A role of monocyte chemoattractant protein-4 (MCP-4)/CCL13 from chondrocytes in rheumatoid arthritis

FEBS Journal

Volumn 274, Issue 18, 2007, Pages 4904-4912

  Iwamoto, Takuji ^a,b   Okamoto, Hiroshi ^a   Kobayashi, Shu ^a,b   Ikari, Katsunori ^a   Toyama, Yoshiaki ^b   Tomatsu, Taisuke ^a   Kamatani, Naoyuki ^a   Momohara, Shigeki ^a  

^a TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

Chondrocytes; Extracellular signal regulated kinase (ERK); Monocyte chemoattractant protein 4 (MCP 4) CCL13; Rheumatoid arthritis

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; GAMMA INTERFERON; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 4; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CARTILAGE; CARTILAGE CELL; CELL ACTIVATION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN TISSUE; PATHOGENESIS; PHOSPHORYLATION; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SYNOVIOCYTE;

ARTHRITIS, RHEUMATOID; CELLS, CULTURED; CHONDROCYTES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; MONOCYTE CHEMOATTRACTANT PROTEINS; PHOSPHORYLATION; POLYMORPHISM, SINGLE NUCLEOTIDE; RNA, MESSENGER;

EID: 34548460833     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2007.06013.x     Document Type: Article

References (42)

