Acetylcholinesterase enhances neurite growth and synapse development through alternative contributions of its hydrolytic capacity, core protein, and variable C termini

Journal of Neuroscience

Volumn 18, Issue 4, 1998, Pages 1240-1249

  Sternfeld, Meira ^a   Ming, Guo Li ^b   Song, Hong Jun ^a   Sela, Keren ^a   Timberg, Rina ^b   Poo, Mu Ming ^a   Soreq, Hermona ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Acetylcholinesterase; Alternative C termini; Neurite extension; Neurogenesis; Neuromuscular junctions; Noncatalytic function; Synaptogenesis; Xenopus spinal neurons

Indexed keywords

ACETYLCHOLINESTERASE; CORE PROTEIN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL MIGRATION; ELECTRON MICROSCOPY; ENZYME ACTIVATION; GENE SEQUENCE; GENOME; HYDROLYSIS; IMMUNOHISTOCHEMISTRY; NERVE FIBER GROWTH; NERVOUS SYSTEM DEVELOPMENT; NEUROMUSCULAR SYNAPSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; RNA SPLICING; SYNAPTOGENESIS; XENOPUS LAEVIS;

EID: 0032520131     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-04-01240.1998     Document Type: Article

References (3)

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2. Andres C, Beeri R, Friedman A, Lev-Lehman E, Henis S, Timberg R, Shani M, Soreq H (1997) Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Iβ gene expression followed by late-onset neuromotor degeneration. Proc Natl Acad Sci USA 95:8173-8178.
3. Auld VJ, Fetter RD, Broadie K, Goodman CS (1995) Gliotactin, a novel transmembrane protein on peripheral glia, is required to form the blood-nerve barrier in Drosophila. Cell 81:757-767.