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Volumn 72, Issue 3, 2007, Pages 536-544

The impact of hypoxic treatment on the expression of phosphoglycerate kinase and the cytotoxicity of troxacitabine and gemcitabine

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYLOXALLYL GLYCINE; DNA; GEMCITABINE; GLYCINE DERIVATIVE; PHOSPHOGLYCERATE KINASE; TROXACITABINE; UNCLASSIFIED DRUG;

EID: 34548313707     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.106.033472     Document Type: Article
Times cited : (11)

References (33)
  • 1
    • 5044225419 scopus 로고    scopus 로고
    • Determinants of sensitivity and resistance to gemcitabine: The roles of human equilibrative nucleoside transporter 1 and deoxycytidine kinase in non-small cell lung cancer
    • Achiwa H, Oguri T, Sato S, Maeda H, Niimi T, and Ueda R (2004) Determinants of sensitivity and resistance to gemcitabine: the roles of human equilibrative nucleoside transporter 1 and deoxycytidine kinase in non-small cell lung cancer. Cancer Sci 95:753-757.
    • (2004) Cancer Sci , vol.95 , pp. 753-757
    • Achiwa, H.1    Oguri, T.2    Sato, S.3    Maeda, H.4    Niimi, T.5    Ueda, R.6
  • 2
    • 2942590732 scopus 로고    scopus 로고
    • Exploiting tumour hypoxia in cancer treatment
    • Brown JM and Wilson WR (2004) Exploiting tumour hypoxia in cancer treatment. Nat Rev Cancer 4:437-447.
    • (2004) Nat Rev Cancer , vol.4 , pp. 437-447
    • Brown, J.M.1    Wilson, W.R.2
  • 4
    • 0345686721 scopus 로고    scopus 로고
    • Chen G, Gharib TG, Wang H, Huang CC, Kuick R, Thomas DG, Shedden KA, Misek DE, Taylor JM, Giordano TJ, Kardia SL, Iannettoni MD, Yee J, Hogg PJ, Orringer MB, Hanash SM, and Beer DG (2003) Protein profiles associated with survival in lung adenocarcinoma Proc Natl Acad Sci U S A 100:13537-13542.
    • Chen G, Gharib TG, Wang H, Huang CC, Kuick R, Thomas DG, Shedden KA, Misek DE, Taylor JM, Giordano TJ, Kardia SL, Iannettoni MD, Yee J, Hogg PJ, Orringer MB, Hanash SM, and Beer DG (2003) Protein profiles associated with survival in lung adenocarcinoma Proc Natl Acad Sci U S A 100:13537-13542.
  • 5
    • 0034613195 scopus 로고    scopus 로고
    • A novel action of human apurinic/apyrimidinic endonuclease: Excision of L-configuration deoxyribonucleoside analogs from the 3′ termini of DNA
    • Chou KM, Kukhanova M, and Cheng YC (2000) A novel action of human apurinic/apyrimidinic endonuclease: excision of L-configuration deoxyribonucleoside analogs from the 3′ termini of DNA. J Biol Chem 275:31009-31015.
    • (2000) J Biol Chem , vol.275 , pp. 31009-31015
    • Chou, K.M.1    Kukhanova, M.2    Cheng, Y.C.3
  • 6
    • 1642603477 scopus 로고    scopus 로고
    • Secretion of phosphoglycerate kinase from tumour cells is controlled by oxygen-sensing hydroxylases
    • Daly EB, Wind T, Jiang XM, Sun L, and Hogg PJ (2004) Secretion of phosphoglycerate kinase from tumour cells is controlled by oxygen-sensing hydroxylases. Biochim Biophys Acta 1691:17-22.
    • (2004) Biochim Biophys Acta , vol.1691 , pp. 17-22
    • Daly, E.B.1    Wind, T.2    Jiang, X.M.3    Sun, L.4    Hogg, P.J.5
  • 12
    • 0029836284 scopus 로고    scopus 로고
    • Uptake and metabolism of the new anticancer compound beta-L-(-)-dioxolane-cytidine in human prostate carcinoma DU-145 cells
    • Grove KL and Cheng YC (1996) Uptake and metabolism of the new anticancer compound beta-L-(-)-dioxolane-cytidine in human prostate carcinoma DU-145 cells. Cancer Res 56:4187-4191.
    • (1996) Cancer Res , vol.56 , pp. 4187-4191
    • Grove, K.L.1    Cheng, Y.C.2
  • 13
    • 0028982940 scopus 로고
    • Anticancer activity of beta-L-dioxolane-cytidine, a novel nucleoside analogue with the unnatural L configuration
    • Grove KL, Guo X, Liu SH, Gao Z, Chu CK, and Cheng YC (1995) Anticancer activity of beta-L-dioxolane-cytidine, a novel nucleoside analogue with the unnatural L configuration. Cancer Res 55:3008-3011.
    • (1995) Cancer Res , vol.55 , pp. 3008-3011
    • Grove, K.L.1    Guo, X.2    Liu, S.H.3    Gao, Z.4    Chu, C.K.5    Cheng, Y.C.6
  • 16
    • 33645680173 scopus 로고    scopus 로고
