Effects of a 5-HT7 receptor antagonist DR4004 on the exploratory behavior in a novel environment and on brain monoamine dynamics in mice

European Journal of Pharmacology

Volumn 518, Issue 1, 2005, Pages 30-39

  Takeda, Hiroshi ^a   Tsuji, Minoru ^a   Ikoshi, Hideaki ^a   Yamada, Tomoko ^a   Masuya, Jiro ^a   Iimori, Makio ^a   Matsumiya, Teruhiko ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

(Mouse); 5 HT7 (5 hydroxytryptamine7) receptors; Amygdala; Exploratory behavior; Hole board test; Monoamines

Indexed keywords

2A [4 (4 PHENYL 1,2,3,6 TETRAHYDROPYRIDYL)BUTYL] 2A,3,4,5 TETRAHYDROBENZ[C,D]INDOL 2(1H) ONE; DOPAMINE; DOPAMINE 1 RECEPTOR BLOCKING AGENT; DR 4004; RECEPTOR BLOCKING AGENT; SEROTONIN; SEROTONIN 7 RECEPTOR ANTAGONIST; SEROTONIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG; VANOXERINE; (1 (2 (BIS(4 FLUOROPHENYL)METHOXY)ETHYL) 4 (3 HYDROXY 3 PHENYLPROPYL) PIPERAZINYL DECANOATE); (1-(2-(BIS(4-FLUOROPHENYL)METHOXY)ETHYL)-4-(3-HYDROXY-3-PHENYLPROPYL) PIPERAZINYL DECANOATE); 2A (4 (4 PHENYL 1,2,3,6 TETRAHYDROPYRIDYL)BUTYL) 2A,3,4,5 TETRAHYDROBENZO(CD)INDOL 2(1H) ONE; 2A-(4-(4-PHENYL-1,2,3,6-TETRAHYDROPYRIDYL)BUTYL)-2A,3,4,5-TETRAHYDROBENZO(CD)INDOL-2(1H)-ONE; BIOGENIC AMINE; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; DOPAMINE UPTAKE INHIBITOR; FLUVOXAMINE; INDOLE DERIVATIVE; PIPERAZINE DERIVATIVE; PYRIDINE DERIVATIVE; SEROTONIN 7 RECEPTOR; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR; SULPIRIDE;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DRUG EFFECT; EMOTION; EXPLORATORY BEHAVIOR; LINEAR REGRESSION ANALYSIS; LOCOMOTION; MALE; MOTOR ACTIVITY; MOUSE; NEUROCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; ANIMAL; COMPARATIVE STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG INTERACTION; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; PHYSIOLOGY; TIME;

AMYGDALA; ANIMALS; BIOGENIC MONOAMINES; BRAIN; DOPAMINE; DOPAMINE ANTAGONISTS; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EXPLORATORY BEHAVIOR; FLUVOXAMINE; INDOLES; MALE; MICE; MICE, INBRED ICR; MOTOR ACTIVITY; PIPERAZINES; PYRIDINES; RECEPTORS, DOPAMINE D2; RECEPTORS, SEROTONIN; SEROTONIN; SEROTONIN ANTAGONISTS; SEROTONIN UPTAKE INHIBITORS; SULPIRIDE; TIME FACTORS;

EID: 22044437414     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.06.012     Document Type: Article

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