-
1
-
-
27944459717
-
SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation
-
Ahuja, D., M. T. Saenz-Robles, and J. M. Pipas. 2005. SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation. Oncogene 24:7729-7745.
-
(2005)
Oncogene
, vol.24
, pp. 7729-7745
-
-
Ahuja, D.1
Saenz-Robles, M.T.2
Pipas, J.M.3
-
2
-
-
0029854273
-
Use of normal and transgenic mice to examine the relationship between terminal differentiation of intestinal epithelial cells and accumulation of their cell cycle regulators
-
Chandrasekaran, C., C. M. Coopersmith, and J. I. Gordon. 1996. Use of normal and transgenic mice to examine the relationship between terminal differentiation of intestinal epithelial cells and accumulation of their cell cycle regulators. J. Biol. Chem. 271:28414-28421.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 28414-28421
-
-
Chandrasekaran, C.1
Coopersmith, C.M.2
Gordon, J.I.3
-
3
-
-
0020532658
-
Biochemical activities of T-antigen proteins encoded by simian virus 40 A gene deletion mutants
-
Clark, R., K. Peden, J. M. Pipas, D. Nathans, and R. Tjian. 1983. Biochemical activities of T-antigen proteins encoded by simian virus 40 A gene deletion mutants. Mol. Cell. Biol. 3:220-228.
-
(1983)
Mol. Cell. Biol
, vol.3
, pp. 220-228
-
-
Clark, R.1
Peden, K.2
Pipas, J.M.3
Nathans, D.4
Tjian, R.5
-
4
-
-
0026760426
-
Requirement for a functional Rb-1 gene in murine development
-
Clarke, A. R., E. R. Maandag, M. van Roon, N. M. van der Lugt, M. van der Valk, M. L. Hooper, A. Berns, and H. te Riele. 1992. Requirement for a functional Rb-1 gene in murine development. Nature 359:328-330.
-
(1992)
Nature
, vol.359
, pp. 328-330
-
-
Clarke, A.R.1
Maandag, E.R.2
van Roon, M.3
van der Lugt, N.M.4
van der Valk, M.5
Hooper, M.L.6
Berns, A.7
te Riele, H.8
-
5
-
-
9444242683
-
Shared role of the pRB-related p130 and p107 proteins in limb development
-
Cobrinik, D., M. H. Lee, G. Hannon, G. Mulligan, R. T. Bronson, N. Dyson, E. Harlow, D. Beach, R. A. Weinberg, and T. Jacks. 1996. Shared role of the pRB-related p130 and p107 proteins in limb development. Genes Dev. 10:1633-1644.
-
(1996)
Genes Dev
, vol.10
, pp. 1633-1644
-
-
Cobrinik, D.1
Lee, M.H.2
Hannon, G.3
Mulligan, G.4
Bronson, R.T.5
Dyson, N.6
Harlow, E.7
Beach, D.8
Weinberg, R.A.9
Jacks, T.10
-
6
-
-
0023731010
-
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene
-
DeCaprio, J. A., J. W. Ludlow, J. Figge, J. Y. Shew, C. M. Huang, W. H. Lee, E. Marsilio, E. Paucha, and D. M. Livingston. 1988. SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell 54:275-283.
-
(1988)
Cell
, vol.54
, pp. 275-283
-
-
DeCaprio, J.A.1
Ludlow, J.W.2
Figge, J.3
Shew, J.Y.4
Huang, C.M.5
Lee, W.H.6
Marsilio, E.7
Paucha, E.8
Livingston, D.M.9
-
7
-
-
0037150731
-
The genetics of the E2F family of transcription factors: Shared functions and unique roles
-
DeGregori, J. 2002. The genetics of the E2F family of transcription factors: shared functions and unique roles. Biochim. Biophys. Acta 1602:131-150.
-
(2002)
Biochim. Biophys. Acta
, vol.1602
, pp. 131-150
-
-
DeGregori, J.1
-
8
-
-
0037133323
-
-
Fewell, S. W., J. M. Pipas, and J. L. Brodsky. 2002. Mutagenesis of a functional chimeric gene in yeast identifies mutations in the simian virus 40 large T antigen J domain. Proc. Natl. Acad. Sci. USA 99:2002-2007.
-
Fewell, S. W., J. M. Pipas, and J. L. Brodsky. 2002. Mutagenesis of a functional chimeric gene in yeast identifies mutations in the simian virus 40 large T antigen J domain. Proc. Natl. Acad. Sci. USA 99:2002-2007.
