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Volumn 48, Issue 2-3, 2007, Pages 191-199

Improving islet transplantation by gene delivery of hepatocyte growth factor (HGF) and its downstream target, protein kinase B (PKB)/Akt

Author keywords

Akt; Diabetes; Gene therapy; Hepatocyte growth factor; Islet transplantation; Pancreatic beta cell; Protein kinase B

Indexed keywords

PROTEIN KINASE B; SCATTER FACTOR; SCATTER FACTOR RECEPTOR;

EID: 34548309341     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-007-0024-7     Document Type: Article
Times cited : (19)

References (57)
  • 9
    • 9644294263 scopus 로고    scopus 로고
    • Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus
    • Rother, K. I., & Harlan, D. M. (2004). Challenges facing islet transplantation for the treatment of type 1 diabetes mellitus. Journal of Clinical Investigation, 114, 877-883.
    • (2004) Journal of Clinical Investigation , vol.114 , pp. 877-883
    • Rother, K.I.1    Harlan, D.M.2
  • 11
    • 21044455869 scopus 로고    scopus 로고
    • Matsumoto, S., Okitsu, T., Iwanaga, Y., Noguchi, H., Nagata, H., Yonekawa, Y., Yamada, Y., Fukuda, K., Tsukiyama, K., Suzuki, H., Kawasaki, Y., Shimodaira, M., Matsuoka, K., Shibata, T., Kasai, Y., Maekawa, T., Shapiro, J., & Tanaka, K. (2005). Insulin independence after living-donor distal pancreatectomy and islet allotransplantation. Lancet, 365, 1642-1644.
    • Matsumoto, S., Okitsu, T., Iwanaga, Y., Noguchi, H., Nagata, H., Yonekawa, Y., Yamada, Y., Fukuda, K., Tsukiyama, K., Suzuki, H., Kawasaki, Y., Shimodaira, M., Matsuoka, K., Shibata, T., Kasai, Y., Maekawa, T., Shapiro, J., & Tanaka, K. (2005). Insulin independence after living-donor distal pancreatectomy and islet allotransplantation. Lancet, 365, 1642-1644.
  • 13
    • 0036706858 scopus 로고    scopus 로고
    • Alternatives to unmodified human islets for transplantation
    • Hayek, A., & Beattie, G. M. (2002). Alternatives to unmodified human islets for transplantation. Current Diabetes Reports, 2, 371-376.
    • (2002) Current Diabetes Reports , vol.2 , pp. 371-376
    • Hayek, A.1    Beattie, G.M.2
  • 15
    • 0034693753 scopus 로고    scopus 로고
    • Met receptor tyrosine kinase: Enhanced signaling through adapter proteins
    • Furge, K. A., Zhang, Y. W., & Vande Woude, G. F. (2000). Met receptor tyrosine kinase: Enhanced signaling through adapter proteins. Oncogene, 19, 5582-5589.
    • (2000) Oncogene , vol.19 , pp. 5582-5589
    • Furge, K.A.1    Zhang, Y.W.2    Vande Woude, G.F.3
  • 16
    • 0038026134 scopus 로고    scopus 로고
    • Roles of hepatocyte growth factor (HGF) activator and HGF activator inhibitor in the pericellular activation of HGF/scatter factor
    • Kataoka, H., Miyata, S., Uchinokura, S., & Itoh, H. (2003). Roles of hepatocyte growth factor (HGF) activator and HGF activator inhibitor in the pericellular activation of HGF/scatter factor. Cancer Metastasis Reviews, 22, 223-236.
