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Volumn 41, Issue 5, 2006, Pages 442-454

AmpliChip for cytochrome P-450 genotyping: The epoch of personalized prescriptions

Author keywords

Amplichip; Genotyping; Pharmacogenomics; Polymorphisms

Indexed keywords


EID: 34548228302     PISSN: 00185787     EISSN: None     Source Type: Journal    
DOI: 10.1310/hpj4105-442     Document Type: Review
Times cited : (3)

References (63)
  • 1
    • 0032522873 scopus 로고    scopus 로고
    • Incidence of adverse drug reactions in hospitalized patients: A meta- Analysis of prospective studies
    • DOI 10.1001/jama.279.15.1200
    • Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: a meta-analysis of prospective studies. JAMA. 1998;279: 1200-1205. (Pubitemid 28193431)
    • (1998) Journal of the American Medical Association , vol.279 , Issue.15 , pp. 1200-1205
    • Lazarou, J.1    Pomeranz, B.H.2    Corey, P.N.3
  • 2
    • 0029130580 scopus 로고
    • Drug-related morbidity and mortality
    • Johnson JA, Bootman JL. Drug-related morbidity and mortality. Arch Intern Med. 1995;155:1949-1956.
    • (1995) Arch Intern Med , vol.155 , pp. 1949-1956
    • Johnson, J.A.1    Bootman, J.L.2
  • 5
    • 0242332641 scopus 로고    scopus 로고
    • Genetic polymorphism of cytochrome P450 enzymes in Asian populations: Focus on CYP2D6
    • Kitada M. Genetic polymorphism of cytochrome P450 enzymes in Asian populations: focus on CYP2D6. Int J Clin Pharmacol Res. 2003;23:31-35. (Pubitemid 37339363)
    • (2003) International Journal of Clinical Pharmacology Research , vol.23 , Issue.1 , pp. 31-35
    • Kitada, M.1
  • 6
    • 3242723840 scopus 로고    scopus 로고
    • The MDR1 (ABCB1) gene polymorphism and its clinical implications
    • DOI 10.2165/00003088-200443090-00001
    • Ieiri I, Takane H, Otsubo K. The MDR1 (ABCB1) gene polymorphism and its clinical implications. Clin Pharmacokinet. 2004;43:553-576. (Pubitemid 38951800)
    • (2004) Clinical Pharmacokinetics , vol.43 , Issue.9 , pp. 553-576
    • Ieiri, I.1    Takane, H.2    Otsubo, K.3
  • 9
    • 34250943612 scopus 로고
    • Enzymatische inaktivierung von isonicotinsaurehydrazid im menschlichen und tierischen organismus
    • Bonicke R, Reif W. Enzymatische inaktivierung von isonicotinsaurehydrazid im menschlichen und tierischen organismus. Arch Exper Pathol Pharmakol. 1953;220:321.
    • (1953) Arch Exper Pathol Pharmakol , vol.220 , pp. 321
    • Bonicke, R.1    Reif, W.2
  • 10
    • 0006948626 scopus 로고
    • Metabolism of isoniazid in man as related to the occurrence of peripheral neuritis
    • Hughes HB, Biehl JP, Jones AP, Schmidt LH. Metabolism of isoniazid in man as related to the occurrence of peripheral neuritis. Am Rev Tuberc. 1954;70:266-273.
    • (1954) Am Rev Tuberc , vol.70 , pp. 266-273
    • Hughes, H.B.1    Biehl, J.P.2    Jones, A.P.3    Schmidt, L.H.4
  • 11
    • 0036202380 scopus 로고    scopus 로고
    • Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis
    • Huang YS, Chern HD, Su WJ, et al. Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis. Hepatology. 2002;35:883-889.
    • (2002) Hepatology , vol.35 , pp. 883-889
    • Huang, Y.S.1    Chern, H.D.2    Su, W.J.3
  • 12
    • 0015916139 scopus 로고
    • Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype
    • Das KM, Eastwood MA, McManus JP, Sircus W. Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype. N Engl J Med. 1973;289:491-495.
