Coactivation of Janus tyrosine kinase (Jak)1 positively modulates prolactin-Jak2 signaling in breast cancer: Recruitment of ERK and signal transducer and activator of transcription (Stat)3 and enhancement of Akt and Stat5a/b pathways

Molecular Endocrinology

Volumn 21, Issue 9, 2007, Pages 2218-2232

  Neilson, Lynn M ^a,b   Zhu, Jianquong ^a   Xie, Jianwu ^a   Malabarba, M Grazia ^c,d   Sakamoto, Kazuhito ^e   Wagner, Kay Uwe ^e   Kirken, Robert A ^f   Rui, Hallgeir ^a,g  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b GEORGETOWN UNIVERSITY   (United States)

^c FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

^e UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^f UNIVERSITY OF TEXAS AT EL PASO   (United States)

^g THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

JANUS KINASE 1; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE; PROLACTIN; PROLACTIN RECEPTOR; PROTEIN KINASE B; STAT3 PROTEIN; STAT5A PROTEIN; STAT5B PROTEIN;

ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

BREAST NEOPLASMS; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HUMANS; JANUS KINASE 1; JANUS KINASE 2; PROLACTIN; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STAT5 TRANSCRIPTION FACTOR;

EID: 34548348216     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2007-0173     Document Type: Article

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