Lipophilicity and antiproliferative activity profiling of 2-benzylidencycloalkanones

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 856, Issue 1-2, 2007, Pages 148-155

  Hallgas, Balázs ^a   Dobos, Zsófia ^a   Agócs, Attila ^b   Idei, Miklós ^a   Kéri, György ^a   Loránd, Tamás ^b   Mészáros, György ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b UNIVERSITY OF PÉCS   (Hungary)

Author keywords

Antiproliferative screening; CLOGP calculation; Cycloalkanone; Drug likeness; Lipophilicity; Molecular library; QSAR; Retention factor

Indexed keywords

ANTIPROLIFERATIVE SCREENING; CLOGP CALCULATION; CYCLOALKANONE; LIPOPHILICITY; MOLECULAR LIBRARY; RETENTION FACTOR;

CYTOTOXICITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MOLECULAR STRUCTURE;

DRUG PRODUCTS;

2 BENZYLIDENCYCLOALKANONE DERIVATIVE; ANTINEOPLASTIC AGENT; KETONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG DESIGN; DRUG POTENCY; HUMAN; HUMAN CELL; LIPOPHILICITY; MITOSIS INHIBITION; MOLECULE; PHARMACODYNAMICS; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA;

ALKANES; CELL PROLIFERATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; LIPIDS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 34548154770     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.05.027     Document Type: Article

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