The COX-2 inhibitor SC-236 exerts anti-inflammatory effects by suppressing phosphorylation of ERK in a murine model

Life Sciences

Volumn 81, Issue 11, 2007, Pages 863-872

  Kim, Su Jin ^a,c   Jeong, Hyun Ja ^a,c   Moon, Phil Dong ^a,c   Myung, Noh Yil ^a,c   Kim, Min Cheol ^c   Kang, Tae Hee ^c   Lee, Kang Min ^b   Park, Rae Kil ^c   So, Hong seob ^c   Kim, Eun Cheol ^c   An, Nyeon Hyoung ^c   Um, Jae Young ^a   Kim, Hyung Min ^a   Hong, Seung Heon ^c  

^a Kyung Hee University   (South Korea)

^b Chonbuk National University   (South Korea)

^c Wonkwang University   (South Korea)

Author keywords

COX 2 inhibitor; Extracellular signal regulated protein kinase; Inflammatory allergic reaction; Passive cutaneous anaphylaxis

Indexed keywords

4 [5 (4 CHLOROPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOL 1 YL]BENZENESULFONAMIDE; ANTIINFLAMMATORY AGENT; COMPOUND 48-80; CYCLOOXYGENASE 2 INHIBITOR; HISTAMINE; IMMUNOGLOBULIN E; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ALLERGIC DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG INHIBITION; EAR SWELLING; HISTAMINE RELEASE; IMMUNOGLOBULIN PRODUCTION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY DISEASE; MALE; MAST CELL DEGRANULATION; NONHUMAN; PERITONEUM MAST CELL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; RAT; SKIN ANAPHYLAXIS; SWELLING; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; DISEASE MODELS, ANIMAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HISTAMINE; IMMUNOGLOBULIN E; INTERLEUKIN-6; MICE; NF-KAPPA B; PHOSPHORYLATION; PYRAZOLES; RATS; SULFONAMIDES; TUMOR NECROSIS FACTOR-ALPHA;

MURINAE; MUS; RATTUS;

EID: 34548473286     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2007.06.027     Document Type: Article

References (41)

