Genetic polymorphisms of manganese-superoxide dismutase and glutathione-S-transferase in chronic alcoholic pancreatitis

Mutagenesis

Volumn 22, Issue 5, 2007, Pages 305-310

  Österreicher, Christoph H ^a   Schultheiss, Jürgen ^b   Wehler, Markus ^b   Homann, Nils ^c   Hellerbrand, Claus ^d   Künzli, Beat ^e   Friess, Helmut ^e   Seitz, Helmut K ^e   Stickel, Felix ^f  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c UNIVERSITY OF LÜBECK   (Germany)

^d UNIVERSITY OF REGENSBURG   (Germany)

^e UNIVERSITY OF HEIDELBERG   (Germany)

^f UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE; MANGANESE SUPEROXIDE DISMUTASE;

ADULT; ALCOHOLIC PANCREATITIS; ARTICLE; CHRONIC PANCREATITIS; CONTROLLED STUDY; ENZYME LOCALIZATION; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ADULT; FEMALE; GLUTATHIONE S-TRANSFERASE PI; HUMANS; MALE; MIDDLE AGED; PANCREATITIS, ALCOHOLIC; POLYMORPHISM, SINGLE NUCLEOTIDE; SUPEROXIDE DISMUTASE;

EID: 34548406916     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/gem017     Document Type: Article

References (38)