-
-
-
-
9
-
-
0036118368
-
Enumeration of the simian virus 40 early region elements necessary for human cell transformation
-
Hahn, W. C., S. K. Dessain, M. W. Brooks, J. E. King, B. Elenbaas, D. M. Sabatini, J. A. DeCaprio, and R. A. Weinberg. 2002. Enumeration of the simian virus 40 early region elements necessary for human cell transformation. Mol. Cell. Biol. 22:2111-2123.
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 2111-2123
-
-
Hahn, W.C.1
Dessain, S.K.2
Brooks, M.W.3
King, J.E.4
Elenbaas, B.5
Sabatini, D.M.6
DeCaprio, J.A.7
Weinberg, R.A.8
-
10
-
-
33644862798
-
The related retinoblastoma (pRb) and p130 proteins cooperate to regulate homeostasis in the intestinal epithelium
-
Haigis, K., J. Sage, J. Glickman, S. Shafer, and T. Jacks. 2006. The related retinoblastoma (pRb) and p130 proteins cooperate to regulate homeostasis in the intestinal epithelium. J. Biol. Chem. 281:638-647.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 638-647
-
-
Haigis, K.1
Sage, J.2
Glickman, J.3
Shafer, S.4
Jacks, T.5
-
11
-
-
0019401161
-
Monoclonal antibodies specific for simian virus 40 tumor antigens
-
Harlow, E., L. V. Crawford, D. C. Pim, and N. M. Williamson. 1981. Monoclonal antibodies specific for simian virus 40 tumor antigens. J. Virol. 39:861-869.
-
(1981)
J. Virol
, vol.39
, pp. 861-869
-
-
Harlow, E.1
Crawford, L.V.2
Pim, D.C.3
Williamson, N.M.4
-
12
-
-
0026636048
-
Expression of SV-40 T antigen in the small intestinal epithelium of transgenic mice results in proliferative changes in the crypt and reentry of villus-associated enterocytes into the cell cycle but has no apparent effect on cellular differentiation programs and does not cause neoplastic transformation
-
Hauft, S. M., S. H. Kim, G. H. Schmidt, S. Pease, S. Rees, S. Harris, K. A. Roth, J. R. Hansbrough, S. M. Cohn, D. J. Ahnen, et al. 1992. Expression of SV-40 T antigen in the small intestinal epithelium of transgenic mice results in proliferative changes in the crypt and reentry of villus-associated enterocytes into the cell cycle but has no apparent effect on cellular differentiation programs and does not cause neoplastic transformation. J. Cell Biol. 117: 825-839.
-
(1992)
J. Cell Biol
, vol.117
, pp. 825-839
-
-
Hauft, S.M.1
Kim, S.H.2
Schmidt, G.H.3
Pease, S.4
Rees, S.5
Harris, S.6
Roth, K.A.7
Hansbrough, J.R.8
Cohn, S.M.9
Ahnen, D.J.10
-
13
-
-
0034949169
-
Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis
-
Ishida, S., E. Huang, H. Zuzan, R. Spang, G. Leone, M. West, and J. R. Nevins. 2001. Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis. Mol. Cell. Biol. 21:4684-4699.
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 4684-4699
-
-
Ishida, S.1
Huang, E.2
Zuzan, H.3
Spang, R.4
Leone, G.5
West, M.6
Nevins, J.R.7
-
14
-
-
0026702996
-
Effects of an Rb mutation in the mouse
-
Jacks, T., A. Fazeli, E. M. Schmitt, R. T. Bronson, M. A. Goodell, and R. A. Weinberg. 1992. Effects of an Rb mutation in the mouse. Nature 359:295-300.
-
(1992)
Nature
, vol.359
, pp. 295-300
-
-
Jacks, T.1
Fazeli, A.2
Schmitt, E.M.3
Bronson, R.T.4
Goodell, M.A.5
Weinberg, R.A.6
-
16
-
-
0027535098
-
Association of p53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 T-antigen mutants bearing internal overlapping deletion mutations
-
Kierstead, T. D., and M. J. Tevethia. 1993. Association of p53 binding and immortalization of primary C57BL/6 mouse embryo fibroblasts by using simian virus 40 T-antigen mutants bearing internal overlapping deletion mutations. J. Virol. 67:1817-1829.
