메뉴 건너뛰기




Volumn 7, Issue SUPPL. 1, 2007, Pages

Biology of bone metastases: Causes and consequences

Author keywords

Bisphosphonates; Denosumab; Osteoclasts; RANK; Skeletal complications

Indexed keywords

ALKALINE PHOSPHATASE; ANASTROZOLE; BONE CEMENT; CALCIUM; CLODRONIC ACID; DENOSUMAB; ENDOTHELIN RECEPTOR ANTAGONIST; IBANDRONIC ACID; OSTEOCALCIN; OSTEOCLAST DIFFERENTIATION FACTOR; PAMIDRONIC ACID; SAMARIUM; STRONTIUM 90; TAMOXIFEN; VITAMIN D; ZOLEDRONIC ACID;

EID: 34548262727     PISSN: 15268209     EISSN: None     Source Type: Journal    
DOI: 10.3816/CBC.2007.s.001     Document Type: Article
Times cited : (37)

References (52)
  • 1
    • 0035010803 scopus 로고    scopus 로고
    • Metastatic bone disease: Clinical features, pathophysiology and treatment strategies
    • Coleman RE. Metastatic bone disease: clinical features, pathophysiology and treatment strategies. Cancer Treat Rev 2001; 27:165-176.
    • (2001) Cancer Treat Rev , vol.27 , pp. 165-176
    • Coleman, R.E.1
  • 2
    • 15344340489 scopus 로고    scopus 로고
    • Management of bone metastases in breast cancer
    • Lipton A. Management of bone metastases in breast cancer. Curr Treat Options Oncol 2005; 6:161-171.
    • (2005) Curr Treat Options Oncol , vol.6 , pp. 161-171
    • Lipton, A.1
  • 3
    • 13844314054 scopus 로고    scopus 로고
    • The cost of treatment of skeletal-related events in patients with bone metastases from lung cancer
    • Delea T, Langer C, McKiernan J, et al. The cost of treatment of skeletal-related events in patients with bone metastases from lung cancer. Oncology 2004; 67:390-396.
    • (2004) Oncology , vol.67 , pp. 390-396
    • Delea, T.1    Langer, C.2    McKiernan, J.3
  • 4
    • 0034846708 scopus 로고    scopus 로고
    • Pharmacoeconomic issues in bisphosphonate treatment of metastatic bone disease
    • Hillner BE. Pharmacoeconomic issues in bisphosphonate treatment of metastatic bone disease. Semin Oncol 2001; 28(4 suppl 11):64-68.
    • (2001) Semin Oncol , vol.28 , Issue.4 SUPPL. 11 , pp. 64-68
    • Hillner, B.E.1
  • 5
    • 33744813556 scopus 로고    scopus 로고
    • Genes associated with breast cancer metastatic to bone
    • Smid M, Wang Y, Jan GM, et al. Genes associated with breast cancer metastatic to bone. J Clin Oncol 2006; 24:2261-2267.
    • (2006) J Clin Oncol , vol.24 , pp. 2261-2267
    • Smid, M.1    Wang, Y.2    Jan, G.M.3
  • 7
    • 0036675220 scopus 로고    scopus 로고
    • Metastasis to bone: Causes, consequences and therapeutic opportunities
    • Mundy GR. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer 2002; 2:584-593.
    • (2002) Nat Rev Cancer , vol.2 , pp. 584-593
    • Mundy, G.R.1
  • 8
    • 4644261592 scopus 로고    scopus 로고
    • Mechanisms of bone matastases
    • Roodman DG. Mechanisms of bone matastases. N Engl J Med 2004; 350:1655-1664.
    • (2004) N Engl J Med , vol.350 , pp. 1655-1664
    • Roodman, D.G.1
  • 9
    • 24744434638 scopus 로고    scopus 로고
    • Molecular mechanisms of breast cancer metastases to bone
    • Guise TA, Kozlow WM, Heras-Herzig A, et al. Molecular mechanisms of breast cancer metastases to bone. Clin Breast Cancer 2005; 5(suppl 2):S46-S53.
