메뉴 건너뛰기




Volumn 51, Issue 1, 2007, Pages 181-187

The phytotoxin albicidin is a novel inhibitor of DNA gyrase

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALBICIDIN; ANTIBIOTIC AGENT; CIPROFLOXACIN; COUMARIN; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE IV; GYRASE INHIBITOR; MICROCIN B17; NOVOBIOCIN; PLANT TOXIN; PROTEIN CCDB; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG;

EID: 33846032702     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00918-06     Document Type: Article
Times cited : (88)

References (50)
  • 2
    • 0028952815 scopus 로고
    • A gene from Alcaligenes denitrificans that confers albicidin resistance by reversible antibiotic binding
    • Basnayake, W. V. S., and R. G. Birch. 1995. A gene from Alcaligenes denitrificans that confers albicidin resistance by reversible antibiotic binding. Microbiology 141:551-560.
    • (1995) Microbiology , vol.141 , pp. 551-560
    • Basnayake, W.V.S.1    Birch, R.G.2
  • 3
    • 0030063743 scopus 로고    scopus 로고
    • Energy coupling in Escherichia coli DNA gyrase: The relationship between nucleotide binding, strand passage, and DNA supercoiling
    • Bates, A. D., M. H. Odea, and M. Gellert. 1996. Energy coupling in Escherichia coli DNA gyrase: the relationship between nucleotide binding, strand passage, and DNA supercoiling. Biochemistry 35:1408-1416.
    • (1996) Biochemistry , vol.35 , pp. 1408-1416
    • Bates, A.D.1    Odea, M.H.2    Gellert, M.3
  • 4
    • 0028979665 scopus 로고
    • New ccdB positive-selection cloning vectors with kanamycin or chloramphenicol selectable markers
    • Bernard, P. 1995. New ccdB positive-selection cloning vectors with kanamycin or chloramphenicol selectable markers. Gene 162:159-160.
    • (1995) Gene , vol.162 , pp. 159-160
    • Bernard, P.1
  • 5
    • 0026728290 scopus 로고
    • Cell killing by the F plasmid CcdB protein involves poisoning of DNA-topoisomerase II complexes
    • Bernard, P., and M. Couturier. 1992. Cell killing by the F plasmid CcdB protein involves poisoning of DNA-topoisomerase II complexes. J. Mol. Biol. 226:735-745.
    • (1992) J. Mol. Biol , vol.226 , pp. 735-745
    • Bernard, P.1    Couturier, M.2
  • 6
    • 0035039660 scopus 로고    scopus 로고
    • Xanthomonas albilineans and the antipathogenesis approach to disease control
    • Birch, R. G. 2001. Xanthomonas albilineans and the antipathogenesis approach to disease control. Mol. Plant Pathol. 2:1-11.
    • (2001) Mol. Plant Pathol , vol.2 , pp. 1-11
    • Birch, R.G.1
  • 7
    • 0003895191 scopus 로고
    • Antibiotic and process for the production thereof
    • 25 June, U.S. patent 4525354
    • Birch, R. G., and S. S. Patil. 25 June 1985. Antibiotic and process for the production thereof. U.S. patent 4525354.
    • (1985)
    • Birch, R.G.1    Patil, S.S.2
  • 8
    • 0001033786 scopus 로고
    • Correlation between albicidin production and chlorosis induction by Xanthomonas albilineans, the sugarcane leaf scald pathogen
    • Birch, R. G., and S. S. Patil. 1987. Correlation between albicidin production and chlorosis induction by Xanthomonas albilineans, the sugarcane leaf scald pathogen. Physiol. Mol. Plant Pathol. 30:199-206.
    • (1987) Physiol. Mol. Plant Pathol , vol.30 , pp. 199-206
    • Birch, R.G.1    Patil, S.S.2
  • 9
    • 0000474539 scopus 로고
    • Evidence that an albicidin-like phytotoxin induces chlorosis in sugarcane leaf scald disease by blocking plastid DNA replication
    • Birch, R. G., and S. S. Patil. 1987. Evidence that an albicidin-like phytotoxin induces chlorosis in sugarcane leaf scald disease by blocking plastid DNA replication. Physiol. Mol. Plant Pathol. 30:207-214.
