Cytotoxicity of the novel spin trapping compound 5-ethoxycarbonyl-3,5-dimethyl-pyrroline N-oxide (3,5-EDPO) and its derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 20, 2007, Pages 5698-5703

  Rohr Udilova, Nataliya ^a,c   Stolze, Klaus ^b   Sagmeister, Sandra ^c   Parzefall, Wolfram ^c   Marian, Brigitte ^c   Nohl, Hans ^b   Schulte Hermann, Rolf ^c   Grasl Kraupp, Bettina ^c  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b UNIVERSITY OF VETERINARY MEDICINE   (Austria)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Cytotoxicity; ESR; Free radicals; Oxidative stress; Spin traps; Superoxide

Indexed keywords

3,5 DIMETHYL 5 (ISOPROPOXYCARBONYL) 1 PYRROLINE N OXIDE; 3,5 DIMETHYL 5 (PROPOXYCARBONYL) 1 PYRROLINE N OXIDE; 4,5 DIMETHYL 5 (ISOPROPOXYCARBONYL) 1 PYRROLINE N OXIDE; 4,5 DIMETHYL 5 (PROPOXYCARBONYL) 1 PYRROLINE N OXIDE; 5 (ETHOXYCARBONYL) 3,5 DIMETHYL 1 PYRROLINE N OXIDE; 5 (ETHOXYCARBONYL) 4,5 DIMETHYL 1 PYRROLINE N OXIDE; 5 BUTYL 5 (ETHOXYCARBONYL) 3 METHYL 1 PYRROLINE N OXIDE; 5 BUTYL 5 (ETHOXYCARBONYL) 4 METHYL 1 PYRROLINE N OXIDE; 5 DIETHOXYPHOSPHORYL 5 METHYL 1 PYRROLINE 1 OXIDE; 5 ETHOXYCARBONYL 3,5 DIMETHYLPYRROLINE N OXIDE; CARBONYL DERIVATIVE; CYTOTOXIC AGENT; PYRROLINE DERIVATIVE; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY TEST; ELECTRON SPIN RESONANCE; HUMAN; HUMAN CELL; NONHUMAN; RAT; SPIN TRAPPING;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; CELLS, CULTURED; CYCLIC N-OXIDES; HEPATOCYTES; HUMANS; HYDRO-LYASES; ISOMERISM; MOLECULAR STRUCTURE; NEOPLASMS; OXIDES; RATS; SPIN TRAPPING; STRUCTURE-ACTIVITY RELATIONSHIP; SUPEROXIDES;

EID: 34548561517     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.07.054     Document Type: Article

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