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Volumn 46, Issue 33, 2007, Pages 9453-9561

Elucidation of the interleukin-15 binding site on its alpha receptor by NMR

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA RECEPTORS; BINDING INTERACTION; INTERLEUKIN-15 BINDING SITE; STRUCTURAL HOMOLOGY;

EID: 34548078119     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi700652f     Document Type: Article
Times cited : (16)

References (45)
  • 1
    • 0028276796 scopus 로고
    • A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells
    • Burton, J. D., Bamford, R. N., Peters, C., Grant, A. J., Kurys, G., Goldman, C. K., Brennan, J., Roessler, E., and Waldmann, T. A. (1994) A lymphokine, provisionally designated interleukin T and produced by a human adult T-cell leukemia line, stimulates T-cell proliferation and the induction of lymphokine-activated killer cells, Proc. Natl. Acad. Sci. U.S.A. 91, 4935-4939.
    • (1994) Proc. Natl. Acad. Sci. U.S.A , vol.91 , pp. 4935-4939
    • Burton, J.D.1    Bamford, R.N.2    Peters, C.3    Grant, A.J.4    Kurys, G.5    Goldman, C.K.6    Brennan, J.7    Roessler, E.8    Waldmann, T.A.9
  • 2
    • 0028363377 scopus 로고
    • The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells
    • Bamford, R. N., Grant, A. J., Burton, J. D., Peters, C., Kurys, G., Goldman, C. K., Brennan, J., Roessler, E., and Waldmann, T. A. (1994) The interleukin (IL) 2 receptor beta chain is shared by IL-2 and a cytokine, provisionally designated IL-T, that stimulates T-cell proliferation and the induction of lymphokine-activated killer cells, Proc. Natl. Acad. Sci. U.S.A. 91, 4940-4944.
    • (1994) Proc. Natl. Acad. Sci. U.S.A , vol.91 , pp. 4940-4944
    • Bamford, R.N.1    Grant, A.J.2    Burton, J.D.3    Peters, C.4    Kurys, G.5    Goldman, C.K.6    Brennan, J.7    Roessler, E.8    Waldmann, T.A.9
  • 6
    • 13444257757 scopus 로고    scopus 로고
    • Interleukin-2, interleukin-15, and their roles in human natural killer cells
    • Becknell, B., and Caligiuri, M. A. (2005) Interleukin-2, interleukin-15, and their roles in human natural killer cells, Adv Immunol 86, 209-239.
    • (2005) Adv Immunol , vol.86 , pp. 209-239
    • Becknell, B.1    Caligiuri, M.A.2
  • 7
    • 0032076635 scopus 로고    scopus 로고
    • Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15
    • Zhang, X., Sun, S., Hwang, I., Tough, D. F., and Sprent, J. (1998) Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15, Immunity 8, 591-599.
    • (1998) Immunity , vol.8 , pp. 591-599
    • Zhang, X.1    Sun, S.2    Hwang, I.3    Tough, D.F.4    Sprent, J.5
  • 8
    • 0001585396 scopus 로고    scopus 로고
    • Control of homeostasis of CD8+ memory T cells by opposing cytokines
    • Ku, C. C., Murakami, M., Sakamoto, A., Kappler, J., and Marrack, P. (2000) Control of homeostasis of CD8+ memory T cells by opposing cytokines, Science 288, 675-678.
    • (2000) Science , vol.288 , pp. 675-678
    • Ku, C.C.1    Murakami, M.2    Sakamoto, A.3    Kappler, J.4    Marrack, P.5
  • 10
    • 0036960253 scopus 로고    scopus 로고
    • IL-15 is a growth factor and an activator of CD8 memory T cells
    • Weng, N. P., Liu, K., Catalfamo, M., Li, Y., and Henkart, P. A. (2002) IL-15 is a growth factor and an activator of CD8 memory T cells, Ann. N.Y. Acad. Sci. 975, 46-56.
