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Volumn 6, Issue 4, 2007, Pages 579-590

Vaccination against periodontitis: The saga continues

Author keywords

Immunization; Periodontal disease; Prevention; Vaccination

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL POLYSACCHARIDE; BACTERIAL VACCINE; BACTERIAL VECTOR; CAPSULAR POLYSACCHARIDE; CELL ENVELOPE ANTIGEN; CELL WALL ANTIGEN; CHOLERA TOXIN; CYSTEINE PROTEINASE; DRUG CARRIER; FIMBRIA PROTEIN; GINGIPAIN R; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 61BG13; MONOCLONAL ANTIBODY HAB OMP1; MONOCLONAL ANTIBODY HEMAGGLUTININ DOMAIN; MYCOBACTERIUM VACCAE VACCINE; PG32 ANTIGEN; PG33 ANTIGEN; PLANTIBODY; PORPHYPAIN 2; PORPHYROMONAS GINGIVALIS VACCINE; RABBIT ANTISERUM; UNCLASSIFIED DRUG;

EID: 34548039450     PISSN: 14760584     EISSN: 17448395     Source Type: Journal    
DOI: 10.1586/14760584.6.4.579     Document Type: Review
Times cited : (15)

References (89)
  • 1
    • 34548041924 scopus 로고    scopus 로고
    • Playfair J. Vaccination. In: Immunology. Roitt I, Brostoff J, Male D (Eds). Mosby, London, UK, 19.1-19.10 (1998).
    • Playfair J. Vaccination. In: Immunology. Roitt I, Brostoff J, Male D (Eds). Mosby, London, UK, 19.1-19.10 (1998).
  • 2
    • 0017103383 scopus 로고
    • Chemotherapy of dental plaque infections
    • Loesche WJ. Chemotherapy of dental plaque infections. Oral Sci. Rev. 9, 65-107 (1976).
    • (1976) Oral Sci. Rev , vol.9 , pp. 65-107
    • Loesche, W.J.1
  • 3
    • 0018564947 scopus 로고
    • Clinical and microbiological agents of chemotherapeutic gents used according to specific plaque hypothesis
    • Loesche WJ. Clinical and microbiological agents of chemotherapeutic gents used according to specific plaque hypothesis. J. Dent. Res. 58(12), 2404-2412 (1979).
    • (1979) J. Dent. Res , vol.58 , Issue.12 , pp. 2404-2412
    • Loesche, W.J.1
  • 4
    • 0022814811 scopus 로고
    • The non-specific theory in microbial etiology of inflammatory periodontal disease
    • Theilade E. The non-specific theory in microbial etiology of inflammatory periodontal disease. J. Clin. Periodontol. 13(10), 905-911 (1986).
    • (1986) J. Clin. Periodontol , vol.13 , Issue.10 , pp. 905-911
    • Theilade, E.1
  • 5
    • 33748995374 scopus 로고    scopus 로고
    • Nãrskov-Lauritsen M, Kilian M. Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. nov., comb. nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter aphrophilus to include V factor-dependent and V factor-independent isolates. Int. J. Syst. Evol. Microbiol. 56(9) 2135-2146 (2006).
    • Nãrskov-Lauritsen M, Kilian M. Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. nov., comb. nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter segnis comb. nov., and emended description of Aggregatibacter aphrophilus to include V factor-dependent and V factor-independent isolates. Int. J. Syst. Evol. Microbiol. 56(9) 2135-2146 (2006).
  • 6
    • 0032086731 scopus 로고    scopus 로고
    • Immunization with Porphyromonas gingivalis cysteine protease: Effects on experimental gingivitis and ligature induced periodontitis in Macaca fascicularis
    • Moritz AJ, Cappelli D, Lantz MS, Holt SC, Ebersole JL. Immunization with Porphyromonas gingivalis cysteine protease: effects on experimental gingivitis and ligature induced periodontitis in Macaca fascicularis. J. Periodontol. 69(6), 686-697 (1998).
    • (1998) J. Periodontol , vol.69 , Issue.6 , pp. 686-697
    • Moritz, A.J.1    Cappelli, D.2    Lantz, M.S.3    Holt, S.C.4    Ebersole, J.L.5
  • 8
    • 10944252426 scopus 로고    scopus 로고
    • Systemic antibiotics in periodontics
    • Slots J. Systemic antibiotics in periodontics. J. Periodontol. 75(11), 1553-1565 (2004).
    • (2004) J. Periodontol , vol.75 , Issue.11 , pp. 1553-1565
    • Slots, J.1
  • 9
    • 0030260753 scopus 로고    scopus 로고
    • Detection of human viruses in periodontal pockets using polymerase chain reaction
    • Parra B, Slots J. Detection of human viruses in periodontal pockets using polymerase chain reaction. Oral Microbiol. Immunol. 11(5), 289-293 (1996).
    • (1996) Oral Microbiol. Immunol , vol.11 , Issue.5 , pp. 289-293
    • Parra, B.1    Slots, J.2
  • 10
    • 0033125193 scopus 로고    scopus 로고
    • Relationship between herpesviruses and adult periodontitis and periodontopathic bacteria
    • Contreras A, Umeda M, Chen C, Bakker I, Morrison LJ, Slots J. Relationship between herpesviruses and adult periodontitis and periodontopathic bacteria. J. Periodontol. 70(5), 478-484 (1999).
    • (1999) J. Periodontol , vol.70 , Issue.5 , pp. 478-484
    • Contreras, A.1    Umeda, M.2    Chen, C.3    Bakker, I.4    Morrison, L.J.5    Slots, J.6
  • 11
    • 1442332861 scopus 로고    scopus 로고
    • Real-time PCR quantification of cytomegalovirus in aggressive periodontitis lesions using TaqMan technology
    • Kubar A, Saygun I, Yapar M, Ozdemir A, Slots J. Real-time PCR quantification of cytomegalovirus in aggressive periodontitis lesions using TaqMan technology. J. Periodontal Res. 39(2), 81-86 (2004).
    • (2004) J. Periodontal Res , vol.39 , Issue.2 , pp. 81-86
    • Kubar, A.1    Saygun, I.2    Yapar, M.3    Ozdemir, A.4    Slots, J.5
  • 12
    • 10944254868 scopus 로고    scopus 로고
    • Association between human herpesviruses and the severity of periodontitis
    • Ling LJ, Ho CC, Wu CY, Chen YT, Hung SL. Association between human herpesviruses and the severity of periodontitis. J. Periodontol. 75(11), 1479-1485 (2004).
