High frequency of recombination-driven allelic diversity and temporal variation of Plasmodium falciparum msp1 in Tanzania

American Journal of Tropical Medicine and Hygiene

Volumn 76, Issue 6, 2007, Pages 1037-1045

  Tanabe, Kazuyuki ^a   Sakihama, Naoko ^a   Rooth, Ingegerd ^b   Björkman, Anders ^c   Färnert, Anna ^c  

^a OSAKA UNIVERSITY   (Japan)

^b Nyamisati Malaria Research Unit   (Tanzania)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

MEROZOITE SURFACE PROTEIN 1; PROTOZOAL DNA;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; GENETIC POLYMORPHISM; GENETIC RECOMBINATION; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; INFANT; NONHUMAN; PARASITE TRANSMISSION; PLASMODIUM FALCIPARUM; PROTOZOAL GENETICS; SEQUENCE ANALYSIS; TANZANIA; ALLELE; ANIMAL; CHEMISTRY; GENE LINKAGE DISEQUILIBRIUM; GENETICS; IMMUNOLOGY; MALARIA FALCIPARUM; MIDDLE AGED; PARASITOLOGY; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PROTEIN MOTIF; RURAL POPULATION;

ANOPHELES (GENUS); PLASMODIUM FALCIPARUM;

ADOLESCENT; ADULT; AGED; ALLELES; AMINO ACID MOTIFS; ANIMALS; CHILD; CHILD, PRESCHOOL; DNA, PROTOZOAN; HAPLOTYPES; HUMANS; INFANT; LINKAGE DISEQUILIBRIUM; MALARIA, FALCIPARUM; MEROZOITE SURFACE PROTEIN 1; MIDDLE AGED; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RECOMBINATION, GENETIC; RURAL POPULATION; TANZANIA;

EID: 34548029206     PISSN: 00029637     EISSN: None     Source Type: Journal    
DOI: 10.4269/ajtmh.2007.76.1037     Document Type: Article

References (37)

