Escherichia coli K1 aslA contributes to invasion of brain microvascular endothelial cells in vitro and in vivo

Infection and Immunity

Volumn 68, Issue 9, 2000, Pages 5062-5067

  Hoffman, J A ^a   Badger, J L ^a   Zhang, Y ^a   Huang, S H ^a   Kim, K S ^a  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL MENINGITIS; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; BLOOD BRAIN BARRIER; CEREBROSPINAL FLUID; DELETION MUTANT; DNA FLANKING REGION; ENDOTHELIUM CELL; ESCHERICHIA COLI; GENE DISRUPTION; GENETIC COMPLEMENTATION; MOLECULAR CLONING; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; TRANSPOSON;

AMINO ACID SEQUENCE; ARYLSULFATASES; BASE SEQUENCE; BRAIN; CELLS, CULTURED; CHROMOSOME MAPPING; DNA TRANSPOSABLE ELEMENTS; ENDOTHELIUM, VASCULAR; ESCHERICHIA COLI; GENES, BACTERIAL; GENETIC COMPLEMENTATION TEST; HUMANS; INFANT; MOLECULAR SEQUENCE DATA; VIRULENCE;

EID: 0033849911     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.9.5062-5067.2000     Document Type: Article

References (51)

1. Derepression of arylsulfatase synthesis in Aerobacter aerogenes by tyramine
2. Pedigrees of some mutant strains of Escherichia coli K-12
3. Environmental growth conditions influence the ability of Escherichia coli K1 to invade brain microvascular endothelial cells and confer serum resistance
4. Expression of invasin and motility are coordinately regulated in Yersinia enterocolitica
5. Identification of Escherichia coli K1 genes contributing to human brain microvascular endothelial cell (HBMEC) invasion by differential fluorescence induction (DFI)
6. Purification and characterization of the arylsulfatase synthesized by Pseudomonas aerogenosa PAO during growth in sulfate-free medium and cloning of the arylsulfatase gene (atsA)
7. The PROSITE database, its status in 1997
8. Virulence patterns of Escherichia coli K1 strains associated with neonatal meningitis
9. Structure of a human lysosomal sulfatase
10. Network protein sequence analysis
11. Structure and expression of the gene encoding the periplasmic arylsulfatase of Chlamydomonas reinhardtii
12. Posttranslational formation of formylglycine in prokaryotic sulfatases by modification of either cysteine or serine
13. Sequence determinants directing conversion of cysteine to formylglycine in eukaryotic sulfatases
14. Neonatal Escherichia coli septicemia - Bacterial counts in blood
15. A cluster of sulfatase genes on Xp22.3: Mutations in chondrodysplasia punctata (CDPX) and implications for warfarin embryopathy
16. Site-directed mutagenesis by overlap extension using the polymerase chain reaction
17. The capsule supports survival but not traversal of Escherichia coli K1 across the blood-brain barrier
18. Escherichia coli invasion of brain microvascular endothelial cells in vitro and in vivo: Molecular cloning and characterization of invasion gene ibe10
19. Identification and characterization of an Escherichia coli invasion gene locus, ibeB, required for penetration of brain microvascular endothelial cells
20. Comparison of cefotaxime, imipenem-cilastatin, ampicillin-gentamicin, and ampicillin-chloramphenicol in the treatment experimental Escherichia coli bacteremia and meningitis
21. The K1 capsule is the critical determinant in the development of Escherichia coli meningitis in the rat
22. + mutant
23. The detection and classification of membrane-spanning proteins
24. Crystal structure of human arylsulfatase A: The aldehyde function and the metal ion at the active site suggest a novel mechanism for sulfate ester hydrolysis
25. Secretion of hybrid proteins by the Yersinia Yop export system
26. Arylsulfatase from Klebsiella pneumoniae carries a formylglycine generated from a serine
27. Genetic mapping of tyramine oxidass and arylsulfatase genes and their regulation in intergenic hybrids of enteric bacteria
28. A sulfur- and tyramine-regulated Klebsiella aerogenes operon containing the arylsulfatase (atsA) gene and the atsB gene
29. Immunological study of the regulation of cellular arylsulfatase synthesis in Klebsiella aerogenes
30. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites
31. Growth phase and low pH affect the thermal regulation of the Yersinia enterocolitica inv gene
32. Phylogenetic conservation of arylsulfatases. cDNA cloning and expression of human arylsulfatase B
33. Adhesion of S-fimbriated Escherichia coli to brain glycolipids mediated by sfaA gene-encoded protein of S-fimbriae
34. Identification and characterization of a novel Ibe 10 binding protein that contributes to Escherichia coli invasion of brain microvascular endothelial cells
35. Endothelial cell GIcNAcβ1-4GlcNAc epitopes for outer membrane protein A enhance traversal of Escherichia coli across the blood-brain barrier
36. Outer membrane protein A of Escherichia coli contributes to invasion of brain microvascular endothelial cells
37. Sulfatases, trapping of the sulfated enzyme intermediate by substituting the active site formylglycine
38. DNA sequencing with chain-terminating inhibitors
39. Computational analysis of bacterial sulfatases and their modifying enzymes
40. A novel amino acid modification in sulfatases that is defective in multiple sulfatase deficiency
41. The evolutionary conservation of a novel of a protein modification, the conversion of cysteine to serinesemialdehyde in arylsulfatase from Volvox carteri
42. A broad host range mobilization system for in vivo genetic engineering: Transposon mutagenesis in gram negative bacteria
43. Cloning and expression of human arylsulfatase A
44. Binding characteristics of S fimbriated Escherichia coli to isolated brain microvascular endothelial cells
45. The iron sulfur protein AtsB is required for posttranslational formation of formylglycine in the Klebsiella sulfatase
46. Amino acid residues forming the active site of arylsulfatase A
47. The gene locus yijP contributes to Escherichia coli K1 invasion of brain microvascular endothelial cells
48. Outer membrane protein A (OmpA) contributes to serum resistance and pathogenicity of Escherichia coli K-1
49. Hunter syndrome: Isolation of an iduronate-2-sulfatase cDNA clone and analysis of patient DNA
50. Comparative immunological studies on arylsulfatase in bacteria of the family Enterobacteriaceae: Occurrence of latent arylsulfatase protein regulated by sulfur compounds and tyramine