메뉴 건너뛰기




Volumn 11, Issue 3, 2007, Pages 641-662

Cancer Chemotherapy I: Hepatocellular Injury

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; AMINOTRANSFERASE; ANTINEOPLASTIC AGENT; AZATHIOPRINE; BILIRUBIN; BLEOMYCIN; BUSULFAN; CARBOPLATIN; CARMUSTINE; CHLORAMBUCIL; CISPLATIN; CLOFARABINE; CYCLOPHOSPHAMIDE; DOXORUBICIN; ETOPOSIDE; FLOXURIDINE; FLUDARABINE; FLUOROURACIL; IRINOTECAN; MELPHALAN; MITOMYCIN C; MITOXANTRONE; PENTOSTATIN; PLANT EXTRACT; PROCARBAZINE; STREPTOZOCIN; THYMOCYTE ANTIBODY; TOPOTECAN; UNCLASSIFIED DRUG; UNINDEXED DRUG; XANTHORRHIZA EXTRACT;

EID: 34548116583     PISSN: 10893261     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cld.2007.06.007     Document Type: Review
Times cited : (24)

References (176)
  • 1
    • 0021321214 scopus 로고
    • Intestinal and liver toxicity of antineoplastic drugs
    • McDonald G.B., and Tirumali N. Intestinal and liver toxicity of antineoplastic drugs. West J Med 140 (1984) 250-259
    • (1984) West J Med , vol.140 , pp. 250-259
    • McDonald, G.B.1    Tirumali, N.2
  • 2
    • 0028817867 scopus 로고
    • Drug-induced hepatotoxicity
    • Lee W.M. Drug-induced hepatotoxicity. N Engl J Med 333 (1995) 1118-1127
    • (1995) N Engl J Med , vol.333 , pp. 1118-1127
    • Lee, W.M.1
  • 3
    • 32644469104 scopus 로고    scopus 로고
    • Drug-related hepatotoxicity
    • Navarro V.J., and Senior J.R. Drug-related hepatotoxicity. N Engl J Med 354 (2006) 731-739
    • (2006) N Engl J Med , vol.354 , pp. 731-739
    • Navarro, V.J.1    Senior, J.R.2
  • 4
    • 1542327565 scopus 로고    scopus 로고
    • Drug-induced liver injury
    • Kaplowitz N. Drug-induced liver injury. Clin Infect Dis 38 2 (2004) S44-S48
    • (2004) Clin Infect Dis , vol.38 , Issue.2
    • Kaplowitz, N.1
  • 5
    • 22944471145 scopus 로고    scopus 로고
    • Cancer chemotherapy and drug metabolism
    • Riddick D.S., Lee C., Ramji S., et al. Cancer chemotherapy and drug metabolism. Drug Metab Dispos 33 8 (2005) 1083-1096
    • (2005) Drug Metab Dispos , vol.33 , Issue.8 , pp. 1083-1096
    • Riddick, D.S.1    Lee, C.2    Ramji, S.3
  • 6
    • 0029549647 scopus 로고
    • Hepatotoxicity of chemotherapy and oncologic agents
    • King P.D., and Perry M.C. Hepatotoxicity of chemotherapy and oncologic agents. Gastroenterol Clin North Am 24 4 (1995) 969-990
    • (1995) Gastroenterol Clin North Am , vol.24 , Issue.4 , pp. 969-990
    • King, P.D.1    Perry, M.C.2
  • 7
    • 0017361298 scopus 로고
    • The nephrogenic hepatic dysfunction syndrome: a review
    • Strickland R.C., and Schenker S. The nephrogenic hepatic dysfunction syndrome: a review. Dig Dis 22 (1977) 49-55
    • (1977) Dig Dis , vol.22 , pp. 49-55
    • Strickland, R.C.1    Schenker, S.2
  • 8
    • 34548118450 scopus 로고
    • Reactivation of chronic hepatitis B virus infection after discontinuation of low dose methotrexate therapy
    • Hoofnagle J.H., Dusheiko G.M., Schafer D.F., et al. Reactivation of chronic hepatitis B virus infection after discontinuation of low dose methotrexate therapy. Ann Intern Med 112 (1990) 381-382
    • (1990) Ann Intern Med , vol.112 , pp. 381-382
    • Hoofnagle, J.H.1    Dusheiko, G.M.2    Schafer, D.F.3
  • 9
    • 0021926857 scopus 로고
    • Massive hepatic necrosis after chemotherapy withdrawal in a hepatitis B virus carrier
    • Thung S.N., Gerber M.A., Klion F., et al. Massive hepatic necrosis after chemotherapy withdrawal in a hepatitis B virus carrier. Arch Intern Med 145 (1985) 1313-1314
    • (1985) Arch Intern Med , vol.145 , pp. 1313-1314
    • Thung, S.N.1    Gerber, M.A.2    Klion, F.3
  • 10
    • 0030753864 scopus 로고    scopus 로고
    • Xenobiotic-induced hepatotoxicity: mechanisms of liver injury and methods of monitoring hepatic function
    • Sturgill M., and Lambert G. Xenobiotic-induced hepatotoxicity: mechanisms of liver injury and methods of monitoring hepatic function. Clin Chem 43 8 (1997) 1512-1526
    • (1997) Clin Chem , vol.43 , Issue.8 , pp. 1512-1526
    • Sturgill, M.1    Lambert, G.2
  • 11
    • 0025637728 scopus 로고
    • Drug-induced allergic hepatitis
    • Pohl L.R. Drug-induced allergic hepatitis. Semin Liver Dis 10 (1990) 305-315
    • (1990) Semin Liver Dis , vol.10 , pp. 305-315
    • Pohl, L.R.1
  • 12
    • 0029127584 scopus 로고
    • Inhibition of mitochondrial beta-oxidase as a mechanism of hepatotoxicity
    • Fromenty B., and Pessayre D. Inhibition of mitochondrial beta-oxidase as a mechanism of hepatotoxicity. Pharmacol Ther 67 (1995) 101-154
    • (1995) Pharmacol Ther , vol.67 , pp. 101-154
    • Fromenty, B.1    Pessayre, D.2
  • 13
    • 0027478056 scopus 로고
    • Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: a cohort study of 355 patients
    • McDonald G.B., Hinds M.S., Fisher L.D., et al. Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation: a cohort study of 355 patients. Ann Intern Med 118 (1993) 255-267
    • (1993) Ann Intern Med , vol.118 , pp. 255-267
    • McDonald, G.B.1    Hinds, M.S.2    Fisher, L.D.3
  • 14
    • 0019210340 scopus 로고
    • An analysis of hepatic venocclusive disease and centrilobular hepatic degeneration following bone marrow transplantation
    • Shulman H.M., McDonald G.B., Matthews D., et al. An analysis of hepatic venocclusive disease and centrilobular hepatic degeneration following bone marrow transplantation. Gastroenterology 79 (1980) 1178-1191
    • (1980) Gastroenterology , vol.79 , pp. 1178-1191
    • Shulman, H.M.1    McDonald, G.B.2    Matthews, D.3
  • 15
    • 0017253557 scopus 로고
    • Liver-cell adenomas associated with use of oral contraceptives
    • Edmondson H.A., Henderson B., and Benton B. Liver-cell adenomas associated with use of oral contraceptives. N Engl J Med 294 (1976) 470-472
    • (1976) N Engl J Med , vol.294 , pp. 470-472
    • Edmondson, H.A.1    Henderson, B.2    Benton, B.3
  • 16
    • 0022514767 scopus 로고
    • Resolution of a contraceptive-steroid induced hepatic adenoma with subsequent evolution into hepatocellular carcinoma
    • Gordon S.C., Reddy K.R., Livingstone A.S., et al. Resolution of a contraceptive-steroid induced hepatic adenoma with subsequent evolution into hepatocellular carcinoma. Ann Intern Med 105 (1986) 547-549
    • (1986) Ann Intern Med , vol.105 , pp. 547-549
    • Gordon, S.C.1    Reddy, K.R.2    Livingstone, A.S.3
  • 17
    • 0017505482 scopus 로고
    • Methotrexate hepatotoxicity in children with leukemia
    • McIntosh S., Davidson D.L., O'Brien R.T., et al. Methotrexate hepatotoxicity in children with leukemia. J Pediatr 90 (1977) 1019-1021
    • (1977) J Pediatr , vol.90 , pp. 1019-1021
    • McIntosh, S.1    Davidson, D.L.2    O'Brien, R.T.3
  • 18
    • 0034884143 scopus 로고    scopus 로고
    • Liver biopsy in psoriatic arthritis to detect methotrexate hepatotoxicity
    • Grismer L.E., Gill S.A., and Harris M.D. Liver biopsy in psoriatic arthritis to detect methotrexate hepatotoxicity. J Clin Rheumatol 7 4 (2001) 224-227
    • (2001) J Clin Rheumatol , vol.7 , Issue.4 , pp. 224-227
    • Grismer, L.E.1    Gill, S.A.2    Harris, M.D.3
  • 19
    • 84967899994 scopus 로고
    • Massive hepatic necrosis after cyclophosphamide
    • Aubrey D.A. Massive hepatic necrosis after cyclophosphamide. Br Med J 3 (1970) 588
    • (1970) Br Med J , vol.3 , pp. 588
    • Aubrey, D.A.1
  • 20
    • 0027501440 scopus 로고
    • Cyclophosphamide induced hepatotoxicity in a patient with Wegener's granulomatosis
    • Snyder L.S., Heigh R.L., and Anderson M.L. Cyclophosphamide induced hepatotoxicity in a patient with Wegener's granulomatosis. Mayo Clin Proc 68 (1993) 1203-1204
    • (1993) Mayo Clin Proc , vol.68 , pp. 1203-1204
    • Snyder, L.S.1    Heigh, R.L.2    Anderson, M.L.3
  • 21
    • 0029809978 scopus 로고    scopus 로고
    • Cellular target of cyclophosphamide toxicity in the murine liver: role of glutathione and site of metabolic activation
    • DeLeve L.D. Cellular target of cyclophosphamide toxicity in the murine liver: role of glutathione and site of metabolic activation. Hepatology 24 (1996) 830-837
    • (1996) Hepatology , vol.24 , pp. 830-837
    • DeLeve, L.D.1
  • 22
    • 0026516501 scopus 로고
    • The effects of impaired liver function on the elimination of antineoplastic agents
    • Koren G., Beatty K., Seto A., et al. The effects of impaired liver function on the elimination of antineoplastic agents. Ann Pharmacother 26 3 (1992) 363-371
    • (1992) Ann Pharmacother , vol.26 , Issue.3 , pp. 363-371
    • Koren, G.1    Beatty, K.2    Seto, A.3
  • 23
