Discrimination of sheep susceptible and resistant to transmissible spongiform encephalopathies by an haplotype specific monoclonal antibody

Journal of Virological Methods

Volumn 145, Issue 2, 2007, Pages 169-172

  Bilheude, J M ^a   Brun, A ^b   Morel, N ^c   Diaz San Segundo F ^b   Lecroix, S ^a   Espinosa, J C ^b   Gonzalez L ^d   Steele, P ^e   Grassi, J ^c   Andreoletti O ^f   Torres, J M ^b  

^a R and D TSE ^*  (France)

^b Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria Consejo Superior de Investigaciones Científicas   (Spain)

^c Institut National de la Recherche Agronomique   (France)

^d VETERINARY LABORATORIES AGENCY   (United Kingdom)

^e MOREDUN RESEARCH INSTITUTE   (United Kingdom)

^f UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

ELISA test; Prion; PrP genotype discrimination; Scrapie susceptibility; TSE

Indexed keywords

MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 2A11; UNCLASSIFIED DRUG;

ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; BOVINE SPONGIFORM ENCEPHALOPATHY; BREEDING; DISEASE PREDISPOSITION; ENZYME IMMUNOASSAY; GENOTYPE; HAPLOTYPE; NONHUMAN; PRIORITY JOURNAL; VIRUS TRANSMISSION;

ANIMALS; ANTIBODIES, MONOCLONAL; CATTLE; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENETIC PREDISPOSITION TO DISEASE; GREAT BRITAIN; HAPLOTYPES; PRION DISEASES; PRIONS; SCRAPIE; SHEEP, DOMESTIC;

ANIMALIA; BOVINAE; OVIS; OVIS ARIES;

EID: 34548361973     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jviromet.2007.05.026     Document Type: Article

References (16)

1. Brun A., Castilla J., Ramirez M.A., Prager K., Parra B., Salguero F.J., Shiveral D., Sanchez C., Sanchez-Vizcaino J.M., Douglas A., and Torres J.M. Proteinase K enhanced immunoreactivity of the prion protein-specific monoclonal antibody 2A11. Neurosci. Res. 48 1 (2004) 75-83
2. Bujdoso, R., Burke, D.F., Thackray, A.M., 2005. Structural differences between allelic variants of the ovine prion protein revealed by molecular dynamics simulations. Proteins.
3. Clouscard C., Beaudry P., Elsen J.M., Milan D., Dussaucy M., Bounneau C., Schelcher F., Chatelain J., Launay J.M., and Laplanche J.L. Different allelic effects of the codons 136 and 171 of the prion protein gene in sheep with natural scrapie. J. Gen. Virol. 76 Pt 8 (1995) 2097-2101
4. Feraudet C., Morel N., Simon S., Volland H., Frobert Y., Creminon C., Vilette D., Lehmann S., and Grassi J. Screening of 145 anti-PrP monoclonal antibodies for their capacity to inhibit PrPSc replication in infected cells. J. Biol. Chem. 280 12 (2005) 11247-11258
5. Hunter N., Goldmann W., Smith G., and Hope J. The association of a codon 136 PrP gene variant with the occurrence of natural scrapie. Arch. Virol. 137 1-2 (1994) 171-177
6. Hunter N., Foster J.D., Goldmann W., Stear M.J., Hope J., and Bostock C. Natural scrapie in a closed flock of Cheviot sheep occurs only in specific PrP genotypes. Arch. Virol. 141 5 (1996) 809-824
7. Hunter N., Goldmann W., Foster J.D., Cairns D., and Smith G. Natural scrapie and PrP genotype: case-control studies in British sheep. Vet. Rec. 141 6 (1997) 137-140
8. Hunter N., Moore L., Hosie B.D., Dingwall W.S., and Greig A. Association between natural scrapie and PrP genotype in a flock of Suffolk sheep in Scotland. Vet. Rec. 140 3 (1997) 59-63
9. Krasemann S., Groschup M., Hunsmann G., and Bodemer W. Induction of antibodies against human prion proteins (PrP) by DNA-mediated immunization of PrP0/0 mice. J. Immunol. Methods 199 2 (1996) 109-118
10. Krasemann S., Jurgens T., and Bodemer W. Generation of monoclonal antibodies against prion proteins with an unconventional nucleic acid-based immunization strategy. J. Biotechnol. 73 2-3 (1999) 119-129
11. Luhken G., Buschmann A., Brandt H., Eiden M., Groschup M.H., and Erhardt G. Epidemiological and genetical differences between classical and atypical scrapie cases. Vet. Res. 38 1 (2007) 65-80
12. Moudjou M., Treguer E., Rezaei H., Sabuncu E., Neuendorf E., Groschup M.H., Grosclaude J., and Laude H. Glycan-controlled epitopes of prion protein include a major determinant of susceptibility to sheep scrapie. J. Virol. 78 17 (2004) 9270-9276
13. Prusiner S.B., McKinley M.P., Bowman K.A., Bolton D.C., Bendheim P.E., Groth D.F., and Glenner G.G. Scrapie prions aggregate to form amyloid-like birefringent rods. Cell 35 2 Pt 1 (1983) 349-358
14. Saunders G.C., Cawthraw S., Mountjoy S.J., Hope J., and Windl O. PrP genotypes of atypical scrapie cases in Great Britain. J. Gen. Virol. 87 Pt 11 (2006) 3141-3149
15. Thackray A.M., Fitzmaurice T.J., Hopkins L., and Bujdoso R. Ovine plasma prion protein levels show genotypic variation detected by C-terminal epitopes not exposed in cell-surface PrPC. Biochem. J. 400 2 (2006) 349-358
16. Wuthrich K., and Riek R. Three-dimensional structures of prion proteins. Adv. Protein Chem. 57 (2001) 55-82