    • (2004) J. Periodontol , vol.75 , Issue.11 , pp. 1479-1485
    • Ling, L.J.1    Ho, C.C.2    Wu, C.Y.3    Chen, Y.T.4    Hung, S.L.5
  • 13
    • 0036802797 scopus 로고    scopus 로고
    • Isolation of the provisionally named Desulfovibrio fairfieldensis from human periodontal pockets
    • Loubinoux J, Bisson-Boutelliez C, Miller N, Le Faou AE. Isolation of the provisionally named Desulfovibrio fairfieldensis from human periodontal pockets. Oral Microbiol. Immunol. 17(5), 321-323 (2002).
    • (2002) Oral Microbiol. Immunol , vol.17 , Issue.5 , pp. 321-323
    • Loubinoux, J.1    Bisson-Boutelliez, C.2    Miller, N.3    Le Faou, A.E.4
  • 15
    • 0023884997 scopus 로고
    • The predominant cultivable microbiota of active and inactive lesions of destructive periodontal disease
    • Dzink JL, Socransky SS, Haffajee AD. The predominant cultivable microbiota of active and inactive lesions of destructive periodontal disease. J. Clin. Periodontol. 15(5), 316-323 (1988).
    • (1988) J. Clin. Periodontol , vol.15 , Issue.5 , pp. 316-323
    • Dzink, J.L.1    Socransky, S.S.2    Haffajee, A.D.3
  • 16
    • 0027157758 scopus 로고
    • Pathogenicity and virulence of black-pigmented Gram-negative anaerobes
    • Sundqvist G. Pathogenicity and virulence of black-pigmented Gram-negative anaerobes. FEMS Immunol. Med. Microbiol. 6(2-3), 125-137 (1993).
    • (1993) FEMS Immunol. Med. Microbiol , vol.6 , Issue.2-3 , pp. 125-137
    • Sundqvist, G.1
  • 17
    • 0028031966 scopus 로고
    • Immunization against Porphyromonas gingivalis inhibits progression of experimental periodontitis in nonhuman primates
    • Persson GR, Engel D, Whitney C, Darveau R, Weinberg A, Brunsvold M. Immunization against Porphyromonas gingivalis inhibits progression of experimental periodontitis in nonhuman primates. Infect. Immun. 62(3), 1026-1031 (1994).
    • (1994) Infect. Immun , vol.62 , Issue.3 , pp. 1026-1031
    • Persson, G.R.1    Engel, D.2    Whitney, C.3    Darveau, R.4    Weinberg, A.5    Brunsvold, M.6
  • 18
    • 0033120801 scopus 로고    scopus 로고
    • Function of anti-Porphyromonas gingivalis immunoglobulin classes in immunized Macaca fascicularis
    • Houston LS, Lukehart SA, Persson GR, Page RC. Function of anti-Porphyromonas gingivalis immunoglobulin classes in immunized Macaca fascicularis. Oral Microbiol. Immunol. 14(2), 86-91 (1999).
    • (1999) Oral Microbiol. Immunol , vol.14 , Issue.2 , pp. 86-91
    • Houston, L.S.1    Lukehart, S.A.2    Persson, G.R.3    Page, R.C.4
  • 19
    • 0034175393 scopus 로고    scopus 로고
    • Vaccination and periodontitis: Myth or reality
    • Page RC. Vaccination and periodontitis: myth or reality. J. Int. Acad. Periodontol. 2(2), 31-43 (2000).
    • (2000) J. Int. Acad. Periodontol , vol.2 , Issue.2 , pp. 31-43
    • Page, R.C.1
  • 20
    • 1842588018 scopus 로고    scopus 로고
    • Porphyromonas gingivalis specific immunoglobulin G prevents Porphyromonas gingivalis elicited oral bone loss in a murine model
    • Gibson FC, Gonzalez DA, Wong J, Genco CA. Porphyromonas gingivalis specific immunoglobulin G prevents Porphyromonas gingivalis elicited oral bone loss in a murine model. Infect. Immun. 72(4), 2408-2411 (2004).
    • (2004) Infect. Immun , vol.72 , Issue.4 , pp. 2408-2411
    • Gibson, F.C.1    Gonzalez, D.A.2    Wong, J.3    Genco, C.A.4
  • 21
    • 0030631850 scopus 로고    scopus 로고
    • Porphyromonas gingivalis proteinases as virulence factors in the development of periodontitis
    • Travis J, Pike R, Imamura T, Potempa J. Porphyromonas gingivalis proteinases as virulence factors in the development of periodontitis. J. Periodontal Res. 32(1 Pt 2), 120-125 (1997).
    • (1997) J. Periodontal Res , vol.32 , Issue.1 PART 2 , pp. 120-125
    • Travis, J.1    Pike, R.2    Imamura, T.3    Potempa, J.4
  • 22
    • 0027965730 scopus 로고
    • Purification and characterization of a novel arginine-specific cysteine protease (argingipain) involved in the pathogenesis of periodontal disease from the culture supernatant of Porphyromonas gingivalis
    • Kadowaki T, Yoneda M, Okamoto K, Maeda K, Yamamoto K. Purification and characterization of a novel arginine-specific cysteine protease (argingipain) involved in the pathogenesis of periodontal disease from the culture supernatant of Porphyromonas gingivalis. J. Biol. Chem. 269(33), 21371-21378 (1994).
    • (1994) J. Biol. Chem , vol.269 , Issue.33 , pp. 21371-21378
    • Kadowaki, T.1    Yoneda, M.2    Okamoto, K.3    Maeda, K.4    Yamamoto, K.5
  • 23
    • 0037261991 scopus 로고    scopus 로고
    • The role of gingipains in the pathogenesis of periodontal disease
    • Imamura T. The role of gingipains in the pathogenesis of periodontal disease. J. Periodontol. 74(1), 111-118 (2003).
    • (2003) J. Periodontol , vol.74 , Issue.1 , pp. 111-118
    • Imamura, T.1
  • 24
    • 0029870771 scopus 로고    scopus 로고
    • Activation of complement component C5 by cysteine proteases from Porphyromonas gingivalis. Prior oxidation of C5 augments proteinase digestion of C5
    • Discipio RG, Daffern PJ, Kawahara M, Pike R, Travis J, Hugli TE. Activation of complement component C5 by cysteine proteases from Porphyromonas gingivalis. Prior oxidation of C5 augments proteinase digestion of C5. Immunology 87(4), 660-667 (1996).
