Expression of gustducin overlaps with that of type III IP3 receptor in taste buds of the rat soft palate

Chemical Senses

Volumn 32, Issue 7, 2007, Pages 689-696

  Miura, Hirohito ^a   Nakayama, Ayumi ^a   Shindo, Yoichiro ^b   Kusakabe, Yuko ^c   Tomonari, Hiroshi ^a   Harada, Shuitsu ^a  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b ASAHI BREWERIES LTD   (Japan)

^c NATIONAL FOOD RESEARCH INSTITUTE   (Japan)

Author keywords

T1r 3; T2rs; Taste bud; Trpm5; Whole mount immunohistochemistry

Indexed keywords

CELL PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUSTDUCIN; TYPE III IP3 RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BITTER TASTE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SOFT PALATE; SWEETNESS; TASTE BUD; TASTE DISCRIMINATION; TONGUE; WESTERN BLOTTING;

ANIMALS; ANTIBODY SPECIFICITY; BLOTTING, WESTERN; CELL COUNT; CYTOPLASM; EPITHELIAL CELLS; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MALE; PALATE, SOFT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; TASTE BUDS; TONGUE; TRANSDUCIN; TRPM CATION CHANNELS;

RATTUS;

EID: 34548327203     PISSN: 0379864X     EISSN: 14643553     Source Type: Journal    
DOI: 10.1093/chemse/bjm036     Document Type: Article

References (26)

1. Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba JP, Zuker CS. 2000. A novel family of mammalian taste receptors. Cell. 100:693-702.
2. Belecky TL, Smith DV. 1990. Postnatal development of palatal and laryngeal taste buds in the hamster. J Comp Neurol. 293:646-654.
3. Bigiani A, Crietiani R, Fieni F, Ghiaroni V, Bagnoli P, Pietra P. 2002. Postnatal development of membrane excitability in taste cells of the mouse vallate papilla. J Neurosci. 22:493-504.
4. Boughter JD Jr, Pumplin DW, Yu C, Christy RC, Smith DV. 1997. Differential expression of alpha-gustducin in taste bud populations of the rat and hamster. J Neurosci. 17:2852-2858.
5. Clapp TR, Stone LM, Margolskee RF, Kinnamon SC. 2001. Immunocytochemical evidence for co-expression of type III IP3 receptor with signaling components of bitter taste transduction. BMC Neurosci. 2:6.
6. Glendinning JI, Bloom LD, Onishi M, Zheng KH, Damak S, Margolskee RF, Spector AC. 2005. Contribution of alpha-gustducin to taste-guided licking responses of mice. Chem Senses. 30:299-316.
7. Harada S. 1992. Effects of transection of the greater superficial petrosal and the chorda tympani nerves on conditioned taste aversion to sucrose in the hamster. Jpn J Oral Biol. 34:690-700.
8. Harada S, Smith DV. 1992. Gustatory sensitivities of the hamster's soft palate. Chem Senses. 17:37-51.
9. Harada S, Yamaguchi K, Kanemaru N, Kasahara Y. 2000. Maturation of taste buds on the soft palate of the postnatal rat. Physiol Behav. 68:333-339.
10. Harada S, Yamamoto T, Yamaguchi K, Kasahara Y. 1997. Different characteristics of gustatory responses between the greater superficial petrosal and chorda tympani nerves in the rat. Chem Senses. 22:133-140.
11. He W, Yasumatsu K, Varadarajan V, Yamada A, Lem J, Ninomiya Y, Margolskee RF, Damak S. 2004. Umami taste responses are mediated by alpha-transducin and alpha-gustducin. J Neurosci. 24:7674-7680.
12. Jayaraman T, Marks AR. 1997. T cells deficient in inositol 1,2,5-triphosphate receptor are resistant to apoptosis. Mol Cell Biol. 17:3005-3012.
13. Kim M-R, Kusakabe Y, Miura H, Shindo Y, Ninomiya Y, Hino A. 2003. Regional expression patterns of taste receptors and gustducin in the mouse tongue. Biochem Biophys Res Commun. 312:500-506.
14. Krimm RF, Nejad MS, Smith JC, Miller IJ Jr, Beidler LM. 1987. The effect of bilateral sectioning of the chorda tympani and the greater superficial petrosal nerves on the sweet taste in the rat. Physiol Behav. 41:495-501.
15. Matsunami H, Montmayeur J-P, Buck LB. 2000. A family of candidate taste receptors in human and mouse. Nature. 404:601-604.
16. Max M, Shanker YG, Huang L, Rong M, Liu Z, Campagne F, Weinstein H, Damak S, Margolskee RF. 2001. Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac. Nat Genet. 28:58-63.
17. Miyoshi MA, Abe K, Emori Y. 2001. IP(3) receptor type 3 and PLCbeta2 are co-expressed with taste receptors T1R and T2R in rat taste bud cells. Chem Senses. 26:259-265.
18. Mueller KL, Hoon MA, Erlenbach I, Chandrashekar J, Zuker CS, Ryba NJ. 2005. The receptors and coding logic for bitter taste. Nature. 434: 225-229.
19. Nejad MS. 1986. The neural activities of the greater superficial petrosal nerve of the rat in response to chemical stimulation of the palate. Chem Senses. 11:283-293.
20. Ozdener H, Yee KK, Cao J, Brand JG, Teeter JH, Rawson NE. 2006. Characterization and long-term maintenance of rat taste cells in culture. Chem Senses. 31:279-290.
21. Perez CA, Huang L, Rong M, Kozak JA, Preuss AK, Zhang H, Max M, Margolskee RF. 2002. A transient receptor potential channel expressed in taste receptor cells. Nat Neurosci. 5:1169-1176.
22. Ruiz CJ, Wray K, Delay E, Margolskee RF, Kinnamon SC. 2003. Behavioral evidence for a role of alpha-gustducin in glutamate taste. Chem Senses. 28:573-579.
23. Sako N, Harada S, Yamamoto T. 2000. Gustatory information of umami substances in three major taste nerves: Physiol Behav. 71:193-198.
24. Stone LM, Barrows J, Finger TE, Kinnamon SC. 2007. Expression of T1Rs and gustducin in palatal taste buds of mice. Chem Senses. 32:255-262.
25. Wong GT, Gannon KS, Margolskee RF. 1996. Transduction of bitter and sweet taste by gustducin. Nature. 381:796-800.
26. Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ. 2003. Coding of sweet, bitter, and umami tastes: Different receptor cells sharing similar signaling pathways. Cell. 112: 293-301.