    • (2003) Cancer Metastasis Reviews , vol.22 , pp. 223-236
    • Kataoka, H.1    Miyata, S.2    Uchinokura, S.3    Itoh, H.4
  • 18
    • 24644520998 scopus 로고    scopus 로고
    • Administration of control-released hepatocyte growth factor enhances the efficacy of skeletal myoblast transplantation in rat infarcted hearts by greatly increasing both quantity and quality of the graft
    • Tambara, K., Premaratne, G. U., Sakaguchi, G., Kanemitsu, N., Lin, X., Nakajima, H., Sakakibara, Y., Kimura, Y., Yamamoto, M., Tabata, Y., Ikeda, T., & Komeda, M. (2005). Administration of control-released hepatocyte growth factor enhances the efficacy of skeletal myoblast transplantation in rat infarcted hearts by greatly increasing both quantity and quality of the graft. Circulation, 112, 129-134.
    • (2005) Circulation , vol.112 , pp. 129-134
    • Tambara, K.1    Premaratne, G.U.2    Sakaguchi, G.3    Kanemitsu, N.4    Lin, X.5    Nakajima, H.6    Sakakibara, Y.7    Kimura, Y.8    Yamamoto, M.9    Tabata, Y.10    Ikeda, T.11    Komeda, M.12
  • 21
    • 0141813585 scopus 로고    scopus 로고
    • Hepatocyte growth factor prevents chronic allograft dysfunction in liver-transplanted rats
    • Tashiro, H., Fudaba, Y., Itoh, H., Mizunuma, K., Ohdan, H., Itamoto, T., & Asahara, T. (2003). Hepatocyte growth factor prevents chronic allograft dysfunction in liver-transplanted rats. Transplantation, 76, 761-765.
    • (2003) Transplantation , vol.76 , pp. 761-765
    • Tashiro, H.1    Fudaba, Y.2    Itoh, H.3    Mizunuma, K.4    Ohdan, H.5    Itamoto, T.6    Asahara, T.7
  • 22
    • 4444231732 scopus 로고    scopus 로고
    • Hepatocyte growth factor preserves graft-versus-leukemia effect and T-cell reconstitution after marrow transplantation
    • Imado, T., Iwasaki, T., Kataoka, Y., Kuroiwa, T., Hara, H., Fujimoto, J., & Sano, H. (2004). Hepatocyte growth factor preserves graft-versus-leukemia effect and T-cell reconstitution after marrow transplantation. Blood, 104, 1542-1549.
    • (2004) Blood , vol.104 , pp. 1542-1549
    • Imado, T.1    Iwasaki, T.2    Kataoka, Y.3    Kuroiwa, T.4    Hara, H.5    Fujimoto, J.6    Sano, H.7
  • 24
    • 0027261480 scopus 로고
    • Hepatocyte growth factor may function as a renotropic factor for regeneration in rats with acute renal injury
    • Igawa, T., Matsumoto, K., Kanda, S., Saito, Y., & Nakamura, T. (1993). Hepatocyte growth factor may function as a renotropic factor for regeneration in rats with acute renal injury. American Journal of Physiology, 265, F61-F69.
    • (1993) American Journal of Physiology , vol.265
    • Igawa, T.1    Matsumoto, K.2    Kanda, S.3    Saito, Y.4    Nakamura, T.5
  • 25
    • 0029821899 scopus 로고    scopus 로고
    • Vulnerability of islets in the immediate posttransplantation period. Dynamic changes in structure and function
    • Davalli, A. M., Scaglia, L., Zangen, D. H., Hollister, J., Bonner-Weir, S., & Weir, G. C. (1996). Vulnerability of islets in the immediate posttransplantation period. Dynamic changes in structure and function. Diabetes, 45, 1161-1167.
    • (1996) Diabetes , vol.45 , pp. 1161-1167
    • Davalli, A.M.1    Scaglia, L.2    Zangen, D.H.3    Hollister, J.4    Bonner-Weir, S.5    Weir, G.C.6
  • 27
    • 0030015057 scopus 로고    scopus 로고
    • A role for hepatocyte growth factor/scatter factor in fetal mesenchyme-induced pancreatic beta-cell growth
    • Otonkoski, T., Cirulli, V., Beattie, M., Mally, M. I., Soto, G., Rubin, J. S., & Hayek, A. (1996). A role for hepatocyte growth factor/scatter factor in fetal mesenchyme-induced pancreatic beta-cell growth. Endocrinology, 137, 3131-3139.
