Functional identification of the active-site nucleophile of the human 85-kDa cytosolic phospholipase A2

Biochemistry

Volumn 35, Issue 12, 1996, Pages 3712-3721

  Huang, Zheng ^a   Fayette, Paul ^a   Abdullah, Khalid ^a,b   Cromlish, Wanda A ^a   Kennedy, Brian P ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^b AMCO Pharmaceuticals Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM IONOPHORE; ESTERASE; FLUOROPHOSPHATE; PHOSPHOLIPASE A2; PROSTAGLANDIN E2; UMBELLIFERONE;

ANIMAL CELL; ARTICLE; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; GENE EXPRESSION REGULATION; HUMAN; LIPID TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; ARACHIDONIC ACID; BASE SEQUENCE; BINDING SITES; CELL LINE; CHROMATOGRAPHY, AFFINITY; CYTOPLASM; DINOPROSTONE; ENZYME INHIBITORS; GAMMA-LINOLENIC ACID; HUMANS; IMMUNOBLOTTING; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHOLIPASES A; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; SERINE; TRANSFECTION;

EID: 0029879110     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952541k     Document Type: Article

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