE PROTEINASE; DETERGENT; INTEGRIN; SCAFFOLD PROTEIN; THROMBIN; WISKOTT ALDRICH SYNDROME PROTEIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOARCHITECTURE; LIPID BILAYER; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEFICIENCY; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; PROTEIN STRUCTURE; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION; WISKOTT ALDRICH SYNDROME;

BLOOD PLATELETS; BLOTTING, WESTERN; CALPAIN; CELL MEMBRANE; CELLS, CULTURED; HUMANS; PHOSPHORYLATION; PLATELET ACTIVATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PLATELET MEMBRANE GLYCOPROTEINS; THROMBIN; WISKOTT-ALDRICH SYNDROME; WISKOTT-ALDRICH SYNDROME PROTEIN;

EID: 34548593650     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2007.06745.x     Document Type: Article

References (35)

1. Azim, A.C., Barkalow, K., Chou, J. Hartwig, J.H. (2000) Activation of the small GTPases, rac and cdc42, after ligation of the platelet PAR-1 receptor. Blood, 95, 959 964.
2. Bennett, V. Baines, A.J. (2001) Spectrin and ankyrin-based pathways: metazoan inventions for integrating cells into tissues. Physiological Reviews, 81, 1353 1392.
3. Bennett, J.S., Shattil, S.J., Power, J.W. Gartner, T.K. (1988) Interaction of fibrinogen with its platelet receptor. Differential effects of alpha and gamma chain fibrinogen peptides on the glycoprotein IIb-IIIa complex. Journal of Biological Chemistry, 263, 12948 12953.
4. Bertagnolli, M.E. Beckerle, M.C. (1993) Evidence for the selective association of a subpopulation of GPIIb-IIIa with the actin cytoskeletons of thrombin-activated platelets. Journal of Cell Biology, 121, 1329 1342.
5. Burns, S., Cory, G.O., Vainchenker, W. Thrasher, A.J. (2004) Mechanisms of WASp-mediated hematologic and immunologic disease. Blood, 104, 3454 3462.
6. Cory, G.O., Garg, R., Cramer, R. Ridley, A.J. (2002) Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein. Journal of Biological Chemistry, 277, 45115 45121.
7. Dash, D., Aepfelbacher, M. Siess, W. (1995) Integrin alpha IIb beta 3-mediated translocation of CDC42Hs to the cytoskeleton in stimulated human platelets. Journal of Biological Chemistry, 270, 17321 17326.
8. Delaunay, J. (2007) The molecular basis of hereditary red cell membrane disorders. Blood Reviews, 21, 1 20.
9. Falet, H., Hoffmeister, K.M., Neujahr, R. Hartwig, J.H. (2002) Normal Arp2/3 complex activation in platelets lacking WASp. Blood, 100, 2113 2122.
10. Fox, J.E. (1993) The platelet cytoskeleton. Thrombosis and Haemostasis, 70, 884 893.
11. Fox, J.E., Lipfert, L., Clark, E.A., Reynolds, C.C., Austin, C.D. Brugge, J.S. (1993) On the role the platelet membrane skeleton in mediating signal transduction. Association of GP IIb-IIIa, pp60c-src, pp62c-yes, and the p21ras GTPase-activating protein with the membrane skeleton. Journal of Biological Chemistry, 268, 25973 25984.
12. Fox, J.E., Shattil, S.J., Kinlough-Rathbone, R.L., Richardson, M., Packham, M.A. Sanan, D.A. (1996) The platelet cytoskeleton stabilizes the interaction between alphaIIbbeta3 and its ligand and induces selective movements of ligand-occupied integrin. Journal of Biological Chemistry, 271, 7004 7011.
13. Gemmell, C.H., Sefton, M.V. Yeo, E.L. (1993) Platelet-derived microparticle formation involves glycoprotein IIb-IIIa. Inhibition by RGDS and a Glanzmann's thrombasthenia defect. Journal of Biological Chemistry, 268, 14586 14589.
14. Gross, B.S., Wilde, J.I., Quek, L., Chapel, H., Nelson, D.L. Watson, S.P. (1999) Regulation and function of WASp in platelets by the collagen receptor, glycoprotein VI. Blood, 94, 4166 4176.
15. Hartwig, J.H. DeSisto, M. (1991) The cytoskeleton of the resting human blood platelet: structure of the membrane skeleton and its attachment to actin filaments. Journal of Cell Biology, 112, 407 425.
