Kinetic studies of 25-hydroxy-19-nor-vitamin D3 and 1α,25-dihydroxy-19-nor-vitamin D3 hydroxylation by CYP27B1 and CYP24A1

Drug Metabolism and Disposition

Volumn 35, Issue 9, 2007, Pages 1482-1488

  Urushino, Naoko ^a   Nakabayashi, Sachie ^b   Arai, Midori A ^c   Kittaka, Atsushi ^c   Chen, Tai C ^d   Yamamoto, Keiko ^e,h   Hayashi, Keiko ^b   Kato, Shigeaki ^f   Ohta, Miho ^g   Kamakura, Masaki ^a   Ikushiro, Shinichi ^a   Sakaki, Toshiyuki ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b TOYAMA PREFECTURAL UNIVERSITY   (Japan)

^c TEIKYO UNIVERSITY   (Japan)

^d BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e Tokyo Medical and Dental University ^*  (Japan)

^f UNIVERSITY OF TOKYO   (Japan)

^g Soai University   (Japan)

^h SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1ALPHA,25 DIHYDROXY 19 NORVITAMIN D 3; 25 HYDROXY 19 NORVITAMIN D 3; CALCIFEDIOL; COLECALCIFEROL DERIVATIVE; CYTOCHROME P450; CYTOCHROME P450 24A1; CYTOCHROME P450 27B1; DRUG METABOLITE; UNCLASSIFIED DRUG;

ARTICLE; CELL FREE SYSTEM; CELL MIGRATION; CELL STRAIN; CONTROLLED STUDY; DRUG DEGRADATION; DRUG DETERMINATION; DRUG HYDROXYLATION; DRUG METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO SELECTION; KINETICS; MALE; PRIORITY JOURNAL; PROSTATE;

25-HYDROXYVITAMIN D3 1-ALPHA-HYDROXYLASE; ANIMALS; CALCITRIOL; CARBON MONOXIDE; CATTLE; CELL LINE; CELL PROLIFERATION; CHOLECALCIFEROL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; ESCHERICHIA COLI; HUMANS; HYDROXYLATION; KINETICS; MALE; MODELS, MOLECULAR; PLASMIDS; PROSTATE; THYMUS GLAND;

HUMAN PAPILLOMAVIRUS;

EID: 34548077902     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.107.015602     Document Type: Article

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