Spin trapping of lipid radicals with DEPMPO-derived spin traps: Detection of superoxide, alkyl and alkoxyl radicals in aqueous and lipid phase

Free Radical Biology and Medicine

Volumn 29, Issue 10, 2000, Pages 1005-1014

  Stolze, Klaus ^a   Udilova, Natascha ^a   Nohl, Hans ^a  

^a UNIVERSITY OF VETERINARY MEDICINE   (Austria)

Author keywords

DEPMPO; ESR; Free radicals; Linoleic acid hydroperoxide; Lipid peroxidation; Spin traps; Superoxide

Indexed keywords

5 (DI N BUTOXYPHOSPHORYL) 5 METHYL 1 PYRROLINE N OXIDE; 5 (DI N PROPOXYPHOSPHORYL) 5 METHYL 1 PYRROLINE N OXIDE; 5 [BIS (2 ETHYLHEXYLOXY)PHOSPHORYL] 5 METHYL 1 PYRROLINE N OXIDE; 5 DIETHOXYPHOSPHORYL 5 METHYL 1 PYRROLINE 1 OXIDE; DEFEROXAMINE MESYLATE; FERRIC ION; FERROUS ION; IRON COMPLEX; LINOLEIC ACID; LIPID HYDROPEROXIDE; METHANOL; PENTETIC ACID; PHOSPHATE; PYRROLINE DERIVATIVE; RADICAL; SUPEROXIDE; TERT BUTYL ALCOHOL; UNCLASSIFIED DRUG; WATER;

AQUEOUS SOLUTION; ARTICLE; CHEMICAL REACTION; COMPLEX FORMATION; CONCENTRATION RESPONSE; EXPERIMENTAL MODEL; HALF LIFE TIME; LIPID ANALYSIS; LIPID PEROXIDATION; LIPID SOLUBILITY; PRIORITY JOURNAL; SPIN TRAPPING;

CYCLIC N-OXIDES; DRUG STABILITY; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; LIPID PEROXIDATION; LIPIDS; SPIN LABELS; SUPEROXIDES;

EID: 0034669528     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(00)00401-9     Document Type: Article

References (25)

1. 5-(Diethoxyphosphoryl)-5-methyl-1-pyrroline N-Oxide: A new efficient phosphorylated nitrone for the in vitro and in vivo spin trapping of oxygen-centered radicals
2. Considerations in the spin trapping of superoxide and hydroxyl radical in aqueous systems using 5,5-dimethyl-1-pyrroline-1-oxide
3. Lipid peroxyl radicals from oxidized oils and heme-iron: Implication of a high-fat diet in colon carcinogenesis
4. Dietary polyunsaturated fatty acids and cancers of the breast and colorectum: Emerging evidence for their role as risk modifiers
5. Direct detection of free radicals in the reperfused rat heart using electron spin resonance spectroscopy
6. Stabilities of hydroxyl radical spin adducts of PBN-type spin traps
7. 31P-labeled cyclic nitrones: A new class of spin traps for free radicals in biological milieu
8. Characterization of sulfur-centered radical intermediates formed during the oxidation of thiols and sulfite by peroxynitrite
9. Intracellular mechanisms for the decomposition of a lipid peroxide. I. Decomposition of a lipid peroxide by metal ions, heme compounds, and nucleophiles
10. Reassignment of organic peroxyl radical adducts
11. Detection of free radicals produced from the reaction of cytochrome P-450 with linoleic acid hydroperoxide
12. Conversion of linoleic acid hydroperoxide to hydroxy, keto, epoxyhydroxy, and trihydroxy fatty acids by hematin
13. Carbon-centered free radical intermediates in the hematin- and ram seminal vesicle-catalyzed decomposition of fatty acid hydroperoxides
14. Epoxidation of 7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene via a hydroperoxide-dependent mechanism catalyzed by lipoxygenases
15. Alkyl free radicals from the β-scission of fatty acid alkoxyl radicals as detected by spin trapping in a lipoxygenase system
16. Superoxide and peroxyl radical generation from the reduction of polyunsaturated fatty acid hydroperoxides by soybean lipoxygenase
17. The fate of peroxyl radicals in aqueous solution
18. The elucidation of peroxyl radical reactions in aqueous solution with the help of radiation-chemical techniques
19. The formation of superoxide from organic peroxyl radicals. A potential contribution to transition metal ion-mediated damage
20. ESR spin trapping investigation of radical formation from the reaction between hematin and tert-butyl hydroperoxide
21. Bactericidal activity of alkyl peroxyl radicals generated by heme-iron-catalyzed decomposition of organic peroxides
22. A direct ESR and spin-trapping investigation of peroxyl free radical formation by hematin/hydroperoxide systems
23. Peroxyl, alkoxyl, and carbon-centered radical formation from organic hydroperoxides by chloroperoxidase
24. Detection of peroxyl and alkoxyl radicals produced by reaction of hydroperoxides with heme-proteins by ESR spectroscopy
25. Detection of peroxyl and alkoxyl radicals produced by reaction of hydroperoxides with rat liver microsomal fractions