    • (1996) Immunology , vol.87 , Issue.4 , pp. 660-667
    • Discipio, R.G.1    Daffern, P.J.2    Kawahara, M.3    Pike, R.4    Travis, J.5    Hugli, T.E.6
  • 25
    • 0035192042 scopus 로고    scopus 로고
    • Prevention of Porphyromonas gingivalis induced oral bone loss following immunization with gingipain R1
    • Gibson FC, Genco CA. Prevention of Porphyromonas gingivalis induced oral bone loss following immunization with gingipain R1. Infect. Immun. 69(12), 7959-7963 (2001).
    • (2001) Infect. Immun , vol.69 , Issue.12 , pp. 7959-7963
    • Gibson, F.C.1    Genco, C.A.2
  • 26
    • 0036117913 scopus 로고    scopus 로고
    • Immunization with the RgpA-Kgp proteinase-adhesin complexes of Porphyromonas gingivalis protects against periodontal bone loss in the rat periodontitis model
    • Rajapakse PS, O'Brien-Simpson NM, Slakeski N, Hoffmann B, Reynolds EC. Immunization with the RgpA-Kgp proteinase-adhesin complexes of Porphyromonas gingivalis protects against periodontal bone loss in the rat periodontitis model. Infect. Immun. 70(5), 2480-2486 (2002).
    • (2002) Infect. Immun , vol.70 , Issue.5 , pp. 2480-2486
    • Rajapakse, P.S.1    O'Brien-Simpson, N.M.2    Slakeski, N.3    Hoffmann, B.4    Reynolds, E.C.5
  • 28
    • 0345329357 scopus 로고    scopus 로고
    • Antibody response of periodontitis patients to gingipains of Porphyromonas gingivalis
    • Inagaki S, Ishihara K, Takahashi J, Yasaki Y, Yamada S, Okuda K. Antibody response of periodontitis patients to gingipains of Porphyromonas gingivalis. J. Periodontol. 74(10), 1432-1439 (2003).
    • (2003) J. Periodontol , vol.74 , Issue.10 , pp. 1432-1439
    • Inagaki, S.1    Ishihara, K.2    Takahashi, J.3    Yasaki, Y.4    Yamada, S.5    Okuda, K.6
  • 29
    • 0031690172 scopus 로고    scopus 로고
    • A peptide domain on gingipain R which confers immunity against Porphyromonas gingivalis infection in mice
    • Genco CA, Odusanya BM, Potempa J, Mikolajczyk-Pawlinska J, Travis J. A peptide domain on gingipain R which confers immunity against Porphyromonas gingivalis infection in mice. Infect. Immun. 66(9), 4108-4114 (1998).
    • (1998) Infect. Immun , vol.66 , Issue.9 , pp. 4108-4114
    • Genco, C.A.1    Odusanya, B.M.2    Potempa, J.3    Mikolajczyk-Pawlinska, J.4    Travis, J.5
  • 30
    • 0033932230 scopus 로고    scopus 로고
    • RgpA-Kgp peptide based immunogens provide protection against Porphyromonas gingivalis challenge in a murine lesion model
    • O'Brien-Simpson NM, Paolini RA, Reynolds EC. RgpA-Kgp peptide based immunogens provide protection against Porphyromonas gingivalis challenge in a murine lesion model. Infect. Immun. 68(7), 4055-4063 (2000).
    • (2000) Infect. Immun , vol.68 , Issue.7 , pp. 4055-4063
    • O'Brien-Simpson, N.M.1    Paolini, R.A.2    Reynolds, E.C.3
  • 31
    • 0035055831 scopus 로고    scopus 로고
    • Specific antibodies to Porphyromonas gingivalis Lysgingipain by DNA vaccination inhibit bacterial binding to hemoglobin and protect mice from infection
    • Kuboniwa M, Amano A, Shizukuishi S, Nakagawa I, Hamada S. Specific antibodies to Porphyromonas gingivalis Lysgingipain by DNA vaccination inhibit bacterial binding to hemoglobin and protect mice from infection. Infect. Immun. 69(5), 2972-2979 (2001).
    • (2001) Infect. Immun , vol.69 , Issue.5 , pp. 2972-2979
    • Kuboniwa, M.1    Amano, A.2    Shizukuishi, S.3    Nakagawa, I.4    Hamada, S.5
  • 32
    • 24744447203 scopus 로고    scopus 로고
    • An immune response directed to proteinase and adhesin functional epitopes protects against Porphyromonas gingivalis-induced periodontal bone loss
    • O'Brien-Simpson NM, Pathirana RD, Paolini RA et al. An immune response directed to proteinase and adhesin functional epitopes protects against Porphyromonas gingivalis-induced periodontal bone loss. J. Immunol. 175(6), 3980-3989 (2005).
    • (2005) J. Immunol , vol.175 , Issue.6 , pp. 3980-3989
    • O'Brien-Simpson, N.M.1    Pathirana, R.D.2    Paolini, R.A.3
  • 33
    • 0031766801 scopus 로고    scopus 로고
    • Life below the gum line: Pathogenic mechanisms of Porphyromonas gingivalis
    • Lamont RJ, Jenkinson HF. Life below the gum line: pathogenic mechanisms of Porphyromonas gingivalis. Microbiol. Mol. Biol. Rev. 62(4), 1244-1263 (1998).
    • (1998) Microbiol. Mol. Biol. Rev , vol.62 , Issue.4 , pp. 1244-1263
    • Lamont, R.J.1    Jenkinson, H.F.2
  • 34
    • 0029859355 scopus 로고    scopus 로고
    • Isolation and characterization of a minor fimbria from Porphyromonas gingivalis
    • Hamada N, Sojar HT, Cho MI, Genco RJ. Isolation and characterization of a minor fimbria from Porphyromonas gingivalis. Infect. Immun. 64(11), 4788-4794 (1996).
    • (1996) Infect. Immun , vol.64 , Issue.11 , pp. 4788-4794
    • Hamada, N.1    Sojar, H.T.2    Cho, M.I.3    Genco, R.J.4
  • 35
    • 0029056596 scopus 로고
    • Immunochemical characterization and epitope mapping of a novel fimbrial protein (Pg-II fimbria) of Porphyromonas gingivalis
    • Ogawa T, Yasuda K, Yamada K, Mori H, Ochiai K, Hasegawa M. Immunochemical characterization and epitope mapping of a novel fimbrial protein (Pg-II fimbria) of Porphyromonas gingivalis. FEMS Immunol. Med. Microbiol. 11(3), 247-255 (1995).