16. Higgs, H.N. Pollard, T.D. (2000) Activation by Cdc42 and PIP(2) of Wiskott-Aldrich syndrome protein (WASp) stimulates actin nucleation by Arp2/3 complex. Journal of Cell Biology, 150, 1311 1320.
17. Higgs, H.N., Blanchoin, L. Pollard, T.D. (1999) Influence C terminus of Wiskott-Aldrich syndrome protein (WASp) and the Arp2/3 complex on actin polymerization. Biochemistry, 38, 15212 15222.
18. Kim, A.S., Kakalis, L.T., Abdul-Manan, N., Liu, G.A. Rosen, M.K. (2000) Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein. Nature, 404, 151 158.
19. Loftus, J.C., Plow, E.F., Frelinger, III., A.L., D'Souza, S.E., Dixon, D., Lacy, J., Sorge, J. Ginsberg, M.H. (1987) Molecular cloning and chemical synthesis of a region of platelet glycoprotein IIb involved in adhesive function. Proceedings of the National Academy of Sciences of the United States of America, 84, 7114 7118.
20. Lutskiy, M.I., Rosen, F.S. Remold-O'Donnell, E. (2005) Genotype-proteotype linkage in the wiskott-Aldrich syndrome. Journal of Immunology, 175, 1329 1336.
21. Machesky, L.M. Insall, R.H. (1998) Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complex. Current Biology, 8, 1347 1356.
22. Mitchell, W.B., Li, J.H., Singh, F., Michelson, A.D., Bussel, J., Coller, B.S. French, D.L. (2003) Two novel mutations in the alpha IIb calcium-binding domains identify hydrophobic regions essential for alpha IIbbeta 3 biogenesis. Blood, 101, 2268 2276.
23. Ochs, H.D. Thrasher, A.J. (2006) The Wiskott-Aldrich syndrome. Journal of Allergy and Clinical Immunology, 117, 725 738 quiz 739.
24. Oda, A., Ochs, H.D., Druker, B.J., Ozaki, K., Watanabe, C., Handa, M., Miyakawa, Y. Ikeda, Y. (1998) Collagen induces tyrosine phosphorylation of Wiskott-Aldrich syndrome protein in human platelets. Blood, 92, 1852 1858.
25. Phillips, D.R., Jennings, L.K. Prasanna, H.R. (1980) Ca2+-mediated association of glycoprotein G (thrombinsensitive protein, thrombospondin) with human platelets. Journal of Biological Chemistry, 255, 11629 11632.
26. Remold-O'Donnell, E., Cooley, J., Shcherbina, A., Hagemann, T.L., Kwan, S.P., Kenney, D.M. Rosen, F.S. (1997) Variable expression of WASP in B cell lines of Wiskott-Aldrich syndrome patients. Journal of Immunology, 158, 4021 4025.
27. Rengan, R., Ochs, H.D., Sweet, L.I., Keil, M.L., Gunning, W.T., Lachant, N.A., Boxer, L.A. Omann, G.M. (2000) Actin cytoskeletal function is spared, but apoptosis is increased, in WAS patient hematopoietic cells. Blood, 95, 1283 1292.
28. Rohatgi, R., Ma, L., Miki, H., Lopez, M., Kirchhausen, T., Takenawa, T. Kirschner, M.W. (1999) The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly. Cell, 97, 221 231.
29. Shcherbina, A., Rosen, F.S. Remold-O'Donnell, E. (1999a) Pathological events in platelets of Wiskott-Aldrich syndrome patients. British Journal of Haematology, 106, 875 883.
30. Shcherbina, A., Rosen, F.S. Remold-O'Donnell, E. (1999b) WASP levels in platelets and lymphocytes of Wiskott-Aldrich syndrome patients correlate with cell dysfunction. Journal of Immunology, 163, 6314 6320.
31. Shcherbina, A., Miki, H., Kenney, D.M., Rosen, F.S., Takenawa, T. Remold-O'Donnell, E. (2001) WASP and N-WASP in human platelets differ in sensitivity to protease calpain. Blood, 98, 2988 2991.
32. Suetsugu, S., Hattori, M., Miki, H., Tezuka, T., Yamamoto, T., Mikoshiba, K. Takenawa, T. (2002) Sustained activation of N-WASP through phosphorylation is essential for neurite extension. Developmental Cell, 3, 645 658.
33. Sullivan, K.E., Mullen, C.A., Blaese, R.M. Winkelstein, J.A. (1994) A multiinstitutional survey of the Wiskott-Aldrich syndrome. Journal of Pediatrics, 125, 876 885.
34. Torres, E. Rosen, M.K. (2003) Contingent phosphorylation/ dephosphorylation provides a mechanism of molecular memory in WASP. Molecular Cell, 11, 1215 1227.
35. Yarar, D., D'Alessio, J.A., Jeng, R.L. Welch, M.D. (2002) Motility determinants in WASP family proteins. Molecular Biology of the Cell, 13, 4045 4059.