    • (1987) Physiol. Mol. Plant Pathol , vol.30 , pp. 207-214
    • Birch, R.G.1    Patil, S.S.2
  • 10
    • 0021824397 scopus 로고
    • Preliminary characterization of an antibiotic produced by Xanthomonas albilineans which inhibits DNA synthesis in Escherichia coli
    • Birch, R. G., and S. S. Patil. 1985. Preliminary characterization of an antibiotic produced by Xanthomonas albilineans which inhibits DNA synthesis in Escherichia coli. J. Gen. Microbiol. 131:1069-1075.
    • (1985) J. Gen. Microbiol , vol.131 , pp. 1069-1075
    • Birch, R.G.1    Patil, S.S.2
  • 11
    • 0005603002 scopus 로고
    • The relation of blocked chloroplast differentiation to sugarcane leaf scald disease
    • Birch, R. G., and S. S. Patil. 1983. The relation of blocked chloroplast differentiation to sugarcane leaf scald disease. Phytopathology 73:1368-1374.
    • (1983) Phytopathology , vol.73 , pp. 1368-1374
    • Birch, R.G.1    Patil, S.S.2
  • 12
    • 0025136772 scopus 로고
    • Stable albicidin resistance in Escherichia coli involves an altered outer membrane nucleoside uptake system
    • Birch, R. G., J. M. Pemberton, and W. V. S. Basnayake. 1990. Stable albicidin resistance in Escherichia coli involves an altered outer membrane nucleoside uptake system. J. Gen. Microbiol. 136:51-58.
    • (1990) J. Gen. Microbiol , vol.136 , pp. 51-58
    • Birch, R.G.1    Pemberton, J.M.2    Basnayake, W.V.S.3
  • 13
    • 0018617661 scopus 로고
    • Plasmids of Escherichia coli as cloning vectors
    • Bolivar, F., and K. Backman. 1979. Plasmids of Escherichia coli as cloning vectors. Methods Enzymol. 68:245-267.
    • (1979) Methods Enzymol , vol.68 , pp. 245-267
    • Bolivar, F.1    Backman, K.2
  • 14
    • 33745472226 scopus 로고    scopus 로고
    • A DHA14 drug efflux gene from Xanthomonas albilineans confers high-level albicidin antibiotic resistance in Escherichia coli
    • Bostock, J. M., G. Huang, S. M. Hashimi, L. H. Zhang, and R. G. Birch. 2006. A DHA14 drug efflux gene from Xanthomonas albilineans confers high-level albicidin antibiotic resistance in Escherichia coli. J. Appl. Microbiol. 101:151-160.
    • (2006) J. Appl. Microbiol , vol.101 , pp. 151-160
    • Bostock, J.M.1    Huang, G.2    Hashimi, S.M.3    Zhang, L.H.4    Birch, R.G.5
  • 16
    • 0026648204 scopus 로고
    • GyrB mutations which confer coumarin resistance also affect DNA supercoiling and ATP hydrolysis by Escherichia coli DNA gyrase
    • Contreras, A., and A. Maxwell. 1992. GyrB mutations which confer coumarin resistance also affect DNA supercoiling and ATP hydrolysis by Escherichia coli DNA gyrase. Mol. Microbiol. 6:1617-1624.
    • (1992) Mol. Microbiol , vol.6 , pp. 1617-1624
    • Contreras, A.1    Maxwell, A.2
  • 17
    • 2442599792 scopus 로고    scopus 로고
    • Structure, molecular mechanisms, and evolutionary relationships in DNA topoisomerases
    • Corbett, K. D., and J. M. Berger. 2004. Structure, molecular mechanisms, and evolutionary relationships in DNA topoisomerases. Annu. Rev. Biophys. Biomol. Struct. 33:95-118.
    • (2004) Annu. Rev. Biophys. Biomol. Struct , vol.33 , pp. 95-118
    • Corbett, K.D.1    Berger, J.M.2
  • 18
    • 0031558807 scopus 로고    scopus 로고
    • The interaction of the F plasmid killer protein, CcdB, with DNA gyrase: Induction of DNA cleavage and blocking of transcription
    • Critchlow, S. E., M. H. O'Dea, A. J. Howells, M. Couturier, M. Gellert, and A. Maxwell. 1997. The interaction of the F plasmid killer protein, CcdB, with DNA gyrase: induction of DNA cleavage and blocking of transcription. J. Mol. Biol. 273:826-839.
