Role of conserved active site residues in catalysis by phospholipase B1 from Cryptococcus neoformans

Biochemistry

Volumn 46, Issue 35, 2007, Pages 10024-10032

  Jones, Peter M ^a   Turner, Kylie M ^b   Djordjevic, Julianne T ^b   Sorrell, Tania C ^b   Wright, Lesley C ^b   George, Anthony M ^a  

^a UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CRYPTOCOCCUS NEOFORMANS; PHOSPHOLIPASE B1; PUTATIVE CATALYTIC; SUBTILISIN PROTEASE ASPARTATE;

CATALYSIS; DNA; MUTAGENS; PATHOGENS; PROTEINS; X RAY ANALYSIS; YEAST;

PHOSPHOLIPIDS;

ACYLTRANSFERASE; ALANINE; ARACHIDONIC ACID; ASPARTIC ACID; COMPLEMENTARY DNA; LYSOPHOSPHOLIPASE; PALMITIC ACID; PHOSPHOLIPASE; PHOSPHOLIPASE A2; PHOSPHOLIPASE B1; SUBTILISIN; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

ACYLTRANSFERASES; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARGININE; ASPARAGINE; BINDING SITES; CATALYSIS; CONSENSUS SEQUENCE; CRYPTOCOCCUS NEOFORMANS; CYTOSOL; GENES, FUNGAL; HUMANS; LYSOPHOSPHOLIPASE; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MULTIENZYME COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PHOSPHOLIPASES A2; PHOSPHOLIPIDS; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY, AMINO ACID; SERINE; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY; VIRULENCE;

FILOBASIDIELLA NEOFORMANS; SACCHAROMYCES CEREVISIAE;

EID: 34548475775     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi7009508     Document Type: Article

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