    • (1995) FEMS Immunol. Med. Microbiol , vol.11 , Issue.3 , pp. 247-255
    • Ogawa, T.1    Yasuda, K.2    Yamada, K.3    Mori, H.4    Ochiai, K.5    Hasegawa, M.6
  • 36
    • 0026647793 scopus 로고
    • Immunization with Porphyromonas (Bacteroides) gingivalis fimbriae protects against periodontal destruction
    • Evans RT, Klausen B, Sojar HT, Bedi GS, Sfintescu C, Ramamurthy NS. Immunization with Porphyromonas (Bacteroides) gingivalis fimbriae protects against periodontal destruction. Infect. Immun. 60(7), 2926-2935 (1992).
    • (1992) Infect. Immun , vol.60 , Issue.7 , pp. 2926-2935
    • Evans, R.T.1    Klausen, B.2    Sojar, H.T.3    Bedi, G.S.4    Sfintescu, C.5    Ramamurthy, N.S.6
  • 37
    • 0029245902 scopus 로고
    • The impact of gene therapy on dentistry
    • Baum BJ, O'Connell BC. The impact of gene therapy on dentistry. J. Am. Dent. Assoc. 126(2), 179-189 (1995).
    • (1995) J. Am. Dent. Assoc , vol.126 , Issue.2 , pp. 179-189
    • Baum, B.J.1    O'Connell, B.C.2
  • 38
    • 0035007533 scopus 로고    scopus 로고
    • Fimbriae of Porphyromonas gingivalis induce opsonic antibodies that significantly enhance phagocytosis and killing by human polymorphonuclear leukocytes
    • Fan Q, Sim ST, Sojar H, Genco R, Page RC. Fimbriae of Porphyromonas gingivalis induce opsonic antibodies that significantly enhance phagocytosis and killing by human polymorphonuclear leukocytes. Oral Microbiol. Immunol. 16(3), 144-152 (2001).
    • (2001) Oral Microbiol. Immunol , vol.16 , Issue.3 , pp. 144-152
    • Fan, Q.1    Sim, S.T.2    Sojar, H.3    Genco, R.4    Page, R.C.5
  • 39
    • 0031984946 scopus 로고    scopus 로고
    • Capsular polysaccharide-fimbrial protein conjugate vaccine protects against Porphyromonas gingivalis infection in SCID mice reconstituted with human peripheral blood lymphocytes
    • Choi JI, Schifferle RE, Yoshimura F, Kim BW. Capsular polysaccharide-fimbrial protein conjugate vaccine protects against Porphyromonas gingivalis infection in SCID mice reconstituted with human peripheral blood lymphocytes. Infect. Immun. 66(1), 391-393 (1998).
    • (1998) Infect. Immun , vol.66 , Issue.1 , pp. 391-393
    • Choi, J.I.1    Schifferle, R.E.2    Yoshimura, F.3    Kim, B.W.4
  • 40
    • 0037380739 scopus 로고    scopus 로고
    • Immunization with Porphyromonas gingivalis capsular polysaccharide prevents Porphyromonas gingivalis elicited oral bone loss in a murine model
    • Gonzalez D, Tzianabos AO, Genco CA, Gibson FC. Immunization with Porphyromonas gingivalis capsular polysaccharide prevents Porphyromonas gingivalis elicited oral bone loss in a murine model. Infect. Immun. 71(4), 2283-2287 (2003).
    • (2003) Infect. Immun , vol.71 , Issue.4 , pp. 2283-2287
    • Gonzalez, D.1    Tzianabos, A.O.2    Genco, C.A.3    Gibson, F.C.4
  • 41
    • 0021400276 scopus 로고
    • Colonization of the subgingival area by Bacteroides gingivalis
    • Takazoe I, Nakamura T, Okuda K. Colonization of the subgingival area by Bacteroides gingivalis. J. Dent. Res. 63(3), 422-426 (1984).
    • (1984) J. Dent. Res , vol.63 , Issue.3 , pp. 422-426
    • Takazoe, I.1    Nakamura, T.2    Okuda, K.3
  • 42
    • 0017862133 scopus 로고
    • Attachment of Bacteroides melaninogenicus subspecies asaccharolyticus to oral surfaces and its possible role in colonization of the mouth and of periodontal pockets
    • Slots J, Gibbons RJ. Attachment of Bacteroides melaninogenicus subspecies asaccharolyticus to oral surfaces and its possible role in colonization of the mouth and of periodontal pockets. Infect. Immun. 19(1), 254-264 (1978).
    • (1978) Infect. Immun , vol.19 , Issue.1 , pp. 254-264
    • Slots, J.1    Gibbons, R.J.2
  • 43
    • 0024579724 scopus 로고
    • Immunochemical identification and preliminary characterization of a nonfimbrial hemagglutinating adhesin of Bacteroides gingivalis
    • Mouton C, Bouchard D, Deslauriers M, Lamonde L. Immunochemical identification and preliminary characterization of a nonfimbrial hemagglutinating adhesin of Bacteroides gingivalis. Infect. Immun. 57(2), 566-573 (1989).
    • (1989) Infect. Immun , vol.57 , Issue.2 , pp. 566-573
    • Mouton, C.1    Bouchard, D.2    Deslauriers, M.3    Lamonde, L.4
  • 44
    • 0024524281 scopus 로고
    • Bacteroides gingivalis vesicles bind to and aggregate Actinomyces viscosus
    • Ellen RP, Grove DA. Bacteroides gingivalis vesicles bind to and aggregate Actinomyces viscosus. Infect. Immun. 57(5), 1618-1620 (1989).
    • (1989) Infect. Immun , vol.57 , Issue.5 , pp. 1618-1620
    • Ellen, R.P.1    Grove, D.A.2
  • 45
    • 0014927492 scopus 로고
    • Interbacterial aggregation of plaque bacteria
    • Gibbons RJ, Nygaard M. Interbacterial aggregation of plaque bacteria. Arch. Oral Biol. 15(12), 1397-1400 (1970).