    • (1997) J. Mol. Biol , vol.273 , pp. 826-839
    • Critchlow, S.E.1    O'Dea, M.H.2    Howells, A.J.3    Couturier, M.4    Gellert, M.5    Maxwell, A.6
  • 21
    • 0036093581 scopus 로고    scopus 로고
    • Quinolone-binding pocket of DNA gyrase: Role of GyrB
    • Heddle, J., and A. Maxwell. 2002. Quinolone-binding pocket of DNA gyrase: role of GyrB. Antimicrob. Agents Chemother. 46:1805-1815.
    • (2002) Antimicrob. Agents Chemother , vol.46 , pp. 1805-1815
    • Heddle, J.1    Maxwell, A.2
  • 22
    • 0033736170 scopus 로고    scopus 로고
    • The interaction of drugs with DNA gyrase: A model for the molecular basis of quinolone action
    • Heddle, J. G., F. M. Barnard, L. M. Wentzell, and A. Maxwell. 2000. The interaction of drugs with DNA gyrase: a model for the molecular basis of quinolone action. Nucleosides Nucleotides Nucleic Acids 19:1249-1264.
    • (2000) Nucleosides Nucleotides Nucleic Acids , vol.19 , pp. 1249-1264
    • Heddle, J.G.1    Barnard, F.M.2    Wentzell, L.M.3    Maxwell, A.4
  • 24
    • 0034722672 scopus 로고    scopus 로고
    • Albicidin antibiotic and phytotoxin biosynthesis in Xanthomonas albilineans requires a phosphopantetheinyl transferase gene
    • Huang, G., L. Zhang, and R. G. Birch. 2000. Albicidin antibiotic and phytotoxin biosynthesis in Xanthomonas albilineans requires a phosphopantetheinyl transferase gene. Gene 258:193-199.
    • (2000) Gene , vol.258 , pp. 193-199
    • Huang, G.1    Zhang, L.2    Birch, R.G.3
  • 25
    • 0034687103 scopus 로고    scopus 로고
    • Analysis of the genes flanking xabB: A methyltransferase gene is involved in albicidin biosynthesis in Xanthomonas albilineans
    • Huang, G., L. Zhang, and R. G. Birch. 2000. Analysis of the genes flanking xabB: a methyltransferase gene is involved in albicidin biosynthesis in Xanthomonas albilineans. Gene 255:327-333.
    • (2000) Gene , vol.255 , pp. 327-333
    • Huang, G.1    Zhang, L.2    Birch, R.G.3
  • 26
    • 0035083883 scopus 로고    scopus 로고
    • A multifunctional polyketide-peptide synthase for albicidin biosynthesis in Xanthomonas albilineans
    • Huang, G., L. Zhang, and R. G. Birch. 2001. A multifunctional polyketide-peptide synthase for albicidin biosynthesis in Xanthomonas albilineans. Microbiology 147:631-642.
    • (2001) Microbiology , vol.147 , pp. 631-642
    • Huang, G.1    Zhang, L.2    Birch, R.G.3
  • 27
    • 33748329473 scopus 로고    scopus 로고
    • Lethal fragmentation of bacterial chromosomes mediated by DNA gyrase and quinolones
    • Malik, M., X. Zhao, and K. Drlica. 2006. Lethal fragmentation of bacterial chromosomes mediated by DNA gyrase and quinolones. Mol. Microbiol. 61:810-825.
    • (2006) Mol. Microbiol , vol.61 , pp. 810-825
    • Malik, M.1    Zhao, X.2    Drlica, K.3
  • 28
    • 0031105464 scopus 로고    scopus 로고
    • DNA gyrase as a drug target
    • Maxwell, A. 1997. DNA gyrase as a drug target. Trends Microbiol. 5:102-109.