    • (1973) N Engl J Med , vol.289 , pp. 491-495
    • Das, K.M.1    Eastwood, M.A.2    McManus, J.P.3    Sircus, W.4
  • 13
    • 14544294519 scopus 로고    scopus 로고
    • Structure and regulation of the drug-metabolizing enzymes arylamine N-acetyltransferases
    • Dupret JM, Rodrigues-Lima F. Structure and regulation of the drugmetabolizing enzymes arylamine Nacetyltransferases. Curr Med Chem. 2005;12:311-318. (Pubitemid 40305622)
    • (2005) Current Medicinal Chemistry , vol.12 , Issue.3 , pp. 311-318
    • Dupret, J.-M.1    Rodrigues-Lima, F.2
  • 17
    • 0033569516 scopus 로고    scopus 로고
    • Pharmacogenomics: Translating functional genomics into rational therapeutics
    • Evans WE, Relling MV. Pharmacogenomics: translating functional genomics into rational therapeutics. Science. 1999; 286: 487-491.
    • (1999) Science , vol.286 , pp. 487-491
    • Evans, W.E.1    Relling, M.V.2
  • 18
    • 10644241977 scopus 로고    scopus 로고
    • Pharmacogenetics of the cytochromes P450
    • Daly AK. Pharmacogenetics of the cytochromes P450. Curr Top Med Chem 2004;4(16):1733-1744.
    • (2004) Curr Top Med Chem , vol.4 , Issue.16 , pp. 1733-1744
    • Daly, A.K.1
  • 19
    • 13544249943 scopus 로고    scopus 로고
    • Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): Clinical consequences, evolutionary aspects and functional diversity
    • DOI 10.1038/sj.tpj.6500285
    • Ingelman-Sundberg M. Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity. Pharmacogenomics J. 2005;5:6-13. (Pubitemid 40220611)
    • (2005) Pharmacogenomics Journal , vol.5 , Issue.1 , pp. 6-13
    • Ingelman-Sundberg, M.1
  • 20
    • 0036124107 scopus 로고    scopus 로고
    • CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
    • Bradford LD. CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics. 2002;3:229-243.
    • (2002) Pharmacogenomics , vol.3 , pp. 229-243
    • Bradford, L.D.1
  • 21
    • 0034059585 scopus 로고    scopus 로고
    • Fluoxetine-related death in a child with cytochrome P-450 2D6 genetic deficiency
    • Sallee FR, DeVane CL, Ferrell RE. Fluoxetine-related death in a child with cytochrome P-450 2D6 genetic deficiency. J Child Adolesc Psychopharmacol. 2000;10:27-34.
    • (2000) J Child Adolesc Psychopharmacol , vol.10 , pp. 27-34
    • Sallee, F.R.1    DeVane, C.L.2    Ferrell, R.E.3
  • 22
    • 0020409410 scopus 로고
    • Oxidation phenotype. a major determinant of metoprolol metabolism and response
    • Lennard MS, Silas JH, Freestone S, Ramsay LE, Tucker GT, Woods HF. Oxidation phenotype-a major determinant of metoprolol metabolism and response. N Engl J Med. 1982;307:1558-1560. (Pubitemid 13245431)
    • (1982) New England Journal of Medicine , vol.307 , Issue.25 , pp. 1558-1560
    • Lennard, M.S.1    Silas, J.H.2    Freestone, S.3
  • 24
    • 0034792584 scopus 로고    scopus 로고
    • Clinical relevance of genetic polymorphisms in the human CYP2C subfamily
    • Goldstein JA. Clinical relevance of genetic polymorphisms in the human CYP2C subfamily. Br J Clin Pharmacol. 2001;52:349-355
    • (2001) Br J Clin Pharmacol , vol.52 , pp. 349-355
    • Goldstein, J.A.1
  • 25
    • 0036394942 scopus 로고    scopus 로고
    • Clinical significance of the cytochrome P450 2C19 genetic polymorphism
