메뉴 건너뛰기




Volumn 6, Issue 6, 2000, Pages 689-692

A principal target of human immunity to malaria identified by molecular population genetic and immunological analyses

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CHILD; COHORT ANALYSIS; FEMALE; GENE FREQUENCY; GENE LOCUS; GENE SEQUENCE; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALE; MOLECULAR GENETICS; NONHUMAN; PLASMODIUM FALCIPARUM; POPULATION GENETICS; PRIORITY JOURNAL;

EID: 0034095856     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/76272     Document Type: Article
Times cited : (231)

References (37)
  • 1
    • 0029015776 scopus 로고
    • Natural selection on Plasmodium surface proteins
    • Hughes, M. K. & Hughes, A. L. Natural selection on Plasmodium surface proteins. Mol. Biochem. Parasitol. 71, 99-113 (1995).
    • (1995) Mol. Biochem. Parasitol. , vol.71 , pp. 99-113
    • Hughes, M.K.1    Hughes, A.L.2
  • 2
    • 0031036107 scopus 로고    scopus 로고
    • Natural selection on polymorphic malaria antigens and the search for a vaccine
    • Conway, D.J. Natural selection on polymorphic malaria antigens and the search for a vaccine. Parasitol. Today 13, 26-29 (1997).
    • (1997) Parasitol. Today , vol.13 , pp. 26-29
    • Conway, D.J.1
  • 3
    • 0031804948 scopus 로고    scopus 로고
    • Genetic polymorphism and natural selection in the malaria parasite Plasmodium falciparum
    • Escalante, A.A., Lal, A.A. & Ayala, F.J. Genetic polymorphism and natural selection in the malaria parasite Plasmodium falciparum. Genetics 149, 189-202 (1998).
    • (1998) Genetics , vol.149 , pp. 189-202
    • Escalante, A.A.1    Lal, A.A.2    Ayala, F.J.3
  • 4
    • 0027221528 scopus 로고
    • Molecular analysis of an allozyme cline: Alcohol dehydrogenase in Drosophila melanogaster on the east coast of North America
    • Berry, A. & Kreitman, M. Molecular analysis of an allozyme cline: Alcohol dehydrogenase in Drosophila melanogaster on the east coast of North America. Genetics 134, 869-893 (1993).
    • (1993) Genetics , vol.134 , pp. 869-893
    • Berry, A.1    Kreitman, M.2
  • 5
    • 0028879826 scopus 로고
    • A population genetic test of selection at the molecular level
    • Taylor, M.F.J., Shen, Y. & Kreitman, M.E.A population genetic test of selection at the molecular level. Science 270, 1497-1499 (1995).
    • (1995) Science , vol.270 , pp. 1497-1499
    • Taylor, M.F.J.1    Shen, Y.2    Kreitman, M.E.3
  • 6
  • 7
    • 0030467524 scopus 로고    scopus 로고
    • Evaluating loci for use in the genetic analysis of population structure
    • Beaumont, M.A. & Nichols, R.A. Evaluating loci for use in the genetic analysis of population structure. Proc. R. Soc. Lond. B 263, 1619-1626 (1996).
    • (1996) Proc. R. Soc. Lond. B , vol.263 , pp. 1619-1626
    • Beaumont, M.A.1    Nichols, R.A.2
  • 8
    • 0022360581 scopus 로고
    • Primary structure of the precursor to the three major surface antigens of Plasmodium falciparum merozoites
    • Holder, A.A. et al. Primary structure of the precursor to the three major surface antigens of Plasmodium falciparum merozoites. Nature 317, 270-273 (1985).
    • (1985) Nature , vol.317 , pp. 270-273
    • Holder, A.A.1
  • 9
    • 0023159777 scopus 로고
    • Fragments of the polymorphic Mr 185 000 glycoprotein from the surface of isolated Plasmodium falciparum merozoites form an antigenic complex
    • McBride, J.S. & Heidrich, H.-G. Fragments of the polymorphic Mr 185 000 glycoprotein from the surface of isolated Plasmodium falciparum merozoites form an antigenic complex. Mol. Biochem. Parasitol. 23, 71-84 (1987).
    • (1987) Mol. Biochem. Parasitol. , vol.23 , pp. 71-84
    • McBride, J.S.1    Heidrich, H.-G.2
  • 10
    • 0025310377 scopus 로고
    • A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies
    • Blackman, M.J., Heidrich, H.-G., Donachie, S., McBride, J.S. & Holder, A.A. A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies. J. Exp. Med. 172, 379-382 (1990).