    • (1996) Endocrinology , vol.137 , pp. 3131-3139
    • Otonkoski, T.1    Cirulli, V.2    Beattie, M.3    Mally, M.I.4    Soto, G.5    Rubin, J.S.6    Hayek, A.7
  • 28
    • 0029795884 scopus 로고    scopus 로고
    • Regulation of proliferation and differentiation of human fetal pancreatic islet cells by extracellular matrix, hepatocyte growth factor, and cell-cell contact
    • Beattie, G. M., Rubin J. S., Mally, M. I., Otonkoski, T., & Hayek, A. (1996). Regulation of proliferation and differentiation of human fetal pancreatic islet cells by extracellular matrix, hepatocyte growth factor, and cell-cell contact. Diabetes, 45, 1223-1228.
    • (1996) Diabetes , vol.45 , pp. 1223-1228
    • Beattie, G.M.1    Rubin, J.S.2    Mally, M.I.3    Otonkoski, T.4    Hayek, A.5
  • 29
    • 0028799972 scopus 로고
    • Growth factor/matrix-induced proliferation of human adult beta-cells
    • Hayek, A., Beattie, G. M., Cirulli, V., Lopez, A. D., Ricordi, C., & Rubin, J. S. (1995). Growth factor/matrix-induced proliferation of human adult beta-cells. Diabetes, 44, 1458-1460.
    • (1995) Diabetes , vol.44 , pp. 1458-1460
    • Hayek, A.1    Beattie, G.M.2    Cirulli, V.3    Lopez, A.D.4    Ricordi, C.5    Rubin, J.S.6
  • 30
    • 0028284507 scopus 로고
    • Hepatocyte growth factor/scatter factor has insulinotropic activity in human fetal pancreatic cells
    • Otonkoski, T., Beattie, G. M., Rubin, J. S., Lopez, A. D., Baird, A., & Hayek, A. (1994). Hepatocyte growth factor/scatter factor has insulinotropic activity in human fetal pancreatic cells. Diabetes, 43, 947-953.
    • (1994) Diabetes , vol.43 , pp. 947-953
    • Otonkoski, T.1    Beattie, G.M.2    Rubin, J.S.3    Lopez, A.D.4    Baird, A.5    Hayek, A.6
  • 32
    • 0033954474 scopus 로고    scopus 로고
    • Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia
    • Garcia-Ocana, A., Takane, K. K., Syed, M. A., Philbrick, W. M., Vasavada, R. C., & Stewart, A. F. (2000). Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia. Journal of Biological Chemistry, 275, 1226-1232.
    • (2000) Journal of Biological Chemistry , vol.275 , pp. 1226-1232
    • Garcia-Ocana, A.1    Takane, K.K.2    Syed, M.A.3    Philbrick, W.M.4    Vasavada, R.C.5    Stewart, A.F.6
  • 33
    • 0035650568 scopus 로고    scopus 로고
    • Transgenic overexpression of hepatocyte growth factor in the beta-cell markedly improves islet function and islet transplant outcomes in mice
    • Garcia-Ocana, A., Vasavada, R. C., Cebrian, A., Reddy, V., Takane, K. K., Lopez-Talavera, J. C., & Stewart, A. F. (2001). Transgenic overexpression of hepatocyte growth factor in the beta-cell markedly improves islet function and islet transplant outcomes in mice. Diabetes, 50, 2752-2762.