1. Adwanikar H., Karin F., and Gereau R.W. Inflammation persistently enhances nocifensive behaviors mediated by spinal group I mGluRs through sustained ERK activation. Pain 111 (2004) 125-135
2. Artuc M., Hermes B., Steckelings U.M., Grutzkau A., and Henz B.M. Mast cells and their mediators in cutaneous wound healing-active participants or innocent bystanders?. Experimental Dermatology 8 (1999) 1-16
3. Bochenek G., Nizankowska E., Gielicz A., Swierczynska M., and Szczeklik A. Plasma 9alpha,11beta-PGF2, a PGD2 metabolite, as a sensitive marker of mast cell activation by allergen in bronchial asthma. Thorax 59 (2004) 459-464
4. Boehme S.B., Sullivan S.K., Crowe P.D., Santos M., Conlon P.J., Sriramarao P., and Bacon K.B. Activation of mitogen-activated protein kinase regulates eotaxin-induced eosinophil migration. Journal of Immunology 163 (1999) 1611-1618
5. Castano E., Bartrons R., and Gil J. Inhibition of cyclooxygenase-2 decreases DNA synthesis induced by platelet-derived growth factor in Swiss 3T3 fibroblasts. Journal of Pharmacology and Experimental Therapeutics 293 (2000) 509-513
6. Chang L., and Karin M. Mammalian MAP kinase signaling cascades. Nature 410 (2001) 37-40
7. Christman J.W., Sadikot R.T., and Blackwell T.S. The role of nuclear factor-K{green}B in pulmonary diseases. Chest 117 (2000) 1482-1487
8. Chun K.S., and Surh Y.J. Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention. Biochemical Pharmacology 68 (2004) 1089-1100
9. Conti P., Kempuraj D., Di Gioacchino M., Boucher W., Letourneau R., Kandere K., Barbacane R.C., Reale M., Felaco M., Frydas S., and Theoharides T.C. Interleukin-6 and mast cells. Allergy and Asthma Proceedings 23 (2002) 331-335
10. Dannhardt G., and Kiefer W. Cyclooxygenase inhibitors-current status and future prospects. European Journal of Medicinal Chemistry 36 (2001) 109-126
11. Duan W., Chan J.H., Wong C.H., Leung B.P., and Wong W.S. Anti-inflammatory effects of mitogen-activated protein kinase kinase inhibitor U0126 in an asthma mouse model. Journal of Immunology 172 11 (2004) 7053-7059
12. Gordon J.R., Burd P.R., and Galli S.J. Mast cells as a source of multifunctional cytokines. Immunology Today 11 (1990) 458-464
13. Hamelmann E., Tadeda K., Oshiba A., and Gelfand E.W. Role of IgE in the development of allergic airway inflammation and airway hyperresponsiveness. Allergy 54 (1999) 297-305
14. Hardy M.M., Seibert K., Manning P.T., Currie M.G., Woerner B.M., Edwards D., Koki A., and Tripp C.S. Cyclooxygenase 2-dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants. Arthritis and Rheumatism 46 (2002) 1789-1803
15. Hinz B., and Brune K. Cyclooxygenase-2-10 years later. Journal of Pharmacology and Experimental Therapeutics 300 (2002) 367-375
16. Iwasaki M., Saito K., Takemura M., Sekikawa K., Fujii H., Yamada Y., Wada H., Mizuta K., Seishima M., and Ito Y. TNF-alpha contributes to the development of allergic rhinitis in mice. Journal of Allergy and Clinical Immunology 112 (2003) 134-140
17. Jacob A.D., Cooney D., Pradhan M., and Coggeshall K.M. Convergence of signaling pathways on the activation of ERK in B cells. Journal of Biological Chemistry 26 (2002) 23420-23426
18. Jeong H.J., Chung H.S., Lee B.R., Kim S.J., Yoo S.J., Hong S.H., and Kim H.M. Expression of proinflammatory cytokines via HIF-1alpha and NF-kappaB activation on desferrioxamine-stimulated HMC-1 cells. Biochemical and Biophysical Research Communications 306 (2003) 805-811
19. Jippo-Kanemoto T., Kasugai T., Yamatodani A., Ushio H., Mochizuki T., Tohya K., Kimura M., Nishimura M., and Kitamura Y. Supernormal histamine release and normal cytotoxic activity of beige (Chediak-Higashi syndrome) rat mast cells with giant granules. International Archives of Allergy and Immunology 100 (1993) 99-106
20. Katayama S., Shionoya H., and Ohtake S. A new method for extraction of extravasated dye in the skin and the influence of fasting stress on passive cutaneous allergy in guinea pigs and rats. Microbiology and Immunology 22 (1978) 89-101
21. Kikuchi T., Ishida S., Kinoshita T., Sakuma S., Sugawara N., Yamashita T., and Koike K. IL-6 enhances IgE-dependent histamine release from human peripheral blood-derived cultured mast cells. Cytokine 20 (2002) 200-209