    • (2002) Ann. N.Y. Acad. Sci , vol.975 , pp. 46-56
    • Weng, N.P.1    Liu, K.2    Catalfamo, M.3    Li, Y.4    Henkart, P.A.5
  • 11
    • 0037124341 scopus 로고    scopus 로고
    • Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells
    • Becker, T. C., Wherry, E. J., Boone, D., Murali-Krishna, K., Antia, R., Ma, A., and Ahmed, R. (2002) Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells, J. Exp. Med. 195, 1541-1548.
    • (2002) J. Exp. Med , vol.195 , pp. 1541-1548
    • Becker, T.C.1    Wherry, E.J.2    Boone, D.3    Murali-Krishna, K.4    Antia, R.5    Ma, A.6    Ahmed, R.7
  • 12
    • 0036625927 scopus 로고    scopus 로고
    • Critical role for IL-15 in innate immunity
    • Ohteki, T. (2002) Critical role for IL-15 in innate immunity, Curr. Mol. Med. 2, 371-380.
    • (2002) Curr. Mol. Med , vol.2 , pp. 371-380
    • Ohteki, T.1
  • 15
    • 0029099146 scopus 로고
    • Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor
    • Giri, J. G., Kumaki, S., Ahdieh, M., Friend, D. J., Loomis, A., Shanebeck, K., DuBose, R., Cosman, D., Park, L. S., and Anderson, D. M. (1995) Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor, EMBO J. 14, 3654-3663.
    • (1995) EMBO J , vol.14 , pp. 3654-3663
    • Giri, J.G.1    Kumaki, S.2    Ahdieh, M.3    Friend, D.J.4    Loomis, A.5    Shanebeck, K.6    DuBose, R.7    Cosman, D.8    Park, L.S.9    Anderson, D.M.10
  • 16
    • 33745812074 scopus 로고    scopus 로고
    • IL-15/IL-15 receptor biology: A guided tour through an expanding universe
    • Budagian, V., Bulanova, E., Paus, R., and Bulfone-Paus, S. (2006) IL-15/IL-15 receptor biology: A guided tour through an expanding universe, Cytokine Growth Factor Rev. 17, 259-280.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 259-280
    • Budagian, V.1    Bulanova, E.2    Paus, R.3    Bulfone-Paus, S.4
  • 17
    • 0025894780 scopus 로고
    • Three-dimensional structure of a complement control protein module in solution
    • Norman, D. G., Barlow, P. N., Baron, M., Day, A. J., Sim, R. B., and Campbell, I. D. (1991) Three-dimensional structure of a complement control protein module in solution, J. Mol. Biol. 219, 717-725.
    • (1991) J. Mol. Biol , vol.219 , pp. 717-725
    • Norman, D.G.1    Barlow, P.N.2    Baron, M.3    Day, A.J.4    Sim, R.B.5    Campbell, I.D.6
  • 18
    • 27944505913 scopus 로고    scopus 로고
    • Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors
    • Wang, X., Rickert, M., and Garcia, K. C. (2005) Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors, Science 310, 1159-1163.
    • (2005) Science , vol.310 , pp. 1159-1163
    • Wang, X.1    Rickert, M.2    Garcia, K.C.3
  • 19
    • 0035399559 scopus 로고    scopus 로고
    • The Sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo
    • Wei, X., Orchardson, M., Gracie, J. A., Leung, B. P., Gao, B., Guan, H., Niedbala, W., Paterson, G. K., McInnes, I. B., and Liew, F. Y. (2001) The Sushi domain of soluble IL-15 receptor alpha is essential for binding IL-15 and inhibiting inflammatory and allogenic responses in vitro and in vivo, J. Immunol. 167, 277-282.
    • (2001) J. Immunol , vol.167 , pp. 277-282
    • Wei, X.1    Orchardson, M.2    Gracie, J.A.3    Leung, B.P.4    Gao, B.5    Guan, H.6    Niedbala, W.7    Paterson, G.K.8    McInnes, I.B.9    Liew, F.Y.10
  • 20
    • 33644975335 scopus 로고    scopus 로고
    • Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins
    • Mortier, E., Quemener, A., Vusio, P., Lorenzen, I., Boublik, Y., Grotzinger, J., Plet, A., and Jacques, Y. (2006) Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins, J. Biol. Chem. 281, 1612-1619.