    • Desta Z, Zhao X, Shin JG, Flockhart DA. Clinical significance of the cytochrome P450 2C19 genetic polymorphism. Clin Pharmacokinet. 2002;41:913-958. (Pubitemid 35168437)
    • (2002) Clinical Pharmacokinetics , vol.41 , Issue.12 , pp. 913-958
    • Desta, Z.1    Zhao, X.2    Shin, J.-G.3    Flockhart, D.A.4
  • 26
    • 0031038038 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 variants in a Caucasian population: Allele frequencies and phenotypic consequences
    • Sachse C, Brockmoller J, Bauer S, Roots I. Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences. Am J Hum Genet. 1997;60:284-295. (Pubitemid 27058401)
    • (1997) American Journal of Human Genetics , vol.60 , Issue.2 , pp. 284-295
    • Sachse, C.1    Brockmoller, J.2    Bauer, S.3    Roots, I.4
  • 27
    • 0029028932 scopus 로고
    • Geographical interracial differences in polymorphic drug oxidation-current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19
    • Bertilsson L. Geographical interracial differences in polymorphic drug oxidation-current state of knowledge of cytochromes P450 (CYP) 2D6 and 2C19. Clin Pharmacokinet. 1995; 29:192-209.
    • (1995) Clin Pharmacokinet , vol.29 , pp. 192-209
    • Bertilsson, L.1
  • 29
    • 0242721764 scopus 로고    scopus 로고
    • Polymorphisms and the pocketbook: The cost-effectiveness of cytochrome P450 2C19 genotyping in the eradication of Helicobacter pylori infection associated with duodenal ulcer
    • Lehmann DF, Medicis JJ, Franklin PD. Polymorphisms and the pocketbook: the cost-effectiveness of cytochrome P450 2C19 genotyping in the eradication of Helicobacter pylori infection associated with duodenal ulcer. J Clin Pharmacol. 2003;43:1316-1323.
    • (2003) J Clin Pharmacol , vol.43 , pp. 1316-1323
    • Lehmann, D.F.1    Medicis, J.J.2    Franklin, P.D.3
  • 33
    • 27744480783 scopus 로고    scopus 로고
    • Assessment Of AmpliChip CYP450 based CYP2D6-genotyping and phenotype prediction compared to PCRRFLP-genotyping and phenotyping by metoprolol pharmacokinetics
    • A43
    • Heller T, Kirchheiner J, Armstrong VW, Luthe H, Brockmoller J, Oellerich M. Assessment Of AmpliChip CYP450 based CYP2D6-genotyping and phenotype prediction compared to PCRRFLP-genotyping and phenotyping by metoprolol pharmacokinetics. Ther Drug Monit. 2005;27:221, A43.
    • (2005) Ther Drug Monit , vol.27 , pp. 221
    • Heller, T.1    Kirchheiner, J.2    Armstrong, V.W.3    Luthe, H.4    Brockmoller, J.5    Oellerich, M.6
  • 34
    • 33645081095 scopus 로고    scopus 로고
    • Determination of CYP2D6 gene alleles by the CYP450 probe array using the Affymetrix GeneChip system: Comparison with sequencing results
    • Ishida S, Soyama A, Saito Y, et al. Determination of CYP2D6 gene alleles by the CYP450 probe array using the Affymetrix GeneChip system: comparison with sequencing results. Drug Metab Pharmacokinet. 2002;17:157-160.
    • (2002) Drug Metab Pharmacokinet , vol.17 , pp. 157-160
    • Ishida, S.1    Soyama, A.2    Saito, Y.3
  • 35
    • 14644400494 scopus 로고    scopus 로고
    • The impact of pharmacogenomics on postoperative nausea and vomiting: Do CYP2D6 allele copy number and polymorphisms affect the success or failure of ondansetron prophylaxis?