1. Holder AA, Guevara Patino JA, Uthaipibull C, Syed SE, Ling IT, Scott-Finnigan T, Blackman MJ, 1999. Merozoite surface protein 1, immune evasion, and vaccine against asexual blood stage malaria. Parassitologia 41: 409-414.
2. Mahanty S, Saul A, Miller LH, 2003. Progress in the development of recombinant and synthetic blood-stage malaria vaccines. J Exp Biol 206: 3781-3788.
3. Conway DJ, Cavanagh DR, Tanabe K, Roper C, Mikes ZS, Sakihama N, Bojang KA, Oduola AMJ, Kremsner PG, Arnot DE, Greenwood BM, McBride JS, 2000. A principal target of human immunity to malaria identified by molecular population genetic and immunological analyses. Nat Med 6: 689-692.
4. Blackman MJ, Ling IT, Nicholls SC, Holder AA, 1991. Proteolytic processing of the Plasmodium falciparum merozoite surface protein-1 produces a membrane-bound fragment containing two epidermal growth factor-like domains. Mol Biochem Parasitol 49: 29-34.
5. Chang SP, Gibson HL, Lee-Ng CT, Barr PJ, Hui GS, 1992. A carboxyl-terminal fragment of Plasmodium falciparum gp195 expressed by a recombinant baculovirus induces antibodies that completely inhibit parasite growth. J Immunol 149: 548-555.
6. Kumar S, Yadava A, Keister DB, Tian JH, Ohl M, Perdue-Greenfield KA, Miller LH, Kaslow DC, 1995. Immunogenicity and in vivo efficacy of recombinant Plasmodium falciparum merozoite surface protein-1 in Aotus monkeys. Mol Med 1: 325-333.
7. Egan AF, Morris J, Barnish G, Allen S, Greenwood BM, Kaslow DC, Holder AA, Riley EM, 1996. Clinical immunity to Plasmodium falciparum malaria is associated with serum antibodies to the 19-kDa C-terminal fragment of the merozoite surface antigen, PfMSP-1. J Inf Dis 173: 765-769.
8. Nwuba R, Sodeinde O, Anumudu C, Omosum Y, Odaibo A, Holder A, Nwagwu M, 2002. The human immune response to Plasmodium falciparum includes both antibodies that inhibit merozoite surface protein 1 secondary processing and blocking antibodies. Infect Immun 70: 5328-5331.
9. 19 are a major component of the invasion-inhibitory response in individuals immune to malaria. J Exp Med 193: 1403-1412.
10. Tanabe K, Mackay M, Goman M, Scaife JG, 1987. Allelic dimorphism in a surface antigen gene of the malaria parasite Plasmodium falciparum. J Mol Biol 195: 273-287.
11. Miller LH, Roberts T, Shahabuddin M, McCutchan TF, 1993. Analysis of genetic diversity in the Plasmodium falciparum merozoite surface protein-1 (MSP1). Mol Biochem Parasitol 59: 1-14.
12. Martinelli A, Cheesman S, Hunt P, Culleton R, Raza A, Mackinnon M, Carter R, 2005. A genetic approach to the de novo identification of targets of strain specific immunity in malaria parasites. Proc Natl Acad Sci USA 102: 814-819.
13. Cheesman S, Raza A, Carter R, 2006. Mixed strain infections and strain-specific protective immunity in the rodent malaria parasite Plasmodium chabaudi chabaudi in mice. Infect Immun 74: 2996-3001.
14. Tanabe K, Sakihama N, Kaneko A, 2004. Stable SNPs in malaria antigen genes in isolated populations. Science 303: 493.
15. Polley SD, Weedal GD, Thomas AW, Golightly LM, Conway DJ, 2005. Orthologous gene sequences of merozoite surface protein 1 (MSP1) from Plasmodium reichenowi and P. gallinaceum confirm an ancient divergence of P. falciparum alleles. Mol Biochem Parasitol 142: 25-31.
16. Ferreira MU, Ribeiro WL, Tonon AP, Kawamoto F, Rich SM, 2003. Sequence diversity and evolution of the malaria vaccine candidate merozoite surface protein-1 (MSP1) of Plasmodium falciparum. Gene 304: 65-75.
17. Snounou G, Zhu X, Siripoon N, Jarra W, Thaithong S, Brown KN, Viriyakosol S, 1999. Biased distribution of msp1 and msp2 allelic variants in Plasmodium falciparum populations in Thailand. Trans R Soc Trop Med Hyg 93: 369-374.
18. Rooth I, Björkman A, 1992. Fever episodes in a holoendemic area of Tanzania: parasitological and clinical findings and diagnostic aspects related to malaria. Trans R Soc Trop Med Hyg 86: 479-482.
19. Hay SI, Rogers DJ, Toomer JF, Snow RW, 2000. Annual Plasmodium falciparum entomological inoculation rates (EIR) across Africa: literature survey, internet access and review. Trans R Soc Trop Med Hyg 94: 113-127.