    • 0034021677 scopus 로고    scopus 로고
    • The effect of busulphan on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite: time interval influence on therapeutic efficacy and therapy-related toxicity
    • Hassan M., Ljungman P., Ringden O., et al. The effect of busulphan on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite: time interval influence on therapeutic efficacy and therapy-related toxicity. Bone Marrow Transplant 25 (2000) 915-924
    • (2000) Bone Marrow Transplant , vol.25 , pp. 915-924
    • Hassan, M.1    Ljungman, P.2    Ringden, O.3
  • 24
    • 0025780243 scopus 로고
    • Regimen-related toxicity of a busulphan-cyclophosphamide conditioning regimen in 70 patients undergoing allogeneic bone marrow transplantation
    • Nevill T.J., Barnett M.J., Klingemann H.G., et al. Regimen-related toxicity of a busulphan-cyclophosphamide conditioning regimen in 70 patients undergoing allogeneic bone marrow transplantation. J Clin Oncol 9 (1991) 1224-1232
    • (1991) J Clin Oncol , vol.9 , pp. 1224-1232
    • Nevill, T.J.1    Barnett, M.J.2    Klingemann, H.G.3
  • 25
    • 0037370735 scopus 로고    scopus 로고
    • Cyclophosphamide metabolism, liver toxicity, and mortality following hematopoietic stem cell transplantation
    • McDonald G.B., Slattery J.T., Bouvier M.E., et al. Cyclophosphamide metabolism, liver toxicity, and mortality following hematopoietic stem cell transplantation. Blood 101 5 (2003) 2043-2048
    • (2003) Blood , vol.101 , Issue.5 , pp. 2043-2048
    • McDonald, G.B.1    Slattery, J.T.2    Bouvier, M.E.3
  • 26
    • 0023916531 scopus 로고
    • Cyclophosphamide induced liver necrosis: a possible interaction with azathioprine
    • Shaunak S., Munro J.M., Weinbre K., et al. Cyclophosphamide induced liver necrosis: a possible interaction with azathioprine. Q J Med 252 (1988) 309-317
    • (1988) Q J Med , vol.252 , pp. 309-317
    • Shaunak, S.1    Munro, J.M.2    Weinbre, K.3
  • 27
    • 23844446098 scopus 로고    scopus 로고
    • Kupffer cell-expressed membrane-bound TNF mediates melphalan hepatotoxicity via activation of both TNF receptors
    • Kresse M., Latta M., Kunstle G., et al. Kupffer cell-expressed membrane-bound TNF mediates melphalan hepatotoxicity via activation of both TNF receptors. J Immunol 175 (2005) 4076-4083
    • (2005) J Immunol , vol.175 , pp. 4076-4083
    • Kresse, M.1    Latta, M.2    Kunstle, G.3
  • 28
    • 0345596439 scopus 로고    scopus 로고
    • Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver
    • Alexander H.R., Bartlett D.L., Libutti S.K., et al. Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver. J Clin Oncol 16 (1998) 1479-1489
    • (1998) J Clin Oncol , vol.16 , pp. 1479-1489
    • Alexander, H.R.1    Bartlett, D.L.2    Libutti, S.K.3
  • 29
    • 0022982316 scopus 로고
    • Phase II trial of high dose melphalan and autologous bone marrow transplantation for metastatic colon carcinoma
    • Leff R.S., Thompson J.M., Johnson D.B., et al. Phase II trial of high dose melphalan and autologous bone marrow transplantation for metastatic colon carcinoma. J Clin Oncol 4 (1986) 1586-1591
    • (1986) J Clin Oncol , vol.4 , pp. 1586-1591
    • Leff, R.S.1    Thompson, J.M.2    Johnson, D.B.3
  • 30
    • 1642351377 scopus 로고    scopus 로고
    • Isolated hepatic perfusion with high-dose melphalan for the treatment of uveal melanoma metastases confined to the liver
    • Noter S.L., Rothbarth J., Pijl M.E., et al. Isolated hepatic perfusion with high-dose melphalan for the treatment of uveal melanoma metastases confined to the liver. Melanoma Res 14 (2004) 67-72
    • (2004) Melanoma Res , vol.14 , pp. 67-72
    • Noter, S.L.1    Rothbarth, J.2    Pijl, M.E.3
  • 31
    • 0038814227 scopus 로고    scopus 로고
    • Melphalan antitumor efficacy and hepatotoxicity: the effect of variable infusion duration in the hepatic artery
    • Rothbarth J., Woutersen R.A., Sparidans R.W., et al. Melphalan antitumor efficacy and hepatotoxicity: the effect of variable infusion duration in the hepatic artery. J Pharmacol Exp Ther 305 3 (2003) 1098-1103
    • (2003) J Pharmacol Exp Ther , vol.305 , Issue.3 , pp. 1098-1103
    • Rothbarth, J.1    Woutersen, R.A.2    Sparidans, R.W.3
  • 32
    • 0001152069 scopus 로고
    • Liver damage after chemotherapy for leukemia and lymphoma
    • Amromin G.D., Delman R.M., and Shanbran E. Liver damage after chemotherapy for leukemia and lymphoma. Gastroenterology 42 (1962) 401-410
    • (1962) Gastroenterology , vol.42 , pp. 401-410
    • Amromin, G.D.1    Delman, R.M.2    Shanbran, E.3
  • 33
    • 0005182981 scopus 로고
    • Hepatotoxicity due to chlorambucil. Report of a case
    • Koler R.D., and Forsgren A.L. Hepatotoxicity due to chlorambucil. Report of a case. JAMA 167 (1958) 316-317
    • (1958) JAMA , vol.167 , pp. 316-317
    • Koler, R.D.1    Forsgren, A.L.2
  • 34
    • 0019366940 scopus 로고
    • Drug-induced granulomatous hepatitis
    • McMaster K., and Hennigar G. Drug-induced granulomatous hepatitis. Lab Invest 44 (1981) 61-73
    • (1981) Lab Invest , vol.44 , pp. 61-73
    • McMaster, K.1    Hennigar, G.2
  • 35
    • 0020615123 scopus 로고
    • Depletion in vitro of mitochondrial glutathione in rat hepatocytes and enhancement of lipid peroxidation by Adriamycin and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)
    • Meredith M.J., and Reed D.J. Depletion in vitro of mitochondrial glutathione in rat hepatocytes and enhancement of lipid peroxidation by Adriamycin and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU). Biochem Pharmacol 32 8 (1983) 1383-1388
    • (1983) Biochem Pharmacol , vol.32 , Issue.8 , pp. 1383-1388
    • Meredith, M.J.1    Reed, D.J.2
  • 36
    • 0021016737 scopus 로고
    • Intensive 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), NSC #4366650 and cryopreserved autologous marrow transplantation for refractory cancer. A phase I-II study
    • Phillips G., Fay J., Herzig G., et al. Intensive 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), NSC #4366650 and cryopreserved autologous marrow transplantation for refractory cancer. A phase I-II study. Cancer 52 10 (1983) 1792-1802
    • (1983) Cancer , vol.52 , Issue.10 , pp. 1792-1802
    • Phillips, G.1    Fay, J.2    Herzig, G.3
  • 37
    • 0842330494 scopus 로고    scopus 로고
    • Hepatotoxicity associated with CCNU (Lomustine) chemotherapy in dogs
    • Kristal H., Rassnick K., et al. Hepatotoxicity associated with CCNU (Lomustine) chemotherapy in dogs. J Vet Intern Med 18 (2004) 75-80
    • (2004) J Vet Intern Med , vol.18 , pp. 75-80
    • Kristal, H.1    Rassnick, K.2
  • 38
    • 0034662050 scopus 로고    scopus 로고
    • Enhanced hepatotoxicity and toxic outcome of thioacetamide in streptozotocin-induced diabetic rats
    • Wang T., Fontenot R.D., Soni M.G., et al. Enhanced hepatotoxicity and toxic outcome of thioacetamide in streptozotocin-induced diabetic rats. Toxicol Appl Pharmacol 166 2 (2000) 92-100
    • (2000) Toxicol Appl Pharmacol , vol.166 , Issue.2 , pp. 92-100
    • Wang, T.1    Fontenot, R.D.2    Soni, M.G.3
  • 39
    • 0015644058 scopus 로고
    • Pancreatic islet cell carcinoma II: results of therapy with streptozotocin in 52 patients
    • Broder L.E., and Carter S.K. Pancreatic islet cell carcinoma II: results of therapy with streptozotocin in 52 patients. Ann Intern Med 79 (1973) 108-118
    • (1973) Ann Intern Med , vol.79 , pp. 108-118
    • Broder, L.E.1    Carter, S.K.2
  • 40
    • 0016269663 scopus 로고
    • Clinical antitumor activity and toxicity of streptozotocin (NSC-85998)
    • Schein P.S., O'Connell M.J., Blom J., et al. Clinical antitumor activity and toxicity of streptozotocin (NSC-85998). Cancer 34 (1974) 993-1000
    • (1974) Cancer , vol.34 , pp. 993-1000
    • Schein, P.S.1    O'Connell, M.J.2    Blom, J.3
  • 41
    • 0031906024 scopus 로고    scopus 로고
    • Metallothionein null mice are sensitive to cisplatin-induced hepatotoxicity
    • Liu J., Liu Y., Habeebu S., et al. Metallothionein null mice are sensitive to cisplatin-induced hepatotoxicity. Toxicol Appl Pharmacol 149 (1998) 24-31
    • (1998) Toxicol Appl Pharmacol , vol.149 , pp. 24-31
    • Liu, J.1    Liu, Y.2    Habeebu, S.3
  • 42
    • 0027238140 scopus 로고
    • Hepatotoxicity associated with cisplatin chemotherapy
    • Cersosimo R.J. Hepatotoxicity associated with cisplatin chemotherapy. Ann Pharmacother 27 (1993) 438-441
    • (1993) Ann Pharmacother , vol.27 , pp. 438-441
    • Cersosimo, R.J.1
  • 43
    • 0023293067 scopus 로고
    • Cisplatin-induced hepatic toxicity
