Cortical spreading depression releases ATP into the extracellular space and purinergic receptor activation contributes to the induction of ischemic tolerance

Brain Research

Volumn 1168, Issue 1, 2007, Pages 129-138

  Schock, Sarah C ^a   Munyao, Nzau ^b,c   Yakubchyk, Yury ^b   Sabourin, Luc A ^a,b   Hakim, Antoine M ^a,b   Ventureyra, Enrique C G ^c   Thompson, Charlie S ^a,b  

^a UNIVERSITY OF OTTAWA   (Canada)

^b OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^c CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

Author keywords

Adenosine; ATP; Cortical spreading depression; P2X receptor; P2Y receptor; Preconditioning

Indexed keywords

ADENOSINE; ADENOSINE TRIPHOSPHATE; CYCLIC AMP DEPENDENT PROTEIN KINASE; GLUCOSE; GLUTAMIC ACID; OXYGEN; PHOSPHOLIPASE C; PURINE P2Y RECEPTOR; PURINE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN ISCHEMIA TOLERANCE; CONTROLLED STUDY; EXTRACELLULAR SPACE; GENOME ANALYSIS; HYPOXIA; MALE; METABOLIC BALANCE; NERVE CELL CULTURE; NEUROPROTECTION; NONHUMAN; PHYSICAL SENSITIVITY AND TOLERANCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RAT; SIGNAL TRANSDUCTION; SPREADING CORTICAL DEPRESSION;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; CYANATES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, MAMMALIAN; ENZYME INHIBITORS; EXTRACELLULAR SPACE; FEMALE; GLUCOSE; ISCHEMIA; ISCHEMIC PRECONDITIONING; MALE; NEURONS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC; SPREADING CORTICAL DEPRESSION; TIME FACTORS;

RATTUS;

EID: 34548266197     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.06.070     Document Type: Article

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