    • (1997) Trends Microbiol , vol.5 , pp. 102-109
    • Maxwell, A.1
  • 29
    • 0012684806 scopus 로고    scopus 로고
    • The ATP-binding site of type II topoisomerases as a target for antibacterial drugs
    • Maxwell, A., and D. M. Lawson. 2003. The ATP-binding site of type II topoisomerases as a target for antibacterial drugs. Curr. Top. Med. Chem. 3:283-303.
    • (2003) Curr. Top. Med. Chem , vol.3 , pp. 283-303
    • Maxwell, A.1    Lawson, D.M.2
  • 31
    • 3242690878 scopus 로고    scopus 로고
    • Monteiro-Vitorello, C. B, L. E. A. Camargo, M. A. Van Sluys, J. P. Kitajima, D. Truffi, A. M. do Amaral, R. Harakava, J. C. F. de Oliveira, D. Wood, M. C. de Oliveira, C. Miyaki, M. A. Takita, A. C. R. da Silva, L. R. Furlan, D. M. Carraro, G. Camarotte, N. F. Almeida, H. Carrer, L. L. Coutinho, H. A. El-Dorry, M. I. T. Ferro, P. R. Gagliardi, E. Giglioti, M. H. S. Goldman, G. H. Goldman, E. T. Kimura, E. S. Ferro, E. E. Kuramae, E. G. M. Lemos, M. V. F. Lemos, S. M. Z. Mauro, M. A. Machado, C. L. Marino, C. F. Menck, L. R. Nunes, R. C. Oliveira, G. G. Pereira, W. Siqueira, A. A. de Souza, S. M. Tsai, A. S. Zanca, A. J. G. Simpson, S. M. Brumbley, and J. C. Setubal. 2004. The genome sequence of the gram-positive sugarcane pathogen Leifsonia xyli subsp. xyli. Mol. Plant-Microbe Interact. 17:827-836
    • Monteiro-Vitorello, C. B., L. E. A. Camargo, M. A. Van Sluys, J. P. Kitajima, D. Truffi, A. M. do Amaral, R. Harakava, J. C. F. de Oliveira, D. Wood, M. C. de Oliveira, C. Miyaki, M. A. Takita, A. C. R. da Silva, L. R. Furlan, D. M. Carraro, G. Camarotte, N. F. Almeida, H. Carrer, L. L. Coutinho, H. A. El-Dorry, M. I. T. Ferro, P. R. Gagliardi, E. Giglioti, M. H. S. Goldman, G. H. Goldman, E. T. Kimura, E. S. Ferro, E. E. Kuramae, E. G. M. Lemos, M. V. F. Lemos, S. M. Z. Mauro, M. A. Machado, C. L. Marino, C. F. Menck, L. R. Nunes, R. C. Oliveira, G. G. Pereira, W. Siqueira, A. A. de Souza, S. M. Tsai, A. S. Zanca, A. J. G. Simpson, S. M. Brumbley, and J. C. Setubal. 2004. The genome sequence of the gram-positive sugarcane pathogen Leifsonia xyli subsp. xyli. Mol. Plant-Microbe Interact. 17:827-836.
  • 32
    • 0035180104 scopus 로고    scopus 로고
    • Intrinsic resistance of Mycobacterium smegmatis to fluoroquinolones may be influenced by new pentapeptide protein MfpA
    • Montero, C., G. Mateu, R. Rodriguez, and H. Takiff. 2001. Intrinsic resistance of Mycobacterium smegmatis to fluoroquinolones may be influenced by new pentapeptide protein MfpA. Antimicrob. Agents Chemother. 45:3387-3392.
    • (2001) Antimicrob. Agents Chemother , vol.45 , pp. 3387-3392
    • Montero, C.1    Mateu, G.2    Rodriguez, R.3    Takiff, H.4
  • 33
    • 0041816347 scopus 로고    scopus 로고
    • The action of the bacterial toxin microcin B17-insight into the cleavage-religation reaction of DNA gyrase
    • Pierrat, O. A., and A. Maxwell. 2003. The action of the bacterial toxin microcin B17-insight into the cleavage-religation reaction of DNA gyrase. J. Biol. Chem. 278:35016-35023.
