Plant-derived human acetylcholinesterase-R provides protection from lethal organophosphate poisoning and its chronic aftermath

FASEB Journal

Volumn 21, Issue 11, 2007, Pages 2961-2969

  Evron, Tama ^b   Geyer, Brian C ^a   Cherni, Irene ^a   Muralidharan, Mrinalini ^a   Kilbourne, Jacquelyn ^a   Fletcher, Samuel P ^a   Soreq, Hermona ^b   Mor, Tsafrir S ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Bioscavenger; Long term protection; Neuromuscular junction; Paraoxon intoxication; Transgenic plants

Indexed keywords

ACETYLCHOLINESTERASE; ENZYME VARIANT; ORGANOPHOSPHATE; PARAOXON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ENDOPLASMIC RETICULUM; ENZYME PURIFICATION; ENZYME SYNTHESIS; IC 50; IN VIVO STUDY; INTOXICATION; LETHAL DOSE; MALE; MAMMAL CELL; MOUSE; NEUROMUSCULAR JUNCTION DISORDER; NICOTIANA BENTHAMIANA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TOBACCO; UPREGULATION;

ACETYLCHOLINESTERASE; ANIMALS; BINDING SITES; HUMANS; INSECTICIDES; LETHAL DOSE 50; MALE; MICE; MUSCLE, SKELETAL; NEUROMUSCULAR JUNCTION; ORGANOPHOSPHORUS COMPOUNDS; PARAOXON; PLANTS, GENETICALLY MODIFIED; POLYETHYLENE GLYCOLS; RECOMBINANT PROTEINS; SURVIVAL RATE; TISSUE DISTRIBUTION; TOBACCO;

MAMMALIA; MURINAE; MUS; NICOTIANA BENTHAMIANA;

EID: 34548490940     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.07-8112com     Document Type: Article

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