    • (2005) Clin Breast Cancer , vol.5 , Issue.SUPPL. 2
    • Guise, T.A.1    Kozlow, W.M.2    Heras-Herzig, A.3
  • 10
    • 28244452125 scopus 로고    scopus 로고
    • Tumor-derived interleukin-8 stimulates osteolysis independent of the receptor activator of nuclear factor-kappaB ligand pathway
    • Bendre MS, Margulies AG, Walser B, et al. Tumor-derived interleukin-8 stimulates osteolysis independent of the receptor activator of nuclear factor-kappaB ligand pathway. Cancer Res 2005; 65:11001-11009.
    • (2005) Cancer Res , vol.65 , pp. 11001-11009
    • Bendre, M.S.1    Margulies, A.G.2    Walser, B.3
  • 11
    • 22744455581 scopus 로고    scopus 로고
    • Breast cancer metastasis to bone: Mechanisms of osteolysis and implications for therapy
    • Kozlow W, Guise TA. Breast cancer metastasis to bone: mechanisms of osteolysis and implications for therapy. J Mammary Gland Biol Neoplasia 2005; 10:169-180.
    • (2005) J Mammary Gland Biol Neoplasia , vol.10 , pp. 169-180
    • Kozlow, W.1    Guise, T.A.2
  • 12
    • 0142250340 scopus 로고    scopus 로고
    • Transforming growth factor-beta in osteolytic breast cancer bone metastases
    • Guise TA, Chirgwin JM. Transforming growth factor-beta in osteolytic breast cancer bone metastases. Clin Orthop Relat Res 2003; 415(suppl):S32-S38.
    • (2003) Clin Orthop Relat Res , vol.415 , Issue.SUPPL.
    • Guise, T.A.1    Chirgwin, J.M.2
  • 13
    • 0034839620 scopus 로고    scopus 로고
    • Preclinical models of bone metastases
    • Mundy G. Preclinical models of bone metastases. Semin Oncol 2001; 28(4 suppl 11):2-8.
    • (2001) Semin Oncol , vol.28 , Issue.4 SUPPL. 11 , pp. 2-8
    • Mundy, G.1
  • 15
    • 0035021176 scopus 로고    scopus 로고
    • Osteoprotegerin inhibits prostate cancer-induced osteoclastogenesis and prevents prostate tumor growth in the bone
    • Zhang J, Dai J, Qi Y, et al. Osteoprotegerin inhibits prostate cancer-induced osteoclastogenesis and prevents prostate tumor growth in the bone. J Clin Invest 2001; 107:1235-1244.
    • (2001) J Clin Invest , vol.107 , pp. 1235-1244
    • Zhang, J.1    Dai, J.2    Qi, Y.3
  • 16
    • 0142157085 scopus 로고    scopus 로고
    • Mechanisms of osteoblastic metastases: Role of endothelin-1
    • Mohammad KS, Guise TA. Mechanisms of osteoblastic metastases: role of endothelin-1. Clin Orthop Relat Res 2003; 415(suppl):S67-S74.
    • (2003) Clin Orthop Relat Res , vol.415 , Issue.SUPPL.
    • Mohammad, K.S.1    Guise, T.A.2
  • 17
    • 0034162528 scopus 로고    scopus 로고
    • Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases: Long term follow-up of two randomized, placebo-controlled trials
    • Lipton A, Theriault RL, Hortobagyi GN, et al. Pamidronate prevents skeletal complications and is effective palliative treatment in women with breast carcinoma and osteolytic bone metastases: long term follow-up of two randomized, placebo-controlled trials. Cancer 2000; 88:1082-1090.