    • (1970) Arch. Oral Biol , vol.15 , Issue.12 , pp. 1397-1400
    • Gibbons, R.J.1    Nygaard, M.2
  • 46
    • 14744285581 scopus 로고    scopus 로고
    • Transcutaneous immunization with a 40-kDa outer membrane protein of Porphyromonas gingivalis induces specific antibodies which inhibit co-aggregation by Porphyromonas gingivalis
    • Maeba S, Otake S, Namikoshi J, Shibata Y, Hayakawa M, Abiko Y, Yamamoto M. Transcutaneous immunization with a 40-kDa outer membrane protein of Porphyromonas gingivalis induces specific antibodies which inhibit co-aggregation by Porphyromonas gingivalis. Vaccine 23(19), 2513-2521 (2005).
    • (2005) Vaccine , vol.23 , Issue.19 , pp. 2513-2521
    • Maeba, S.1    Otake, S.2    Namikoshi, J.3    Shibata, Y.4    Hayakawa, M.5    Abiko, Y.6    Yamamoto, M.7
  • 47
    • 0242628062 scopus 로고    scopus 로고
    • Specific antibodies induced by nasally administered 40-kDa outer membrane protein of Porphyromonas gingivalis inhibits co-aggregation activity of P. gingivalis
    • Namikoshi Y, Otake S, Maeba S, Hayakawa M, Abiko Y, Yamamoto M. Specific antibodies induced by nasally administered 40-kDa outer membrane protein of Porphyromonas gingivalis inhibits co-aggregation activity of P. gingivalis. Vaccine 22(2), 250-256 (2003).
    • (2003) Vaccine , vol.22 , Issue.2 , pp. 250-256
    • Namikoshi, Y.1    Otake, S.2    Maeba, S.3    Hayakawa, M.4    Abiko, Y.5    Yamamoto, M.6
  • 48
    • 0030958453 scopus 로고    scopus 로고
    • Inhibition of a Porphyromonas gingivalis colonization factor between Actinomyces viscous ATCC19246 by monoclonal antibodies against recombinant 40-kDa outer membrane protein
    • Saito S, Hiratsuka K, Hayakawa M, Takiguchi H, Abiko Y. Inhibition of a Porphyromonas gingivalis colonization factor between Actinomyces viscous ATCC19246 by monoclonal antibodies against recombinant 40-kDa outer membrane protein. Gen. Pharmacol. 28(5), 675-680 (1997).
    • (1997) Gen. Pharmacol , vol.28 , Issue.5 , pp. 675-680
    • Saito, S.1    Hiratsuka, K.2    Hayakawa, M.3    Takiguchi, H.4    Abiko, Y.5
  • 49
    • 0030983941 scopus 로고    scopus 로고
    • A human monoclonal antibody which inhibits the co-aggregation activity of Porphyromonas gingivalis
    • Abiko Y, Ogura N, Matsuda U, Yanagi K, Takiguchi H. A human monoclonal antibody which inhibits the co-aggregation activity of Porphyromonas gingivalis. Infect. Immun. 65(9), 3966-3969 (1997).
    • (1997) Infect. Immun , vol.65 , Issue.9 , pp. 3966-3969
    • Abiko, Y.1    Ogura, N.2    Matsuda, U.3    Yanagi, K.4    Takiguchi, H.5
  • 50
    • 0033145624 scopus 로고    scopus 로고
    • Opsonophagocytic effect of antibody against recombinant conserved 40-kDa outer membrane protein of Porphyromonas gingivalis
    • Saito S, Hayakawa M, Takiguchi H, Abiko Y. Opsonophagocytic effect of antibody against recombinant conserved 40-kDa outer membrane protein of Porphyromonas gingivalis. J. Periodontol. 70(6), 610-617 (1999).
    • (1999) J. Periodontol , vol.70 , Issue.6 , pp. 610-617
    • Saito, S.1    Hayakawa, M.2    Takiguchi, H.3    Abiko, Y.4
  • 51
    • 0035919532 scopus 로고    scopus 로고
    • Identification of vaccine candidate antigens from a genomic analysis of Porphyromonas gingivalis
    • Ross BC, Czajkowski L, Hocking D et al. Identification of vaccine candidate antigens from a genomic analysis of Porphyromonas gingivalis. Vaccine 19(30), 4135-4142 (2001).
    • (2001) Vaccine , vol.19 , Issue.30 , pp. 4135-4142
    • Ross, B.C.1    Czajkowski, L.2    Hocking, D.3
  • 52
    • 0347763682 scopus 로고    scopus 로고
    • Characterization of two outer membrane protein antigens of Porphyromonas gingivalis that are protective in a murine lesion model
    • Ross BC, Czajkowski L, Vandenberg KL, Camuglia S, Woods J, Agius C. Characterization of two outer membrane protein antigens of Porphyromonas gingivalis that are protective in a murine lesion model. Oral Microbiol. Immunol. 19(1), 6-15 (2004).
    • (2004) Oral Microbiol. Immunol , vol.19 , Issue.1 , pp. 6-15
    • Ross, B.C.1    Czajkowski, L.2    Vandenberg, K.L.3    Camuglia, S.4    Woods, J.5    Agius, C.6
  • 53
    • 0025793606 scopus 로고
    • Hemolytic activity in the periodontopathogen Porphyromonas gingivalis kinetics of enzyme release and localization
    • Chu L, Bramanti TE, Ebersole JL, Holt SC. Hemolytic activity in the periodontopathogen Porphyromonas gingivalis kinetics of enzyme release and localization. Infect. Immun. 59(6), 1932-1940 (1991).
    • (1991) Infect. Immun , vol.59 , Issue.6 , pp. 1932-1940
    • Chu, L.1    Bramanti, T.E.2    Ebersole, J.L.3    Holt, S.C.4
  • 54
    • 0023940806 scopus 로고
    • Protective efficacy of active and passive immunizations against experimental infection in ligated hamsters
    • Okuda K, Kato T, Naito Y, Takazoe I, Kikuchi Y, Nakamura T. Protective efficacy of active and passive immunizations against experimental infection in ligated hamsters. J. Dent. Res. 67(5), 807-811 (1988).
    • (1988) J. Dent. Res , vol.67 , Issue.5 , pp. 807-811
    • Okuda, K.1    Kato, T.2    Naito, Y.3    Takazoe, I.4    Kikuchi, Y.5    Nakamura, T.6
  • 55
    • 0030068076 scopus 로고    scopus 로고
    • Passive immunization with monoclonal antibodies against Porphyromonas gingivalis in patients with periodontitis
    • Booth V, Ashley FP, Lehner T. Passive immunization with monoclonal antibodies against Porphyromonas gingivalis in patients with periodontitis. Infect. Immun. 64(2), 422-427 (1996).