    • Pollera C.F., Ameglio F., Nardi M., et al. Cisplatin-induced hepatic toxicity. J Clin Oncol 5 (1987) 318-319
    • (1987) J Clin Oncol , vol.5 , pp. 318-319
    • Pollera, C.F.1    Ameglio, F.2    Nardi, M.3
  • 44
    • 1942471767 scopus 로고    scopus 로고
    • Abrogation of cisplatin-induced hepatotoxicity in mice by xanthorrhizol is related to its effect on the regulation of gene transcription
    • Kim S.H., Hong K.O., Chung W.Y., et al. Abrogation of cisplatin-induced hepatotoxicity in mice by xanthorrhizol is related to its effect on the regulation of gene transcription. Toxicol Appl Pharmacol 196 (2004) 346-355
    • (2004) Toxicol Appl Pharmacol , vol.196 , pp. 346-355
    • Kim, S.H.1    Hong, K.O.2    Chung, W.Y.3
  • 45
    • 18044363456 scopus 로고    scopus 로고
    • Phosphorylation of c-Jun N-terminal Kinases (JNKs) is involved in the preventive effect of xanthorrhizol on cisplatin-induced hepatotoxicity
    • Hong K.O., Hwang J.K., Park K.K., et al. Phosphorylation of c-Jun N-terminal Kinases (JNKs) is involved in the preventive effect of xanthorrhizol on cisplatin-induced hepatotoxicity. Arch Toxicol 79 (2005) 231-236
    • (2005) Arch Toxicol , vol.79 , pp. 231-236
    • Hong, K.O.1    Hwang, J.K.2    Park, K.K.3
  • 46
    • 0035958630 scopus 로고    scopus 로고
    • Prolonged Jun N-terminal (JNK) activation and the upregulation of p53 and p21 preceded apoptosis in hepatocytes after partial hepatectomy and cisplatin
    • Kobayashi K., and Tsukamoto I. Prolonged Jun N-terminal (JNK) activation and the upregulation of p53 and p21 preceded apoptosis in hepatocytes after partial hepatectomy and cisplatin. Biochim Biophys Acta 1537 (2001) 79-88
    • (2001) Biochim Biophys Acta , vol.1537 , pp. 79-88
    • Kobayashi, K.1    Tsukamoto, I.2
  • 47
    • 27944490045 scopus 로고    scopus 로고
    • Safety profile of platinum-based chemotherapy in the treatment of advanced non-small cell lung cancer in elderly patients
    • Rossi A., Maione P., and Gridelli C. Safety profile of platinum-based chemotherapy in the treatment of advanced non-small cell lung cancer in elderly patients. Expert Opin Drug Saf 4 6 (2005) 1051-1067
    • (2005) Expert Opin Drug Saf , vol.4 , Issue.6 , pp. 1051-1067
    • Rossi, A.1    Maione, P.2    Gridelli, C.3
  • 48
    • 0025783229 scopus 로고
    • Fatal thrombocytopenia and liver failure associated with carboplatin therapy
    • Hruban R., Sternberg S.S., Meyers P., et al. Fatal thrombocytopenia and liver failure associated with carboplatin therapy. Cancer Invest 9 (1991) 263-268
    • (1991) Cancer Invest , vol.9 , pp. 263-268
    • Hruban, R.1    Sternberg, S.S.2    Meyers, P.3
  • 49
    • 0042566052 scopus 로고    scopus 로고
    • Lethal hepatic injury by combined treatment of radiation plus chemotherapy in rats with thioacetamide-induced liver cirrhosis
    • Seong J., Han K.H., Park Y.N., et al. Lethal hepatic injury by combined treatment of radiation plus chemotherapy in rats with thioacetamide-induced liver cirrhosis. Int J Radiat Oncol Biol Phys 57 1 (2003) 282-288
    • (2003) Int J Radiat Oncol Biol Phys , vol.57 , Issue.1 , pp. 282-288
    • Seong, J.1    Han, K.H.2    Park, Y.N.3
  • 50
    • 0032431253 scopus 로고    scopus 로고
    • Chronic liver failure induced by long-term administration of tegafur: a case report
    • Matsumoto M., Nakao K., Matsumoto H., et al. Chronic liver failure induced by long-term administration of tegafur: a case report. Hepatogastroenterology 45 24 (1998) 2372-2375
    • (1998) Hepatogastroenterology , vol.45 , Issue.24 , pp. 2372-2375
    • Matsumoto, M.1    Nakao, K.2    Matsumoto, H.3
  • 51
    • 9244263074 scopus 로고    scopus 로고
    • 5-fluorouracil leucovorin and oxaliplatin (FOLFOX) in the treatment of metastatic colon cancer with severe liver dysfunction
    • Fakih M.G. 5-fluorouracil leucovorin and oxaliplatin (FOLFOX) in the treatment of metastatic colon cancer with severe liver dysfunction. Oncology 67 3-4 (2004) 222-224
    • (2004) Oncology , vol.67 , Issue.3-4 , pp. 222-224
    • Fakih, M.G.1
  • 52
    • 3242673359 scopus 로고    scopus 로고
    • Successful treatment of 5-FU intraarterial infusion on the third postoperative day for a patient with multiple liver metastases from colon cancer and high risk of liver failure
    • Mori T., Munakata M., Kasai M., et al. Successful treatment of 5-FU intraarterial infusion on the third postoperative day for a patient with multiple liver metastases from colon cancer and high risk of liver failure. Gan To Kagaku Ryoho 31 7 (2004) 1101-1103
    • (2004) Gan To Kagaku Ryoho , vol.31 , Issue.7 , pp. 1101-1103
    • Mori, T.1    Munakata, M.2    Kasai, M.3
  • 53
    • 0023552654 scopus 로고
    • A prospective randomized trial of regional versus systemic continuous 5-fluorodeoxyuridine chemotherapy in the treatment of colorectal liver metastases
    • Chang A.E., Schneider P.D., Sugarbaker P.H., et al. A prospective randomized trial of regional versus systemic continuous 5-fluorodeoxyuridine chemotherapy in the treatment of colorectal liver metastases. Ann Surg 206 6 (1987) 685-693
    • (1987) Ann Surg , vol.206 , Issue.6 , pp. 685-693
    • Chang, A.E.1    Schneider, P.D.2    Sugarbaker, P.H.3
  • 54
    • 34548130894 scopus 로고
    • Biliary sclerosis in patients receiving hepatic arterial infusions of floxuridine
    • Hohn D., Melnick J., Stagg R., et al. Biliary sclerosis in patients receiving hepatic arterial infusions of floxuridine. J Clin Oncol 32 (1985) 161-169
    • (1985) J Clin Oncol , vol.32 , pp. 161-169
    • Hohn, D.1    Melnick, J.2    Stagg, R.3
  • 55
    • 0022518341 scopus 로고
    • Liver pathology following hepatic arterial infusion chemotherapy: hepatic toxicity with FUDR
    • Doria M.I., Shepard K.V., Levin B., et al. Liver pathology following hepatic arterial infusion chemotherapy: hepatic toxicity with FUDR. Cancer 58 (1986) 855-861
    • (1986) Cancer , vol.58 , pp. 855-861
    • Doria, M.I.1    Shepard, K.V.2    Levin, B.3
  • 56
  • 57
    • 0005211126 scopus 로고
    • Status of infusion chemotherapy for the treatment of liver metastases
    • Niederhuber J.E., and Grochow L.B. Status of infusion chemotherapy for the treatment of liver metastases. Princ Pract Oncol Updates 3 (1989) 1-9
    • (1989) Princ Pract Oncol Updates , vol.3 , pp. 1-9
    • Niederhuber, J.E.1    Grochow, L.B.2
  • 59
    • 0034749380 scopus 로고    scopus 로고
    • Fludarabine-based dose-reduced conditioning regimen followed by allogeneic stem cell transplantation from related or unrelated donors in patients with myelodysplastic syndrome
    • Kroger N., Schetelig J., and Zabelina T.A. Fludarabine-based dose-reduced conditioning regimen followed by allogeneic stem cell transplantation from related or unrelated donors in patients with myelodysplastic syndrome. Bone Marrow Transplant 28 7 (2001) 643-647
    • (2001) Bone Marrow Transplant , vol.28 , Issue.7 , pp. 643-647
    • Kroger, N.1    Schetelig, J.2    Zabelina, T.A.3
  • 60
    • 33750963443 scopus 로고    scopus 로고
    • The activity and toxicity of low dose clofarabine against relapsed or refractory myeloma
    • Uy G.L., Tomasson M.H., Ruddell A., et al. The activity and toxicity of low dose clofarabine against relapsed or refractory myeloma. Haematologica 91 (2006) 1581-1582
    • (2006) Haematologica , vol.91 , pp. 1581-1582
    • Uy, G.L.1    Tomasson, M.H.2    Ruddell, A.3
  • 61
    • 33746057854 scopus 로고    scopus 로고
    • Clinical and pharmacokinetic study of clofarabine in chronic lymphocytic leukemia: strategy for treatment
    • Gandhi V., Plunkett W., Bonate P.L., et al. Clinical and pharmacokinetic study of clofarabine in chronic lymphocytic leukemia: strategy for treatment. Clin Cancer Res 12 (2006) 4011-4017
    • (2006) Clin Cancer Res , vol.12 , pp. 4011-4017
    • Gandhi, V.1    Plunkett, W.2    Bonate, P.L.3
  • 62
    • 0033933650 scopus 로고    scopus 로고
    • Pentostatin in T-cell malignancies. Leukemia Cooperative Group and the European Organization for Research and Treatment of Cancer
    • Ho A.D., Suciu S., Stryckmans P., et al. Pentostatin in T-cell malignancies. Leukemia Cooperative Group and the European Organization for Research and Treatment of Cancer. Semin Oncol 27 2 (2000) 52-57
    • (2000) Semin Oncol , vol.27 , Issue.2 , pp. 52-57
    • Ho, A.D.1    Suciu, S.2    Stryckmans, P.3
  • 63
    • 0031761462 scopus 로고    scopus 로고
    • Phase I/II evaluation of Pentostatin in a five day schedule for the treatment of relapsed/refractory B-cell chronic lymphocytic leukaemia
