Heterozygous tx mice have an increased sensitivity to copper loading: Implications for Wilson's disease carriers

BioMetals

Volumn 20, Issue 5, 2007, Pages 751-757

  Cheah, Daphne M Y ^a   Deal, Yolanda J ^b   Wright, Paul F A ^c   Buck, Nicole E ^a   Chow, Chung Wo ^a,d   Mercer, Julian F B ^b   Allen, Katrina J ^a,d  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b DEAKIN UNIVERSITY   (Australia)

^c RMIT UNIVERSITY   (Australia)

^d ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

Atp7b; Brain; Chronic copper exposure; Liver; tx mouse; Wilson's disease; Wilson's disease carriers

Indexed keywords

CERULOPLASMIN; COPPER; DRINKING WATER; OXIDOREDUCTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; BODY REGIONS; CERULOPLASMIN BLOOD LEVEL; CONTROLLED STUDY; DISEASE CARRIER; ENZYME ACTIVITY; HETEROZYGOSITY; LIVER HISTOLOGY; MOUSE; NONHUMAN; WILSON DISEASE;

ADENOSINE TRIPHOSPHATASES; ANIMALS; CATION TRANSPORT PROTEINS; COPPER; DISEASE MODELS, ANIMAL; FEMALE; HEPATOLENTICULAR DEGENERATION; HETEROZYGOTE DETECTION; MALE; MICE; MUTATION, MISSENSE;

MUS;

EID: 34548320831     PISSN: 09660844     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10534-006-9038-7     Document Type: Article

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