PSF is an IbeA-binding protein contributing to meningitic Escherichia coli K1 invasion of human brain microvascular endothelial cells

Medical Microbiology and Immunology

Volumn 196, Issue 3, 2007, Pages 135-143

  Zou, Yanming ^a   He, Lina ^a   Wu, Chun Hua ^a   Cao, Hong ^b   Xie, Zhi Hua ^c   Ouyang, Yannan ^a   Wang, Yang ^a   Jong, Ambrose ^a   Huang, Sheng He ^a,b,d  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

^c ProteinX Lab   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Brain microvascular endothelial cells; E. coli K1; IbeA; Meningitis; PSF

Indexed keywords

BINDING PROTEIN; IBEA BINDING PROTEIN; MEMBRANE PROTEIN; POLYPYRIMIDINE TRACT BINDING PROTEIN; POLYPYRIMIDINE TRACT BINDING PROTEIN ASSOCIATED SPLICING FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CELL INVASION; CELL SURFACE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENDOTHELIUM CELL; ESCHERICHIA COLI; IMMUNOFLUORESCENCE MICROSCOPY; LENTIVIRINAE; MENINGITIS; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PURIFICATION; WESTERN BLOTTING;

AMINO ACID SEQUENCE; BLOOD-BRAIN BARRIER; BRAIN; CELL LINE; ENDOTHELIAL CELLS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HUMANS; MEMBRANE PROTEINS; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RNA-BINDING PROTEINS;

EID: 34548127017     PISSN: 03008584     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00430-006-0034-x     Document Type: Article

References (37)