    • Johnson S.A., Catovsky D., Child J.A., et al. Phase I/II evaluation of Pentostatin in a five day schedule for the treatment of relapsed/refractory B-cell chronic lymphocytic leukaemia. Invest New Drugs 16 2 (1998) 155-160
    • (1998) Invest New Drugs , vol.16 , Issue.2 , pp. 155-160
    • Johnson, S.A.1    Catovsky, D.2    Child, J.A.3
  • 64
    • 0019467252 scopus 로고
    • Phase I study of 2′-deoxycoformycin in acute lymphoblastic leukemia
    • Poplack D.G., Sallan S.E., Rivera G., et al. Phase I study of 2′-deoxycoformycin in acute lymphoblastic leukemia. Cancer Res 41 (1981) 3343-3346
    • (1981) Cancer Res , vol.41 , pp. 3343-3346
    • Poplack, D.G.1    Sallan, S.E.2    Rivera, G.3
  • 65
    • 0021240616 scopus 로고
    • Glutathione depletion and susceptibility
    • Reed D.J., and Frariss M.W. Glutathione depletion and susceptibility. Pharmacol Rev 36 (1984) 25-33
    • (1984) Pharmacol Rev , vol.36 , pp. 25-33
    • Reed, D.J.1    Frariss, M.W.2
  • 66
    • 0025002858 scopus 로고
    • Hepatotoxicity of mitoxantrone and doxorubicin
    • Llesuy S.F., and Arnaiz S.L. Hepatotoxicity of mitoxantrone and doxorubicin. Toxicology 63 2 (1990) 187-198
    • (1990) Toxicology , vol.63 , Issue.2 , pp. 187-198
    • Llesuy, S.F.1    Arnaiz, S.L.2
  • 67
    • 13944283745 scopus 로고    scopus 로고
    • Doxorubicin hepatotoxicity and hepatic free radical metabolism in rats. The effects of vitamin E and catechin
    • Kalender Y., Yel M., and Kalender S. Doxorubicin hepatotoxicity and hepatic free radical metabolism in rats. The effects of vitamin E and catechin. Toxicology 209 1 (2005) 39-45
    • (2005) Toxicology , vol.209 , Issue.1 , pp. 39-45
    • Kalender, Y.1    Yel, M.2    Kalender, S.3
  • 68
    • 0032195121 scopus 로고    scopus 로고
    • Protective and antioxidative effect of 2(3)tert-butyl-4-hydroxyanisole against cytotoxicity induced by doxorubicin in mice
    • Wang L., and Lin S. Protective and antioxidative effect of 2(3)tert-butyl-4-hydroxyanisole against cytotoxicity induced by doxorubicin in mice. Yao Xue Xue Bao 33 11 (1998) 807-811
    • (1998) Yao Xue Xue Bao , vol.33 , Issue.11 , pp. 807-811
    • Wang, L.1    Lin, S.2
  • 69
    • 0033962060 scopus 로고    scopus 로고
    • Metallothionein acts as a cytoprotectant against doxorubicin toxicity
    • Kimura T., Fujita I., Itoh N., et al. Metallothionein acts as a cytoprotectant against doxorubicin toxicity. J Pharmacol Exp Ther 292 1 (2000) 299-302
    • (2000) J Pharmacol Exp Ther , vol.292 , Issue.1 , pp. 299-302
    • Kimura, T.1    Fujita, I.2    Itoh, N.3
  • 70
    • 33749995779 scopus 로고    scopus 로고
    • The selective effect of cystathionine on doxorubicin hepatotoxicity in tumor-bearing mice
    • Kwiecien I., Michalska M., and Wlodek L. The selective effect of cystathionine on doxorubicin hepatotoxicity in tumor-bearing mice. Eur J Pharmacol 550 1-3 (2006) 39-46
    • (2006) Eur J Pharmacol , vol.550 , Issue.1-3 , pp. 39-46
    • Kwiecien, I.1    Michalska, M.2    Wlodek, L.3
  • 71
    • 33646263853 scopus 로고    scopus 로고
    • Effects of melatonin in reducing the toxic effects of doxorubicin
    • Oz E., and Ilhan M.N. Effects of melatonin in reducing the toxic effects of doxorubicin. Mol Cell Biochem 286 1-2 (2006) 11-15
    • (2006) Mol Cell Biochem , vol.286 , Issue.1-2 , pp. 11-15
    • Oz, E.1    Ilhan, M.N.2
  • 72
    • 0036021024 scopus 로고    scopus 로고
    • Phase II study of docetaxel and epirubicin in Chinese patients with metastatic breast cancer
    • Yeo W., Mok T.S., Tse K.K., et al. Phase II study of docetaxel and epirubicin in Chinese patients with metastatic breast cancer. Anticancer Drugs 13 6 (2002) 655-662
    • (2002) Anticancer Drugs , vol.13 , Issue.6 , pp. 655-662
    • Yeo, W.1    Mok, T.S.2    Tse, K.K.3
  • 73
    • 0031816602 scopus 로고    scopus 로고
    • Doxorubicin pharmacokinetics: the effect of abnormal liver biochemistry tests
    • Twelves C.J., Dobbs N.A., Gillies H.C., et al. Doxorubicin pharmacokinetics: the effect of abnormal liver biochemistry tests. Cancer Chemother Pharmacol 42 (1998) 229-234
    • (1998) Cancer Chemother Pharmacol , vol.42 , pp. 229-234
    • Twelves, C.J.1    Dobbs, N.A.2    Gillies, H.C.3
  • 74
    • 0026743053 scopus 로고
    • Clinical pharmacokinetics of epirubicin: the importance of liver biochemistry tests
    • Twelves C.J., Dobbs N.A., Michael Y., et al. Clinical pharmacokinetics of epirubicin: the importance of liver biochemistry tests. Br J Cancer 66 (1992) 765-769
    • (1992) Br J Cancer , vol.66 , pp. 765-769
    • Twelves, C.J.1    Dobbs, N.A.2    Michael, Y.3
  • 75
    • 0021349406 scopus 로고
    • Acute doxorubicin toxicity. Relationship to pretreatment liver function, response, and pharmacokinetics in patients with acute nonlymphocytic leukemia
    • Brenner D.E., Wiernik P.H., Wesley M., et al. Acute doxorubicin toxicity. Relationship to pretreatment liver function, response, and pharmacokinetics in patients with acute nonlymphocytic leukemia. Cancer 53 (1984) 1042-1048
    • (1984) Cancer , vol.53 , pp. 1042-1048
    • Brenner, D.E.1    Wiernik, P.H.2    Wesley, M.3
  • 76
    • 0015609611 scopus 로고
    • A clinical review of bleomycin. A new antineoplastic agent
    • Blum R.H., Carter S.K., and Agre K. A clinical review of bleomycin. A new antineoplastic agent. Cancer 31 (1973) 903-914
    • (1973) Cancer , vol.31 , pp. 903-914
    • Blum, R.H.1    Carter, S.K.2    Agre, K.3
  • 77
    • 32244439557 scopus 로고    scopus 로고
    • Hepatotoxicity of chemotherapy
    • Floyd J., Mirza I., Sachs B., et al. Hepatotoxicity of chemotherapy. Semin Oncol 33 (2006) 50-67
    • (2006) Semin Oncol , vol.33 , pp. 50-67
    • Floyd, J.1    Mirza, I.2    Sachs, B.3
  • 78
    • 0025228915 scopus 로고
    • Assessment of pulmonary and hematologic toxicities of liblomycin, a novel bleomycin analog
    • Newman R.A., Siddik Z.H., Travis E.L., et al. Assessment of pulmonary and hematologic toxicities of liblomycin, a novel bleomycin analog. Invest New Drugs 8 1 (1990) 33-41
    • (1990) Invest New Drugs , vol.8 , Issue.1 , pp. 33-41
    • Newman, R.A.1    Siddik, Z.H.2    Travis, E.L.3
  • 79
    • 23044456607 scopus 로고    scopus 로고
    • Hepatic arterial infusion of floxuridine and dexamethasone plus high-dose mitomycin C for patients with unresectable hepatic metastases from colorectal carcinoma
    • Kemeny N., Eid A., Stockman J., et al. Hepatic arterial infusion of floxuridine and dexamethasone plus high-dose mitomycin C for patients with unresectable hepatic metastases from colorectal carcinoma. J Surg Oncol 91 2 (2005) 97-101
    • (2005) J Surg Oncol , vol.91 , Issue.2 , pp. 97-101
    • Kemeny, N.1    Eid, A.2    Stockman, J.3
  • 80
    • 0030267755 scopus 로고    scopus 로고
    • Isolated liver perfusion with mitomycin C in the treatment of colorectal cancer metastases confined to the liver
    • Marinelli A., de Brauw L.M., Beerman H., et al. Isolated liver perfusion with mitomycin C in the treatment of colorectal cancer metastases confined to the liver. Jpn J Clin Oncol 26 5 (1996) 341-350
    • (1996) Jpn J Clin Oncol , vol.26 , Issue.5 , pp. 341-350
    • Marinelli, A.1    de Brauw, L.M.2    Beerman, H.3
  • 81
    • 0032422726 scopus 로고    scopus 로고
    • Practical treatment guide for dose individualization in cancer chemotherapy
    • Canal P., Chatelut E., and Guichard S. Practical treatment guide for dose individualization in cancer chemotherapy. Drugs 56 6 (1998) 1019-1038
    • (1998) Drugs , vol.56 , Issue.6 , pp. 1019-1038
    • Canal, P.1    Chatelut, E.2    Guichard, S.3
  • 82
    • 0345267790 scopus 로고
    • Complete recovery of radioactivity after administration of 14C-etoposide in man
    • [abstract]
    • Joel S.P., Hall M., Gaver R.C., et al. Complete recovery of radioactivity after administration of 14C-etoposide in man. [abstract]. Annu Meet Am Soc Clin Oncol 14 (1995) 168
    • (1995) Annu Meet Am Soc Clin Oncol , vol.14 , pp. 168
    • Joel, S.P.1    Hall, M.2    Gaver, R.C.3
  • 83
    • 0021073168 scopus 로고
    • Etoposide induced hepatic injury: a potential complication of high-dose therapy
    • Wolff S.N., Johnson D.H., Greco F.A., et al. Etoposide induced hepatic injury: a potential complication of high-dose therapy. Cancer Treat Rep 67 (1983) 1023-1024
    • (1983) Cancer Treat Rep , vol.67 , pp. 1023-1024
    • Wolff, S.N.1    Johnson, D.H.2    Greco, F.A.3
  • 84
    • 0024570002 scopus 로고