-
(1993)
J. Virol
, vol.67
, pp. 1817-1829
-
-
Kierstead, T.D.1
Tevethia, M.J.2
-
17
-
-
0028277921
-
Expression of wild-type and mutant simian virus 40 large tumor antigens in villus-associated enterocytes of transgenic mice
-
Kim, S. H., K. A. Roth, C. M. Coopersmith, J. M. Pipas, and J. I. Gordon. 1994. Expression of wild-type and mutant simian virus 40 large tumor antigens in villus-associated enterocytes of transgenic mice. Proc. Natl. Acad. Sci. USA 91:6914-6918.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 6914-6918
-
-
Kim, S.H.1
Roth, K.A.2
Coopersmith, C.M.3
Pipas, J.M.4
Gordon, J.I.5
-
18
-
-
0027363255
-
Transgenic mouse models that explore the multistep hypothesis of intestinal neoplasia
-
Kim, S. H., K. A. Roth, A. R. Moser, and J. I. Gordon. 1993. Transgenic mouse models that explore the multistep hypothesis of intestinal neoplasia. J. Cell Biol. 123:877-893.
-
(1993)
J. Cell Biol
, vol.123
, pp. 877-893
-
-
Kim, S.H.1
Roth, K.A.2
Moser, A.R.3
Gordon, J.I.4
-
19
-
-
0031782695
-
Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene
-
LeCouter, J. E., B. Kablar, W. R. Hardy, C. Ying, L. A. Megeney, L. L. May, and M. A. Rudnicki. 1998. Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene. Mol. Cell. Biol. 18:7455-7465.
-
(1998)
Mol. Cell. Biol
, vol.18
, pp. 7455-7465
-
-
LeCouter, J.E.1
Kablar, B.2
Hardy, W.R.3
Ying, C.4
Megeney, L.A.5
May, L.L.6
Rudnicki, M.A.7
-
20
-
-
0032433267
-
Strain-dependent embryonic lethality in mice lacking the retinoblastoma-related p130 gene
-
LeCouter, J. E., B. Kablar, P. F. Whyte, C. Ying, and M. A. Rudnicki. 1998. Strain-dependent embryonic lethality in mice lacking the retinoblastoma-related p130 gene. Development 125:4669-4679.
-
(1998)
Development
, vol.125
, pp. 4669-4679
-
-
LeCouter, J.E.1
Kablar, B.2
Whyte, P.F.3
Ying, C.4
Rudnicki, M.A.5
-
21
-
-
0026744563
-
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
-
Lee, E. Y., C. Y. Chang, N. Hu, Y. C. Wang, C. C. Lai, K. Herrup, W. H. Lee, and A. Bradley. 1992. Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature 359:288-294.
-
(1992)
Nature
, vol.359
, pp. 288-294
-
-
Lee, E.Y.1
Chang, C.Y.2
Hu, N.3
Wang, Y.C.4
Lai, C.C.5
Herrup, K.6
Lee, W.H.7
Bradley, A.8
-
22
-
-
0029736909
-
Targeted disruption of p107: Functional overlap between p107 and Rb
-
Lee, M. H., B. O. Williams, G. Mulligan, S. Mukai, R. T. Bronson, N. Dyson, E. Harlow, and T. Jacks. 1996. Targeted disruption of p107: functional overlap between p107 and Rb. Genes Dev. 10:1621-1632.
-
(1996)
Genes Dev
, vol.10
, pp. 1621-1632
-
-
Lee, M.H.1
Williams, B.O.2
Mulligan, G.3
Mukai, S.4
Bronson, R.T.5
Dyson, N.6
Harlow, E.7
Jacks, T.8
-
23
-
-
19944395197
-
Intestinal dysplasia induced by simian virus 40 T antigen is independent of p53
-
Markovics, J. A., P. A. Carroll, M. T. Saenz Robles, H. Pope, C. M. Coopersmith, and J. M. Pipas. 2005. Intestinal dysplasia induced by simian virus 40 T antigen is independent of p53. J. Virol. 79:7492-7502.
-
(2005)
J. Virol
, vol.79
, pp. 7492-7502
-
-
Markovics, J.A.1
Carroll, P.A.2
Saenz Robles, M.T.3
Pope, H.4
Coopersmith, C.M.5
Pipas, J.M.6
-
24
-
-
0026545655
-
Simian virus 40 mutants with amino-acid substitutions near the amino terminus of large T antigen
-
Peden, K. W., and J. M. Pipas. 1992. Simian virus 40 mutants with amino-acid substitutions near the amino terminus of large T antigen. Virus Genes 6:107-118.