    • (1990) J. Exp. Med. , vol.172 , pp. 379-382
    • Blackman, M.J.1    Heidrich, H.-G.2    Donachie, S.3    McBride, J.S.4    Holder, A.A.5
  • 11
    • 2042469348 scopus 로고
    • Merozoite surface coat precursor protein completely protects Aotus monkeys against Plasmodium falciparum malaria
    • Siddiqui, W.A. et al. Merozoite surface coat precursor protein completely protects Aotus monkeys against Plasmodium falciparum malaria. Proc. Natl. Acad. Sci., USA 84, 3014-3018 (1987).
    • (1987) Proc. Natl. Acad. Sci., USA , vol.84 , pp. 3014-3018
    • Siddiqui, W.A.1
  • 12
    • 0021122801 scopus 로고
    • Major surface antigen gene of a human malaria parasite cloned and expressed in bacteria
    • Hall, R. et al. Major surface antigen gene of a human malaria parasite cloned and expressed in bacteria. Nature 311, 379-382 (1984).
    • (1984) Nature , vol.311 , pp. 379-382
    • Hall, R.1
  • 13
    • 0023236613 scopus 로고
    • Allelic dimorphism in a surface antigen gene of the malaria parasite Plasmodium falciparum
    • Tanabe, K., Mackay, M., Goman, M. & Scaife, J.G. Allelic dimorphism in a surface antigen gene of the malaria parasite Plasmodium falciparum. J. Mol. Biol. 195, 273-287 (1987).
    • (1987) J. Mol. Biol. , vol.195 , pp. 273-287
    • Tanabe, K.1    Mackay, M.2    Goman, M.3    Scaife, J.G.4
  • 14
    • 0026536014 scopus 로고
    • Longitudinal study of Plasmodium falciparum polymorphic antigens in a malaria endemic population
    • Conway, D.J., Greenwood, B.M. & McBride, J.S. Longitudinal study of Plasmodium falciparum polymorphic antigens in a malaria endemic population. Infect. Immun. 60, 1122-1127 (1992).
    • (1992) Infect. Immun. , vol.60 , pp. 1122-1127
    • Conway, D.J.1    Greenwood, B.M.2    McBride, J.S.3
  • 15
    • 0031920398 scopus 로고    scopus 로고
    • Stable patterns of allelic diversity at the merozoite surface protein-1 locus of Plasmodium falciparum in clinical isolates from southern Vietnam
    • Ferreira, M.U. et al. Stable patterns of allelic diversity at the merozoite surface protein-1 locus of Plasmodium falciparum in clinical isolates from southern Vietnam. J. Euk. Microbiol. 45, 131-136 (1998).
    • (1998) J. Euk. Microbiol. , vol.45 , pp. 131-136
    • Ferreira, M.U.1
  • 16
    • 0033551061 scopus 로고    scopus 로고
    • High recombination rate in natural populations of Plasmodium falciparum
    • Conway, D.J. et al. High recombination rate in natural populations of Plasmodium falciparum. Proc. Natl. Acad. Sci. USA 96, 4506-4511 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4506-4511
    • Conway, D.J.1
  • 17
    • 0021566877 scopus 로고
    • Estimating F statistics for the analysis of population structure
    • Weir, B.S. & Cockerham, C.C. Estimating F statistics for the analysis of population structure. Evolution 38, 1358-1370 (1984).
    • (1984) Evolution , vol.38 , pp. 1358-1370
    • Weir, B.S.1    Cockerham, C.C.2
  • 18
    • 0029996805 scopus 로고    scopus 로고
    • Towards a high resolution Plasmodium falciparum linkage map: Polymorphic markers from hundreds of simple sequence repeats
    • Su, X.-Z. & Wellems, T.E. Towards a high resolution Plasmodium falciparum linkage map: Polymorphic markers from hundreds of simple sequence repeats. Genomics 33, 430-444 (1996).
    • (1996) Genomics , vol.33 , pp. 430-444
    • Su, X.-Z.1    Wellems, T.E.2
  • 19
    • 0032799007 scopus 로고    scopus 로고
    • Twelve microsatellite markers for characterisation of Plasmodium falciparum from finger prick blood samples
    • Anderson, T.J.C., Su, X.-Z., Bockaire, M., Lagog, M. & Day, K.P. Twelve microsatellite markers for characterisation of Plasmodium falciparum from finger prick blood samples. Parasitology 119, 113-125 (1999).
    • (1999) Parasitology , vol.119 , pp. 113-125
    • Anderson, T.J.C.1    Su, X.-Z.2    Bockaire, M.3    Lagog, M.4    Day, K.P.5
  • 20
    • 0033119186 scopus 로고    scopus 로고
    • Allelic recombination and linkage disequilibrium within Msp-1 of Plasmodium falciparum, the malignant human malaria parasite
    • Sakihama, N. et al. Allelic recombination and linkage disequilibrium within Msp-1 of Plasmodium falciparum, the malignant human malaria parasite. Gene 230, 47-54 (1999).