    • Altered protein binding of etoposide in patients with cancer
    • Stewart C.F., Pieper J.A., Arbuck S.G., et al. Altered protein binding of etoposide in patients with cancer. Clin Pharmacol Ther 45 (1989) 49-55
    • (1989) Clin Pharmacol Ther , vol.45 , pp. 49-55
    • Stewart, C.F.1    Pieper, J.A.2    Arbuck, S.G.3
  • 85
    • 0022976121 scopus 로고
    • Etoposide pharmacokinetics in patients with normal and abnormal organ function
    • Arbuck S.G., Douglas H.O., Crom W.R., et al. Etoposide pharmacokinetics in patients with normal and abnormal organ function. J Clin Oncol 4 (1986) 1690-1695
    • (1986) J Clin Oncol , vol.4 , pp. 1690-1695
    • Arbuck, S.G.1    Douglas, H.O.2    Crom, W.R.3
  • 87
    • 15844424667 scopus 로고    scopus 로고
    • Phase I and pharmacologic studies of topotecan in patients with impaired hepatic function
    • O'Reilly S., Rowinsky E., Slichenmyer W., et al. Phase I and pharmacologic studies of topotecan in patients with impaired hepatic function. J Natl Cancer Inst 88 (1996) 817-824
    • (1996) J Natl Cancer Inst , vol.88 , pp. 817-824
    • O'Reilly, S.1    Rowinsky, E.2    Slichenmyer, W.3
  • 88
    • 0035044891 scopus 로고    scopus 로고
    • Hepatotoxicity of chemotherapy
    • King P.D., and Perry M.C. Hepatotoxicity of chemotherapy. Oncologist 6 (2001) 162-176
    • (2001) Oncologist , vol.6 , pp. 162-176
    • King, P.D.1    Perry, M.C.2
  • 90
    • 32244432650 scopus 로고    scopus 로고
    • A risk benefit assessment of irinotecan in solid tumors
    • Siu L.L., and Rowinsky E.K. A risk benefit assessment of irinotecan in solid tumors. Drug Saf 4 (1998) 783-789
    • (1998) Drug Saf , vol.4 , pp. 783-789
    • Siu, L.L.1    Rowinsky, E.K.2
  • 91
    • 0029044165 scopus 로고
    • Paclitaxel pharmacokinetics and pharmacodynamics
    • Kearns C., Gianni L., and Egorin M. Paclitaxel pharmacokinetics and pharmacodynamics. Semin Oncol 22 (1995) 16-23
    • (1995) Semin Oncol , vol.22 , pp. 16-23
    • Kearns, C.1    Gianni, L.2    Egorin, M.3
  • 92
    • 0028090220 scopus 로고
    • Clinical pharmacokinetics of paclitaxel
    • Sonnichsen D.S., and Relling M.V. Clinical pharmacokinetics of paclitaxel. Clin Pharmacokinet 27 (1994) 256-269
    • (1994) Clin Pharmacokinet , vol.27 , pp. 256-269
    • Sonnichsen, D.S.1    Relling, M.V.2
  • 93
    • 0029584558 scopus 로고
    • Variability in human cytochrome P450 paclitaxel metabolism
    • Sonnichsen D.S., Liu Q., Schuetz E.G., et al. Variability in human cytochrome P450 paclitaxel metabolism. J Pharmacol Exp Ther 275 (1995) 566-575
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 566-575
    • Sonnichsen, D.S.1    Liu, Q.2    Schuetz, E.G.3
  • 94
    • 16844373250 scopus 로고    scopus 로고
    • Altered pharmacokinetics of paclitaxel in experimental hepatic or renal failure
    • Jiko M., Yano I., Okuda M., et al. Altered pharmacokinetics of paclitaxel in experimental hepatic or renal failure. Pharm Res 22 2 (2005) 228-234
    • (2005) Pharm Res , vol.22 , Issue.2 , pp. 228-234
    • Jiko, M.1    Yano, I.2    Okuda, M.3
  • 95
    • 0038341814 scopus 로고    scopus 로고
    • Pharmacokinetics of paclitaxel in rabbits with carbon tetrachloride-induced hepatic failure
    • Choi J.S. Pharmacokinetics of paclitaxel in rabbits with carbon tetrachloride-induced hepatic failure. Arch Pharm Res 25 6 (2002) 973-977
    • (2002) Arch Pharm Res , vol.25 , Issue.6 , pp. 973-977
    • Choi, J.S.1
  • 96
    • 0031832839 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic trial of paclitaxel in patients with hepatic dysfunction: Cancer and Leukemia Group B 9264
    • Venook A.P., Egorin M.J., Rosner G.L., et al. Phase I and pharmacokinetic trial of paclitaxel in patients with hepatic dysfunction: Cancer and Leukemia Group B 9264. J Clin Oncol 16 (1998) 1811-1819
    • (1998) J Clin Oncol , vol.16 , pp. 1811-1819
    • Venook, A.P.1    Egorin, M.J.2    Rosner, G.L.3
  • 97
    • 0033783410 scopus 로고    scopus 로고
    • Paclitaxel as weekly second-line therapy in patients with advanced pancreatic carcinoma
    • Oettle H., Arnold D., Esser M., et al. Paclitaxel as weekly second-line therapy in patients with advanced pancreatic carcinoma. Anticancer Drugs 11 8 (2000) 635-638
    • (2000) Anticancer Drugs , vol.11 , Issue.8 , pp. 635-638
    • Oettle, H.1    Arnold, D.2    Esser, M.3
  • 98
    • 0010231133 scopus 로고
    • Pharmacology of paclitaxel and its metabolites in patients with altered liver function
    • Huizing M.T., Rosing H., and Vermoken J. Pharmacology of paclitaxel and its metabolites in patients with altered liver function. Eur J Cancer 31A 5 (1995) S192
    • (1995) Eur J Cancer , vol.31 A , Issue.5
    • Huizing, M.T.1    Rosing, H.2    Vermoken, J.3
  • 99
    • 0030799902 scopus 로고    scopus 로고
    • Hepatic metabolism of paclitaxel and its impact in patients with altered hepatic function
    • Panday V.R., Huizing M.T., Willense P.H., et al. Hepatic metabolism of paclitaxel and its impact in patients with altered hepatic function. Semin Oncol 24 11 (1997) 34-38
    • (1997) Semin Oncol , vol.24 , Issue.11 , pp. 34-38
    • Panday, V.R.1    Huizing, M.T.2    Willense, P.H.3
  • 100
    • 0027787751 scopus 로고
    • Pharmacokinetics and metabolism of docetaxel
    • Bruno R., and Sanderink G.J. Pharmacokinetics and metabolism of docetaxel. Cancer Surv 17 (1993) 305-313
    • (1993) Cancer Surv , vol.17 , pp. 305-313
    • Bruno, R.1    Sanderink, G.J.2
  • 101
    • 17444438626 scopus 로고    scopus 로고
    • Factors predicting for efficacy and safety of docetaxel in a compassionate-use cohort of 825 heavily pre-treated advanced breast cancer patients
    • Alexandre J., Bleuzen P., Bonneterre J., et al. Factors predicting for efficacy and safety of docetaxel in a compassionate-use cohort of 825 heavily pre-treated advanced breast cancer patients. J Clin Oncol 18 (2000) 562-573
    • (2000) J Clin Oncol , vol.18 , pp. 562-573
    • Alexandre, J.1    Bleuzen, P.2    Bonneterre, J.3
  • 102
    • 0031982748 scopus 로고    scopus 로고
    • Population pharmacokinetics/pharmacodynamics of docetaxel in phase II studies in patients with cancer
    • Bruno R., Hill D., Riva A., et al. Population pharmacokinetics/pharmacodynamics of docetaxel in phase II studies in patients with cancer. J Clin Oncol 16 (1998) 187-196
    • (1998) J Clin Oncol , vol.16 , pp. 187-196
    • Bruno, R.1    Hill, D.2    Riva, A.3
  • 103
    • 0027787742 scopus 로고
    • Pharmacokinetics and metabolism of vinca alkaloids
    • Rahmani R., and Zhou X.J. Pharmacokinetics and metabolism of vinca alkaloids. Cancer Surv 17 (1993) 269-281
    • (1993) Cancer Surv , vol.17 , pp. 269-281
    • Rahmani, R.1    Zhou, X.J.2
  • 104
    • 0021126742 scopus 로고
    • Hepatotoxicity following vincristine therapy
    • El Saghir N.S., and Hawkins K.A. Hepatotoxicity following vincristine therapy. Cancer 54 (1984) 2006-2008
    • (1984) Cancer , vol.54 , pp. 2006-2008
    • El Saghir, N.S.1    Hawkins, K.A.2
  • 106
    • 0019983525 scopus 로고
    • The pharmacokinetics of vincristine in man: reduced drug clearance associated with raised serum alkaline phosphatase and dose-limited elimination
    • Van Den Berg H., Desai Z.R., Wilson R., et al. The pharmacokinetics of vincristine in man: reduced drug clearance associated with raised serum alkaline phosphatase and dose-limited elimination. Cancer Chemother Pharmacol 8 (1982) 215-219
    • (1982) Cancer Chemother Pharmacol , vol.8 , pp. 215-219
    • Van Den Berg, H.1    Desai, Z.R.2    Wilson, R.3
  • 107
    • 2942571277 scopus 로고    scopus 로고
    • A phase II study of ET-743/trabectedin for patients with advanced gastrointestinal stromal tumors
    • Blay J.Y., Le Cesne A., Verweij J., et al. A phase II study of ET-743/trabectedin for patients with advanced gastrointestinal stromal tumors. Eur J Cancer 40 9 (2004) 1327-1331
    • (2004) Eur J Cancer , vol.40 , Issue.9 , pp. 1327-1331
    • Blay, J.Y.1    Le Cesne, A.2    Verweij, J.3
  • 108
    • 2342461682 scopus 로고    scopus 로고
    • Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy
    • Garcia-Carbonero R., Supko J.G., Manola J., et al. Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy. J Clin Oncol 22 8 (2004) 1480-1490
    • (2004) J Clin Oncol , vol.22 , Issue.8 , pp. 1480-1490
    • Garcia-Carbonero, R.1    Supko, J.G.2    Manola, J.3
  • 109
    • 14644423300 scopus 로고    scopus 로고
    • Hepatotoxicity and metabolism of trabectedin: a literature review