20. Sakihama N, Ohmae H, Bakote B, Kawabata M, Hirayama K, Tanabe K, 2006. Limited allelic diversity of Plasmodium falciparum msp1 from populations in The Solomon Islands, a highly endemic area. Am J Trop Med Hyg 74: 31-40.
21. Sakihama N, Kimura M, Hirayama K, Kanda T, Na-Bangchang K, Jongwutiwes S, Conway D, Tanabe K, 1999. Allelic recombination and linkage disequilibrium within Msp1 of Plasmodium falciparum, the malignant human malaria parasite. Gene 230: 47-54.
22. Tanabe K, Sakihama N, Färnert A, Rooth I, Björkman A, Walliker D, Ranford-Cartwright L, 2002. In vitro recombination during PCR of Plasmodium falciparum DNA: a potential pitfall in molecular population genetic analysis. Mol Biochem Parasitol 122: 211-216.
23. Qari SH, Shi YP, Goldman IF, Nahlen BL, Tibayrenc M, Lal AA, 1998. Predicted and observed alleles of Plasmodium falciparum merozoite surface protein-1 (MSP-1), a potential malaria vaccine antigen. Mol Biochem Parasitol 92: 241-252.
24. Tanabe K, Sakihama N, Nakamura Y, Kaneko O, Kimura M, Ferreira MU, Hirayama K, 2000. Selection and genetic drift of polymorphisms within the merozoite surface protein-1 gene of Plasmodium falciparum. Gene 241: 325-331.
25. Ferreira MU, Liu Q, Kimura M, Tanabe K, Kawamoto F, 1998. Allelic diversity in the merozoite surface protein-1 and epidemiology of multiple-clone Plasmodium falciparum infections in northern Tanzania. J Parasitol 84: 1286-1289.
26. Babiker H, Walliker D, 1997. Current views on the population structure of Plasmodium falciparum: implications for control. Parasitol Today 13: 262-267.
27. Mu J, Awadalla P, Duan J, McGee KM, Joy DA, McVean GAT, Su AZ, 2005. Recombination hot spots and population structure in Plasmodium falciparum. PLoS Biol 3: 1734-1741.
28. Conway DJ, Roper C, Oduola AM, Arnot DE, Kremsner PG, Grobusch MP, Curtis CF, Greenwood BM, 1999. High recombination rate in natural populations of Plasmodium falciparum. Proc Natl Acad Sci USA 96: 4506-4511.
29. Silva NS, Silveira LA, Machado RL, Povoa MM, Ferreira MU, 2000. Temporal and spatial distribution of the variants of merozoite surface protein-1 (MSP-1) in Plasmodium falciparum populations in Brazil. Ann Trop Med Parasitol 94: 675-688.
30. Beck HP, Felger I, Huber W, Steiger S, Smith T, Weiss N, Alonso P, Tanner M, 1997. Analysis of multiple Plasmodium falciparum infections in Tanzanian children during the phase III trials of the malaria vaccine SPf66. J Inf Dis 175: 921-926.
31. Contamin H, Fandeur T, Rogier C, Bonnefoy S, Trape JF, Mercereau-Puijalon O, 1996. Different genetic characteristics of Plasmodium falciparum isolates collected during successive clinical malaria episodes in Senegalese children. Am J Trop Med Hyg 54: 632-643.
32. Färnert A, Rooth I, Svensson A, Snounou G, Bjorkman A, 1999. Complexity of Plasmodium falciparum infections is consistent over time and protects against clinical disease in Tanzanian children. J Infect Dis 179: 989-995.
33. Woehlbier U, Epp C, Kauth CW, Lutz R, Long CA, Coulibaly B, Kouyaté B, Arevalo-Herrera M, Herrera S, Bujard H, 2006. Analysis of antibodies directed against merozoite surface protein 1 of the human malaria parasite Plasmodium falciparum. Infect Immun 74: 1313-1322.
34. Ekaka MT, Jouin H, Lekoulou F, Issifou S, Mercereau-Puijalon O, Ntoumi F, 2002. Plasmodium falciparum merozoite surface protein 1 (MSP1) genotyping and humoral responses to allele-specific variants. Acta Trop 81: 33-46.
35. Fraser-Hurt N, Felger I, Edoh D, Steiger S, Mashaka M, Masanja H, Smith T, Mbena F, Beck HP, 1999. Effect of insecticide-treated bed nets on haemoglobin values, prevalence and multiplicity of infection with Plasmodium falciparum in a randomized controlled trial in Tanzania. Trans R Soc Trop Med Hyg 93 (Suppl 1): 47-51.
36. Bereczky S, Liljander A, Rooth I, Faraja L, Montgomery SM, Färnert A, 2007. Multiclonal asymptomatic Plasmodium falciparum infections predict a reduced risk of malaria disease in a Tanzanian population. Microbes Infect 9: 103-110.
37. Conway DJ, Greenwood BM, McBride JS, 1992. Longitudinal study of Plasmodium falciparum polymorphic antigens in a malaria-endemic population. Infect Immun 60: 1122-1127.