Substrate specificity-conferring regions of the nonribosomal peptide synthetase adenylation domains involved in albicidin pathotoxin biosynthesis are highly conserved within the species Xanthomonas albilineans

Applied and Environmental Microbiology

Volumn 73, Issue 17, 2007, Pages 5523-5530

  Renier, Adeline ^a   Vivien, Eric ^a   Cociancich, Stéphane ^a   Letourmy, Philippe ^b   Perrier, Xavier ^b   Rott, Philippe C ^a   Royer, Monique ^a,b  

^a Campus International de Baillarguet   (France)

^b CIRAD   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATION; ALBICIDIN; ALBICIDIN PATHOTOXIN BIOSYNTHESIS; NONRIBOSOMAL PEPTIDE SYNTHETASE (NRPS); PATHOTOXIN BIOSYNTHESIS;

AMINO ACIDS; DNA; GENES; NUCLEOTIDES; PATHOGENS; PEPTIDES; POLYMORPHISM; SUBSTRATES;

ENZYMES;

ALBICIDIN; AMINO ACID; DNA FRAGMENT; NONRIBOSOMAL PEPTIDE SYNTHETASE; SYNTHETASE; TOXIN; UNCLASSIFIED DRUG;

AMINO ACID; BACTERIAL DISEASE; DNA; ENZYME ACTIVITY; GENETIC VARIATION; PATHOGENICITY; PHYLOGENETICS; POLYMORPHISM; SUGAR CANE; TOXIN;

ADENYLATION; AMINO ACID SEQUENCE; AMPLIFIED FRAGMENT LENGTH POLYMORPHISM; ARTICLE; ATPD GENE; BACTERIAL VIRULENCE; DNA POLYMORPHISM; EFP GENE; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; GENE AMPLIFICATION; GENETIC VARIABILITY; HOUSEKEEPING GENE; MUTATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PLANT DISEASE; PROTEIN DOMAIN; SEQUENCE ANALYSIS; SUGARCANE; TOXIN STRUCTURE; XANTHOMONAS; XANTHOMONAS ALBILINEANS;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CONSERVED SEQUENCE; DNA, BACTERIAL; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; MOLECULAR SEQUENCE DATA; ORGANIC CHEMICALS; PEPTIDE SYNTHASES; PLANT DISEASES; PROTEIN STRUCTURE, TERTIARY; SACCHARUM; SEQUENCE ANALYSIS, DNA; SUBSTRATE SPECIFICITY; VARIATION (GENETICS); XANTHOMONAS;

XANTHOMONAS ALBILINEANS;

EID: 34548514449     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/AEM.00577-07     Document Type: Article

References (34)

