Specific antibodies to Porphyromonas gingivalis lys-gingipain by DNA vaccination inhibit bacterial binding to hemoglobin and protect mice from infection

Infection and Immunity

Volumn 69, Issue 5, 2001, Pages 2972-2979

  Kuboniwa, M ^a   Amano, A ^a   Shizukuishi, S ^a   Nakagawa, I ^a   Hamada, S ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM ANTIBODY; CYSTEINE PROTEINASE; DNA FRAGMENT; DNA VACCINE; GINGIPAIN R; HAPTOGLOBIN; HEMOGLOBIN; IMMUNOGLOBULIN G; LYS GINGIPAIN; PLASMID DNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL INFECTION; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; CONTROLLED STUDY; CROSS REACTION; FEMALE; INFLAMMATION; MOUSE; NONHUMAN; PORPHYROMONAS GINGIVALIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; SURVIVAL RATE; VACCINATION;

ADHESINS, BACTERIAL; ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL ADHESION; BACTERIAL VACCINES; BACTEROIDACEAE INFECTIONS; BLOTTING, WESTERN; CYSTEINE ENDOPEPTIDASES; FEMALE; HEMAGGLUTININS; HEMOGLOBINS; MICE; MICE, INBRED BALB C; PORPHYROMONAS GINGIVALIS; VACCINATION; VACCINES, DNA;

EID: 0035055831     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.5.2972-2979.2001     Document Type: Article

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