    • Overexpression and elevated serum levels of phosphoglycerate kinase 1 in pancreatic ductal adenocarcinoma
    • Hwang TL, Liang Y, Chien KY, and Yu JS (2006) Overexpression and elevated serum levels of phosphoglycerate kinase 1 in pancreatic ductal adenocarcinoma. Proteomics 6:2259-2272.
    • (2006) Proteomics , vol.6 , pp. 2259-2272
    • Hwang, T.L.1    Liang, Y.2    Chien, K.Y.3    Yu, J.S.4
  • 18
    • 30044450909 scopus 로고    scopus 로고
    • A comparison of the transportability, and its role in cytotoxicity, of clofarabine, cladribine, and fludarabine by recombinant human nucleoside transporters produced in three model expression systems
    • King KM, Damaraju VL, Vickers MF, Yao SY, Lang T, Tackaberry TE, Mowles DA, Ng AM, Young JD, and Cass CE (2006) A comparison of the transportability, and its role in cytotoxicity, of clofarabine, cladribine, and fludarabine by recombinant human nucleoside transporters produced in three model expression systems. Mol Pharmacol 69:346-353.
    • (2006) Mol Pharmacol , vol.69 , pp. 346-353
    • King, K.M.1    Damaraju, V.L.2    Vickers, M.F.3    Yao, S.Y.4    Lang, T.5    Tackaberry, T.E.6    Mowles, D.A.7    Ng, A.M.8    Young, J.D.9    Cass, C.E.10
  • 19
    • 1442302331 scopus 로고    scopus 로고
    • Mammalian nucleoside transporters
    • Kong W, Engel K, and Wang J (2004) Mammalian nucleoside transporters. Curr Drug Metab 5:63-84.
    • (2004) Curr Drug Metab , vol.5 , pp. 63-84
    • Kong, W.1    Engel, K.2    Wang, J.3
  • 21
    • 0037085269 scopus 로고    scopus 로고
    • Phosphorylation of pyrimidine deoxynucleoside analog diphosphates: Selective phosphorylation of L-nucleoside analog diphosphates by 3-phosphoglycerate kinase
    • Krishnan P, Fu Q, Lam W, Liou JY, Dutschman G, and Cheng YC (2002a) Phosphorylation of pyrimidine deoxynucleoside analog diphosphates: selective phosphorylation of L-nucleoside analog diphosphates by 3-phosphoglycerate kinase. J Biol Chem 277:5453-5459.
    • (2002) J Biol Chem , vol.277 , pp. 5453-5459
    • Krishnan, P.1    Fu, Q.2    Lam, W.3    Liou, J.Y.4    Dutschman, G.5    Cheng, Y.C.6
  • 22
    • 0037200016 scopus 로고    scopus 로고
    • Phosphorylation of pyrimidine L-deoxynucleoside analog diphosphates. Kinetics of phosphorylation and dephosphorylation of nucleoside analog diphosphates and triphosphates by 3-phosphoglycerate kinase
    • Krishnan P, Liou JY, and Cheng YC (2002b) Phosphorylation of pyrimidine L-deoxynucleoside analog diphosphates. Kinetics of phosphorylation and dephosphorylation of nucleoside analog diphosphates and triphosphates by 3-phosphoglycerate kinase. J Biol Chem 277:31593-31600.
    • (2002) J Biol Chem , vol.277 , pp. 31593-31600
    • Krishnan, P.1    Liou, J.Y.2    Cheng, Y.C.3
  • 23
    • 0141591803 scopus 로고    scopus 로고
    • Novel role of 3-phosphoglycerate kinase, a glycolytic enzyme, in the activation of L-nucleoside analogs, a new class of anticancer and antiviral agents
    • Krishnan P, Gullen EA, Lam W, Dutschman GE, Grill SP, and Cheng YC (2003) Novel role of 3-phosphoglycerate kinase, a glycolytic enzyme, in the activation of L-nucleoside analogs, a new class of anticancer and antiviral agents. J Biol Chem 278:36726-36732.
    • (2003) J Biol Chem , vol.278 , pp. 36726-36732
    • Krishnan, P.1    Gullen, E.A.2    Lam, W.3    Dutschman, G.E.4    Grill, S.P.5    Cheng, Y.C.6
  • 24
    • 0029088833 scopus 로고
    • L- and D-enantiomers of 2′,3′-dideoxycytidine 5′-triphosphate analogs as substrates for human DNA polymerases. Implications for the mechanism of toxicity
    • Kukhanova M, Liu SH, Mozzherin D, Lin TS, Chu CK, and Cheng YC (1995) L- and D-enantiomers of 2′,3′-dideoxycytidine 5′-triphosphate analogs as substrates for human DNA polymerases. Implications for the mechanism of toxicity. J Biol Chem 270:23055-23059.
    • (1995) J Biol Chem , vol.270 , pp. 23055-23059
    • Kukhanova, M.1    Liu, S.H.2    Mozzherin, D.3    Lin, T.S.4    Chu, C.K.5    Cheng, Y.C.6
  • 25
    • 33645820026 scopus 로고    scopus 로고