    • (2000) Cancer , vol.88 , pp. 1082-1090
    • Lipton, A.1    Theriault, R.L.2    Hortobagyi, G.N.3
  • 18
    • 2942518111 scopus 로고    scopus 로고
    • Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer
    • Saad F, Gleason DM, Murray R, et al. Long-term efficacy of zoledronic acid for the prevention of skeletal complications in patients with metastatic hormone-refractory prostate cancer. J Natl Cancer Inst 2004; 96:879-882.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 879-882
    • Saad, F.1    Gleason, D.M.2    Murray, R.3
  • 19
    • 10744233021 scopus 로고    scopus 로고
    • Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: A randomized, duoble-blind, multicenter comparative trial
    • Rosen LS, Gordon D, Kaminski M, et al. Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, duoble-blind, multicenter comparative trial. Cancer 2003; 98:1735-1744.
    • (2003) Cancer , vol.98 , pp. 1735-1744
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3
  • 20
    • 0042914647 scopus 로고    scopus 로고
    • Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: A phase III, double-blind, randomized trial - the Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group
    • Rosen LS, Gordon D, Tchekmedyian S, et al. Zoledronic acid versus placebo in the treatment of skeletal metastases in patients with lung cancer and other solid tumors: a phase III, double-blind, randomized trial - the Zoledronic Acid Lung Cancer and Other Solid Tumors Study Group. J Clin Oncol 2003; 21:3150-3157.
    • (2003) J Clin Oncol , vol.21 , pp. 3150-3157
    • Rosen, L.S.1    Gordon, D.2    Tchekmedyian, S.3
  • 21
    • 18744424072 scopus 로고    scopus 로고
    • The new bishosphonate, Zometa (zoledronic acid), decreases skeletal complications in both osteolytic and osteoblastic lesions: A comparison to pamidronate
    • Lipton A, Small E, Saad F, et al. The new bishosphonate, Zometa (zoledronic acid), decreases skeletal complications in both osteolytic and osteoblastic lesions: a comparison to pamidronate. Cancer Invest 2002; 20(suppl 2):45-54.
    • (2002) Cancer Invest , vol.20 , Issue.SUPPL. 2 , pp. 45-54
    • Lipton, A.1    Small, E.2    Saad, F.3
  • 22
    • 0031056437 scopus 로고    scopus 로고
    • Malignant bone pain: Pathophysiology and treatment
    • Mercadante S. Malignant bone pain: pathophysiology and treatment. Pain 1997; 69:1-18.
    • (1997) Pain , vol.69 , pp. 1-18
    • Mercadante, S.1
  • 24
    • 0029267355 scopus 로고
    • The management of hypercalcemia of malignancy
    • Harvey HA. The management of hypercalcemia of malignancy. Support Care Cancer 1995; 3:123-129.
    • (1995) Support Care Cancer , vol.3 , pp. 123-129
    • Harvey, H.A.1
  • 25
    • 0036913512 scopus 로고    scopus 로고
    • The use of zoledronic acid, a novel, highly potent bisphosphonate, for the treatment of hypercalcemia of malignancy
    • Major P. The use of zoledronic acid, a novel, highly potent bisphosphonate, for the treatment of hypercalcemia of malignancy. Oncologist 2002; 7:481-491.
    • (2002) Oncologist , vol.7 , pp. 481-491
    • Major, P.1
  • 26
    • 0023137823 scopus 로고
    • The clinical course of bone metastases from breast cancer
    • Coleman RE, Rubens RD. The clinical course of bone metastases from breast cancer. Br J Cancer 1987; 55:61-66.
    • (1987) Br J Cancer , vol.55 , pp. 61-66
    • Coleman, R.E.1    Rubens, R.D.2
  • 27
    • 4644340347 scopus 로고    scopus 로고
    • Skeletal complications in patients with bone metastases from renal cell carcinoma and therapeutic benefits of zoledronic acid
    • Lipton A, Colombo-Berra A, Bukowski RM, et al. Skeletal complications in patients with bone metastases from renal cell carcinoma and therapeutic benefits of zoledronic acid. Clin Cancer Res 2004; 10:S6397-S6403.