    • Candiotti KA, Birnbach DJ, Lubarsky DA, et al. The impact of pharmacogenomics on postoperative nausea and vomiting: do CYP2D6 allele copy number and polymorphisms affect the success or failure of ondansetron prophylaxis? Anesthesiology. 2005;102: 543-549.
    • (2005) Anesthesiology , vol.102 , pp. 543-549
    • Candiotti, K.A.1    Birnbach, D.J.2    Lubarsky, D.A.3
  • 36
    • 13844320650 scopus 로고    scopus 로고
    • The CYP2D6 poor metabolizer phenotype may be associated with risperidone adverse drug reactions and discontinuation
    • de Leon J, Susce MT, Pan RM, Fairchild M, Koch WH, Wedlund PJ. The CYP2D6 poor metabolizer phenotype may be associated with risperidone adverse drug reactions and discontinuation. J Clin Psychiatry. 2005;66:15-27.
    • (2005) J Clin Psychiatry , vol.66 , pp. 15-27
    • De Leon, J.1    Susce, M.T.2    Pan, R.M.3    Fairchild, M.4    Koch, W.H.5    Wedlund, P.J.6
  • 37
    • 85036842425 scopus 로고    scopus 로고
    • Seryx. LLC. Available at: Accessed June 14, 2005
    • Seryx. LLC. Signature genetics: the know how to be well. Available at: http://www.signaturegenetics.com/sgtiles/en/download/physician-nb-5684.pdf. Accessed June 14, 2005.
    • Signature Genetics: The Know How to Be Well
  • 38
    • 85036841067 scopus 로고    scopus 로고
    • Genelex Corporation. Available at: Accessed June 15, 2005
    • Genelex Corporation. Health and DNA. Available at: http://www. healthanddna.com/. Accessed June 15, 2005.
    • Health and DNA
  • 39
    • 0242422178 scopus 로고    scopus 로고
    • Quackwatch Web site. Available at: Accessed June 17, 2005
    • Barrett S, Hall H. Dubious genetic testing. Quackwatch Web site. Available at: http://www.quackwatch.org/01QuackeryRelatedTopics/Tests/genomics. html. Accessed June 17, 2005.
    • Dubious Genetic Testing
    • Barrett, S.1    Hall, H.2
  • 40
    • 85036839772 scopus 로고    scopus 로고
    • Genaissance Pharmaceuticals, Inc. Available at: Accessed June 15, 2005
    • Genaissance Pharmaceuticals, Inc. Pharmacogenomic support. Available at: http://www.dna.com/products-services/pgx-support-dd.html. Accessed June 15, 2005.
    • Pharmacogenomic Support
  • 41
    • 85036810318 scopus 로고    scopus 로고
    • Available at: Accessed June 15, 2005
    • DxS Ltd. Genetwork. Available at: http://www.dxsgenotyping.com/genetwork. htm. Accessed June 15, 2005.
    • Genetwork
  • 42
    • 85036816703 scopus 로고    scopus 로고
    • Available at: Accessed June 15, 2005
    • Third Wave Technologies, Inc. Proprietary invader technology. Available at: http://www.twt.com/invader-tech/inv-tech.htm. Accessed June 15, 2005.
    • Proprietary Invader Technology
  • 43
    • 85036838973 scopus 로고    scopus 로고
    • GE HealthCare. Available at: Accessed June 9, 2005
    • GE HealthCare. CodeLink System: bioarrays for gene expression & SNP analysis. Available at: http://www1.amershambiosciences.com/APTRIX/upp 01077.nsf/Content/codelink-bioarray-system. Accessed June 9, 2005.
    • CodeLink System: Bioarrays for Gene Expression & SNP Analysis
  • 44
    • 85036810496 scopus 로고    scopus 로고
    • Available at: Accessed June 15, 2005
    • Gentris Corporation. Diagnostic products. Available at: http://www.gentris.com/diagnostic/. Accessed June 15, 2005.