    • (1999) Gene , vol.230 , pp. 47-54
    • Sakihama, N.1
  • 21
    • 0030272210 scopus 로고    scopus 로고
    • Plasmodium falciparum: gp195 tripeptide repeat-specific monoclonal antibody inhibits parasite growth in vitro
    • Locher, C.P., Tam, L.Q., Chang, S.P., McBride, J.S. & Siddiqui, W.A. Plasmodium falciparum: gp195 tripeptide repeat-specific monoclonal antibody inhibits parasite growth in vitro. Exp. Parasitol. 84, 74-83 (1996).
    • (1996) Exp. Parasitol. , vol.84 , pp. 74-83
    • Locher, C.P.1    Tam, L.Q.2    Chang, S.P.3    McBride, J.S.4    Siddiqui, W.A.5
  • 22
    • 0027241045 scopus 로고
    • Analysis of sequence diversity in the Plasmodium falciparum merozoite surface protein-1 (MSP-1)
    • Miller, L.H., Roberts, T., Shahabuddin, M. & McCutchan, T.F. Analysis of sequence diversity in the Plasmodium falciparum merozoite surface protein-1 (MSP-1). Mol. Biochem. Parasitol. 59, 1-14 (1993).
    • (1993) Mol. Biochem. Parasitol. , vol.59 , pp. 1-14
    • Miller, L.H.1    Roberts, T.2    Shahabuddin, M.3    McCutchan, T.F.4
  • 23
    • 0030890001 scopus 로고    scopus 로고
    • Antigenicity of recombinant proteins derived from Plasmodium falciparum merozoite surface protein 1
    • Cavanagh, D.R. & McBride, J.S. Antigenicity of recombinant proteins derived from Plasmodium falciparum merozoite surface protein 1. Mol. Biochem. Parasitol. 85, 197-211 (1997).
    • (1997) Mol. Biochem. Parasitol. , vol.85 , pp. 197-211
    • Cavanagh, D.R.1    McBride, J.S.2
  • 24
    • 7144229377 scopus 로고    scopus 로고
    • A longitudinal study of type-specific antibody responses to Plasmodium falciparum merozoite surface protein-1 in an area of unstable malaria in Sudan
    • Cavanagh, D.R. et al. A longitudinal study of type-specific antibody responses to Plasmodium falciparum merozoite surface protein-1 in an area of unstable malaria in Sudan. J. Immunol. 161, 347-359 (1998).
    • (1998) J. Immunol. , vol.161 , pp. 347-359
    • Cavanagh, D.R.1
  • 25
    • 0029082106 scopus 로고
    • Efficacy trial of the malaria vaccine SPf66 in Gambian infants
    • D'Alessandro, U. et al. Efficacy trial of the malaria vaccine SPf66 in Gambian infants. Lancet 346, 462-467 (1995).
    • (1995) Lancet , vol.346 , pp. 462-467
    • D'Alessandro, U.1
  • 26
    • 0026773880 scopus 로고
    • Naturally acquired cellular and humoral immune responses to the major merozoite surface antigen (PfMSP1) of Plasmodium falciparum are associated with reduced malaria morbidity
    • Riley, E.M. et al. Naturally acquired cellular and humoral immune responses to the major merozoite surface antigen (PfMSP1) of Plasmodium falciparum are associated with reduced malaria morbidity. Parasite Immunol. 14, 321-337 (1992).
    • (1992) Parasite Immunol. , vol.14 , pp. 321-337
    • Riley, E.M.1
  • 27
    • 0029900423 scopus 로고    scopus 로고
    • Assessment of the role of naturally acquired antibody levels to Plasmodium falciparum merozoite surface protein-1 in protecting Papua New Guinean children from malaria mortality
    • Al-Yaman, F. et al. Assessment of the role of naturally acquired antibody levels to Plasmodium falciparum merozoite surface protein-1 in protecting Papua New Guinean children from malaria mortality. Am. J. Trop. Med. Hyg. 54, 443-448 (1996).
    • (1996) Am. J. Trop. Med. Hyg. , vol.54 , pp. 443-448
    • Al-Yaman, F.1
  • 28
    • 0030047110 scopus 로고    scopus 로고
    • Clinical immunity to Plasmodium falciparum malaria is associated with serum antibodies to the 19kDa C-terminal fragment of the merozoite surface antigen, PfMSP1
    • Egan, A.F. et al. Clinical immunity to Plasmodium falciparum malaria is associated with serum antibodies to the 19kDa C-terminal fragment of the merozoite surface antigen, PfMSP1. J. Infect Dis. 173, 765-769 (1996).