    • (1996) Infect. Immun , vol.64 , Issue.2 , pp. 422-427
    • Booth, V.1    Ashley, F.P.2    Lehner, T.3
  • 56
    • 0030632343 scopus 로고    scopus 로고
    • Characterization of the Porphyromonas gingivalis antigen recognized by a monoclonal antibody which prevents colonization by the organism
    • Booth V, Lehner T. Characterization of the Porphyromonas gingivalis antigen recognized by a monoclonal antibody which prevents colonization by the organism. J. Periodontal Res. 32(1 Pt 1), 54-60 (1997).
    • (1997) J. Periodontal Res , vol.32 , Issue.1 PART 1 , pp. 54-60
    • Booth, V.1    Lehner, T.2
  • 57
    • 0031949428 scopus 로고    scopus 로고
    • Construction of a functional ScFv antibody against a hemagglutinin from Porphyromonas gingivalis
    • Shibata Y, Kurihara K, Takiguchi H, Abiko Y. Construction of a functional ScFv antibody against a hemagglutinin from Porphyromonas gingivalis. Infect. Immun. 66(5), 2207-2312 (1998).
    • (1998) Infect. Immun , vol.66 , Issue.5 , pp. 2207-2312
    • Shibata, Y.1    Kurihara, K.2    Takiguchi, H.3    Abiko, Y.4
  • 58
    • 0035319019 scopus 로고    scopus 로고
    • Monoclonal antibody against Porphyromonas gingivalis hemagglutinin inhibits hemolytic activity
    • Hosogi Y, Hayakawa M, Abiko Y. Monoclonal antibody against Porphyromonas gingivalis hemagglutinin inhibits hemolytic activity. Eur. J. Oral Sci. 109(2), 109-113 (2001).
    • (2001) Eur. J. Oral Sci , vol.109 , Issue.2 , pp. 109-113
    • Hosogi, Y.1    Hayakawa, M.2    Abiko, Y.3
  • 59
    • 0037261954 scopus 로고    scopus 로고
    • Human monoclonal antibody inhibits Porphyromonas gingivalis hemagglutinin activity
    • Kaizuka K, Hosogi Y, Hayakawa M, Shibata Y, Abiko Y. Human monoclonal antibody inhibits Porphyromonas gingivalis hemagglutinin activity. J. Periodontol. 74(1), 38-43 (2003).
    • (2003) J. Periodontol , vol.74 , Issue.1 , pp. 38-43
    • Kaizuka, K.1    Hosogi, Y.2    Hayakawa, M.3    Shibata, Y.4    Abiko, Y.5
  • 60
    • 18944377314 scopus 로고    scopus 로고
    • Construction of novel human monoclonal antibodies neutralizing Porphyromonas gingivalis hemagglutination activity using transgenic mice expressing human Ig loci
    • Shibata Y, Hosogi Y, Hayakawa M, Hori N, Kamada M, Abiko Y. Construction of novel human monoclonal antibodies neutralizing Porphyromonas gingivalis hemagglutination activity using transgenic mice expressing human Ig loci. Vaccine 23(29), 3850-3856 (2005).
    • (2005) Vaccine , vol.23 , Issue.29 , pp. 3850-3856
    • Shibata, Y.1    Hosogi, Y.2    Hayakawa, M.3    Hori, N.4    Kamada, M.5    Abiko, Y.6
  • 61
    • 25144508958 scopus 로고    scopus 로고
    • Effectiveness of the B subunit of cholera toxin in potentiating immune responses to the recombinant hemagglutinin/adhesin domain of the gingipain Kgp from Porphyromonas gingivalis
    • Zhang P, Yang QB, Balkovetz DF et al. Effectiveness of the B subunit of cholera toxin in potentiating immune responses to the recombinant hemagglutinin/adhesin domain of the gingipain Kgp from Porphyromonas gingivalis. Vaccine 23(39), 4734-4744 (2005).
    • (2005) Vaccine , vol.23 , Issue.39 , pp. 4734-4744
    • Zhang, P.1    Yang, Q.B.2    Balkovetz, D.F.3
  • 62
    • 0028984239 scopus 로고
    • An antiserum to a synthetic fimbrial peptide of Actinobacillus actinomycetemcomitans blocked adhesion of the microorganism
    • Harano K, Yamanaka A, Okuda K. An antiserum to a synthetic fimbrial peptide of Actinobacillus actinomycetemcomitans blocked adhesion of the microorganism. FEMS Microbiol. Lett. 130(2-3), 279-285 (1995).
    • (1995) FEMS Microbiol. Lett , vol.130 , Issue.2-3 , pp. 279-285
    • Harano, K.1    Yamanaka, A.2    Okuda, K.3
  • 64
    • 0034812168 scopus 로고    scopus 로고
    • Protective humoral immunity induced by surface associated material from Actinobacillus actinomycetemcomitans in mice
    • Herminajeng E, Asmara W, Yuswanto, Barid I, Sosroseno W. Protective humoral immunity induced by surface associated material from Actinobacillus actinomycetemcomitans in mice. Microbes Infect. 3(12), 997-1003 (2001).
    • (2001) Microbes Infect , vol.3 , Issue.12 , pp. 997-1003
    • Herminajeng, E.1    Asmara, W.2    Yuswanto3    Barid, I.4    Sosroseno, W.5
  • 65
    • 0021259224 scopus 로고
    • Microbiota of periodontal pockets losing crestal alveolar bone
    • Tanner AC, Socransky SS, Goodson JM. Microbiota of periodontal pockets losing crestal alveolar bone. J. Periodontal Res. 19(3), 279-291 (1984).
    • (1984) J. Periodontal Res , vol.19 , Issue.3 , pp. 279-291
    • Tanner, A.C.1    Socransky, S.S.2    Goodson, J.M.3
  • 66
    • 0031214262 scopus 로고    scopus 로고
    • Characteristics of systemic antibody responses of nonhuman primates to cell envelope and cell wall antigens from periodontal pathogens
    • Cox SE, Holt SC, Ebersole JL. Characteristics of systemic antibody responses of nonhuman primates to cell envelope and cell wall antigens from periodontal pathogens. Oral Microbiol. Immunol. 12(4), 204-211 (1997).
