Structure-activity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1- yl)-4-aryl-1-piperazinehexanamides, a class of 5-HT7 receptor agents. 2

Journal of Medicinal Chemistry

Volumn 50, Issue 17, 2007, Pages 4214-4221

  Leopoldo, Marcello ^a   Lacivita, Enza ^a   Contino, Marialessandra ^a   Colabufo, Nicola A ^a   Berardi, Francesco ^a   Perrone, Roberto ^a  

^a UNIVERSITY OF BARI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3 [2 [2 (4 METHYL 1 PIPERIDINYL)ETHYL] 1 PYRROLIDINESULFONYL]PHENOL; 3,N DIMETHYL N [1 METHYL 3 (4 METHYL 1 PIPERIDINYL)PROPYL]BENZENESULFONAMIDE; 4 (2 DIMETHYLAMINOPHENYL) N (1,2,3,4 TETRAHYDRONAPHTHALEN 1 YL) 1 PIPERAZINEHEXANAMIDE; 4 (2 DIPHENYL) N (1,2,3,4 TETRAHYDRONAPHTHALEN 1 YL) 1 PIPERAZINEHEXANAMIDE; 4 [2 (1 METHYLETHYL)PHENYL] N (1,2,3,4 TETRAHYDRONAPHTHALEN 1 YL) 1 PIPERAZINEHEXANAMIDE; AMIDE; AS 19; DOPAMINE 2 RECEPTOR; DR 4004; PIPERAZINE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 7 RECEPTOR; SEROTONIN AGONIST; TETRALIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; GUINEA PIG; HUMAN; HUMAN CELL; LIPOPHILICITY; MALE; NONHUMAN; RADIOASSAY; RAT; RECEPTOR AFFINITY; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION;

AMIDES; ANIMALS; CELL LINE; GUINEA PIGS; HUMANS; ILEUM; MALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; PIPERAZINES; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDRONAPHTHALENES;

EID: 34548136081     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm070487n     Document Type: Article

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