    • (2004) Clin Cancer Res , vol.10
    • Lipton, A.1    Colombo-Berra, A.2    Bukowski, R.M.3
  • 28
    • 34548266109 scopus 로고    scopus 로고
    • Fractures negatively affect survival in patients with bone metastases from breast cancer
    • Abstract
    • Hei YJ. Fractures negatively affect survival in patients with bone metastases from breast cancer. Breast Cancer Res Treat 2005; 94:260 (Abstract #6036).
    • (2005) Breast Cancer Res Treat , vol.94 , Issue.6036 , pp. 260
    • Hei, Y.J.1
  • 29
    • 4344569455 scopus 로고    scopus 로고
    • Bone imaging in metastatic breast cancer
    • Hamaoka T, Madwell JE, Podoloff DA, et al. Bone imaging in metastatic breast cancer. J Clin Oncol 2004; 22:2942-2953.
    • (2004) J Clin Oncol , vol.22 , pp. 2942-2953
    • Hamaoka, T.1    Madwell, J.E.2    Podoloff, D.A.3
  • 30
    • 33646229295 scopus 로고    scopus 로고
    • Biochemical bone markers in breast cancer
    • Lipton A. Biochemical bone markers in breast cancer. Cancer Treat Rev 2006; 32:20-22.
    • (2006) Cancer Treat Rev , vol.32 , pp. 20-22
    • Lipton, A.1
  • 32
    • 24644479228 scopus 로고    scopus 로고
    • Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledronic acid
    • Coleman RE, Major P, Lipton A. Predictive value of bone resorption and formation markers in cancer patients with bone metastases receiving the bisphosphonate zoledronic acid. J Clin Oncol 2005; 23:4925-4935.
    • (2005) J Clin Oncol , vol.23 , pp. 4925-4935
    • Coleman, R.E.1    Major, P.2    Lipton, A.3
  • 33
    • 22444444683 scopus 로고    scopus 로고
    • Radiopharmaceuticals for the palliation of painful bone metastasis- a systemic review
    • Bauman G, Charette M, Reid R, et al. Radiopharmaceuticals for the palliation of painful bone metastasis- a systemic review. Radiother Oncol 2005; 75:258-270.
    • (2005) Radiother Oncol , vol.75 , pp. 258-270
    • Bauman, G.1    Charette, M.2    Reid, R.3
  • 34
    • 18544382657 scopus 로고    scopus 로고
    • Surgical treatment of bone metastasis: Indications and outcomes
    • Manabe J, Kawaguchi N, Matsumoto S. Surgical treatment of bone metastasis: indications and outcomes. Int J Clin Oncol 2005; 10:103-111.
    • (2005) Int J Clin Oncol , vol.10 , pp. 103-111
    • Manabe, J.1    Kawaguchi, N.2    Matsumoto, S.3
  • 35
    • 0032468984 scopus 로고    scopus 로고
    • Bisphosphonates: Mechanisms of action
    • Fleisch H. Bisphosphonates: mechanisms of action. Endocr Rev 1998; 19:80-100.
    • (1998) Endocr Rev , vol.19 , pp. 80-100
    • Fleisch, H.1
  • 36
    • 0035146537 scopus 로고    scopus 로고
    • Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates
    • Dunford JE, Thompson K, Coxon FP, et al. Structure-activity relationships for inhibition of farnesyl diphosphate synthase in vitro and inhibition of bone resorption in vivo by nitrogen-containing bisphosphonates. J Pharm Exp Ther 2001; 296:235-242.