-
(1992)
Virus Genes
, vol.6
, pp. 107-118
-
-
Peden, K.W.1
Pipas, J.M.2
-
25
-
-
0035099918
-
Role of T antigen interactions with p53 in tumorigenesis
-
Pipas, J. M., and A. J. Levine. 2001. Role of T antigen interactions with p53 in tumorigenesis. Semin. Cancer Biol. 11:23-30.
-
(2001)
Semin. Cancer Biol
, vol.11
, pp. 23-30
-
-
Pipas, J.M.1
Levine, A.J.2
-
26
-
-
0020625930
-
Mutational analysis of simian virus 40 T antigen: Isolation and characterization of mutants with deletions in the T-antigen gene
-
Pipas, J. M., K. W. C. Peden, and D. Nathans. 1983. Mutational analysis of simian virus 40 T antigen: isolation and characterization of mutants with deletions in the T-antigen gene. Mol. Cell. Biol. 3:203-213.
-
(1983)
Mol. Cell. Biol
, vol.3
, pp. 203-213
-
-
Pipas, J.M.1
Peden, K.W.C.2
Nathans, D.3
-
27
-
-
0034320192
-
Role of the amino-terminal domain of simian virus 40 early region in inducing tumors in secretin-expressing cells in transgenic mice
-
Ratineau, C., A. Ronco, and A. B. Leiter. 2000. Role of the amino-terminal domain of simian virus 40 early region in inducing tumors in secretin-expressing cells in transgenic mice. Gastroenterology 119:1305-1311.
-
(2000)
Gastroenterology
, vol.119
, pp. 1305-1311
-
-
Ratineau, C.1
Ronco, A.2
Leiter, A.B.3
-
28
-
-
0027169533
-
Eukaryotic DnaJ homologs and the specificity of Hsp70 activity
-
Silver, P. A., and J. C. Way. 1993. Eukaryotic DnaJ homologs and the specificity of Hsp70 activity. Cell 74:5-6.
-
(1993)
Cell
, vol.74
, pp. 5-6
-
-
Silver, P.A.1
Way, J.C.2
-
29
-
-
0030842474
-
-
Srinivasan, A., A. J. McClellan, J. Vartikar, I. Marks, P. Cantalupo, Y. Li, P. Whyte, K. Rundell, J. L. Brodsky, and J. M. Pipas. 1997. The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain. Mol. Cell. Biol. 17:4761-4773.
-
Srinivasan, A., A. J. McClellan, J. Vartikar, I. Marks, P. Cantalupo, Y. Li, P. Whyte, K. Rundell, J. L. Brodsky, and J. M. Pipas. 1997. The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain. Mol. Cell. Biol. 17:4761-4773.
-
-
-
-
30
-
-
0036897835
-
A revised picture of the E2F transcriptional network and RB function
-
Stevaux, O., and N. J. Dyson. 2002. A revised picture of the E2F transcriptional network and RB function. Curr. Opin. Cell Biol. 14:684-691.
-
(2002)
Curr. Opin. Cell Biol
, vol.14
, pp. 684-691
-
-
Stevaux, O.1
Dyson, N.J.2
-
31
-
-
0030794278
-
-
Stubdal, H., J. Zalvide, K. S. Campbell, C. Schweitzer, T. M. Roberts, and J. A. DeCaprio. 1997. Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen. Mol. Cell. Biol. 17:4979-4990.
-
Stubdal, H., J. Zalvide, K. S. Campbell, C. Schweitzer, T. M. Roberts, and J. A. DeCaprio. 1997. Inactivation of pRB-related proteins p130 and p107 mediated by the J domain of simian virus 40 large T antigen. Mol. Cell. Biol. 17:4979-4990.
-
-
-
-
32
-
-
1542345708
-
Simian virus 40 infection disrupts p130-E2F and p107-E2F complexes but does not perturb pRb-E2F complexes
-
Sullivan, C. S., A. E. Baker, and J. M. Pipas. 2004. Simian virus 40 infection disrupts p130-E2F and p107-E2F complexes but does not perturb pRb-E2F complexes. Virology 320:218-228.
