Depletion of O6-methylguanine-DNA methyltransferase by O 6-benzylguanine enhances 5-FU cytotoxicity in colon and oral cancer cell lines

Oncology Reports

Volumn 17, Issue 6, 2007, Pages 1461-1467

  Murakami, Jun ^a   Lee, You Jin ^b   Kokeguchi, Susumu ^c   Tsujigiwa, Hidetsugu ^c   Asaumi, Jun Ichi ^a   Nagatsuka, Hitoshi ^c   Fukui, Kazuhiro ^c   Kuroda, Masahiro ^c   Tanaka, Noriaki ^c   Matsubara, Nagahide ^c  

^a OKAYAMA UNIVERSITY   (Japan)

^b Chosun University   (South Korea)

^c OKAYAMA UNIVERSITY   (Japan)

Author keywords

5 Fluorouracil

Indexed keywords

ANTINEOPLASTIC AGENT; DRUG DERIVATIVE; ENZYME INHIBITOR; FLUOROURACIL; GUANINE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; O(6) BENZYLGUANINE; O(6)-BENZYLGUANINE; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; COLON TUMOR; DRUG ANTAGONISM; DRUG EFFECT; DRUG RESISTANCE; ENZYMOLOGY; HUMAN; METABOLISM; MOUTH TUMOR; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; DRUG RESISTANCE, NEOPLASM; ENZYME INHIBITORS; FLUOROURACIL; GUANINE; HUMANS; MOUTH NEOPLASMS; O(6)-METHYLGUANINE-DNA METHYLTRANSFERASE;

EID: 34548014313     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.17.6.1461     Document Type: Article

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