    • (2003) J. Biol. Chem , vol.278 , pp. 35016-35023
    • Pierrat, O.A.1    Maxwell, A.2
  • 34
    • 15544388505 scopus 로고    scopus 로고
    • Evidence for the role of DNA strand passage in the mechanism of action of microcin B17 on DNA gyrase
    • Pierrat, O. A., and A. Maxwell. 2005. Evidence for the role of DNA strand passage in the mechanism of action of microcin B17 on DNA gyrase. Biochemistry 44:4204-4215.
    • (2005) Biochemistry , vol.44 , pp. 4204-4215
    • Pierrat, O.A.1    Maxwell, A.2
  • 35
    • 0024398661 scopus 로고
    • Tryptic fragments of the Escherichia coli DNA gyrase A protein
    • Reece, R. J., and A. Maxwell. 1989. Tryptic fragments of the Escherichia coli DNA gyrase A protein. J. Biol. Chem. 264:19648-19653.
    • (1989) J. Biol. Chem , vol.264 , pp. 19648-19653
    • Reece, R.J.1    Maxwell, A.2
  • 36
    • 12144291588 scopus 로고    scopus 로고
    • Albicidin pathotoxin produced by Xanthomonas albilineans is encoded by three large PKS and NRPS genes present in a gene cluster also containing several putative modifying, regulatory, and resistance genes
    • Royer, M., L. Costet, E. Vivien, M. Bes, A. Cousin, A. Damais, I. Pieretti, A. Savin, S. Megessier, M. Viard, R. Frutos, D. W. Gabriel, and P. C. Rott. 2004. Albicidin pathotoxin produced by Xanthomonas albilineans is encoded by three large PKS and NRPS genes present in a gene cluster also containing several putative modifying, regulatory, and resistance genes. Mol. Plant-Microbe Interact. 17:414-427.
    • (2004) Mol. Plant-Microbe Interact , vol.17 , pp. 414-427
    • Royer, M.1    Costet, L.2    Vivien, E.3    Bes, M.4    Cousin, A.5    Damais, A.6    Pieretti, I.7    Savin, A.8    Megessier, S.9    Viard, M.10    Frutos, R.11    Gabriel, D.W.12    Rott, P.C.13
  • 39
    • 33750206130 scopus 로고    scopus 로고
    • A strand-passage conformation of DNA gyrase is required to allow the bacterial toxin, CcdB, to access its binding site
    • Smith, A. B., and A. Maxwell. 2006. A strand-passage conformation of DNA gyrase is required to allow the bacterial toxin, CcdB, to access its binding site. Nucleic Acids Res. 34:4667-4676.
    • (2006) Nucleic Acids Res , vol.34 , pp. 4667-4676
    • Smith, A.B.1    Maxwell, A.2
  • 40
    • 0026688325 scopus 로고
    • Tagetitoxin inhibition of RNA polymerase III transcription results from enhanced pausing at discrete sites and is template dependent
    • Steinberg, T. H., and R. R. Burgess. 1992. Tagetitoxin inhibition of RNA polymerase III transcription results from enhanced pausing at discrete sites and is template dependent. J. Biol. Chem. 267:20204-20211.
    • (1992) J. Biol. Chem , vol.267 , pp. 20204-20211
    • Steinberg, T.H.1    Burgess, R.R.2
  • 41
    • 0037117605 scopus 로고    scopus 로고
    • Mechanism of plasmid-mediated quinolone resistance
    • Tran, J. H., and G. A. Jacoby. 2002. Mechanism of plasmid-mediated quinolone resistance. Proc. Natl. Acad. Sci. USA 99:5638-5642.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 5638-5642
    • Tran, J.H.1    Jacoby, G.A.2
  • 42
    • 0024041853 scopus 로고
    • Cloning and characterization of an albicidin resistance gene from Klebsiella oxytoca
    • Walker, M. J., R. G. Birch, and J. M. Pemberton. 1988. Cloning and characterization of an albicidin resistance gene from Klebsiella oxytoca. Mol. Microbiol. 2:443-454.
    • (1988) Mol. Microbiol , vol.2 , pp. 443-454
    • Walker, M.J.1    Birch, R.G.2    Pemberton, J.M.3
  • 43
    • 0030968445 scopus 로고    scopus 로고
    • Genes for albicidin biosynthesis and resistance span at least 69 kb in the genome of Xanthomonas albilineans
    • Wall, M. K., and R. G. Birch. 1997. Genes for albicidin biosynthesis and resistance span at least 69 kb in the genome of Xanthomonas albilineans. Lett. Appl. Microbiol. 24:256-260.