    • (2001) J Pharm Exp Ther , vol.296 , pp. 235-242
    • Dunford, J.E.1    Thompson, K.2    Coxon, F.P.3
  • 37
    • 10744233021 scopus 로고    scopus 로고
    • Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: A randomized, double-blind, multicenter, comparative trial
    • Rosen LS, Gordon D, Kaminski M, et al. Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double-blind, multicenter, comparative trial. Cancer 2003; 98:1735-1744.
    • (2003) Cancer , vol.98 , pp. 1735-1744
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3
  • 38
    • 17144447171 scopus 로고    scopus 로고
    • Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases
    • Body JJ, Diel IJ, Lichinitser MR, et al. Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases. Ann Oncol 2003; 14:1399-1405.
    • (2003) Ann Oncol , vol.14 , pp. 1399-1405
    • Body, J.J.1    Diel, I.J.2    Lichinitser, M.R.3
  • 39
    • 0642342669 scopus 로고    scopus 로고
    • American Society of Clinical Oncology 2003 update on the role of bisphosphonates and bone health issues in women with breast cancer
    • Hillner BE, Ingle JN, Chlebowski RT, et al. American Society of Clinical Oncology 2003 update on the role of bisphosphonates and bone health issues in women with breast cancer. J Clin Oncol 2003; 21:4042-4057.
    • (2003) J Clin Oncol , vol.21 , pp. 4042-4057
    • Hillner, B.E.1    Ingle, J.N.2    Chlebowski, R.T.3
  • 40
    • 33644760436 scopus 로고    scopus 로고
    • A study of the biologic receptor activator of nuclear factor-kappaB ligand inhibitor, denosumab, in patients with multiple myeloma or bone metastases from breast cancer
    • Body JJ, Facon T, Coleman RE, et al. A study of the biologic receptor activator of nuclear factor-kappaB ligand inhibitor, denosumab, in patients with multiple myeloma or bone metastases from breast cancer. Clin Cancer Res 2006; 12:1221-1228.
    • (2006) Clin Cancer Res , vol.12 , pp. 1221-1228
    • Body, J.J.1    Facon, T.2    Coleman, R.E.3
  • 41
    • 34548265138 scopus 로고    scopus 로고
    • Phase II trial of denosumab in breast cancer with bone metastases
    • 18 suppl):6S Abstract #512
    • Lipton A. Phase II trial of denosumab in breast cancer with bone metastases. J Clin Oncol 2006; 24(18 suppl):6S (Abstract #512).
    • (2006) J Clin Oncol , pp. 24
    • Lipton, A.1
  • 42
    • 0035148170 scopus 로고    scopus 로고
    • Adjuvant clodronate treatment does not reduce the frequency of skeletal metastases in node-positive breast cancer patients: 5 year results of a randomized controlled trial
    • Saarto T, Blomqvist C, Virkkunen P, et al. Adjuvant clodronate treatment does not reduce the frequency of skeletal metastases in node-positive breast cancer patients: 5 year results of a randomized controlled trial. J Clin Oncol 2001; 19:10-17.
    • (2001) J Clin Oncol , vol.19 , pp. 10-17
    • Saarto, T.1    Blomqvist, C.2    Virkkunen, P.3
  • 43
    • 0032491037 scopus 로고    scopus 로고
    • Reduction in new metastases in breast cancer with adjuvant clodronate treatment
    • Diel IJ, Solomayer EF, Costa SD, et al. Reduction in new metastases in breast cancer with adjuvant clodronate treatment. N Engl J Med 1998; 339:357-363.
    • (1998) N Engl J Med , vol.339 , pp. 357-363
    • Diel, I.J.1    Solomayer, E.F.2    Costa, S.D.3
  • 44
    • 33744828376 scopus 로고    scopus 로고
    • Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer
    • Powles T, Paterson A, McCloskey E. Reduction in bone relapse and improved survival with oral clodronate for adjuvant treatment of operable breast cancer. Breast Cancer Res 2006; 8:13.