1. Firestein GS (2003) Evolving concepts of rheumatoid arthritis. Nature 423, 356 361.
2. Feldmann M, Brennan FM Maini RN (1996) Rheumatoid arthritis. Cell 85, 307 310.
3. Charo IF Ransohoff RM (2006) The many roles of chemokines and chemokine receptors in inflammation. N Engl J Med 354, 610 621.
4. Sallusto F, Mackay CR Lanzavecchia A (2001) The role of chemokine receptors in primary, effector, and memory immune responses. Annu Rev Immunol 18, 593 620.
5. Luster AD (1998) Chemokines - chemotactic cytokines that mediate inflammation. N Engl J Med 338, 436 445.
6. Koch AE (2005) Chemokines and their receptors in rheumatoid arthritis: future targets? Arthritis Rheum 52, 710 721.
7. Garcia-Vicuna R, Gomez-Gaviro MV, Dominguez-Luis MJ, Pec MK, Gonzalez-Alvaro I, Alvaro-Gracia JM Diaz-Gonzalez F (2004) CC and CXC chemokine receptors mediate migration, proliferation, and matrix metalloproteinase production by fibroblast-like synoviocytes from rheumatoid arthritis patients. Arthritis Rheum 50, 3866 3877.
8. Haringman JJ, Ludikhuize J Tak PP (2004) Chemokines in joint disease: the key to inflammation? Ann Rheum Dis 63, 1186 1194.
9. Pulsatelli L, Dolzani P, Piacentini A, Silvestri T, Ruggeri R, Gualtieri G, Meliconi R Facchini A (1999) Chemokine production by human chondrocytes. J Rheumatol 26, 1992 2001.
10. Villiger PM, Terkeltaub R Lotz M (1992) Monocyte chemoattractant protein-1 (MCP-1) expression in human articular cartilage. Induction by peptide regulatory factors and differential effects of dexamethasone and retinoic acid. J Clin Invest 90, 488 496.
11. Iwamoto T, Okamoto H, Iikuni N, Takeuchi M, Toyama Y, Tomatsu T, Kamatani N Momohara S (2006) Monocyte chemoattractant protein-4 (MCP-4)/CCL13 is highly expressed in cartilage from patients with rheumatoid arthritis. Rheumatology (Oxford) 45, 421 424.
12. Garcia-Zepeda EA, Combadiere C, Rothenberg ME, Sarafi MN, Lavigne F, Hamid Q, Murphy PM Luster AD (1996) Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3. J Immunol 157, 5613 5626.
13. Uguccioni M, Loetscher P, Forssmann U, Dewald B, Li H, Lima SH, Li Y, Kreider B, Garotta G, Thelen M et al. (1996) Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin. J Exp Med 183, 2379 2384.
14. Lamkhioued B, Garcia-Zepeda EA, Abi-Younes S, Nakamura H, Jedrzkiewicz S, Wagner L, Renzi PM, Allakhverdi Z, Lilly C, Hamid Q et al. (2000) Monocyte chemoattractant protein (MCP)-4 expression in the airways of patients with asthma. Induction in epithelial cells and mononuclear cells by proinflammatory cytokines. Am J Respir Crit Care Med 162 (2 Part 1 723 732.
15. Kalayci O, Sonna LA, Woodruff PG, Camargo CA Jr., Luster AD Lilly CM (2004) Monocyte chemotactic protein-4 (MCP-4; CCL-13): a biomarker of asthma. J Asthma 41, 27 33.
16. Taha RA, Minshall EM, Miotto D, Shimbara A, Luster A, Hogg JC Hamid QA (1999) Eotaxin and monocyte chemotactic protein-4 mRNA expression in small airways of asthmatic and nonasthmatic individuals. J Allergy Clin Immunol 103 (3 Part 1 476 483.
17. Taha RA, Minshall EM, Leung DY, Boguniewicz M, Luster A, Muro S, Toda M Hamid QA (2000) Evidence for increased expression of eotaxin and monocyte chemotactic protein-4 in atopic dermatitis. J Allergy Clin Immunol 105, 1002 1007.
18. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS et al. (1998) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31, 315 324.
19. Okamoto H, Cujec TP, Okamoto M, Peterlin BM, Baba M Okamoto T (2000) Inhibition of the RNA-dependent transactivation and replication of human immunodeficiency virus type 1 by a fluoroquinoline derivative K-37. Virology 272, 402 408.
20. Matsuda Y, Singh G, Yamanaka H, Tanaka E, Urano W, Taniguchi A, Saito T, Hara M, Tomatsu T Kamatani N (2003) Validation of a Japanese version of the Stanford Health Assessment Questionnaire in 3,763 patients with rheumatoid arthritis. Arthritis Rheum 49, 784 788.
21. Ikari K, Kuwahara M, Nakamura T, Momohara S, Hara M, Yamanaka H, Tomatsu T Kamatani N (2005) Association between PADI4 and rheumatoid arthritis: a replication study. Arthritis Rheum 52, 3054 3057.
22. Kalayci O, Birben E, Wu L, Oguma T, Storm Van's Gravesande K, Subramaniam V, Sheldon HK, Silverman ES Lilly CM (2003) Monocyte chemoattractant protein-4 core promoter genetic variants: influence on YY-1 affinity and plasma levels. Am J Respir Cell Mol Biol 29, 750 756.
23. Altshuler D, Brooks LD, Chakravarti A, Collins FS, Daly MJ Donnelly PA (2005) Haplotype map of the human genome. Nature 437, 1299 1320.