    • Diagnostic Products
  • 46
    • 19144373497 scopus 로고    scopus 로고
    • CYP2C9 haplotype structure in European American warfarin patients and association with clinical outcomes
    • Veenstra DL, Blough DK, Higashi MK, et al. CYP2C9 haplotype structure in European American warfarin patients and association with clinical outcomes. Clin Pharmacol Ther. 2005;77:353-364.
    • (2005) Clin Pharmacol Ther , vol.77 , pp. 353-364
    • Veenstra, D.L.1    Blough, D.K.2    Higashi, M.K.3
  • 47
    • 0028210729 scopus 로고
    • Impaired (S)-warfarin metabolism catalyzed by the R144C allelic variant of CYP2C9
    • Impaired (S)-warfarin metabolism catalyzed by the R144C allelic variant of CYP2C9. Pharmacogenetics.1994;4:39-42.
    • (1994) Pharmacogenetics , vol.4 , pp. 39-42
  • 49
    • 11844304376 scopus 로고    scopus 로고
    • Clinical consequences of cytochrome P450 2C9 polymorphisms
    • DOI 10.1016/j.clpt.2004.08.009, PII S0009923604002772
    • Kirchheiner J, Brockmoller J. Clinical consequences of cytochrome P4502C9 polymorphisms. Clin Pharmacol Ther. 2005;77:1-16. (Pubitemid 40089477)
    • (2005) Clinical Pharmacology and Therapeutics , vol.77 , Issue.1 , pp. 1-16
    • Kirchheiner, J.1    Brockmoller, J.2
  • 51
    • 11844304376 scopus 로고    scopus 로고
    • Clinical consequences of cytochrome P450 2C9 polymorphisms
    • DOI 10.1016/j.clpt.2004.08.009, PII S0009923604002772
    • Kirchheiner J, Brockmoller J. Clinical consequences of cytochrome P4502C9 polymorphisms. Clin Pharmacol Ther. 2005;77:1-16. (Pubitemid 40089477)
    • (2005) Clinical Pharmacology and Therapeutics , vol.77 , Issue.1 , pp. 1-16
    • Kirchheiner, J.1    Brockmoller, J.2
  • 52
    • 0035217171 scopus 로고    scopus 로고
    • Identification of a null allele of CYP2C9 in an African-American exhibiting toxicity to phenytoin
    • DOI 10.1097/00008571-200112000-00008
    • Kidd RS, Curry TB, Gallagher S, Edeki T, Blaisdell J, Goldstein JA. Identification of a null allele of CYP2C9 in an African-American exhibiting toxicity to phenytoin. Pharmacogenetics. 2001;11:803-808. (Pubitemid 33151515)
    • (2001) Pharmacogenetics , vol.11 , Issue.9 , pp. 803-808
    • Kidd, R.S.1    Curry, T.B.2    Gallagher, S.3    Edeki, T.4    Blaisdell, J.5    Goldstein, J.A.6
  • 54
    • 85036848294 scopus 로고    scopus 로고
    • The efficacy of omeprazole/esomeprazole-based firstline and rescue therapies for treatment of Helicobacter pylori infection is not affected by polymorphisms of cytochrome P450-2C19
    • Kirsch C, Schneider-Brachert W, Grossmann D, et al. The efficacy of omeprazole/esomeprazole-based firstline and rescue therapies for treatment of Helicobacter pylori infection is not affected by polymorphisms of cytochrome P450-2C19. Gastroenterology. 2004;126(suppl. 2): A189.