    • (2001) Diabetes , vol.50 , pp. 2752-2762
    • Garcia-Ocana, A.1    Vasavada, R.C.2    Cebrian, A.3    Reddy, V.4    Takane, K.K.5    Lopez-Talavera, J.C.6    Stewart, A.F.7
  • 34
    • 0037414812 scopus 로고    scopus 로고
    • Adenovirus-mediated hepatocyte growth factor expression in mouse islets improves pancreatic islet transplant performance and reduces beta cell death
    • Garcia-Ocana, A., Takane, K. K., Reddy, V. T., Lopez-Talavera, J. -C., Vasavada, R. C., & Stewart, A. F. (2003). Adenovirus-mediated hepatocyte growth factor expression in mouse islets improves pancreatic islet transplant performance and reduces beta cell death. Journal of Biological Chemistry, 278, 343-351.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 343-351
    • Garcia-Ocana, A.1    Takane, K.K.2    Reddy, V.T.3    Lopez-Talavera, J.-C.4    Vasavada, R.C.5    Stewart, A.F.6
  • 35
    • 0036238957 scopus 로고    scopus 로고
    • Hepatocyte growth factor stimulates proliferation of pancreatic beta-cells particularly in the presence of subphysiological glucose concentrations
    • Gahr, S., Merger, M., Bollheimer, L. C., Hammerschmied, C. G., Scholmerich, J., & Hugl, S. R. (2002). Hepatocyte growth factor stimulates proliferation of pancreatic beta-cells particularly in the presence of subphysiological glucose concentrations. Journal of Molecular Endocrinology, 28, 99-110.
    • (2002) Journal of Molecular Endocrinology , vol.28 , pp. 99-110
    • Gahr, S.1    Merger, M.2    Bollheimer, L.C.3    Hammerschmied, C.G.4    Scholmerich, J.5    Hugl, S.R.6
  • 36
    • 0029815929 scopus 로고    scopus 로고
    • Formation of insulin-producing cells from pancreatic acinar AR42J cells by hepatocyte growth factor
    • Mashima, H., Shibata, H., Mine, T., & Kojima, I. (1996). Formation of insulin-producing cells from pancreatic acinar AR42J cells by hepatocyte growth factor. Endocrinology, 137, 3969-3976.
    • (1996) Endocrinology , vol.137 , pp. 3969-3976
    • Mashima, H.1    Shibata, H.2    Mine, T.3    Kojima, I.4
  • 37
    • 12344260874 scopus 로고    scopus 로고
    • Hepatocyte growth factor regulates proliferation and differentiation of epithelial monolayers derived from islets of postnatal rat pancreas
    • Wang, R., Yashpal, N., Bacchus, F., & Li, J. (2004). Hepatocyte growth factor regulates proliferation and differentiation of epithelial monolayers derived from islets of postnatal rat pancreas. Journal of Endocrinology, 183, 163-171.
    • (2004) Journal of Endocrinology , vol.183 , pp. 163-171
    • Wang, R.1    Yashpal, N.2    Bacchus, F.3    Li, J.4
  • 38
    • 0031985941 scopus 로고    scopus 로고
    • Hepatocyte growth factor up-regulates SGLT1 and GLUT5 gene expression after massive small bowel resection
    • Kato, Y., Yu, D., & Schwartz, M. Z. (1998). Hepatocyte growth factor up-regulates SGLT1 and GLUT5 gene expression after massive small bowel resection. Journal of Pediatric Surgery, 33, 13-15.
    • (1998) Journal of Pediatric Surgery , vol.33 , pp. 13-15
    • Kato, Y.1    Yu, D.2    Schwartz, M.Z.3
  • 39
    • 0034719348 scopus 로고    scopus 로고
    • Hepatocyte growth factor is essential for amelioration of hyperglycemia in streptozotocin-induced diabetic mice receiving a marginal mass of intrahepatic islet grafts
    • Nakano, M., Yasunami, Y., Maki, T., Kodama, S., Ikehara, Y., Nakamura, T., Tanaka, M., & Ikeda, S. (2000). Hepatocyte growth factor is essential for amelioration of hyperglycemia in streptozotocin-induced diabetic mice receiving a marginal mass of intrahepatic islet grafts. Transplantation, 69, 214-221.