1. Apte, M. V. and Wilson, J. S. (2003) Alcohol-induced pancreatic injury. Best Pract. Res. Clin. Gastroenterol., 17, 593-612.
2. Whitcomb, D. C., Gorry, M. C., Preston, R. A. et al. (1996) Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat. Genet., 14, 141-145.
3. Witt, H., Luck, W., Hennies, H. C., Classen, M., Kage, A., Lass, U., Landt, O. and Becker, M. (2000) Mutations in the gene encoding the serine protease inhibitor, Kazal type I are associated with chronic pancreatitis. Nat. Genet., 25, 213-216.
4. Sharer, N., Schwarz, M., Malone, G., Howarth, A., Painter, J., Super, M. and Braganza, J. (1998) Mutations of the cystic fibrosis gene in patients with chronic pancreatitis. N. Engl. J. Med., 339, 645-652.
5. Verlaan, M., Te Morsche, R. H., Roelofs, H. M., Laheij, R. J., Jansen, J. B., Peters, W. H. and Drenth, J. P. (2004) Genetic polymorphisms in alcohol-metabolizing enzymes and chronic pancreatitis. Alcohol Alcohol., 39, 20-24.
6. Schneider, A., Barmada, M. M., Slivka, A., Martin, J. A. and Whitcomb, D. C. (2004) Analysis of tumor necrosis factor-alpha, transforming growth factor-beta, interleukin-10, and interferon-gamma polymorphisms in patients with alcoholic chronic pancreatitis. Alcohol, 32, 19-24.
7. Ockenga, J., Vogel, A., Teich, N., Keim, V., Manns, M. P. and Strassburg, C. P. (2003) UDP glucuronosyltransferase (UGT1A7) gene polymorphisms increase the risk of chronic pancreatitis and pancreatic cancer. Gastroenterology, 124, 1802-1808.
8. Beranek, H., Teich, N., Witt, H., Schulz, H. U., Mossner, J. and Keim, V. (2003) Analysis of tumor necrosis factor alpha and interleukin 10 promoter variants in patients with chronic pancreatitis. Eur. J. Gastroenterol. Hepatol., 15, 1223-1227.
9. Norton, I. D., Apte, M. V., Haber, P. S., McCaughan, G. W., Pirola, R. C. and Wilson, J. S. (1998) Cytochrome P450IIE1 is present in rat pancreas and is induced by chronic ethanol administration. Gut, 42, 426-430.
10. Aleynik, S. I., Leo, M. A., Aleynik, M. K. and Lieber, C. S. (1999) Alcohol-induced pancreatic oxidative process: protection by phospholipid repletion. Free Radic. Biol. Med., 26, 609-619.
11. Lerch, M. M., Albrecht, E., Ruthenburger, M., Mayerle, J., Halangk, W. and Kruger, B. (2003) Pathophysiology of alcohol-induced pancreatitis. Pancreas, 27, 291-296.
12. Hayes, J. D. and Strange, R. C. (2000) Glutathione S-transferase polymorphisms and their biological consequences. Pharmacology, 61, 154-166.
13. Ali-Osman, F., Akande, O., Antoun, G., Mao, J. X. and Buolamwini, J. (1997) Molecular cloning, characterisation and expression in Escherichia coli of full length cDNAs of three glutathione-S-transferase Pi gene variants. J. Biol. Chem., 272, 10004-10012.
14. Berhane, K., Widersten, M., Fangström, A., Kozarich, J. W. and Mannervik, B. (1994) Detoxication of base propenals and other α,β-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases. Proc. Natl. Acad. Sci. USA, 91, 1480-1484.
15. Stickel, F., Österreicher, C. H., Datz, C. et al. (2005) A functional polymorphism in the glutathione-S-transferase P1 gene determined the progression to cirrhosis in hereditary hemochromatosis but not in chronic hepatitis C. Arch. Int. Med., 165, 1835-1840.
16. Wallace, D. C. (1999) Mitochondrial disease in man and mouse. Science, 283, 1482-1488.
17. Wispé, J. R., Clark, J. C., Burhans, M. S., Kropp, K. E., Korfhagen, T. R. and Whitsett, J. A. (1989) Synthesis and processing of the precursor for human mangano-superoxide dismutase. Biochim. Biophys. Acta, 994, 30-36.
18. Shimoda-Matsubayashi, S., Mitsumine, H., Kobayashi, T. et al. (1996) Structural dimorphism in the mitochondrial targeting sequence in the human manganese superoxide dismutase gene. Biochem. Biophys. Res. Commun., 226, 561-565.
19. Sutton, A., Khoury, H., Prip-Buus, C., Nakagawa-Hattori, Y., Shimizu, Y. and Mizuno, Y. (2003) The Ala16Val genetic dimorphism modulates the import of human manganese superoxide dismutase into rat liver mitochondria. Pharmacogenetics, 13, 145-157.
20. Degoul, F., Sutton, A., Mansouri, A., Cepanec, C., Degott, C., Fromenty, B., Beaugrand, M., Valla, D. and Pessayre, D. (2001) Homozygosity for alanine in the mitochondrial targeting sequence of superoxide dismutase and risk for severe alcoholic liver disease. Gastroenterology, 120, 1468-1474.
21. Stewart, S. F., Leathart, J. B., Chen, Y. et al. (2002) Valine-alanine manganese superoxide dismutase polymorphism is not associated with alcohol-induced oxidative stress or liver fibrosis. Hepatology, 36, 1355-1360.
22. Rahman, S. H., Ibrahim, K., Larvin, M., Kingsnorth, A. and McMahon, M. J. (2004) Association of antioxidant enzyme gene polymorphism and glutathione status with severe acute pancreatitis. Gastroenterology, 126, 1312-1322.
23. Verlaan, M., Te Morsche, R. H., Roelofs, H. M., Laheij, R. J., Jansen, J. B., Peters, W. H. and Drenth, J. P. (2003) Glutathione S-transferase Mu null genotype affords protection against alcohol induced chronic pancreatitis. Am. J. Med. Genet., 120A, 34-39.
24. Burim, R. V., Canalle, R., Martinelli Ade, L. and Takahashi, C. S. (2004) Polymorphisms in glutathione S-transferases GSTM1, GSTT1 and GSTP1 and cytochromes P4502E1 and CYP1A1 and susceptibility to cirrhosis or pancreatitis in alcoholics. Mutagenesis, 19, 291-298.
25. Rahman, S. H., Nanny, C., Ibrahim, K., O'Reilly, D., Larvin, M., Kingsnorth, A. J. and McMahon, M. J. (2005) Genetic polymorphisms of GSTT1, GSTM1, GSTP1, MnSOD, and catalase in nonhereditary chronic pancreatitis: evidence of xenobiotic stress and impaired antioxidant capacity. Dig. Dis. Sci., 50, 1376-1383.
26. Layer, P., Yamamoto, H., Kalthoff, L., Clain, J. E., Bakken, L. J. and DiMagno, E. P. (1994) The different courses of early- and late-onset idiopathic and alcoholic chronic pancreatitis. Gastroenterology, 107, 1481-1487.
27. Löser, C., Mollgaard, A. and Fölsch, U. R. (1996) Faecal elastase 1: a novel, highly sensitive, and specific tubeless pancreatic function test. Gut, 39, 580-586.
28. Fischer, B., Hoh, S., Wehler, M., Hahn, E. G. and Schneider, H. T. (2001) Faecal elastase-1: lyophilization of stool samples prevents false low results in diarrhoea. Scand. J. Gastroenterol., 36, 771-774.
29. Homann, N., Stickel, F., König, I. R. et al. (2006) The alcohol dehydrogenase 1C*1 allele is a genetic marker for alcohol-associated cancer in heavy drinkers. Int. J. Cancer, 118, 1998-2002.
30. Henrion-Caude, A., Flamant, C., Roussey, M., Housset, C., Flahault, A., Fryer, A. A., Chadelat, K., Strange, R. C. and Clement, A. (2002) Liver disease in pediatric patients with cystic fibrosis is associated with glutathione S-transferase P1 polymorphism. Hepatology, 36, 913-917.
31. The International HapMap Project (2003) Nature, 426, 789-796.
32. Su, S. B., Motoo, Y., Xie, M. J., Mouri, H., Asayama, K. and Sawabu, N. (2002) Superoxide dismutase is induced during rat pancreatic acinar cell injury. Pancreas, 24, 146-152.
33. Kikuchi, Y., Shimosegawa, T., Moriizumi, S., Kimura, K., Satoh, A., Koizumi, M., Kato, I., Epstein, C. J. and Toyota, T. (1997) Transgenic copper/zinc-superoxide dismutase ameliorates caerulein-induced pancreatitis in mice. Biochem. Biophys. Res. Commun., 233, 177-181.
34. Chen, H., Li, X. and Epstein, P. N. (2005) MnSOD and catalase transgenes demonstrate that protection of islets from oxidative stress does not alter cytokine toxicity. Diabetes, 54, 1437-1446.
35. Bataller, R., North, K. E. and Brenner, D. A. (2003) Genetic polymorphisms and the progression of liver fibrosis: a critical appraisal. Hepatology, 37, 493-503.
36. Stickel, F. and Osterreicher, C. H. (2006) The role of genetic polymorphisms in alcoholic liver disease. Alcohol Alcohol., 41, 209-224.
37. Osterreicher, C., Stickel, F. and Brenner, D. A. (2007) Genomics of liver fibrosis and cirrhosis. Semin. Liver Dis., 27, 28-43.
38. Ioannidis, J. P., Ntzani, E. E., Trikalinos, T. A. and Contopoulos-Ioannidis, D. G. (2001) Replication validity of genetic association studies. Nat. Genet., 29, 306-309.