    • (2006) J. Biol. Chem , vol.281 , pp. 1612-1619
    • Mortier, E.1    Quemener, A.2    Vusio, P.3    Lorenzen, I.4    Boublik, Y.5    Grotzinger, J.6    Plet, A.7    Jacques, Y.8
  • 21
    • 3042538263 scopus 로고    scopus 로고
    • Compensatory energetic mechanisms mediating the assembly of signaling complexes between interleukin-2 and its alpha, beta, and gamma(c) receptors
    • Rickert, M., Boulanger, M. J., Goriatcheva, N., and Garcia, K. C. (2004) Compensatory energetic mechanisms mediating the assembly of signaling complexes between interleukin-2 and its alpha, beta, and gamma(c) receptors, J. Mol. Biol. 339, 1115-1128.
    • (2004) J. Mol. Biol , vol.339 , pp. 1115-1128
    • Rickert, M.1    Boulanger, M.J.2    Goriatcheva, N.3    Garcia, K.C.4
  • 22
    • 0036826914 scopus 로고    scopus 로고
    • IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells
    • Dubois, S., Mariner, J., Waldmann, T. A., and Tagaya, Y. (2002) IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells, Immunity 17, 537-547.
    • (2002) Immunity , vol.17 , pp. 537-547
    • Dubois, S.1    Mariner, J.2    Waldmann, T.A.3    Tagaya, Y.4
  • 23
    • 1642581680 scopus 로고    scopus 로고
    • Transregulation of memory CD8 T-cell proliferation by IL-15Ralpha+ bone marrow-derived cells
    • Schluns, K. S., Klonowski, K. D., and Lefrancois, L. (2004) Transregulation of memory CD8 T-cell proliferation by IL-15Ralpha+ bone marrow-derived cells, Blood 103, 988-994.
    • (2004) Blood , vol.103 , pp. 988-994
    • Schluns, K.S.1    Klonowski, K.D.2    Lefrancois, L.3
  • 24
    • 5444239242 scopus 로고    scopus 로고
    • Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis
    • Burkett, P. R., Koka, R., Chien, M., Chai, S., Boone, D. L., and Ma, A. (2004) Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis, J. Exp. Med. 200, 825-834.
    • (2004) J. Exp. Med , vol.200 , pp. 825-834
    • Burkett, P.R.1    Koka, R.2    Chien, M.3    Chai, S.4    Boone, D.L.5    Ma, A.6
  • 25
    • 9144241114 scopus 로고    scopus 로고
    • Cutting edge: Transpresentation of IL-15 by bone marrow-derived cells necessitates expression of IL-15 and IL-15R alpha by the same cells
    • Sandau, M. M., Schluns, K. S., Lefrancois, L., and Jameson, S. C. (2004) Cutting edge: transpresentation of IL-15 by bone marrow-derived cells necessitates expression of IL-15 and IL-15R alpha by the same cells, J. Immunol. 173, 6537-6541.
    • (2004) J. Immunol , vol.173 , pp. 6537-6541
    • Sandau, M.M.1    Schluns, K.S.2    Lefrancois, L.3    Jameson, S.C.4
  • 26
    • 85177155706 scopus 로고    scopus 로고
    • Johnston, J. A., Bacon, C. M., Finbloom, D. S., Rees, R. C., Kaplan, D., Shibuya, K., Ortaldo, J. R., Gupta, S., Chen, Y. Q., Giri, J. D., et al. (1995) Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15, Proc. Natl. Acad. Sci. U.S.A. 92, 8705-8709.
    • Johnston, J. A., Bacon, C. M., Finbloom, D. S., Rees, R. C., Kaplan, D., Shibuya, K., Ortaldo, J. R., Gupta, S., Chen, Y. Q., Giri, J. D., et al. (1995) Tyrosine phosphorylation and activation of STAT5, STAT3, and Janus kinases by interleukins 2 and 15, Proc. Natl. Acad. Sci. U.S.A. 92, 8705-8709.
