Endothelin-1, but not Ang II, activates MAP kinases through c-Src-independent Ras-Raf-dependent pathways in vascular smooth muscle cells

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 27, Issue 9, 2007, Pages 1960-1967

  Yogi, A ^a,b   Callera, G E ^a   Montezano, A C I ^a   Aranha, A B ^a   Tostes, R C ^b   Schiffrin, E L ^c   Touyz, R M ^a  

^a OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

c Raf; G protein coupled receptors; MAPK; Ras; Signal transduction; Src tyrosine kinases

Indexed keywords

ANGIOTENSIN II; ENDOTHELIN 1; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; RAF PROTEIN; RAS PROTEIN; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE DISRUPTION; MOUSE; NONHUMAN; ONCOGENE SRC; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; VASCULAR SMOOTH MUSCLE; WILD TYPE;

ANGIOTENSIN II; ANIMALS; CELLS, CULTURED; ENDOTHELIN-1; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; MONOMERIC GTP-BINDING PROTEINS; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PROTEIN-TYROSINE KINASES;

EID: 34548186475     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.107.146746     Document Type: Article

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