22. Kim S.H., Choi Y.K., Jeong H.J., Kang H.U., Moon G., Shin T.Y., and Kim H.M. Suppression of immunoglobulin E-mediated anaphylactic reaction by Alpini oxyphylla in rats. Immunopharmacology and Immunotoxicology 22 (2000) 267-277
23. Kumar A., Lnu S., Malya R., Barron D., Moore J., Corry D.B., and Boriek A.M. Mechanical stretch activates nuclear factor-K{green}B, activator protein-1, and mitogen-activated protein kinases in lung parenchyma: implications in asthma. FASEB Journal 17 (2003) 1800-1811
24. Langdon C., Kerr C., Tong L., Richards C.D., and Oncostatin M. Regulates eotaxin expression in fibroblasts and eosinophilic inflammation in C57BL/6 mice. Journal of Immunology 170 (2003) 548-555
25. Laporte J.C., Moore P.E., Baraldo S., Jouvin M.H., Church T.L., Schwartzman I.N., Panettieri Jr. R.A., Kinet J.P., and Shore S.A. Direct effects of interleukin-13 on signaling pathways for physiological responses in cultured human airway smooth muscle cells. American Journal of Respiratory Cell and Molecular Biology 164 (2001) 141-148
26. Lorentz A., Klopp I., Gebhardt T., Manns M.P., and Bischoff S.C. Role of activator protein 1, nuclear factor-K{green}B, and nuclear factor of activated T cells in IgE receptor-mediated cytokine expression in mature human mast cells. Journal of Allergy and Clinical Immunology 111 (2003) 1062-1068
27. Metcalfe D.D., Baram D., and Mekori Y.A. Mast cells. Physiological Reviews 77 (1997) 1033-1079
28. Miescher S.M., and Vogel M. Molecular aspects of allergy. Molecular Aspects of Medicine 23 (2002) 413-462
29. Moore P.E., Church T.L., Chism D.D., Panettieri Jr. R.A., and Shore S.A. IL-13 and IL-4 cause eotaxin release in human airway smooth muscle cells: a role for ERK. American Journal of Physiology. Lung Cellular and Molecular Physiology 282 (2002) 847-853
30. Nadler M.J., Matthews S.A., Turner H., and Kinet J.P. Signal transduction by the high-affinity immunoglobulin E receptor Fce{open}RI: coupling form to function. Advances in Immunology 76 (2000) 325-355
31. Oguma T., Asano K., Shiomi T., Fukunaga K., Suzuki Y., Nakamura M., Matsubara H., Sheldon H.K., Haley K.J., Lilly C.M., Drazen J.M., and Yamaguchi K. Cyclooxygenase-2 expression during allergic inflammation in guinea-pig lungs. American Journal of Respiratory and Critical Care Medicine 165 (2002) 382-386
32. O'Sullivan S., Dahlen S.E., Larsson K., Larsson B.M., Malmberg P., Kumlin M., and Palmberg L. Exposure of healthy volunteers to swine house dust increases formation of leukotrienes, prostaglandin D2, and bronchial responsiveness to methacholine. Thorax 53 (1998) 1041-1046
33. Panettieri Jr. R.A. Airway smooth muscle: an immunomodulatory cell. Journal of Allergy and Clinical Immunology 110 (2002) 269-274
34. Petersen C., Petersen S., Milas L., Lang F.F., and Tofilon P.J. Enhancement of intrinsic tumor cell radiosensitivity induced by a selective cyclooxygenase-2 inhibitor. Clinical Cancer Research 6 (2000) 2513-2520
35. Profita M., Sala A., Bonnano A., Riccobono L., Siena L., Melis M.R.Di., Giorgi R., Mirabella F., Gjomarkaj M., Bonsignore G., and Vignola A.M. Increased prostaglandin E2 concentrations and cyclooxygenase-2 expression in asthmatic subjects with sputum eosinophilia. Journal of Allergy and Clinical Immunology 112 (2003) 709-716
36. Shore P.A., Burkhalter A., and Cohn V.H. A method for fluorometric assay of histamine in tissues. Journal of Pharmacology and Experimental Therapeutics 127 (1959) 182-186
37. Smith W.L., Dewitt D.L., and Garavito R.M. Cyclooxygenases: structural, cellular and molecular biology. Annual Review of Biochemistry 69 (2000) 145-181
38. Tasaka K., Mio M., and Okamoto M. Intracellular calcium release induced by histamine releasers and its inhibition by some antiallergic drugs. Annals of Allergy 56 (1986) 464-469
39. 125I-fibrin deposition in IgE-dependent immediate hypersensitivity reactions in mouse skin. Demonstration of the role of mast cells using genetically mast cell-deficient mice locally reconstituted with cultured mast cells. Journal of Immunology 139 (1987) 2605-2614
40. Yang S.H., Whitmarsh A.J., Davis R.J., and Sharrocks A.D. Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1. EMBO Journal 17 (1998) 1740-1749
41. Zhu Z., Zheng T., Homer R.J., Kim Y.K., Chen N.Y., Cohn L., Hamid Q., and Elias J.A. Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation. Science 304 (2004) 1678-1682