    • (2006) Breast Cancer Res , vol.8 , pp. 13
    • Powles, T.1    Paterson, A.2    McCloskey, E.3
  • 45
    • 33746455931 scopus 로고    scopus 로고
    • Effect of an aromatase inhibitor on BMD and bone turnover markers: 2-year results of the Anastrozole, Tamoxifen, Alone or in Combination (ATAC) trial. ATAC Trialists' Group
    • Eastell R, Hannon RA, Cuzick J, et al. Effect of an aromatase inhibitor on BMD and bone turnover markers: 2-year results of the Anastrozole, Tamoxifen, Alone or in Combination (ATAC) trial. ATAC Trialists' Group. J Bone Miner Res 2006; 21:1215-1223.
    • (2006) J Bone Miner Res , vol.21 , pp. 1215-1223
    • Eastell, R.1    Hannon, R.A.2    Cuzick, J.3
  • 46
    • 10744223655 scopus 로고    scopus 로고
    • A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer
    • Coombes RC, Hall E, Gibson LJ, et al. A randomized trial of exemestane after two to three years of tamoxifen therapy in postmenopausal women with primary breast cancer. N Engl J Med 2004; 350:1081-1092.
    • (2004) N Engl J Med , vol.350 , pp. 1081-1092
    • Coombes, R.C.1    Hall, E.2    Gibson, L.J.3
  • 47
    • 29544433211 scopus 로고    scopus 로고
    • A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer
    • Thurlimann B, Keshaviah A, Coates AS, et al. A comparison of letrozole and tamoxifen in postmenopausal women with early breast cancer. N Engl J Med 2005; 353:2747-2757.
    • (2005) N Engl J Med , vol.353 , pp. 2747-2757
    • Thurlimann, B.1    Keshaviah, A.2    Coates, A.S.3
  • 48
    • 4344572856 scopus 로고    scopus 로고
    • The role of bisphosphonates in men with prostate cancer receiving androgen deprivation therapy
    • Smith MR. The role of bisphosphonates in men with prostate cancer receiving androgen deprivation therapy. Oncology 2004; 18:21-25.
    • (2004) Oncology , vol.18 , pp. 21-25
    • Smith, M.R.1
  • 49
    • 33746555619 scopus 로고    scopus 로고
    • Zoledronic acid initiated during the first year of androgen deprivation therapy increases bone mineral density in patients with prostate cancer
    • Ryan CW, Huo D, Demers L, et al. Zoledronic acid initiated during the first year of androgen deprivation therapy increases bone mineral density in patients with prostate cancer. J Urol 2006; 176:972-978.
    • (2006) J Urol , vol.176 , pp. 972-978
    • Ryan, C.W.1    Huo, D.2    Demers, L.3
  • 50
    • 33646468937 scopus 로고    scopus 로고
    • Management of bone loss induced by aromatase inhibitors
    • Gnant M. Management of bone loss induced by aromatase inhibitors. Cancer Inv 2006; 24:328-330.
    • (2006) Cancer Inv , vol.24 , pp. 328-330
    • Gnant, M.1
  • 51
    • 33646793674 scopus 로고    scopus 로고
    • Management of cancer treatment induced bone loss in postmenopausal women undergoing adjuvant breast cancer therapy: A Z-FAST update
    • Brufsky A. Management of cancer treatment induced bone loss in postmenopausal women undergoing adjuvant breast cancer therapy: a Z-FAST update. Semin Oncol 2006; 33:S13-S17.
    • (2006) Semin Oncol , vol.33
    • Brufsky, A.1
  • 52
    • 18144427485 scopus 로고    scopus 로고
    • Optimizing bisphosphonate therapy in patients with breast cancer on endocrine therapy
    • Harvey HA. Optimizing bisphosphonate therapy in patients with breast cancer on endocrine therapy. Semin Oncol 2004; 31(6 suppl 12):23-30.
    • (2004) Semin Oncol , vol.31 , Issue.6 SUPPL. 12 , pp. 23-30
    • Harvey, H.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.