Decorin gene transfer inhibited the expression of TGFβ1 and ECM in rat mesangial cells

European Journal of Medical Research

Volumn 12, Issue 8, 2007, Pages 360-368

  Wu, F ^a   Yao, H ^b   Bader, A ^c   Dong, F ^b   Zhu, F ^a   Wu, N ^b   Wang, B ^a   Li, Hong ^a   Brochmeyer, N H ^c   Altmeyer, P ^c  

^a ZHEJIANG UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; COLLAGEN TYPE 4; DECORIN; FIBRONECTIN; GLUCOSE; LAMININ; MESSENGER RNA; PEROXIDASE; RESTRICTION ENDONUCLEASE; TENASCIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL PROLIFERATION; CHO CELL; CONTROLLED STUDY; CULTURE MEDIUM; DIABETIC NEPHROPATHY; DOWN REGULATION; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENE SEQUENCE; GENE TRANSFER; IMMUNOHISTOCHEMISTRY; INHIBITION KINETICS; MESANGIUM CELL; NONHUMAN; PHARMACOLOGICAL BLOCKING; PROTEIN INTERACTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIRUS RECOMBINATION; WESTERN BLOTTING;

ADENOVIRIDAE; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; DECORIN; DNA, COMPLEMENTARY; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; GENE AMPLIFICATION; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; IMMUNOENZYME TECHNIQUES; MESANGIAL CELLS; PROTEOGLYCANS; RATS; RATS, SPRAGUE-DAWLEY; TRANSDUCTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA;