  • 27
    • 33646580769 scopus 로고    scopus 로고
    • The structure of the interleukin-15 alpha receptor and its implications for ligand binding
    • Lorenzen, I., Dingley, A. J., Jacques, Y., and Grotzinger, J. (2006) The structure of the interleukin-15 alpha receptor and its implications for ligand binding, J. Biol. Chem. 281, 6642-6647.
    • (2006) J. Biol. Chem , vol.281 , pp. 6642-6647
    • Lorenzen, I.1    Dingley, A.J.2    Jacques, Y.3    Grotzinger, J.4
  • 28
    • 12444298109 scopus 로고    scopus 로고
    • Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: Insights into MHC bias and antigen specificity
    • Maynard, J., Petersson, K., Wilson, D. H., Adams, E. J., Blondelle, S. E., Boulanger, M. J., Wilson, D. B., and Garcia, K. C. (2005) Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity, Immunity 22, 81-92.
    • (2005) Immunity , vol.22 , pp. 81-92
    • Maynard, J.1    Petersson, K.2    Wilson, D.H.3    Adams, E.J.4    Blondelle, S.E.5    Boulanger, M.J.6    Wilson, D.B.7    Garcia, K.C.8
  • 29
    • 0033536626 scopus 로고    scopus 로고
    • Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency
    • Shusta, E. V., Kieke, M. C., Parke, E., Kranz, D. M., and Wittrup, K. D. (1999) Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency, J. Mol. Biol. 292, 949-956.
    • (1999) J. Mol. Biol , vol.292 , pp. 949-956
    • Shusta, E.V.1    Kieke, M.C.2    Parke, E.3    Kranz, D.M.4    Wittrup, K.D.5
  • 30
    • 0028219869 scopus 로고
    • Protein disulfide isomerase overexpression increases secretion of foreign proteins in Saccharomyces cerevisiae
    • Robinson, A. S., Hines, V., and Wittrup, K. D. (1994) Protein disulfide isomerase overexpression increases secretion of foreign proteins in Saccharomyces cerevisiae, Bio/Technology 12, 381-384.
    • (1994) Bio/Technology , vol.12 , pp. 381-384
    • Robinson, A.S.1    Hines, V.2    Wittrup, K.D.3
  • 31
    • 0037124328 scopus 로고    scopus 로고
    • Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells
    • Kieper, W. C., Tan, J. T., Bondi-Boyd, B., Gapin, L., Sprent, J., Ceredig, R., and Surh, C. D. (2002) Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cells, J. Exp. Med. 195, 1533-1539.
    • (2002) J. Exp. Med , vol.195 , pp. 1533-1539
    • Kieper, W.C.1    Tan, J.T.2    Bondi-Boyd, B.3    Gapin, L.4    Sprent, J.5    Ceredig, R.6    Surh, C.D.7
  • 32
    • 0037124366 scopus 로고    scopus 로고
    • Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells
    • Tan, J. T., Ernst, B., Kieper, W. C., LeRoy, E., Sprent, J., and Surh, C. D. (2002) Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells, J. Exp. Med. 195, 1523-1532.
    • (2002) J. Exp. Med , vol.195 , pp. 1523-1532
    • Tan, J.T.1    Ernst, B.2    Kieper, W.C.3    LeRoy, E.4    Sprent, J.5    Surh, C.D.6
  • 33
    • 0029400480 scopus 로고
    • NMRPipe: A multidimensional spectral processing system based on UNIX pipes
    • Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J., and Bax, A. (1995) NMRPipe: a multidimensional spectral processing system based on UNIX pipes, J. Biomol. NMR 6, 277-293.
    • (1995) J. Biomol. NMR , vol.6 , pp. 277-293
    • Delaglio, F.1    Grzesiek, S.2    Vuister, G.W.3    Zhu, G.4    Pfeifer, J.5    Bax, A.6
  • 34
    • 0004040543 scopus 로고    scopus 로고
    • University of California, San Francisco
    • Goddard, T. D., and Kneller, D. G. (1999) SPARKY 3, University of California, San Francisco.