    • (2000) Transplantation , vol.69 , pp. 214-221
    • Nakano, M.1    Yasunami, Y.2    Maki, T.3    Kodama, S.4    Ikehara, Y.5    Nakamura, T.6    Tanaka, M.7    Ikeda, S.8
  • 42
    • 0842334620 scopus 로고    scopus 로고
    • Hepatocyte growth factor gene therapy for pancreatic islets in diabetes: Reducing the minimal islet transplant mass required in a glucocorticoid-free rat model of allogeneic portal vein islet transplantation
    • Lopez-Talavera, J. C., Garcia-Ocana, A., Sipula, I., Takane, K. K., Cozar-Castellano, I., & Stewart, A. F. (2004). Hepatocyte growth factor gene therapy for pancreatic islets in diabetes: Reducing the minimal islet transplant mass required in a glucocorticoid-free rat model of allogeneic portal vein islet transplantation. Endocrinology, 145, 467-474.
    • (2004) Endocrinology , vol.145 , pp. 467-474
    • Lopez-Talavera, J.C.1    Garcia-Ocana, A.2    Sipula, I.3    Takane, K.K.4    Cozar-Castellano, I.5    Stewart, A.F.6
  • 43
    • 0035213887 scopus 로고    scopus 로고
    • A kinase in the life of the beta cell
    • Accili, D. (2001). A kinase in the life of the beta cell. Journal of Clinical Investigation, 108, 1575-1576.
    • (2001) Journal of Clinical Investigation , vol.108 , pp. 1575-1576
    • Accili, D.1
  • 44
    • 0035499454 scopus 로고    scopus 로고
    • Ten years of protein kinase B signaling: A hard Akt to follow
    • Brazil, D. P., & Hemmings, B. A. (2001). Ten years of protein kinase B signaling: a hard Akt to follow. Trends in Biochemical Sciences, 26, 657-664.
    • (2001) Trends in Biochemical Sciences , vol.26 , pp. 657-664
    • Brazil, D.P.1    Hemmings, B.A.2
  • 45
    • 0036687655 scopus 로고    scopus 로고
    • Mechanisms of mitogenic and antiapoptotic signaling by glucose-dependent insulin-otropic polypeptide in beta (INS-1)-cells
    • Trumper, A., Trumper, K., & Horsch, D. (2002). Mechanisms of mitogenic and antiapoptotic signaling by glucose-dependent insulin-otropic polypeptide in beta (INS-1)-cells. Journal of Endocrinology, 174, 233-246.
    • (2002) Journal of Endocrinology , vol.174 , pp. 233-246
    • Trumper, A.1    Trumper, K.2    Horsch, D.3
  • 47
    • 2542479899 scopus 로고    scopus 로고
    • Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut and central nervous system
    • Brubaker, P. L., & Drucker, D. J. (2004). Minireview: Glucagon-like peptides regulate cell proliferation and apoptosis in the pancreas, gut and central nervous system. Endocrinology, 14, 2653-2659.
    • (2004) Endocrinology , vol.14 , pp. 2653-2659
    • Brubaker, P.L.1    Drucker, D.J.2
  • 48
    • 0035877778 scopus 로고    scopus 로고
    • Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1)
    • Dickson, L. M., Lingohr, M. K., McCuaig, J., Hugl, S. R., Snow, L., Kahn, B. B., Myers, M. G. Jr., & Rhodes, C. J. (2001). Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1). Journal of Biological Chemistry, 276, 21110-21120.
    • (2001) Journal of Biological Chemistry , vol.276 , pp. 21110-21120
    • Dickson, L.M.1    Lingohr, M.K.2    McCuaig, J.3    Hugl, S.R.4    Snow, L.5    Kahn, B.B.6    Myers Jr., M.G.7    Rhodes, C.J.8
  • 50
    • 4644333142 scopus 로고    scopus 로고
    • Cross-talk between phosphatidylinositiol 3-kinase/Akt and c-Jun NH2-terminal kinase mediates survival of isolated human islets
    • Aikin, R., Maysinger, D., & Rosenberg, L. (2004). Cross-talk between phosphatidylinositiol 3-kinase/Akt and c-Jun NH2-terminal kinase mediates survival of isolated human islets. Endocrinology, 145, 4522-4531.
