Recombinant factor C competes against LBP to bind lipopolysaccharide and neutralizes the endotoxicity

Journal of Endotoxin Research

Volumn 13, Issue 3, 2007, Pages 150-157

  Li, Peng ^a   Ho, Bow ^a   Ding, Jeak Ling ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Endotoxin lipopolysaccharide (LPS); Factor C; LPS binding; LPS neutralization; LPS binding protein (LBP); p38; TNF

Indexed keywords

INTERLEUKIN 8; LIPOPOLYSACCHARIDE; LIPOPOLYSACCHARIDE BINDING PROTEIN; PEPTIDE; RECOMBINANT FACTOR C PROTEIN; SUSHI 1; SUSHI 2; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ACUTE PHASE PROTEIN; CARRIER PROTEIN; ENDOTOXIN; ENZYME PRECURSOR; FACTOR C; LIPOPOLYSACCHARIDE-BINDING PROTEIN; MEMBRANE PROTEIN; RECOMBINANT PROTEIN; SERINE PROTEINASE;

ARTICLE; BINDING AFFINITY; BINDING COMPETITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG BINDING; DRUG MECHANISM; DRUG SCREENING; ENZYME ACTIVITY; GENE AMPLIFICATION; HUMAN; HUMAN CELL; LIMULUS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; SEPTIC SHOCK; SIGNAL TRANSDUCTION; BINDING SITE; CELL CULTURE; CHEMISTRY; CYTOLOGY; GENETICS; ISOLATION AND PURIFICATION; MACROPHAGE; METABOLISM; MONOCYTE; PROTEIN TERTIARY STRUCTURE; SECRETION;

MEROSTOMATA;

ACUTE-PHASE PROTEINS; BINDING SITES; BINDING, COMPETITIVE; CARRIER PROTEINS; CELLS, CULTURED; ENDOTOXINS; ENZYME PRECURSORS; HUMANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MONOCYTES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 34548449911     PISSN: 09680519     EISSN: None     Source Type: Journal    
DOI: 10.1177/0968051907079573     Document Type: Article

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