Synthesis of the A,B-ring-truncated OSW saponin analogs and their antitumor activities

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 20, 2007, Pages 5506-5509

  Peng, Wenjie ^a   Tang, Pingping ^a   Hu, Xiaoyi ^b   Liu, Jun O ^b   Yu, Biao ^a  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antitumor activity; Glycosides; OSW saponins; Synthesis; trans Hydrindane

Indexed keywords

ANTINEOPLASTIC AGENT; SAPONIN DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER; CONTROLLED STUDY; DRUG MECHANISM; DRUG SYNTHESIS; FEMALE; HELA CELL; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CHOLESTENONES; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; SAPONINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34548574624     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.08.060     Document Type: Article

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