-
(2004)
Virology
, vol.320
, pp. 218-228
-
-
Sullivan, C.S.1
Baker, A.E.2
Pipas, J.M.3
-
33
-
-
0033842443
-
The molecular chaperone activity of simian virus 40 large T antigen is required to disrupt Rb-E2F family complexes by an ATP-dependent mechanism
-
Sullivan, C. S., P. Cantalupo, and J. M. Pipas. 2000. The molecular chaperone activity of simian virus 40 large T antigen is required to disrupt Rb-E2F family complexes by an ATP-dependent mechanism. Mol. Cell. Biol. 20:6233-6243.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 6233-6243
-
-
Sullivan, C.S.1
Cantalupo, P.2
Pipas, J.M.3
-
34
-
-
0035132831
-
ATP-dependent simian virus 40 T-antigen-Hsc70 complex formation
-
Sullivan, C. S., S. P. Gilbert, and J. M. Pipas. 2001. ATP-dependent simian virus 40 T-antigen-Hsc70 complex formation. J. Virol. 75:1601-1610.
-
(2001)
J. Virol
, vol.75
, pp. 1601-1610
-
-
Sullivan, C.S.1
Gilbert, S.P.2
Pipas, J.M.3
-
35
-
-
0033929731
-
-
Sullivan, C. S., J. D. Tremblay, S. W. Fewell, J. A. Lewis, J. L. Brodsky, and J. M. Pipas. 2000. Species-specific elements in the large T-antigen J domain are required for cellular transformation and DNA replication by simian virus 40. Mol. Cell. Biol. 20:5749-5757.
-
Sullivan, C. S., J. D. Tremblay, S. W. Fewell, J. A. Lewis, J. L. Brodsky, and J. M. Pipas. 2000. Species-specific elements in the large T-antigen J domain are required for cellular transformation and DNA replication by simian virus 40. Mol. Cell. Biol. 20:5749-5757.
-
-
-
-
36
-
-
0027269675
-
Use of transgenic mice reveals cell-specific transformation by a simian virus 40 T-antigen amino-terminal mutant
-
Symonds, H. S., S. A. McCarthy, J. Chen, J. M. Pipas, and T. Van Dyke. 1993. Use of transgenic mice reveals cell-specific transformation by a simian virus 40 T-antigen amino-terminal mutant. Mol. Cell. Biol. 13:3255-3265.
-
(1993)
Mol. Cell. Biol
, vol.13
, pp. 3255-3265
-
-
Symonds, H.S.1
McCarthy, S.A.2
Chen, J.3
Pipas, J.M.4
Van Dyke, T.5
-
37
-
-
0033857983
-
Target gene specificity of E2F and pocket protein family members in living cells
-
Wells, J., K. E. Boyd, C. J. Fry, S. M. Bartley, and P. J. Farnham. 2000. Target gene specificity of E2F and pocket protein family members in living cells. Mol. Cell. Biol. 20:5797-5807.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 5797-5807
-
-
Wells, J.1
Boyd, K.E.2
Fry, C.J.3
Bartley, S.M.4
Farnham, P.J.5
-
38
-
-
0023359932
-
-
Whitehead, R. H., A. Brown, and P. S. Bhathal. 1987. A method for the isolation and culture of human colonic crypts in collagen gels. In Vitro Cell Dev. Biol 23:436-442.
-
Whitehead, R. H., A. Brown, and P. S. Bhathal. 1987. A method for the isolation and culture of human colonic crypts in collagen gels. In Vitro Cell Dev. Biol 23:436-442.
-
-
-
-
39
-
-
0029091312
-
Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation
-
Zalvide, J., and J. A. DeCaprio. 1995. Role of pRb-related proteins in simian virus 40 large-T-antigen-mediated transformation. Mol. Cell. Biol. 15:5800-5810.
-
(1995)
Mol. Cell. Biol
, vol.15
, pp. 5800-5810
-
-
Zalvide, J.1
DeCaprio, J.A.2
-
40
-
-
0031935825
-
-
Zalvide, J., H. Stubdal, and J. A. DeCaprio. 1998. The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins. Mol. Cell. Biol. 18:1408-1415.
-
Zalvide, J., H. Stubdal, and J. A. DeCaprio. 1998. The J domain of simian virus 40 large T antigen is required to functionally inactivate RB family proteins. Mol. Cell. Biol. 18:1408-1415.
-
-
-
|