    • (1997) Lett. Appl. Microbiol , vol.24 , pp. 256-260
    • Wall, M.K.1    Birch, R.G.2
  • 44
    • 2442717681 scopus 로고    scopus 로고
    • Arabidopsis thaliana DNA gyrase is targeted to chloroplasts and mitochondria
    • Wall, M. K., L. A. Mitchenall, and A. Maxwell. 2004. Arabidopsis thaliana DNA gyrase is targeted to chloroplasts and mitochondria. Proc. Natl. Acad. Sci. USA 101:7821-7826.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 7821-7826
    • Wall, M.K.1    Mitchenall, L.A.2    Maxwell, A.3
  • 45
    • 0034671255 scopus 로고    scopus 로고
    • The complex of DNA gyrase and quinolone drugs on DNA forms a barrier to the T7 DNA polymerase replication complex
    • Wentzell, L. M., and A. Maxwell. 2000. The complex of DNA gyrase and quinolone drugs on DNA forms a barrier to the T7 DNA polymerase replication complex. J. Mol. Biol. 304:779-791.
    • (2000) J. Mol. Biol , vol.304 , pp. 779-791
    • Wentzell, L.M.1    Maxwell, A.2
  • 46
    • 0035830951 scopus 로고    scopus 로고
    • Locking the ATP-operated clamp of DNA gyrase: Probing the mechanism of strand passage
    • Williams, N. L., A. J. Howells, and A. Maxwell. 2001. Locking the ATP-operated clamp of DNA gyrase: probing the mechanism of strand passage. J. Mol. Biol. 306:969-984.
    • (2001) J. Mol. Biol , vol.306 , pp. 969-984
    • Williams, N.L.1    Howells, A.J.2    Maxwell, A.3
  • 47
    • 0025282176 scopus 로고
    • Quinolone resistance-determining region in the DNA gyarse gyrA gene of Escherichia coli
    • Yoshida, H., M. Bogaki, M. Nakamura, and S. Nakamura. 1990. Quinolone resistance-determining region in the DNA gyarse gyrA gene of Escherichia coli. Antimicrob. Agents Chemother. 34:1271-1272.
    • (1990) Antimicrob. Agents Chemother , vol.34 , pp. 1271-1272
    • Yoshida, H.1    Bogaki, M.2    Nakamura, M.3    Nakamura, S.4
  • 48
    • 0030984218 scopus 로고    scopus 로고
    • The gene for albicidin detoxification from Pantoea dispersa encodes an esterase and attenuates pathogenicity of Xanthomonas albilineans to sugarcane
    • Zhang, L., and R. G. Birch. 1997. The gene for albicidin detoxification from Pantoea dispersa encodes an esterase and attenuates pathogenicity of Xanthomonas albilineans to sugarcane. Proc. Natl. Acad. Sci. USA 94:9984-9989.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9984-9989
    • Zhang, L.1    Birch, R.G.2
  • 49
    • 0032851627 scopus 로고    scopus 로고
    • Engineered detoxification confers resistance against a pathogenic bacterium
    • Zhang, L., J. Xu, and R. G. Birch. 1999. Engineered detoxification confers resistance against a pathogenic bacterium. Nat. Biotechnol. 17:1021-1024.
    • (1999) Nat. Biotechnol , vol.17 , pp. 1021-1024
    • Zhang, L.1    Xu, J.2    Birch, R.G.3
  • 50
    • 0031742555 scopus 로고    scopus 로고
    • Factors affecting biosynthesis by Xanthomonas albilineans of albicidin antibiotics and phytotoxins
    • Zhang, L., J. Xu, and R. G. Birch. 1998. Factors affecting biosynthesis by Xanthomonas albilineans of albicidin antibiotics and phytotoxins. J. Appl. Microbiol. 85:1023-1028.
    • (1998) J. Appl. Microbiol , vol.85 , pp. 1023-1028
    • Zhang, L.1    Xu, J.2    Birch, R.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.