1. Akhmedov AT, Lopez BS (2000) Human 100-kDa homologous DNA-pairing protein is the splicing factor PSF and promotes DNA strand invasion. Nucleic Acids Res 28:3022-3030
2. Badger JL, Wass CA, Weissman SJ, Kim KS (2000) Application of signature-tagged mutagenesis for identification of Escherichia coli K1 genes that contribute to invasion of human brain microvascular endothelial cells. Infect Immun 68:5056-5061
3. Bladen CL, Udayakumar D, Takeda Y, Dynan WS (2005) Identification of the polypyrimidine tract binding protein-associated splicing factor p54(nrb) complex as a candidate DNA double-strand break rejoining factor. J Biol Chem 280:5205-5210
4. Bonacorsi S, Clermont O, Houdouin W, Cordevant C, Brahimi N, Marecat A, Tinsley C, Nassif X, Lange M, Bingen E (2003) Molecular analysis and experimental virulence of french and North American Escherichia coli neonatal meningitis isolates: Identification of a new virulent clone. J Infect Dis 187:1895-1906
5. Braun L, Ghebrehiwet B, Cossart P (2000) gC1q-R/p32, a C1q-binding protein, is a receptor for the InlB invasion protein of Listeria monocytogenes. EMBO J 19:1458-1466
6. Chen M, Li W, Fan J, Kasahara N, Woodley D (2003) An efficient gene transduction system for studying gene function in primary human dermal fibroblasts and epidermal keratinocytes. Clin Exp Dermatol 28:193-199
7. Chen YH, Chen SHM, Jong A, Zhou ZY, Li W, Suzuki K, Huang SH (2002) Enhanced Escherichia coli invasion of human brain microvascular endothelial cells is associated with alternations in cytoskeleton induced by nicotine. Cell Microbiol 4:503-514
8. Chung JW, Hong SJ, Kim KJ, Goti D, Stins MF, Shin S, Dawson VL, Dawson TM, Kim KS (2003) 37-kDa laminin receptor precursor modulates cytotoxic necrotizing factor 1-mediated RhoA activation and bacterial uptake. J Biol Chem 278:16857-16862
9. Dye BT, Patton JG (2001) An RNA recognition motif (RRM) is required for the localization of PTB-associated splicing factor (PSF) to subnuclear speckles. Exp Cell Res 263:131-144
10. Gower HJ, Moore SE, Dickson G, Elsom VL, Nayak R, Walsh FS (1989) Cloning and characterization of a myoblast cell-surface antigen defined by 24.1D5 monoclonal-antibody. Development 105:723-731
11. Hoffman JA, Badger JL, Zhang Y, Huang SH, Kim KS (2000) Escherichia coli K1 aslA contributes to invasion of brain microvascular endothelial cells in vitro and in vivo. Infect Immun 68:5062-5067
12. Huang SH, Chen YH, Fu Q, Stins M, Wang Y, Wass C, Kim KS (1999) Identification and characterization of an Escherichia coli invasion gene locus, ibeB, required for penetration of brain microvascular endothelial cells. Infect Immun 67:2103-2109
13. Huang SH, Jong AY (2001) Cellular mechanisms of microbial proteins contributing to invasion of the blood-brain barrier. Cell Microbiol 3:277-287
14. Huang SH, Stins MF, Kim KS (2000) Bacterial penetration across the blood-brain barrier during the development of neonatal meningitis. Microb Infect 2:1237-1244
15. Huang SH, Wan ZS, Chen YH, Jong AY, Kim KS (2001) Further characterization of Escherichia coli brain microvascular endothelial cell invasion gene ibeA by deletion, complementation, and protein expression. J Infect Dis 183:1071-1078
16. Kim KJ, Chung JW, Kim KS (2005) 67-kDa laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing Escherichia coli K1 into human brain microvascular endothelial cells. J Biol Chem 280:1360-1368
17. Kim KS (2003) Pathogenesis of bacterial meningitis: from bacteraemia to neuronal injury. Nat Rev Neurosci 4:376-385
18. Kim KS, Itabashi H, Gemski P, Sadoff J, Warren RL, Cross AS (1992) The K1 capsule is the critical determinant in the development of Escherichia coli meningitis in the rat. J Clin Invest 90:897-905
19. Patton JG, Porro EB, Galceran J, Tempst P, Nadalginard B (1993) Cloning and characterization of PSF, a novel premessenger RNA splicing factor. Gen Develop 7:393-406
20. Peng R, Dye BT, Perez I, Barnard DC, Thompson AB, Patton JG (2002) PSF and p54(nrb) bind a conserved stem in U5 snRNA. RNA 8:1334-1347
21. Prasadarao NV, Srivastava PK, Rudrabhatla RS, Kim KS, Huang SH, Sukumaran SK (2003) Cloning and expression of the Escherichia coli K1 outer membrane protein A receptor, a gp96 homologue. Infect Immun 71:1680-1688
22. Prasadarao NV, Wass CA, Hacker J, Jann K, Kim KS (1993) Adhesion of S-fimbriated Escherichia coli to brain glycolipids mediated by SfaA gene-encoded protein of S-fimbriae. J Biol Chem 268:10356-10363
23. Prasadarao NV, Wass CA, Kim KS (1997) Identification and characterization of S Fimbria-binding sialoglycoproteins on brain microvascular endothelial cells. Infect Immun 65:2852-2860
24. Prasadarao NV, Wass CA, Stins MF, Shimada H, Kim KS (1999) Outer membrane protein A-promoted actin condensation of brain microvascular endothelial cells is required for Escherichia coli invasion. Infect Immun 67:5775-5783
25. Rosenberger U, Lehmann I, Weise C, Franke P, Hucho F, Buchner K (2002) Identification of PSF as a protein kinase C alpha-binding protein in the cell nucleus. J Cell Biochem 86:394-402
26. Shav-Tal Y, Cohen M, Lapter S, Dye B, Patton JG, Vandekerckhove J, Zipori D (2001) Nuclear relocalization of the pre-mRNA splicing factor PSF during apoptosis involves hyperphosphorylation, masking of antigenic epitopes, and changes in protein interactions. Mol Biol Cell 12:2328-2340
27. Shav-Tal Y, Zipori D (2002) PSF and p54(nrb)/NonO-multi-functional nuclear proteins. FEBS Lett 531:109-114
28. Sinclair JF, O'Brien AD (2002) Cell surface-localized nucleolin is a eukaryotic receptor for the adhesin intimin-gamma of enterohemorrhagic Escherichia coli O157 : H7. J Biol Chem 277:2876-2885
29. Srivastava M, Pollard HB (1999) Molecular dissection of nucleolin's role in growth and cell proliferation: new insights. FASEB J 13:1911-1922
30. Stins MF, Prasadarao NV, Ibric L, Wass CA, Luckett P, Kim KS (1994) Binding characteristics of S-fimbriated Escherichia coli to isolated brain microvascular endothelial cells. Am J Pathol 145:1228-1236
31. Straub T, Grue P, Uhse A, Lisby M, Knudsen BR, Tange TO, Westergaard O, Boege F (1998) The RNA-splicing factor PSF/p54(nrb) controls DNA-topoisomerase I activity by a direct interaction. J Biol Chem 273:26261-26264
32. Wang Y (2002) The function of OmpA in Escherichia coli. Biochem Biophys Res Commun 292:396-401
33. Wang Y, Huang SH, Wass CA, Stins MF, Kim KS (1999) The gene locus yijP contributes to Escherichia coli K1 invasion of brain microvascular endothelial cells. Infect Immun 67:4751-4756
34. Watt S, Lanotte P, Mereghetti L, Moulin-Schouleur M, Picard B, Quentin R (2003) Escherichia coli strains from pregnant women and neonates: intraspecies genetic distribution and prevalence of virulence factors. J Clin Microbiol 41:1929-1935
35. Weiser JN, Gotschlich EC (1991) Outer membrane protein A (OmpA) contributes to serum resistance and pathogenicity of Escherichia coli K-1. Infect Immun 59:2252-2258
36. Zhang JR, Tuomanen E (1999) Molecular and cellular mechanisms for microbial entry into the CNS. J Neurovirol 5:591-603
37. Zolotukhin AS, Michalowski D, Bear J, Smulevitch SV, Traish AM, Peng R, Patton J, Shatsky IN, Felber BK (2003) PSF acts through the human immunodeficiency virus type 1 mRNA instability elements to regulate virus expression. Mol Cell Biol 23:6618-6630