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Volumn 87, Issue 21, 2007, Pages 1506-1509

shRNA-mediated insulin-like growth factor I receptor gene silencing inhibits cell proliferation, induces cell apoptosis, and suppresses tumor growth in non-small cell lung cancer: In vitro and in vivo experiments

Author keywords

Lung neoplasms; Receptor, IGF type 1; RNA interfercnce

Indexed keywords

CASPASE 3; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BCL 2; PROTEIN KINASE B; SHORT HAIRPIN RNA; SOMATOMEDIN C RECEPTOR;

EID: 34548242651     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (2)

References (10)
  • 1
    • 0031034574 scopus 로고    scopus 로고
    • Antiapoptotic signaling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt
    • Kulik G, Klippel A, Weber MJ. Antiapoptotic signaling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt. Mol Cell Biol, 1997, 17:1595-1606.
    • (1997) Mol Cell Biol , vol.17 , pp. 1595-1606
    • Kulik, G.1    Klippel, A.2    Weber, M.J.3
  • 2
    • 0042515293 scopus 로고    scopus 로고
    • An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation
    • Maloney EK, McLaughlin JL, Dagdigian NE, et al. An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation. Cancer Res, 2003, 63:5073-5083.
    • (2003) Cancer Res , vol.63 , pp. 5073-5083
    • Maloney, E.K.1    McLaughlin, J.L.2    Dagdigian, N.E.3
  • 3
    • 0037277323 scopus 로고    scopus 로고
    • Recombinant adenoviruses expressing dominant negative insulin-like growth factor-I receptor demonstrate antitumor effectors on lung cancer
    • Lee CT, Park KH, Adachi Y, et al. Recombinant adenoviruses expressing dominant negative insulin-like growth factor-I receptor demonstrate antitumor effectors on lung cancer. Cancer Gene Ther, 2003, 10:57-63.
    • (2003) Cancer Gene Ther , vol.10 , pp. 57-63
    • Lee, C.T.1    Park, K.H.2    Adachi, Y.3
  • 4
    • 0029895283 scopus 로고    scopus 로고
    • Antitumor effects of an adenovirus expressing antisense insulin-like growth factor I receptor on tumor lung cancer cell lines
    • Lee CT, Wu S, Gabrilovich D, et al. Antitumor effects of an adenovirus expressing antisense insulin-like growth factor I receptor on tumor lung cancer cell lines. Cancer Res, 1996, 56:3038-3041.
    • (1996) Cancer Res , vol.56 , pp. 3038-3041
    • Lee, C.T.1    Wu, S.2    Gabrilovich, D.3
  • 5
    • 3142615372 scopus 로고    scopus 로고
    • The RNAi revolution
    • Novina CD, Sharp PA. The RNAi revolution. Nature, 2004, 430:161-164.
    • (2004) Nature , vol.430 , pp. 161-164
    • Novina, C.D.1    Sharp, P.A.2
  • 6
    • 0038521255 scopus 로고    scopus 로고
    • Bohula EA, Salisbury AJ, Sohail M, et al. The efficacy of small interfering RNNs targeted to the type 1 insulin-like growth factor receptor (IGF1R) is influenced by secondary structure in the IGF1R transcript. J Biol Chem, 2003, 278-15991-15997.
    • Bohula EA, Salisbury AJ, Sohail M, et al. The efficacy of small interfering RNNs targeted to the type 1 insulin-like growth factor receptor (IGF1R) is influenced by secondary structure in the IGF1R transcript. J Biol Chem, 2003, 278-15991-15997.
  • 7
    • 0028957113 scopus 로고
    • Molecular and cellular aspects of the insulin-like growth factor I receptor
    • LeRoith D, Werner H, Beitner-Johnson D, et al. Molecular and cellular aspects of the insulin-like growth factor I receptor. Endocr Rev, 1995, 16:143-163.
    • (1995) Endocr Rev , vol.16 , pp. 143-163
    • LeRoith, D.1    Werner, H.2    Beitner-Johnson, D.3
  • 8
    • 0036245628 scopus 로고    scopus 로고
    • U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells
    • Miyagishi M, Taira K. U6 promoter-driven siRNAs with four uridine 3′ overhangs efficiently suppress targeted gene expression in mammalian cells. Nat Biotechnol, 2002, 20:497-500.
    • (2002) Nat Biotechnol , vol.20 , pp. 497-500
    • Miyagishi, M.1    Taira, K.2
  • 9
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in culture in culture mammalian cells
    • Elbashir S, Harborth J, Lendeckel W, et al. Duplexes of 21-nucleotide RNAs mediate RNA interference in culture in culture mammalian cells. Nature, 2001, 411:494-498.
    • (2001) Nature , vol.411 , pp. 494-498
    • Elbashir, S.1    Harborth, J.2    Lendeckel, W.3
  • 10
    • 0037089135 scopus 로고    scopus 로고
    • Positional efects, of short interfering RNAs targeting the human coagulation trigger tissue factor
    • Holen T, Amarzguioui M, Wiiger MT, et al. Positional efects, of short interfering RNAs targeting the human coagulation trigger tissue factor. Nucleic Acids Res, 2002, 30:1757-1766.
    • (2002) Nucleic Acids Res , vol.30 , pp. 1757-1766
    • Holen, T.1    Amarzguioui, M.2    Wiiger, M.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.