    • (2004) Gastroenterology , vol.126 , Issue.SUPPL. 2
    • Kirsch, C.1    Schneider-Brachert, W.2    Grossmann, D.3
  • 55
    • 3342997410 scopus 로고    scopus 로고
    • CYP2C19 polymorphism is a major predictor of treatment failure in white patients by use of lansoprazole-based quadruple therapy for eradication of Helicobacter pylori
    • DOI 10.1016/j.clpt.2004.05.002, PII S0009923604001420
    • Schwab M, Schaeffeler E, Klotz U, Treiber G. CYP2C19 polymorphism is a major predictor of treatment failure in white patients by use of lansoprazolebased quadruple therapy for eradication of Helicobacter pylori. Clin Pharmacol Ther. 2004;76:201-209. (Pubitemid 39221794)
    • (2004) Clinical Pharmacology and Therapeutics , vol.76 , Issue.3 , pp. 201-209
    • Schwab, M.1    Schaeffeler, E.2    Klotz, U.3    Treiber, G.4
  • 56
    • 0037380492 scopus 로고    scopus 로고
    • Pharmacogenetics of the proton pump inhibitors: A systematic review
    • DOI 10.1592/phco.23.4.460.32128
    • Chong E, Ensom MH. Pharmacogenetics of the proton pump inhibitors: a systematic review. Pharmacotherapy. 2003;23:460-471. (Pubitemid 36384325)
    • (2003) Pharmacotherapy , vol.23 , Issue.4 , pp. 460-471
    • Chong, E.1    Ensom, M.H.H.2
  • 57
    • 0030472254 scopus 로고    scopus 로고
    • Codeine and morphine in extensive and poor metabolizers of sparteine: Pharmacokinetics, analgesic effect and side effects
    • DOI 10.1007/s002280050200
    • Poulsen L, Brosen K, ArendtNielsen L, Gram LF, Elbaek K, Sindrup SH. Codeine and morphine in extensive and poor metabolizers of sparteine: pharmacokinetics, analgesic effect and side effects. Eur J Clin Pharmacol. 1996;51:289-295. (Pubitemid 26422976)
    • (1996) European Journal of Clinical Pharmacology , vol.51 , Issue.3-4 , pp. 289-295
    • Poulsen, L.1    Brosen, K.2    Arendt-Nielsen, L.3    Gram, L.F.4    Elbaek, K.5    Sindrup, S.H.6
  • 58
    • 0031413420 scopus 로고    scopus 로고
    • Quantification of the O- And N-demethylated and the glucuronidated metabolites of codeine relative to the debrisoquine metabolic ratio in urine in ultrarapid, rapid, and poor debrisoquine hydroxylators
    • DOI 10.1097/00007691-199710000-00010
    • Yue QY, Alm C, Svensson JO, Sawe J. Quantification of the O- and Ndemethylated and the glucuronidated metabolites of codeine relative to the debrisoquine metabolic ratio in urine in ultrarapid, rapid, and poor debrisoquine hydroxylators. Ther Drug Monit. 1997;19:539-542. (Pubitemid 28116832)
    • (1997) Therapeutic Drug Monitoring , vol.19 , Issue.5 , pp. 539-542
    • Yue, Q.Y.1    Alm, C.2    Svensson, J.O.3    Sawe, J.4
  • 59
    • 2342562985 scopus 로고    scopus 로고
    • Cytochrome P-450 2D6*10 C188T polymorphism is associated with antipsychotic-induced persistent tardive dyskinesia in Chinese schizophrenic patients
    • Liou YJ, Wang YC, Bai YM, et al. Cytochrome P-450 2D6*10 C188T polymorphism is associated with antipsychotic-induced persistent tardive dyskinesia in Chinese schizophrenic patients. Neuropsychobiology. 2004; 49:167-173.
    • (2004) Neuropsychobiology , vol.49 , pp. 167-173
    • Liou, Y.J.1    Wang, Y.C.2    Bai, Y.M.3
  • 61
    • 3142519666 scopus 로고    scopus 로고
    • Pharmacogenetics of antidepressants and antipsychotics: The contribution of allelic variations to the phenotype of drug response
    • DOI 10.1038/sj.mp.4001494
    • Kirchheiner J, Nickchen K, Bauer M, et al. Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response. Mol Psychiatry. 2004;9:442-473. (Pubitemid 38903502)
    • (2004) Molecular Psychiatry , vol.9 , Issue.5 , pp. 442-473
    • Kirchheiner, J.1    Nickchen, K.2    Bauer, M.3    Wong, M.-L.4    Licinio, J.5    Roots, I.6    Brockmoller, J.7


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