    • (1996) J. Infect Dis. , vol.173 , pp. 765-769
    • Egan, A.F.1
  • 29
    • 0032924514 scopus 로고    scopus 로고
    • Levels of antibody to conserved parts of Plasmodium falciparum merozoite surface protein 1 in Ghanaian children are not associated with protection from clinical malaria
    • Dodoo, D. et al. Levels of antibody to conserved parts of Plasmodium falciparum merozoite surface protein 1 in Ghanaian children are not associated with protection from clinical malaria. Infect. Immun. 67, 2131-2137 (1999).
    • (1999) Infect. Immun. , vol.67 , pp. 2131-2137
    • Dodoo, D.1
  • 30
    • 0033612307 scopus 로고    scopus 로고
    • Solution structure of an EGF module pair from the Plasmodium falciparum merozoite surface protein 1
    • Morgan, W.D. et al. Solution structure of an EGF module pair from the Plasmodium falciparum merozoite surface protein 1. J. Mol. Biol. 289, 113-122 (1999).
    • (1999) J. Mol. Biol. , vol.289 , pp. 113-122
    • Morgan, W.D.1
  • 31
    • 0344717267 scopus 로고    scopus 로고
    • Antibodies that inhibit malaria merozoite surface protein-1 processing and erythrocyte invasion are blocked by naturally acquired human antibodies
    • Patino, J.A., Holder, A.A., McBride, J.S. & Blackman, M.J. Antibodies that inhibit malaria merozoite surface protein-1 processing and erythrocyte invasion are blocked by naturally acquired human antibodies. J. Exp. Med. 186, 1689-1699 (1997).
    • (1997) J. Exp. Med. , vol.186 , pp. 1689-1699
    • Patino, J.A.1    Holder, A.A.2    McBride, J.S.3    Blackman, M.J.4
  • 32
    • 0029894768 scopus 로고    scopus 로고
    • The maintenance of strain structure in populations of recombining infectious agents
    • Gupta, S. et al. The maintenance of strain structure in populations of recombining infectious agents. Nature Med. 2, 437-442 (1996).
    • (1996) Nature Med. , vol.2 , pp. 437-442
    • Gupta, S.1
  • 33
    • 0030066571 scopus 로고    scopus 로고
    • Population genetics and the detection of immunogenic and drug-resistant loci in Plasmodium
    • Hastings, I. Population genetics and the detection of immunogenic and drug-resistant loci in Plasmodium. Parasitol. 112, 155-164 (1996).
    • (1996) Parasitol. , vol.112 , pp. 155-164
    • Hastings, I.1
  • 34
    • 0025800541 scopus 로고
    • The epidemiology of multiple-clone Plasmodium falciparum infections in Gambian patients
    • Conway, D.J., Greenwood, B.M. & McBride, J.S. The epidemiology of multiple-clone Plasmodium falciparum infections in Gambian patients. Parasitology 103, 1-6 (1991).
    • (1991) Parasitology , vol.103 , pp. 1-6
    • Conway, D.J.1    Greenwood, B.M.2    McBride, J.S.3
  • 35
    • 0031148834 scopus 로고    scopus 로고
    • Plasmodium falciparum: Allelic variation in the merozoite surface protein 1 gene in wild isolates from southern Vietnam
    • Kaneko, O., Kimura, M., Kawamoto, F., Ferreira, M.U. & Tanabe, K. Plasmodium falciparum: Allelic variation in the merozoite surface protein 1 gene in wild isolates from southern Vietnam. Exp. Parasitol. 86, 45-57 (1997).
    • (1997) Exp. Parasitol. , vol.86 , pp. 45-57
    • Kaneko, O.1    Kimura, M.2    Kawamoto, F.3    Ferreira, M.U.4    Tanabe, K.5
  • 36
    • 0028296261 scopus 로고
    • Expression of the 19-kilodalton carboxy-terminal fragment of the Plasmodium falciparum merozoite surface protein-1 in Escherichia coli as a correctly folded protein
    • Burghaus, P.A. & Holder, A.A. Expression of the 19-kilodalton carboxy-terminal fragment of the Plasmodium falciparum merozoite surface protein-1 in Escherichia coli as a correctly folded protein. Mol. Biochem. Parasitol. 64, 165-169 (1994).
    • (1994) Mol. Biochem. Parasitol. , vol.64 , pp. 165-169
    • Burghaus, P.A.1    Holder, A.A.2
  • 37
    • 0028939415 scopus 로고
    • Serum antibodies from malaria-exposed people recognize conserved epitopes formed by the two epidermal growth factor motifs of MSP1(19), the carboxy-terminal fragment of the major merozoite surface protein of Plasmodium falciparum
    • Egan, A.F. et al. Serum antibodies from malaria-exposed people recognize conserved epitopes formed by the two epidermal growth factor motifs of MSP1(19), the carboxy-terminal fragment of the major merozoite surface protein of Plasmodium falciparum. Infect. Immun. 63, 456-466 (1995).
    • (1995) Infect. Immun. , vol.63 , pp. 456-466
    • Egan, A.F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.