    • (2004) Endocrinology , vol.145 , pp. 4522-4531
    • Aikin, R.1    Maysinger, D.2    Rosenberg, L.3
  • 52
    • 0035210374 scopus 로고    scopus 로고
    • Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia
    • Bernal-Mizrachi, E., Wen, W., Stahlhut, S., Welling, C. M., & Permutt M. A. (2001). Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia. Journal of Clinical Investigation, 108, 1631-1638.
    • (2001) Journal of Clinical Investigation , vol.108 , pp. 1631-1638
    • Bernal-Mizrachi, E.1    Wen, W.2    Stahlhut, S.3    Welling, C.M.4    Permutt, M.A.5
  • 53
    • 0037147215 scopus 로고    scopus 로고
    • Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1)
    • Wrede, C. E., Dickson, L. M., Lingohr, M. K., Briaud, I., & Rhodes, C. J. (2002). Protein kinase B/Akt prevents fatty acid-induced apoptosis in pancreatic beta-cells (INS-1). Journal of Biological Chemistry, 277, 49676-49684.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 49676-49684
    • Wrede, C.E.1    Dickson, L.M.2    Lingohr, M.K.3    Briaud, I.4    Rhodes, C.J.5
  • 54
    • 0141796313 scopus 로고    scopus 로고
    • Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts
    • Mangi, A. A., Noiseux, N., Kong, D., He, H., Rezvani, M., Ingwall, J. S., & Dzau, V. J. (2003). Mesenchymal stem cells modified with Akt prevent remodeling and restore performance of infarcted hearts. Nature Medicine, 9, 1195-1201.
    • (2003) Nature Medicine , vol.9 , pp. 1195-1201
    • Mangi, A.A.1    Noiseux, N.2    Kong, D.3    He, H.4    Rezvani, M.5    Ingwall, J.S.6    Dzau, V.J.7
  • 55
    • 0037184318 scopus 로고    scopus 로고
    • Simvastatin induces activation of the serine-threonine protein kinase Akt and increases survival of isolated human pancreatic islets
    • Contreras, J. L., Smyth, C. A., Bilbao, G., Young, C. J., Thompson, J. A., & Eckhoff, D. E. (2002). Simvastatin induces activation of the serine-threonine protein kinase Akt and increases survival of isolated human pancreatic islets. Transplantation, 74, 1063-1069.
    • (2002) Transplantation , vol.74 , pp. 1063-1069
    • Contreras, J.L.1    Smyth, C.A.2    Bilbao, G.3    Young, C.J.4    Thompson, J.A.5    Eckhoff, D.E.6
  • 56
    • 20044384383 scopus 로고    scopus 로고
    • Gene transfer of constitutively active Akt markedly improves human islet transplant outcomes in diabetic severe combined immunodeficient mice
    • Rao, P., Roccisana, J., Takane, K. K., Bottino, R., Zhao, A., Trucco, M., & Garcia-Ocana, A. (2005). Gene transfer of constitutively active Akt markedly improves human islet transplant outcomes in diabetic severe combined immunodeficient mice. Diabetes, 54, 1664-1675.
    • (2005) Diabetes , vol.54 , pp. 1664-1675
    • Rao, P.1    Roccisana, J.2    Takane, K.K.3    Bottino, R.4    Zhao, A.5    Trucco, M.6    Garcia-Ocana, A.7
  • 57
    • 24144447290 scopus 로고    scopus 로고
    • The x-linked inhibitor of apoptosis protein enhances survival of murine islet allografts
    • Plesner, A., Liston, P., Tan, R., Korneluk, R. G., & Verchere, C. B. (2005). The x-linked inhibitor of apoptosis protein enhances survival of murine islet allografts. Diabetes, 54, 2533-2540.
    • (2005) Diabetes, 54 , pp. 2533-2540
    • Plesner, A.1    Liston, P.2    Tan, R.3    Korneluk, R.G.4    Verchere, C.B.5


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