    • Beumer J.H., Schellens J.H.M., and Beijnen J.H. Hepatotoxicity and metabolism of trabectedin: a literature review. Pharmacol Res 51 (2005) 391-398
    • (2005) Pharmacol Res , vol.51 , pp. 391-398
    • Beumer, J.H.1    Schellens, J.H.M.2    Beijnen, J.H.3
  • 110
    • 0041330535 scopus 로고    scopus 로고
    • Yondelis (trabectedin, ET-743): the development of an anticancer agent of marine origin
    • Van Kesteren C., de Vooght M.M., Lopez-Lazaro L., et al. Yondelis (trabectedin, ET-743): the development of an anticancer agent of marine origin. Anticancer Drugs 14 7 (2003) 487-502
    • (2003) Anticancer Drugs , vol.14 , Issue.7 , pp. 487-502
    • Van Kesteren, C.1    de Vooght, M.M.2    Lopez-Lazaro, L.3
  • 111
    • 33745161449 scopus 로고    scopus 로고
    • Steroid premedication markedly reduces liver and bone marrow toxicity of trabectedin in advanced sarcoma
    • Grosso F., Dileo P., Sanfilippo R., et al. Steroid premedication markedly reduces liver and bone marrow toxicity of trabectedin in advanced sarcoma. Eur J Cancer 42 10 (2006) 1484-1490
    • (2006) Eur J Cancer , vol.42 , Issue.10 , pp. 1484-1490
    • Grosso, F.1    Dileo, P.2    Sanfilippo, R.3
  • 112
    • 0141731283 scopus 로고    scopus 로고
    • Complete protection by high-dose dexamethasone against the hepatotoxicity of the novel antitumor drug Yondelis (ET-743) in the rat
    • Donald S., Verschoyle R.D., Greaves P., et al. Complete protection by high-dose dexamethasone against the hepatotoxicity of the novel antitumor drug Yondelis (ET-743) in the rat. Cancer Res 63 18 (2003) 5902-5908
    • (2003) Cancer Res , vol.63 , Issue.18 , pp. 5902-5908
    • Donald, S.1    Verschoyle, R.D.2    Greaves, P.3
  • 113
    • 27644470779 scopus 로고    scopus 로고
    • Gemtuzumab ozogamicin. A review of its use in acute myeloid leukemia
    • Fenton C., and Perry C. Gemtuzumab ozogamicin. A review of its use in acute myeloid leukemia. Drugs 65 16 (2005) 2406-2427
    • (2005) Drugs , vol.65 , Issue.16 , pp. 2406-2427
    • Fenton, C.1    Perry, C.2
  • 114
    • 25144485908 scopus 로고    scopus 로고
    • Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33-positive acute myeloid leukemia in first recurrence
    • Larson R.A., Sievers E.L., Stadmauer E.A., et al. Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33-positive acute myeloid leukemia in first recurrence. Cancer 104 7 (2005) 1442-1452
    • (2005) Cancer , vol.104 , Issue.7 , pp. 1442-1452
    • Larson, R.A.1    Sievers, E.L.2    Stadmauer, E.A.3
  • 115
    • 0034900174 scopus 로고    scopus 로고
    • Bross PF, Beitz J, Chen G, et al. Approval summary: gemtuzumab ozogamicin in relapsed acute myeloid leukemia. Clin Cancer Res 1001;7:1490-6
  • 116
    • 0037217782 scopus 로고    scopus 로고
    • Alvarado Y, Tsimberidou A, Kantarjian H, et al. Pilot study of Mylotarg, idarubicin and cytarabine combination regimen in patients with primary resistant or relapsed acute myeloid leucemia. Cancer Chemother Pharmacol 220;51:87-90
  • 117
    • 34548127104 scopus 로고    scopus 로고
    • Spotlight on gemtuzumab ozogamicin in acute myeloid leukemia
    • Fenton C., and Perry C. Spotlight on gemtuzumab ozogamicin in acute myeloid leukemia. Biodrugs 20 2 (2006) 137-139
    • (2006) Biodrugs , vol.20 , Issue.2 , pp. 137-139
    • Fenton, C.1    Perry, C.2
  • 118
    • 1842633680 scopus 로고    scopus 로고
    • Gefitinib, a novel, orally administered agent for the treatment of cancer
    • Ransom M., and Wardell S. Gefitinib, a novel, orally administered agent for the treatment of cancer. J Clin Pharm Ther 29 2 (2004) 95-103
    • (2004) J Clin Pharm Ther , vol.29 , Issue.2 , pp. 95-103
    • Ransom, M.1    Wardell, S.2
  • 120
    • 33644845421 scopus 로고    scopus 로고
    • First-line single agent treatment with gefitinib in patients with advanced non-small-cell lung cancer: a phase II study
    • Niho S., Kubota K., Goto K., et al. First-line single agent treatment with gefitinib in patients with advanced non-small-cell lung cancer: a phase II study. J Clin Oncol 24 1 (2006) 64-69
    • (2006) J Clin Oncol , vol.24 , Issue.1 , pp. 64-69
    • Niho, S.1    Kubota, K.2    Goto, K.3
  • 121
    • 34247362425 scopus 로고    scopus 로고
    • Promising new treatment schedule for gefitinib responders after severe hepatotoxicity with daily administration
    • Seki N., Uematsu K., Shibakuki R., et al. Promising new treatment schedule for gefitinib responders after severe hepatotoxicity with daily administration. J Clin Oncol 19 1 (2006) 3213-3214
    • (2006) J Clin Oncol , vol.19 , Issue.1 , pp. 3213-3214
    • Seki, N.1    Uematsu, K.2    Shibakuki, R.3
  • 122
    • 33846545477 scopus 로고    scopus 로고
    • Acute drug induced hepatitis due to erlotinib
    • Ramanarayanan J., and Scarpace S.L. Acute drug induced hepatitis due to erlotinib. JOP 8 1 (2007) 39-43
    • (2007) JOP , vol.8 , Issue.1 , pp. 39-43
    • Ramanarayanan, J.1    Scarpace, S.L.2
  • 123
    • 20844455755 scopus 로고    scopus 로고
    • Severe hepatitis and complete molecular response caused by imatinib mesylate: possible association of its concentration with clinical outcomes
    • Kikuchi S., Muroi K., Takahashi S., et al. Severe hepatitis and complete molecular response caused by imatinib mesylate: possible association of its concentration with clinical outcomes. Leuk Lymphoma 45 (2004) 2349-2351
    • (2004) Leuk Lymphoma , vol.45 , pp. 2349-2351
    • Kikuchi, S.1    Muroi, K.2    Takahashi, S.3
  • 124
    • 85044556764 scopus 로고    scopus 로고
    • Imatinib mesylate induced hepatotoxicity in chronic myeloid leukemia demonstrated focal necrosis resembling acute viral hepatitis
    • Ohyashiki K., Kuriyama Y., Nakajima A., et al. Imatinib mesylate induced hepatotoxicity in chronic myeloid leukemia demonstrated focal necrosis resembling acute viral hepatitis. Leukemia 16 (2004) 2160-2161
    • (2004) Leukemia , vol.16 , pp. 2160-2161
    • Ohyashiki, K.1    Kuriyama, Y.2    Nakajima, A.3
  • 125
    • 10744220743 scopus 로고    scopus 로고
    • Imatinib mesylate capsules for treatment of adult patients with newly diagnosed Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase
    • Johnson J.R., Bross P., Cohen M., et al. Imatinib mesylate capsules for treatment of adult patients with newly diagnosed Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase. Clin Cancer Res 9 (2003) 1972-1979
    • (2003) Clin Cancer Res , vol.9 , pp. 1972-1979
    • Johnson, J.R.1    Bross, P.2    Cohen, M.3
  • 126
    • 0035810147 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the BCRABL tyrosine kinase in chronic myeloid leukemia
    • Druker B.J., Talpaz M., Resta D.J., et al. Efficacy and safety of a specific inhibitor of the BCRABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 344 (2001) 1031-1037
    • (2001) N Engl J Med , vol.344 , pp. 1031-1037
    • Druker, B.J.1    Talpaz, M.2    Resta, D.J.3
  • 127
    • 33845444046 scopus 로고    scopus 로고
    • Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
    • Druker B.J., Guilhot F., O'Brien S.G., et al. Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med 355 23 (2006) 2408-2417
    • (2006) N Engl J Med , vol.355 , Issue.23 , pp. 2408-2417
    • Druker, B.J.1    Guilhot, F.2    O'Brien, S.G.3
  • 128
    • 0036094117 scopus 로고    scopus 로고
    • Approval summary for imatinib mesylate capsules in the treatment of chronic myelogenous leukemia
    • Cohen M.H., Williams G., Johnson J.R., et al. Approval summary for imatinib mesylate capsules in the treatment of chronic myelogenous leukemia. Clin Cancer Res 8 (2002) 935-942
    • (2002) Clin Cancer Res , vol.8 , pp. 935-942
    • Cohen, M.H.1    Williams, G.2    Johnson, J.R.3
  • 129
    • 33644533526 scopus 로고    scopus 로고
    • Imatinib mesylate as a cause of acute liver failure
    • Cross T.J., Bagot C., Portmann B., et al. Imatinib mesylate as a cause of acute liver failure. Am J Hematol 81 3 (2006) 189-192
    • (2006) Am J Hematol , vol.81 , Issue.3 , pp. 189-192
    • Cross, T.J.1    Bagot, C.2    Portmann, B.3
  • 130
    • 0142214621 scopus 로고    scopus 로고
    • Fatal hepatic necrosis following imatinib mesylate therapy
    • Lin N.U., Sarantopoulos S., Stone J.R., et al. Fatal hepatic necrosis following imatinib mesylate therapy. Blood 102 (2003) 3455-3456
    • (2003) Blood , vol.102 , pp. 3455-3456
    • Lin, N.U.1    Sarantopoulos, S.2    Stone, J.R.3
  • 131
  • 132
    • 2942619994 scopus 로고    scopus 로고
    • Indications for imatinib mesylate therapy and clinical management