    • (1997) Oral Microbiol. Immunol , vol.12 , Issue.4 , pp. 204-211
    • Cox, S.E.1    Holt, S.C.2    Ebersole, J.L.3
  • 67
    • 0030131170 scopus 로고    scopus 로고
    • Characteristics of systemic antibody responses of nonhuman primates following active immunization with Porphyromonas gingivalis, Prevotella intermedia and Bacteroides fragilis
    • Giardino A, Ebersole JL, Holt SC. Characteristics of systemic antibody responses of nonhuman primates following active immunization with Porphyromonas gingivalis, Prevotella intermedia and Bacteroides fragilis. Oral Microbiol. Immunol. 11(2), 79-87 (1996).
    • (1996) Oral Microbiol. Immunol , vol.11 , Issue.2 , pp. 79-87
    • Giardino, A.1    Ebersole, J.L.2    Holt, S.C.3
  • 68
    • 3142768296 scopus 로고    scopus 로고
    • Modulation of the antibody response by Porphyromonas gingivalis and Fusobacterium nucleatum in a mouse model
    • Gemmell E, Bird PS, Ford PJ et al. Modulation of the antibody response by Porphyromonas gingivalis and Fusobacterium nucleatum in a mouse model. Oral Microbiol. Immunol. 19(4), 247-51 (2004).
    • (2004) Oral Microbiol. Immunol , vol.19 , Issue.4 , pp. 247-251
    • Gemmell, E.1    Bird, P.S.2    Ford, P.J.3
  • 70
    • 33645048219 scopus 로고    scopus 로고
    • Porphyromonas gingivalis heat shock protein Vaccine reduces the alveolar bone loss induced by multiple periodontopathogenic bacteria
    • Lee JY, Yi NN, Kim US, Choi JS, Kim SJ, Choi JI. Porphyromonas gingivalis heat shock protein Vaccine reduces the alveolar bone loss induced by multiple periodontopathogenic bacteria. J. Periodontal Res. 41(1), 10-14 (2006).
    • (2006) J. Periodontal Res , vol.41 , Issue.1 , pp. 10-14
    • Lee, J.Y.1    Yi, N.N.2    Kim, U.S.3    Choi, J.S.4    Kim, S.J.5    Choi, J.I.6
  • 71
    • 0031577592 scopus 로고    scopus 로고
    • Secretion of Porphyromonas gingivalis fimbrillin polypeptides by recombinant Streptococcus gordonii
    • Sharma A, Sojar HT, Hruby DE, Kuramitsu HK, Genco RJ. Secretion of Porphyromonas gingivalis fimbrillin polypeptides by recombinant Streptococcus gordonii. Biochem. Biophys. Res. Commun. 238(2), 313-316 (1997).
    • (1997) Biochem. Biophys. Res. Commun , vol.238 , Issue.2 , pp. 313-316
    • Sharma, A.1    Sojar, H.T.2    Hruby, D.E.3    Kuramitsu, H.K.4    Genco, R.J.5
  • 72
    • 0035055339 scopus 로고    scopus 로고
    • Oral immunization with recombinant Streptococcus gordonii expressing Porphyromonas gingivalis Fim A domains
    • Sharma A, Honma K, Evans TR, Hruby DE. Oral immunization with recombinant Streptococcus gordonii expressing Porphyromonas gingivalis Fim A domains. Infect. Immun. 69(5), 2928-2934 (2001).
    • (2001) Infect. Immun , vol.69 , Issue.5 , pp. 2928-2934
    • Sharma, A.1    Honma, K.2    Evans, T.R.3    Hruby, D.E.4
  • 73
    • 0033984375 scopus 로고    scopus 로고
    • Expression and immunogenicity of hemagglutinin A from Porphyromonas gingivalis in an avirulent Salmonella enterica
    • Kozarov E, Miyashita N, Burks J, Cerveny K. Expression and immunogenicity of hemagglutinin A from Porphyromonas gingivalis in an avirulent Salmonella enterica. Infect. Immun. 68(2), 732-739 (2000).
    • (2000) Infect. Immun , vol.68 , Issue.2 , pp. 732-739
    • Kozarov, E.1    Miyashita, N.2    Burks, J.3    Cerveny, K.4
  • 74
    • 0032794164 scopus 로고    scopus 로고
    • Host response to recombinant hemagglutinin B of Porphyromonas gingivalis in an experiment rat model
    • Katz J, Black KP, Michalek SM. Host response to recombinant hemagglutinin B of Porphyromonas gingivalis in an experiment rat model. Infect. Immun. 67(9), 4352-4359 (1999).
    • (1999) Infect. Immun , vol.67 , Issue.9 , pp. 4352-4359
    • Katz, J.1    Black, K.P.2    Michalek, S.M.3
  • 76
    • 0034608370 scopus 로고    scopus 로고
    • Receptor-mediated uptake of antigen/heat shock protein complexes class 1 antigen presentation via two distinct processing pathways
    • Castellino F, Boucher PE, Eichelberg K. Receptor-mediated uptake of antigen/heat shock protein complexes class 1 antigen presentation via two distinct processing pathways. J. Exp. Med. 191(11), 1957-1964 (2000).
    • (2000) J. Exp. Med , vol.191 , Issue.11 , pp. 1957-1964
    • Castellino, F.1    Boucher, P.E.2    Eichelberg, K.3
  • 77
    • 0034082268 scopus 로고    scopus 로고
    • Prevaccination with SRL172 (heat-killed Mycobacterium vaccae) inhibits experimental periodontal disease in wistar rats
    • Breivik T, Rook GA. Prevaccination with SRL172 (heat-killed Mycobacterium vaccae) inhibits experimental periodontal disease in wistar rats. Clin. Exp. Immunol. 120(3), 463-467 (2000).
    • (2000) Clin. Exp. Immunol , vol.120 , Issue.3 , pp. 463-467
    • Breivik, T.1    Rook, G.A.2
  • 78
    • 0036595373 scopus 로고    scopus 로고
    • Treatment with SRL172 (heat-killed Mycobacterium vaccae) inhibits progression of established experimental periodontal disease in wistar rats
    • Breivik T, Rook GA. Treatment with SRL172 (heat-killed Mycobacterium vaccae) inhibits progression of established experimental periodontal disease in wistar rats. J. Periodontal Res. 37(3), 210-214 (2002).
    • (2002) J. Periodontal Res , vol.37 , Issue.3 , pp. 210-214
    • Breivik, T.1    Rook, G.A.2
  • 79
    • 0346335742 scopus 로고    scopus 로고
    • Oral treatment with SRP299 (killed Mycobacterium vaccae) inhibits experimental periodontal disease in wistar rats
    • Breivik T, Rook GA. Oral treatment with SRP299 (killed Mycobacterium vaccae) inhibits experimental periodontal disease in wistar rats. J. Clin. Periodontol. 30(11), 931-936 (2003).