24. Furutani Y, Nomura H, Notake M, Oyamada Y, Fukui T, Yamada M, Larsen CG, Oppenheim JJ Matsushima K (1989) Cloning and sequencing of the cDNA for human monocyte chemotactic and activating factor (MCAF). Biochem Biophys Res Commun 159, 249 255.
25. Berkhout TA, Sarau HM, Moores K, White JR, Elshourbagy N, Appelbaum E, Reape RJ, Brawner M, Makwana J, Foley JJ et al. (1997) Cloning, in vitro expression, and functional characterization of a novel human CC chemokine of the monocyte chemotactic protein (MCP) family (MCP-4) that binds and signals through the CC chemokine receptor 2B. J Biol Chem 272, 16404 16413.
26. Chakravorty SJ, Howie AJ, Girdlestone J, Gentle D Savage CO (2001) Potential role for monocyte chemotactic protein-4 (MCP-4) in monocyte/macrophage recruitment in acute renal inflammation. J Pathol 194, 239 246.
27. Hein H, Schluter C, Kulke R, Christophers E, Schroder JM Bartels J (1999) Genomic organization, sequence analysis and transcriptional regulation of the human MCP-4 chemokine gene (SCYA13) in dermal fibroblasts: a comparison to other eosinophilic beta-chemokines. Biochem Biophys Res Commun 255, 470 476.
28. Stellato C, Collins P, Ponath PD, Soler D, Newman W, La Rosa G, Li H, White J, Schwiebert LM, Bickel C et al. (1997) Production of the novel C-C chemokine MCP-4 by airway cells and comparison of its biological activity to other C-C chemokines. J Clin Invest 99, 926 936.
29. Feldmann M, Brennan FM Maini RN (1996) Role of cytokines in rheumatoid arthritis. Annu Rev Immunol 14, 397 440.
30. Henrotin YE, Zheng SX, Labasse AH, Deby GP, Crielaard JM Reginster JY (2000) Modulation of human chondrocyte metabolism by recombinant human interferon. Osteoarthritis Cartilage 8, 474 482.
31. Bunning RA Russell RG (1989) The effect of tumor necrosis factor alpha and gamma-interferon on the resorption of human articular cartilage and on the production of prostaglandin E and of caseinase activity by human articular chondrocytes. Arthritis Rheum 32, 780 784.
32. Andrews HJ, Bunning RA, Plumpton TA, Clark IM, Russell RG Cawston TE (1990) Inhibition of interleukin-1-induced collagenase production in human articular chondrocytes in vitro by recombinant human interferon-gamma. Arthritis Rheum 33, 1733 1738.
33. Lemmel EM, Brackertz D, Franke M, Gaus W, Hartl PW, Machalke K, Mielke H, Obert HJ, Peter HH, Sieper J et al. (1988) Results of a multicenter placebo-controlled double-blind randomized phase III clinical study of treatment of rheumatoid arthritis with recombinant interferon-gamma. Rheumatol Int 8, 87 93.
34. Sigidin YA, Loukina GV, Skurkovich B Skurkovich S (2001) Randomized, double-blind trial of anti-interferon-gamma antibodies in rheumatoid arthritis. Scand J Rheumatol 30, 203 207.
35. Lipsky PE, van der Heijde DM, St Clair EW, Furst DE, Breedveld FC, Kalden JR, Smolen JS, Weisman M, Emery P, Feldmann M et al. (2000) Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. N Engl J Med 343, 1594 1602.
36. Qu Z, Garcia CH, O'Rourke LM, Planck SR, Kohli M Rosenbaum JT (1994) Local proliferation of fibroblast-like synoviocytes contributes to synovial hyperplasia. Results of proliferating cell nuclear antigen/cyclin, c-myc, and nucleolar organizer region staining. Arthritis Rheum 37, 212 220.
37. Lacey D, Sampey A, Mitchell R, Bucala R, Santos L, Leech M Morand E (2003) Control of fibroblast-like synoviocyte proliferation by macrophage migration inhibitory factor. Arthritis Rheum 48, 103 109.
38. Inoue H, Takamori M, Nagata N, Nishikawa T, Oda H, Yamamoto S Koshihara Y (2001) An investigation of cell proliferation and soluble mediators induced by interleukin 1beta in human synovial fibroblasts: comparative response in osteoarthritis and rheumatoid arthritis. Inflamm Res 50, 65 72.
39. Schett G, Tohidast-Akrad M, Smolen JS, Schmid BJ, Steiner CW, Bitzan P, Zenz P, Redlich K, Xu Q Steiner G (2000) Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis. Arthritis Rheum 43, 2501 2512.
40. Youn J, Kim HY, Park JH, Hwang SH, Lee SY, Cho CS Lee SK (2002) Regulation of TNF-alpha-mediated hyperplasia through TNF receptors, TRAFs, and NF-kappaB in synoviocytes obtained from patients with rheumatoid arthritis. Immunol Lett 83, 85 93.
41. Rubinfeld H Seger R (2005) The ERK cascade: a prototype of MAPK signaling. Mol Biotechnol 31, 151 174.
42. Smalley KS (2003) A pivotal role for ERK in the oncogenic behaviour of malignant melanoma? Int J Cancer 104, 527 532.