    • Guilhot F. Indications for imatinib mesylate therapy and clinical management. The Oncologist 9 (2004) 271-281
    • (2004) The Oncologist , vol.9 , pp. 271-281
    • Guilhot, F.1
  • 133
    • 33846839517 scopus 로고    scopus 로고
    • Imatinib mesylate (Gleevec) hepatotoxicity
    • Mindikoglu A.L., Regev A., Bejarano P.A., et al. Imatinib mesylate (Gleevec) hepatotoxicity. Dig Dis Sci 52 (2007) 598-601
    • (2007) Dig Dis Sci , vol.52 , pp. 598-601
    • Mindikoglu, A.L.1    Regev, A.2    Bejarano, P.A.3
  • 134
    • 33749847883 scopus 로고    scopus 로고
    • Imatinib mesylate-induced acute hepatitis with autoimmune features
    • Dhalluin-Venier V., Besson C., Dimet S., et al. Imatinib mesylate-induced acute hepatitis with autoimmune features. Eur J Gastroenterol Hepatol 18 11 (2006) 1235-1237
    • (2006) Eur J Gastroenterol Hepatol , vol.18 , Issue.11 , pp. 1235-1237
    • Dhalluin-Venier, V.1    Besson, C.2    Dimet, S.3
  • 135
    • 33644697678 scopus 로고    scopus 로고
    • Severe hepatic injury caused by imatinib mesylate administered for the treatment of chronic myeloid leukemia and the efficacy of prednisolone for its management
    • Ikuta K., Torimoto Y., Jimbo J., et al. Severe hepatic injury caused by imatinib mesylate administered for the treatment of chronic myeloid leukemia and the efficacy of prednisolone for its management. Int J Hematol 82 4 (2005) 343-346
    • (2005) Int J Hematol , vol.82 , Issue.4 , pp. 343-346
    • Ikuta, K.1    Torimoto, Y.2    Jimbo, J.3
  • 136
    • 33749348926 scopus 로고    scopus 로고
    • Corticosteroids can reverse severe imatinib-induced hepatotoxicity
    • Ferrero D., Pogliani E.M., Rege-Cambrin G., et al. Corticosteroids can reverse severe imatinib-induced hepatotoxicity. Haemotologica 91 (2006) 35-37
    • (2006) Haemotologica , vol.91 , pp. 35-37
    • Ferrero, D.1    Pogliani, E.M.2    Rege-Cambrin, G.3
  • 137
    • 33746408229 scopus 로고    scopus 로고
    • Comprehensive side-effect profile of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: long-term safety analysis of the ATAC trial
    • Buzdar A., Howell A.Z.Z., Cuzick J., et al. Comprehensive side-effect profile of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: long-term safety analysis of the ATAC trial. Lancet Oncol 7 (2006) 633-643
    • (2006) Lancet Oncol , vol.7 , pp. 633-643
    • Buzdar, A.1    Howell, A.Z.Z.2    Cuzick, J.3
  • 138
    • 33845903584 scopus 로고    scopus 로고
    • Severe acute hepatitis in a patient treated with anastrozole
    • de la Cruz L., Romero-Vasquez J., Jimenez-Saenz M., et al. Severe acute hepatitis in a patient treated with anastrozole. Lancet 369 (2007) 23-24
    • (2007) Lancet , vol.369 , pp. 23-24
    • de la Cruz, L.1    Romero-Vasquez, J.2    Jimenez-Saenz, M.3
  • 140
    • 34548125070 scopus 로고    scopus 로고
    • Anastrozole had a better risk-benefit profile than tamoxifen as adjuvant treatment for breast cancer in postmenopausal women
    • Hillner B.E. Anastrozole had a better risk-benefit profile than tamoxifen as adjuvant treatment for breast cancer in postmenopausal women. ACP J Club 146 1 (2007) 4
    • (2007) ACP J Club , vol.146 , Issue.1 , pp. 4
    • Hillner, B.E.1
  • 141
    • 19944408390 scopus 로고    scopus 로고
    • Preoperative gefitinib versus gefitinib and anastrozole in postmenopausal patients with oestrogen-receptor positive and epidermal-growth-factor-receptor-positive primary breast cancer: a double-blind placebo-controlled phase II randomised trial
    • Polychronis A., Sinnett H.D., Hadjiminas D., et al. Preoperative gefitinib versus gefitinib and anastrozole in postmenopausal patients with oestrogen-receptor positive and epidermal-growth-factor-receptor-positive primary breast cancer: a double-blind placebo-controlled phase II randomised trial. Lancet Oncol 6 (2005) 383-391
    • (2005) Lancet Oncol , vol.6 , pp. 383-391
    • Polychronis, A.1    Sinnett, H.D.2    Hadjiminas, D.3
  • 142
    • 34548120950 scopus 로고    scopus 로고
    • Liver toxicity after treatment with gefitinib and anastrozole: drug-drug interactions through cytochrome p450?
    • Carlini P., Papaldo P., Fabi A., et al. Liver toxicity after treatment with gefitinib and anastrozole: drug-drug interactions through cytochrome p450?. J Clin Oncol 24 35 (2006) e60-e61
    • (2006) J Clin Oncol , vol.24 , Issue.35
    • Carlini, P.1    Papaldo, P.2    Fabi, A.3
  • 143
    • 0033013140 scopus 로고    scopus 로고
    • Frequency of flutamide induced hepatotoxicity in patients with prostate carcinoma
    • Cetin M., Demirci D., Unal A., et al. Frequency of flutamide induced hepatotoxicity in patients with prostate carcinoma. Hum Exp Toxicol 18 (1999) 137-140
    • (1999) Hum Exp Toxicol , vol.18 , pp. 137-140
    • Cetin, M.1    Demirci, D.2    Unal, A.3
  • 144
    • 12144290215 scopus 로고    scopus 로고
    • Toxic hepatitis and liver failure under therapy with flutamide
    • Lubbert C., Wiese M., Haupt R., et al. Toxic hepatitis and liver failure under therapy with flutamide. Internist 45 3 (2004) 333-340
    • (2004) Internist , vol.45 , Issue.3 , pp. 333-340
    • Lubbert, C.1    Wiese, M.2    Haupt, R.3
  • 145
    • 0029887994 scopus 로고    scopus 로고
    • Flutamide-induced liver toxicity including fatal hepatic necrosis
    • Crownover R.L., Holland J., Chen A., et al. Flutamide-induced liver toxicity including fatal hepatic necrosis. Int J Radiat Oncol Biol Phys 34 4 (1996) 911-915
    • (1996) Int J Radiat Oncol Biol Phys , vol.34 , Issue.4 , pp. 911-915
    • Crownover, R.L.1    Holland, J.2    Chen, A.3
  • 146
    • 0032990046 scopus 로고    scopus 로고
    • Fatal hepatic failure following hepatitis caused by flutamide: a case report
    • Okaneya T., Murata Y., and Kinebuchi Y. Fatal hepatic failure following hepatitis caused by flutamide: a case report. Nippon Hinyokika Gakkai Zasshi 90 5 (1999) 590-593
    • (1999) Nippon Hinyokika Gakkai Zasshi , vol.90 , Issue.5 , pp. 590-593
    • Okaneya, T.1    Murata, Y.2    Kinebuchi, Y.3
  • 147
  • 148
    • 0034892086 scopus 로고    scopus 로고
    • Flutamide-induced hepatotoxicity: report of a case series
    • Garcia Cortes M., Andrade R.J., Lucena M.I., et al. Flutamide-induced hepatotoxicity: report of a case series. Rev Esp Enferm Dig 93 7 (2001) 423-432
    • (2001) Rev Esp Enferm Dig , vol.93 , Issue.7 , pp. 423-432
    • Garcia Cortes, M.1    Andrade, R.J.2    Lucena, M.I.3
  • 150
    • 0027322427 scopus 로고
    • Fatal and nonfatal hepatotoxicity associated with flutamide
    • Wysowski D.K., Freiman J.P., Tourtelot J.B., et al. Fatal and nonfatal hepatotoxicity associated with flutamide. Ann Intern Med 118 11 (1993) 860-864
    • (1993) Ann Intern Med , vol.118 , Issue.11 , pp. 860-864
    • Wysowski, D.K.1    Freiman, J.P.2    Tourtelot, J.B.3
  • 151
    • 0031000134 scopus 로고    scopus 로고
    • Fulminant liver failure with a fatal outcome due to flutamide
    • Fernandez Pena C.M., Morano L.E., Montes S.J., et al. Fulminant liver failure with a fatal outcome due to flutamide. Med Clin (Barc) 108 6 (1997) 237-238
    • (1997) Med Clin (Barc) , vol.108 , Issue.6 , pp. 237-238
    • Fernandez Pena, C.M.1    Morano, L.E.2    Montes, S.J.3
  • 152
    • 0029782303 scopus 로고    scopus 로고
    • A case of flutamide-induced acute cholestatic hepatitis
    • Lee H.W., Chung J.P., Lee K.S., et al. A case of flutamide-induced acute cholestatic hepatitis. Yonsei Med J 37 3 (1996) 225-229
    • (1996) Yonsei Med J , vol.37 , Issue.3 , pp. 225-229
    • Lee, H.W.1    Chung, J.P.2    Lee, K.S.3
  • 153
    • 0029656166 scopus 로고    scopus 로고
    • Flutamide and hepatotoxicity
    • Wysowski D.K., and Fourcroy J.L. Flutamide and hepatotoxicity. J Urol 155 (1996) 209-212
    • (1996) J Urol , vol.155 , pp. 209-212
    • Wysowski, D.K.1    Fourcroy, J.L.2
  • 154
    • 10744223518 scopus 로고    scopus 로고
    • Antiandrogen-associated hepatotoxicity in the management of advanced prostate cancer
    • Lin A.D., Chen K.K., Lin A.T., et al. Antiandrogen-associated hepatotoxicity in the management of advanced prostate cancer. J Chin Med Assoc 66 12 (2003) 735-740
    • (2003) J Chin Med Assoc , vol.66 , Issue.12 , pp. 735-740
    • Lin, A.D.1    Chen, K.K.2    Lin, A.T.3
  • 155
    • 33646071805 scopus 로고    scopus 로고
    • Spontaneous reporting of hepatotoxicity associated with antiandrogens: data from the Spanish pharmacovigilance system
    • Manso G., Thole Z., Salqueiro E., et al. Spontaneous reporting of hepatotoxicity associated with antiandrogens: data from the Spanish pharmacovigilance system. Pharmacoepidemiol Drug Saf 15 4 (2006) 253-259