EID: 34548409610     PISSN: 09492321     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Singh LP, Green K, Alexander M, Bassly S, Crook ED. Hexosamines and TGF-1 use similar signaling pathways to mediate matrix protein synthesis in mesangial cells. Am J Physiol Renal Physiol, 2004, 286(2): F409-F416.
2. Lee HB, Yu MR, Yang Y, Jiang Z, Ha H. Reactive oxygen species-regulated signaling pathways in diabetic nephropathy. J Am Soc Nephrol, 2003, 14(8 Suppl. 3):S241-S245.
3. Abdel-Wahab N, Wicks SJ, Mason RM, Chantry A. Decorin suppresses transforming growth factor-induced espression of plasminogen activator inhibitor-1 in human mesangial cells through a medhanism that involves Ca2+-dependent phosphorylation of Smad2 at serine-240. Biochem J, 2002, 362(Pt 3):643-649.
4. Lee GT, Ha H, Jung M, Li H, Hong SW, Cha BS, Lee HC. Delayed treatment with lithospermate B attenuates experimental diabetic renal injury. J Am Soc Nephrol, 2003, 14(3):709-720.
5. Chen S, Jim B, Ziyadeh FN. Diabetic nephropathy and transforming growth factor-β: transforming our view of glomerulosclerosis and fibrosis build-up. Semin Nephrol, 2003, 23(6): 532-543.
6. 2+ in A431 carcinoma cells. J Biol Chem, 1998,273(6):3121-3124
7. Singh R, Alavi N, Singh AK, and Leehey DJ. Role of angiotensin II in glucose-induced inhibition of mesangial matrix degradation. Diabetes, 1999, 48(10): 2066-2073.
8. Mizuno S, Nakamura T. Suppressions of chronic glomerular injuries and TGF-β1 production by HGF in attenuation of murine diabetic nephropathy. Am J Physiol Renal Physiol, 2004,286(1): F134-F143.
9. Ziyadeh FN. Mediators of Diabetic Renal Disease: The case for TGF-β as the major mediator. J Am Soc Nephrol, 2004,15(Suppl 1):S55-S57.
10. Gore-Hyer E, Shegogue D, Markiewicz M, Lo S, Hazen-Martin D, Greene EL, Grotendorst G, et al. TGF-β and CTGF have overlapping and distinct fibrogenic effects on human renal cells. J Physiol Renal Physiol, 2002, 283(4): F707-F716.
11. Kim SI, Han DC, Lee HB. Lovastatin inhibits transforming growth factor-β1 expression in diabetic rat glomeruli and cultured rat mesangial cells. J Am Soc Nephrol, 2000, 11(1):80-87.
12. Lee HS, Moon KC, Song CY, Kim BC, Wang S, Hong HK. Glyeated albumin activates PAI-1 transcription through Smad DNA binding sites in mesangial cells. Am J Physiol, 2004, 287: F665-17672.
13. Abdel Wahab N and Mason RM. Modulation of neutral protease expression in human mesangial cells by hyperglycaemic culture. Bilchem J, 1996, 320(Pt 3):777-783.
14. Schnaper HW, Hayashida T, Hubchak SC, Poncelet AC. TGF- signal transduction and mesangial cell fibrogenesis. Am J Physiol, 2003, 284(2): F243-F252.
15. Yevdokimova N, Wahab NA, Mason RM. Thrombospondin-1 is the key activator of TGF-beta1 in human mesangial cells exposed to high glucose. J Am Soc Nephrol, 2001, 12(4):703-712.
16. Isaka Y, Brees DK, Ikegaya K, Kaneda Y, Imai E, Noble NA, Border WA. Gene therapy by skeletal muscle expression of decorin prevents fibrotic disezse in rat kidney. Nat Med, 1996, 2(4):418-423.
17. Al Haj Zen A, Lafont A, Durand E, Brasselet C, Lemarchand P, Godeau G, Gogly B. Effect of adenovirus-mediated overexpression of decorin on metalloproteinases, tissue inhibitors of metalloproteinses and cytokines secretion by human gingival fibroblasts. Matrix Biol, 2003, 22(3):251-258.
18. 2+ in A431 carcinoma cells. J Biol Chem, 1998, 273(6):3121-3124.
19. Kaname S, Uchida S, Ogata E, Kutokawa K. Autocrine secretion of transforming growth factor-beta in cultured rat mesangial cells. Kidney Int, 1992, 42(6):1319-1327.
20. Li H, Zheng FP, Ruan Y. Inhibitory effect of pioglitazone on TGFβ1 gene expression in renal cortex of diabetic rats. Chin J Endocrinol Metab, 2003, 19 (3) 238-239.
21. Fan WQ, Li H, Cai WM. Study on TGF-1 mRNA transcription of peripheral blood mononuclear cell in type 2 diabetic patients with nephropathy. Chin J Endocrinol Metab, 2001, 17 (6):341-343.
22. Douthwaite JA, Johnson TS, Haylor JL, Watson P, El Nahas AM. Effects of transforming growth factor-β on renal extracellular matrix components and their regulating proteins. J Am Soc Nephrol, 1999, 10(10): 2109-2119.
23. Poncelet AC, Schnaper HW. Regulation of human mesangial cell collagen expression by transforming growth factor-beta1. Am J Physiol, 1998, 275(3 Pt 2): F458-F466.
24. Wahab NA, Parker S, Sraer JD, Mason RM. The Decorin High Glucose Response Element and Mechanism of Its Activation in Human Mesangial Cells. J Am Soc Nephrol, 2000, 11(9):1607-1619.
25. Border WA, Noble NA, Yamamoto T, Harper JR, Yamaguchi Y, Pierschbacher MD, Ruoslahti E. Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease. Nature 1992; 360(6402):361-364.
26. Diamond JR, Levinson M, Kreisberg R, Ricardo SD. Increased expression of decorin in experimental hydronephrosis. Kidney Int, 1997, 51(4):1133-1139.
27. Vleming LJ, Baelde JJ, Westendorp RG, Daha MR, van Es LA, Bruijn JA. Progression of chronic renal disease in humans is associated with the deposition of basement membrane components and decorin in the interstitial extracellular matrix. Clin Nephrol, 1995, 44(4):211-219.
28. Mogyorosi A, Ziyadeh FN. Increased decorin mRNA in diabetic mouse kidney and in mesangial and tubular cells cultured in high glucose. Am J Physiol 1998, 275(5 Pt 2): F827-832.
29. Zhao J, Sime PJ, Bringas P Jr, Gauldie J, Warburton D. Adenovirus-mediated decorin gene transfer prevents TGFβ-induced inhibition of lung morphogenesis. Am J Physiol., 1999, 277(2 Pt 1):L412-422.
30. Wahab NA, Parker S, Sraer JD, Mason RM. The decorin high glucose response element and mechanism of its activation in human mesangial cells. J Am Soc Nephrol, 2000, 11(9): 1607-1619.
31. Schaefer L, Rashk I, Grone HJ, Schonherr E, Macakova K, Ugorcakova J, Budny S, Schaefer RM, Kresse H. Small proteoglycans in human diabetic nephropathy: Discrepancy between glomerular expression and protein accumulation of decorin, biglycan, lumican, and fibromodulin. The FASEB J, 2001, 15(3):559-561.
32. Border WA, Noble NA. Targeting TGF-β for treatment of disease. Nature Med, 1995, 1(10):1000-1001.
33. Ruoslahti E, Yamaguchi Y. Proteoglycans as modulators of growth factor activities. Cell, 1991, 64(5): 867-869.
34. Yoshida K, Suzuki Y, Honda E, Amemiya K, Nakatani T, Ebina M, Narumi K, Satoh K, Munakata H. Leucine-rich repeat region of decorin binds to filamin-A. Biochimie, 2002, 84(4):303-308.