1. Birch, R. G. 2001. Xanthomonas albilineans and the antipathogenesis approach to disease control. Mol. Plant Pathol. 2:1-11.
2. Birch, R. G., and S. S. Patil. 1983. The relation of blocked chloroplast differentiation to sugarcane leaf scald disease. Phytopathology 73:1368-1374.
3. Birch, R. G., and S. S. Patil. June 1985. Antibiotic and process for the production thereof. U.S. patent 4,525,354.
4. Birch, R. G., and S. S. Patil. 1985. Preliminary characterization of an antibiotic produced by Xanthomonas albilineans which inhibits DNA synthesis in Escherichia coli. J. Gen. Microbiol. 131:1069-1075.
5. Birch, R. G., and S. S. Patil. 1987. Correlation between albicidin production and chlorosis induction by Xanthomonas albilineans, the sugarcane leaf scald pathogen. Physiol. Mol. Plant Pathol. 30:199-206.
6. Birch, R. G., and S. S. Patil. 1987. Evidence that an albicidin-like phytotoxin induces chlorosis in sugarcane leaf scald disease by blocking plastid DNA replication. Physiol. Mol. Plant Pathol. 30:207-214.
7. Cane, D. E., and C. T. Walsh. 1999. The parallel and convergent universes of polyketide synthases and nonribosomal peptide synthetases. Chem. Biol. 6:319-325.
8. Challis, G. L., J. Ravel, and C. A. Townsend. 2000. Predictive, structure-based model of amino acid recognition by nonribosomal peptide synthetase adenylation domains. Chem. Biol. 7:211-224.
9. Champoiseau, P., J.-H. Daugrois, J.-C. Girard, M. Royer, and P. Rott. 2006. Variation in albicidin biosynthesis genes and in pathogenicity of Xanthomonas albilineans, the sugarcane leaf scald pathogen. Phytopathology 96:33-45.
10. Champoiseau, P., J.-H. Daugrois, I. Pieretti, S. Cociancich, M. Royer, and P. Rott. 2006. High variation in pathogenicity of genetically closely related strains of Xanthomonas albilineans, the sugarcane leaf scald pathogen, in Guadeloupe. Phytopathology 96:1081-1091.
11. Christensen, H., and J. E. Olsen. 1998. Phylogenetic relationships of Salmonella based on DNA sequence comparison of atpD encoding the β subunit of ATP synthase. FEMS Microbiol. Lett. 161:89-96.
12. Conover, W. J., and R. L. Iman. 1981. Rank transformations as a bridge between parametric and nonparametric statistics. Am. Stat. 35:124-129.
13. Conti, E., T. Stachelhaus, M. A. Marahiel, and P. Brick. 1997. Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S. EMBO J. 16:4174-4183.
14. Davis, M. J., P. Rott, C. J. Warmuth, M. Chatenet, and P. Baudin. 1997. Intraspecific genomic variation within Xanthomonas albilineans, the sugarcane leaf scald pathogen. Phytopathology 87:316-324.
15. Du, L., and B. Shen. 2001. Biosynthesis of hybrid peptide-polyketide natural products. Curr. Opin. Drug Discov. Devel. 4:215-228.
16. Hall, T. A. 1999. BioEdit: a user-friendly biological sequence alignments editor and analysis program for Windows 95/98/NT. Nucleic Acids Symp. Ser. 41:95-98.
17. Hashimi, S. M., M. K. Wall, A. B. Smith, A. Maxwell, and R. G. Birch. 2007. The phytotoxin albicidin is a novel inhibitor of DNA gyrase. Antimicrob. Agents Chemother. 51:181-187.
18. Huang, G., L. Zhang, and R. G. Birch. 2001. A multifunctional polyketide-peptide synthetase essential for albicidin biosynthesis in Xanthomonas albilineans. Microbiology 147:631-642.
19. Jordan, K. I., I. B. Rogozin, Y. I. Wolf, and E. V. Koonin. 2002. Microevolutionary genomics of bacteria. Theor. Popul. Biol. 61:435-447.
20. Jukes, T. H., and C. R. Cantor. 1969. Evolution of protein molecules, p. 21-132. In H. N. Munro (ed.), Mammalian protein metabolism. Academic Press, New York, NY.
21. May, J. J., N. Kessler, M. A. Marahiel, and M. T. Stubbs. 2002. Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases. Proc. Natl. Acad. Sci. USA 99:12120-12125.
22. Perrier, X., A. Flori, and F. Bonnot. 2003. Data analysis methods, p. 43-76. In P. Hamon, M. Seguin, X. Perrier, and J. C. Glaszmann (ed.), Genetic diversity of cultivated tropical plants. Cirad, Montpellier, France.
23. Pride, D. T., and M. J. Blaser. 2002. Concerted evolution between duplicated genetic elements in Helicobacter pylori. J. Mol. Biol. 316:629-642.
24. Ricaud, C., and C. C. Ryan. 1989. Leaf scald, p. 39-58. In C. Ricaud, B. T. Egan, A. G. Gillaspie, Jr., and C. G. Hughes (ed.), Diseases of sugarcane: major diseases. Elsevier, Amsterdam, The Netherlands.
25. Rott, P., and M. J. Davis. 2000. Leaf scald, p. 38-44. In P. Rott, R. A. Bailey, J. C. Comstock, B. J. Croft, and A. S. Saumtally (ed.), A guide to sugarcane diseases. La Librairie du Cirad, Montpellier, France.
26. Rott, P., M. Abel, D. Soupa, P. Feldmann, and P. Letourmy. 1994. Population dynamics of Xanthomonas albilineans in sugarcane plants as determined with an antibiotic-resistant mutant. Plant Dis. 78:241-247.
27. Rott, P. C., L. Costet, M. J. Davis, R. Frutos, and D. W. Gabriel. 1996. At least two gene clusters are involved in albicidin production by Xanthomonas albilineans. J. Bacteriol. 178:4590-4596.
28. Royer, M., L. Costet, E. Vivien, M. Bes, A. Cousin, I. Pieretti, A. Savin, S. Megessier, M. Viard, R. Frutos, D. W. Gabriel, and P. C. Rott. 2004. Albicidin pathotoxin produced by Xanthomonas albilineans is encoded by three large PKS and NRPS genes present in a gene cluster containing also several putative modifying, regulatory and resistance genes. Mol. Plant-Microbe Interact. 17:414-427.
29. Saitou, N., and M. Nei. 1987. The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol. Biol. Evol. 4:406-425.
30. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
31. Sieber, S. A., and M. A. Marahiel. 2005. Molecular mechanisms underlying nonribosomal peptide synthesis: approaches to new antibiotics. Chem. Rev. 105:715-738.
32. Stachelhaus, T., H. D. Mootz, and M. A. Marahiel. 1999. The specificity-conferring code of adenylation domains in nonribosomal peptide synthetases. Chem. Biol. 6:493-505.
33. Vivien, E., D. Pitorre, S. Cociancich, I. Pieretti, D. W. Gabriel, P. C. Rott, and M. Royer. 2007. Heterologous production of albicidin: a promising approach to overproducing and characterizing this potent inhibitor of DNA gyrase. Antimicrob. Agents Chemother. 51:1549-1552.
34. Yang, P., P. Rott, L. Vauterin, B. Hoste, P. Baudin, K. Kersters, and J. Swings. 1993. Intraspecific variability of Xanthomonas albilineans. Syst. Appl. Microbiol. 16:420-426.