    • (2006) Pharmacoepidemiol Drug Saf , vol.15 , Issue.4 , pp. 253-259
    • Manso, G.1    Thole, Z.2    Salqueiro, E.3
  • 156
    • 33749437211 scopus 로고    scopus 로고
    • Bioactivation and hepatotoxicity of nitroaromatic drugs
    • Boelsterli U.A., Ho H.K., Zhou S., et al. Bioactivation and hepatotoxicity of nitroaromatic drugs. Curr Drug Metab 7 7 (2006) 715-727
    • (2006) Curr Drug Metab , vol.7 , Issue.7 , pp. 715-727
    • Boelsterli, U.A.1    Ho, H.K.2    Zhou, S.3
  • 157
    • 33646550874 scopus 로고    scopus 로고
    • Long-term, low-dose flutamide does not cause hepatotoxicity in hyperandrogenic women
    • Legro R.S. Long-term, low-dose flutamide does not cause hepatotoxicity in hyperandrogenic women. Nat Clin Pract Endocrinol Metab 2 4 (2006) 188-189
    • (2006) Nat Clin Pract Endocrinol Metab , vol.2 , Issue.4 , pp. 188-189
    • Legro, R.S.1
  • 158
    • 21644478010 scopus 로고    scopus 로고
    • Absence of hepatotoxicity after long-term, low-dose flutamide in hyperandrogenic girls and young women
    • Ibanez L., Jaramillo A., Ferrer A., et al. Absence of hepatotoxicity after long-term, low-dose flutamide in hyperandrogenic girls and young women. Hum Reprod 20 7 (2005) 1833-1836
    • (2005) Hum Reprod , vol.20 , Issue.7 , pp. 1833-1836
    • Ibanez, L.1    Jaramillo, A.2    Ferrer, A.3
  • 159
    • 0036010624 scopus 로고    scopus 로고
    • Clinical utility of ursodeoxycholic acid in preventing flutamide-induced hepatopathy in patients with prostate cancer: a preliminary study
    • Kojima M., Kamoi K., Ukimura O., et al. Clinical utility of ursodeoxycholic acid in preventing flutamide-induced hepatopathy in patients with prostate cancer: a preliminary study. Int J Urol 9 1 (2002) 42-46
    • (2002) Int J Urol , vol.9 , Issue.1 , pp. 42-46
    • Kojima, M.1    Kamoi, K.2    Ukimura, O.3
  • 160
    • 0029807157 scopus 로고    scopus 로고
    • Flutamide-induced toxic hepatitis. Potential utility of ursodeoxycholic acid administration in toxic hepatitis
    • Cicognani C., Malavolti M., Morselli-Labate A.M., et al. Flutamide-induced toxic hepatitis. Potential utility of ursodeoxycholic acid administration in toxic hepatitis. Dig Dis Sci 41 11 (1996) 2219-2221
    • (1996) Dig Dis Sci , vol.41 , Issue.11 , pp. 2219-2221
    • Cicognani, C.1    Malavolti, M.2    Morselli-Labate, A.M.3
  • 161
    • 34548118452 scopus 로고    scopus 로고
    • Velcade (bortezomib) [package insert]. Cambridge (MA): Millenium Pharmaceuticals; 2003
  • 162
    • 17644379385 scopus 로고    scopus 로고
    • Pharmacology, pharmacokinetics, and practical applications of bortezomib
    • Schwartz R., and Davidson T. Pharmacology, pharmacokinetics, and practical applications of bortezomib. Oncology 18 14 (2004) 14-21
    • (2004) Oncology , vol.18 , Issue.14 , pp. 14-21
    • Schwartz, R.1    Davidson, T.2
  • 163
    • 33745802177 scopus 로고    scopus 로고
    • Perspective on the current use of bortezomib in multiple myeloma
    • San Miguel J., and Blade J. Perspective on the current use of bortezomib in multiple myeloma. Haematologica 91 7 (2006) 871-872
    • (2006) Haematologica , vol.91 , Issue.7 , pp. 871-872
    • San Miguel, J.1    Blade, J.2
  • 164
    • 14044264214 scopus 로고    scopus 로고
    • Bortezomib-induced severe hepatitis in multiple myeloma: a case report
    • Rosinol L., Montoto S., Cibeira M.T., et al. Bortezomib-induced severe hepatitis in multiple myeloma: a case report. Arch Intern Med 165 (2005) 464-465
    • (2005) Arch Intern Med , vol.165 , pp. 464-465
    • Rosinol, L.1    Montoto, S.2    Cibeira, M.T.3
  • 165
    • 0032748385 scopus 로고    scopus 로고
    • Antitumor activity of thalidomide in refractory multiple myeloma
    • Singhal S., Mehta J., Desikan R., et al. Antitumor activity of thalidomide in refractory multiple myeloma. N Engl J Med 341 (1999) 1565-1571
    • (1999) N Engl J Med , vol.341 , pp. 1565-1571
    • Singhal, S.1    Mehta, J.2    Desikan, R.3
  • 166
    • 0036464605 scopus 로고    scopus 로고
    • Efficacy and safety of thalidomide in patients with acute myeloid leukemia
    • Steins M.B., Padro T., Bieker R., et al. Efficacy and safety of thalidomide in patients with acute myeloid leukemia. Blood 99 (2002) 834-839
    • (2002) Blood , vol.99 , pp. 834-839
    • Steins, M.B.1    Padro, T.2    Bieker, R.3
  • 167
    • 5344258973 scopus 로고    scopus 로고
    • Adverse effects of thalidomide administration in patients with neoplastic diseases
    • Dimopoulos M., and Eleutherakis-Papaiakovou V. Adverse effects of thalidomide administration in patients with neoplastic diseases. Am J Med 117 7 (2004) 508-515
    • (2004) Am J Med , vol.117 , Issue.7 , pp. 508-515
    • Dimopoulos, M.1    Eleutherakis-Papaiakovou, V.2
  • 168
    • 2542635663 scopus 로고    scopus 로고
    • Common and rare side-effects of low-dose thalidomide in multiple myeloma: focus on the dose-minimizing peripheral neuropathy
    • Offidani M., Corvatta L., Marconi M., et al. Common and rare side-effects of low-dose thalidomide in multiple myeloma: focus on the dose-minimizing peripheral neuropathy. Eur J Haematol 72 6 (2004) 403-409
    • (2004) Eur J Haematol , vol.72 , Issue.6 , pp. 403-409
    • Offidani, M.1    Corvatta, L.2    Marconi, M.3
  • 169
    • 0035098477 scopus 로고    scopus 로고
    • Thalidomide-associated hepatitis: a case report
    • Fowler R., and Imrie K. Thalidomide-associated hepatitis: a case report. Am J Hematol 66 (2001) 300-302
    • (2001) Am J Hematol , vol.66 , pp. 300-302
    • Fowler, R.1    Imrie, K.2
  • 170
    • 0037350158 scopus 로고    scopus 로고
    • Severe hepatic toxicity due to thalidomide in relapsed multiple myeloma
    • Trojan A., Chasse E., Gay B., et al. Severe hepatic toxicity due to thalidomide in relapsed multiple myeloma. Ann Oncol 14 (2003) 501-502
    • (2003) Ann Oncol , vol.14 , pp. 501-502
    • Trojan, A.1    Chasse, E.2    Gay, B.3
  • 171
    • 0035342287 scopus 로고    scopus 로고
    • Advances in the treatment of metastatic colorectal cancer
    • Fishman A.D., and Wadler S. Advances in the treatment of metastatic colorectal cancer. Clin Colorectal Cancer 1 1 (2001) 20-35
    • (2001) Clin Colorectal Cancer , vol.1 , Issue.1 , pp. 20-35
    • Fishman, A.D.1    Wadler, S.2
  • 172
    • 0036270715 scopus 로고    scopus 로고
    • Raltitrexed in the treatment of elderly patients with advanced colorectal cancer an active and low toxicity regimen
    • Feliu J., Mel J.R., Camps C., et al. Raltitrexed in the treatment of elderly patients with advanced colorectal cancer an active and low toxicity regimen. Eur J Cancer 38 9 (2002) 1204-1211
    • (2002) Eur J Cancer , vol.38 , Issue.9 , pp. 1204-1211
    • Feliu, J.1    Mel, J.R.2    Camps, C.3
  • 173
    • 0036765690 scopus 로고    scopus 로고
    • Tolerability of raltitrexed ('Tomudex') in elderly patients with colorectal cancer
    • Romiti A., Tonini G., Santini G., et al. Tolerability of raltitrexed ('Tomudex') in elderly patients with colorectal cancer. Anticancer Res 22 5 (2002) 3071-3076
    • (2002) Anticancer Res , vol.22 , Issue.5 , pp. 3071-3076
    • Romiti, A.1    Tonini, G.2    Santini, G.3
  • 174
    • 0034663174 scopus 로고    scopus 로고
    • Fatal liver failure after the administration of raltitrexed for cancer chemotherapy: a report of two cases
    • Raderer M., Fiebiger W., Wrba F., et al. Fatal liver failure after the administration of raltitrexed for cancer chemotherapy: a report of two cases. Cancer 89 4 (2000) 890-892
    • (2000) Cancer , vol.89 , Issue.4 , pp. 890-892
    • Raderer, M.1    Fiebiger, W.2    Wrba, F.3
  • 175
    • 0035048940 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis with cirrhosis after raltitrexed administration
    • Flamenbaum M., Kemeny J.L., Garcia V., et al. Non-alcoholic steatohepatitis with cirrhosis after raltitrexed administration. Gastroenterol Clin Biol 25 2 (2001) 200-201
    • (2001) Gastroenterol Clin Biol , vol.25 , Issue.2 , pp. 200-201
    • Flamenbaum, M.1    Kemeny, J.L.2    Garcia, V.3
  • 176
    • 0041831125 scopus 로고    scopus 로고
    • Raltitrexed-induced hepatotoxicity: multivariate analysis of predictive factors
    • Massacesi C., Sanitin D., Rocchi M.B., et al. Raltitrexed-induced hepatotoxicity: multivariate analysis of predictive factors. Anti Cancer Drugs 14 7 (2003) 533-541
    • (2003) Anti Cancer Drugs , vol.14 , Issue.7 , pp. 533-541
    • Massacesi, C.1    Sanitin, D.2    Rocchi, M.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.