    • Apurinic/apyrimidinic endonuclease-1 protein level is associated with the cytotoxicity of L-configuration deoxycytidine analogs (troxacitabine and β-L-2′,3′-dideoxy-2′,3′-didehydro-5-fluorocytidine) but not D-configuration deoxycytidine analogs (gemcitabine and β-D-arabinofuranosylcytosine)
    • Lam W, Park SY, Leung CH, and Cheng YC (2006) Apurinic/apyrimidinic endonuclease-1 protein level is associated with the cytotoxicity of L-configuration deoxycytidine analogs (troxacitabine and β-L-2′,3′-dideoxy-2′,3′-didehydro-5-fluorocytidine) but not D-configuration deoxycytidine analogs (gemcitabine and β-D-arabinofuranosylcytosine). Mol Pharmacol 69:1607-1614.
    • (2006) Mol Pharmacol , vol.69 , pp. 1607-1614
    • Lam, W.1    Park, S.Y.2    Leung, C.H.3    Cheng, Y.C.4
  • 27
    • 0037086275 scopus 로고    scopus 로고
    • Characterization of human UMP/CMP kinase and its phosphorylation of D- and L-form deoxycytidine analogue monophosphates
    • Liou JY, Dutschman GE, Lam W, Jiang Z, and Cheng YC (2002) Characterization of human UMP/CMP kinase and its phosphorylation of D- and L-form deoxycytidine analogue monophosphates. Cancer Res 62:1624-1631.
    • (2002) Cancer Res , vol.62 , pp. 1624-1631
    • Liou, J.Y.1    Dutschman, G.E.2    Lam, W.3    Jiang, Z.4    Cheng, Y.C.5
  • 28
    • 33745792969 scopus 로고    scopus 로고
    • Expression of human equilibrative nucleoside transporter 1 (hENT1) and its correlation with gemcitabine uptake and cytotoxicity in mantle cell lymphoma
    • Marcé S, Molina-Arcas M, Villamor N, Casado FJ, Campo E, Pastor-Anglada M, and Colomer D (2006) Expression of human equilibrative nucleoside transporter 1 (hENT1) and its correlation with gemcitabine uptake and cytotoxicity in mantle cell lymphoma. Haematologica 91:895-902.
    • (2006) Haematologica , vol.91 , pp. 895-902
    • Marcé, S.1    Molina-Arcas, M.2    Villamor, N.3    Casado, F.J.4    Campo, E.5    Pastor-Anglada, M.6    Colomer, D.7
  • 29
    • 0032508691 scopus 로고    scopus 로고
    • Hypoxia-inducible mammalian gene expression analyzed in vivo at a TATA-driven promoter and at an initiator-driven promoter
    • Okino ST, Chichester CH, and Whitlock JP Jr. (1998) Hypoxia-inducible mammalian gene expression analyzed in vivo at a TATA-driven promoter and at an initiator-driven promoter. J Biol Chem 273:23837-23843.
    • (1998) J Biol Chem , vol.273 , pp. 23837-23843
    • Okino, S.T.1    Chichester, C.H.2    Whitlock Jr., J.P.3
  • 31
    • 31544467281 scopus 로고    scopus 로고
    • Recent advances in studies on biochemical and structural properties of equilibrative and concentrative nucleoside transporters
    • Podgorska M, Kocbuch K, and Pawelczyk T (2005) Recent advances in studies on biochemical and structural properties of equilibrative and concentrative nucleoside transporters. Acta Biochim Pol 52:749-758.
    • (2005) Acta Biochim Pol , vol.52 , pp. 749-758
    • Podgorska, M.1    Kocbuch, K.2    Pawelczyk, T.3
  • 32
    • 6044267987 scopus 로고    scopus 로고
    • The absence of human equilibrative nucleoside transporter 1 is associated with reduced survival in patients with gemcitabine-treated pancreas adenocarcinoma
    • Spratlin J, Sangha R, Glubrecht D, Dabbagh L, Young JD, Dumontet C, Cass C, Lai R, and Mackey JR (2004) The absence of human equilibrative nucleoside transporter 1 is associated with reduced survival in patients with gemcitabine-treated pancreas adenocarcinoma. Clin Cancer Res 10:6956-6961.
    • (2004) Clin Cancer Res , vol.10 , pp. 6956-6961
    • Spratlin, J.1    Sangha, R.2    Glubrecht, D.3    Dabbagh, L.4    Young, J.D.5    Dumontet, C.6    Cass, C.7    Lai, R.8    Mackey, J.R.9
  • 33
    • 28644439593 scopus 로고    scopus 로고
    • Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer
    • Zhang D, Tai LK, Wong LL, Chiu LL, Sethi SK, and Koay ES (2005) Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer. Mol Cell Proteomics 4:1686-1696.
    • (2005) Mol Cell Proteomics , vol.4 , pp. 1686-1696
    • Zhang, D.1    Tai, L.K.2    Wong, L.L.3    Chiu, L.L.4    Sethi, S.K.5    Koay, E.S.6


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