    • (1999) SPARKY 3
    • Goddard, T.D.1    Kneller, D.G.2
  • 36
    • 0027136282 scopus 로고
    • Comparative protein modelling by satisfaction of spatial restraints
    • Sali, A., and Blundell, T. L. (1993) Comparative protein modelling by satisfaction of spatial restraints, J. Mol. Biol. 234, 779-815.
    • (1993) J. Mol. Biol , vol.234 , pp. 779-815
    • Sali, A.1    Blundell, T.L.2
  • 37
    • 20344387872 scopus 로고    scopus 로고
    • The structure of interleukin-2 complexed with its alpha receptor
    • Rickert, M., Wang, X., Boulanger, M. J., Goriatcheva, N., and Garcia, K. C. (2005) The structure of interleukin-2 complexed with its alpha receptor, Science 308, 1477-1480.
    • (2005) Science , vol.308 , pp. 1477-1480
    • Rickert, M.1    Wang, X.2    Boulanger, M.J.3    Goriatcheva, N.4    Garcia, K.C.5
  • 38
    • 13444307044 scopus 로고    scopus 로고
    • Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions
    • Krissinel, E., and Henrick, K. (2004) Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions, Acta Crystallogr., Sect. D: Biol. Crystallogr. 60, 2256-2268.
    • (2004) Acta Crystallogr., Sect. D: Biol. Crystallogr , vol.60 , pp. 2256-2268
    • Krissinel, E.1    Henrick, K.2
  • 40
    • 34548097866 scopus 로고    scopus 로고
    • DeLano Scientific, Palo Alto, CA, USA
    • DeLano, W. L. The PyMOL Molecular Graphics System (2002) DeLano Scientific, Palo Alto, CA, USA. http://www.pymol.org.
    • (2002)
    • DeLano, W.L.1
  • 43
    • 33750335080 scopus 로고    scopus 로고
    • Combined IL-15/IL-15Ralpha immunotherapy maximizes IL-15 activity in vivo
    • Stoklasek, T. A., Schluns, K. S., and Lefrancois, L. (2006) Combined IL-15/IL-15Ralpha immunotherapy maximizes IL-15 activity in vivo, J. Immunol. 177, 6072-6080.
    • (2006) J. Immunol , vol.177 , pp. 6072-6080
    • Stoklasek, T.A.1    Schluns, K.S.2    Lefrancois, L.3
  • 44
    • 0035896394 scopus 로고    scopus 로고
    • Structure of an extracellular gp130 cytokine receptor signaling complex
    • Chow, D., He, X., Snow, A. L., Rose-John, S., and Garcia, K. C. (2001) Structure of an extracellular gp130 cytokine receptor signaling complex, Science 291, 2150-2125.
    • (2001) Science , vol.291 , pp. 2150-2125
    • Chow, D.1    He, X.2    Snow, A.L.3    Rose-John, S.4    Garcia, K.C.5
  • 45
    • 0030008255 scopus 로고    scopus 로고
    • Interleukin (IL) 15/IL-T production by the adult T-cell leukemia cell line HuT-102 is associated with a human T-cell lymphotrophic virus type I region /IL-15 fusion message that lacks many upstream AUGs that normally attenuates IL-15 mRNA translation
    • Bamford, R. N., Battiata, A. P., Burton, J. D., Sharma, H., and Waldmann, T. A. (1996) Interleukin (IL) 15/IL-T production by the adult T-cell leukemia cell line HuT-102 is associated with a human T-cell lymphotrophic virus type I region /IL-15 fusion message that lacks many upstream AUGs that normally attenuates IL-15 mRNA translation. Proc. Natl. Acad. Sci. U.S.A. 93, 2897-2902.
    • (1996) Proc. Natl. Acad. Sci. U.S.A , vol.93 , pp. 2897-2902
    • Bamford, R.N.1    Battiata, A.P.2    Burton, J.D.3    Sharma, H.4    Waldmann, T.A.5


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