    • (2003) J. Clin. Periodontol , vol.30 , Issue.11 , pp. 931-936
    • Breivik, T.1    Rook, G.A.2
  • 80
    • 0027531728 scopus 로고
    • Isolation and characterization of a cloned Porphyromonas gingivalis hemagglutinin from an avirulent strain of Salmonella typhimurium
    • Dusek DM, Progulske-Fox A, Whitlock J, Brown TA. Isolation and characterization of a cloned Porphyromonas gingivalis hemagglutinin from an avirulent strain of Salmonella typhimurium. Infect. Immun. 61(3), 940-946 (1993).
    • (1993) Infect. Immun , vol.61 , Issue.3 , pp. 940-946
    • Dusek, D.M.1    Progulske-Fox, A.2    Whitlock, J.3    Brown, T.A.4
  • 81
    • 0028348031 scopus 로고
    • Systemic and mucosal immune responses in mice orally immunized with avirulent Salmonella typhimurium expressing a cloned Porphyromonas gingivalis hemagglutinin
    • Dusek DM, Progulske-Fox A, Brown TA. Systemic and mucosal immune responses in mice orally immunized with avirulent Salmonella typhimurium expressing a cloned Porphyromonas gingivalis hemagglutinin. Infect. Immun. 62(5), 1652-1657 (1994).
    • (1994) Infect. Immun , vol.62 , Issue.5 , pp. 1652-1657
    • Dusek, D.M.1    Progulske-Fox, A.2    Brown, T.A.3
  • 82
    • 0032054425 scopus 로고    scopus 로고
    • Oral immunization with recombinant Salmonella typhimurium expressing a cloned Porphyromonas gingivalis hemagglutinin: Effect of boosting on mucosal, systemic and immunoglobulin G subclass response
    • Kohler JJ, Pathangey LB, Brown TA. Oral immunization with recombinant Salmonella typhimurium expressing a cloned Porphyromonas gingivalis hemagglutinin: effect of boosting on mucosal, systemic and immunoglobulin G subclass response. Oral Microbiol. Immunol. 13(2), 81-88 (1998).
    • (1998) Oral Microbiol. Immunol , vol.13 , Issue.2 , pp. 81-88
    • Kohler, J.J.1    Pathangey, L.B.2    Brown, T.A.3
  • 83
    • 0026080636 scopus 로고
    • Effect of adoptive transfer of cloned Actinobacillus actinomycetemcomitans-specific T helper cells on periodontal disease
    • Yamashita K, Eastcott JW, Taubman MA, Smith DJ, Cox DS. Effect of adoptive transfer of cloned Actinobacillus actinomycetemcomitans-specific T helper cells on periodontal disease. Infect. Immun. 59(4), 1529-1534 (1991).
    • (1991) Infect. Immun , vol.59 , Issue.4 , pp. 1529-1534
    • Yamashita, K.1    Eastcott, J.W.2    Taubman, M.A.3    Smith, D.J.4    Cox, D.S.5
  • 84
    • 0842326268 scopus 로고    scopus 로고
    • Periodontitis vaccine decreases local prostaglandin E2 levels in a primate model
    • Roberts FA, Laura S, Lukehart SA, Mancl LA, Persson R, Page RC. Periodontitis vaccine decreases local prostaglandin E2 levels in a primate model. Infect. Immun. 72(2), 1166-1168 (2004).
    • (2004) Infect. Immun , vol.72 , Issue.2 , pp. 1166-1168
    • Roberts, F.A.1    Laura, S.2    Lukehart, S.A.3    Mancl, L.A.4    Persson, R.5    Page, R.C.6
  • 85
    • 0036084771 scopus 로고    scopus 로고
    • Mechanisms of monophosphoryl lipid A augmentation of host responses to recombinant HagB from Porphyromonas gingivalis
    • Yang QB, Martin M, Michalek SM, Katz J. Mechanisms of monophosphoryl lipid A augmentation of host responses to recombinant HagB from Porphyromonas gingivalis. Infect. Immun. 70(7), 3557-3565 (2002).
    • (2002) Infect. Immun , vol.70 , Issue.7 , pp. 3557-3565
    • Yang, Q.B.1    Martin, M.2    Michalek, S.M.3    Katz, J.4
  • 86
    • 0030934661 scopus 로고    scopus 로고
    • High-tech herbal medicine: Plant-based vaccines
    • Arntzen CJ. High-tech herbal medicine: plant-based vaccines. Nat. Biotechnol. 15(3), 221-222 (1997).
    • (1997) Nat. Biotechnol , vol.15 , Issue.3 , pp. 221-222
    • Arntzen, C.J.1
  • 87
    • 0029035201 scopus 로고
    • Generation and assembly of secretory antibodies in plants
    • Ma JK, Hiatt A, Hein M et al. Generation and assembly of secretory antibodies in plants. Science 268(5211), 716-719 (1995).
    • (1995) Science , vol.268 , Issue.5211 , pp. 716-719
    • Ma, J.K.1    Hiatt, A.2    Hein, M.3
  • 88
    • 0031835622 scopus 로고    scopus 로고
    • Characterization of a recombinant plant monoclonal secretory antibody and preventive immunotherapy in humans
    • Ma JK, Hikmat BY, Wycoff K et al. Characterization of a recombinant plant monoclonal secretory antibody and preventive immunotherapy in humans. Nat. Med. 4(5), 601-606 (1998).
    • (1998) Nat. Med , vol.4 , Issue.5 , pp. 601-606
    • Ma, J.K.1    Hikmat, B.Y.2    Wycoff, K.3
  • 89
    • 33748704710 scopus 로고    scopus 로고
    • Synthesis and assembly of an adjuvanted Porphyromonas gingivalis fimbrial antigen fusion protein in plants
    • Shin EA, Lee JY, Kim TG, Park YK, Langridge WH. Synthesis and assembly of an adjuvanted Porphyromonas gingivalis fimbrial antigen fusion protein in plants. Protein Expr. Purif. 47(1), 99-109 (2006).
    • (2006) Protein Expr. Purif , vol.47 , Issue.1 , pp. 99-109
    • Shin, E.A.1    Lee, J.Y.2    Kim, T.G.3    Park, Y.K.4    Langridge, W.H.5


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