Hepatocyte Transplantation from Steatotic Liver in a Rat Model

Journal of Surgical Research

Volumn 142, Issue 1, 2007, Pages 104-112

  Hayashi, Ken ^a   Aoki, Takeshi ^a   Jin, Zhenghao ^a   Wang, Hexian ^a   Nishino, Nobukazu ^a   Kusano, Tomokazu ^a   Yasuda, Daisuke ^a   Koizumi, Tomotake ^a   Enami, Yuta ^a   Odaira, Masanori ^a   Yamada, Kousuke ^a   Mitamura, Keitaro ^a   Niiya, Takashi ^a   Murai, Noriyuki ^a   Kato, Hirohisa ^a   Shimizu, Yoshinori ^a   Kusano, Mitsuo ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

hepatocyte culture; hepatocyte transplantation; steatotic hepatocyte; steatotic liver

Indexed keywords

SERUM ALBUMIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FATTY LIVER; HEPATOCYTE TRANSPLANTATION; LIVER CELL; LIVER TRANSPLANTATION; NONHUMAN; PERIODIC ACID SCHIFF STAIN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ZUCKER RAT;

ALBUMINS; ANIMALS; CELL TRANSPLANTATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FATTY LIVER; HEPATOCYTES; LIVER REGENERATION; MALE; RATS; RATS, ZUCKER; UREA;

EID: 34547955347     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2006.10.048     Document Type: Article

References (39)

1. Neuberger J. Developments in liver transplantation. Gut 53 (2004) 759
2. Neuberger J., and James O. Guidelines for selection of patients for liver transplantation in the era of donor-organ shortage. Lancet 354 (1999) 1636
3. United Network for Organ Sharing. Organ procurement and transplant network. Available at http://www.unos.org/.
4. Fox I.J., and Chowdhury J.R. Hepatocyte transplantation. J Hepatol 40 (2004) 878
5. Kusano M., and Mito M. Observations on the fine structure of long-survived isolated hepatocytes inoculated into rat spleen. Gastroenterology 82 (1982) 616
6. Aoki T., Jin Z., Nishino N., et al. Intrasplenic transplantation of encapsulated hepatocytes decreases mortality and improves liver functions in fulminant hepatic failure from 90% partial hepatectomy in rats. Transplantation 79 (2005) 783
7. Aoki T., Koizumi T., Kobayashi Y., et al. A novel method of cryopreservation of rat and human hepatocytes by using encapsulation technique and possible use for cell transplantation. Cell Transplant 14 (2005) 609
8. Mito M., Kusano M., and Kawaura Y. Hepatocyte transplantation in man. Transplant Proc 24 (1992) 3052
9. Habibullah C.M., Syed I.H., Qamar A., et al. Human fetal hepatocyte transplantation in patients with fulminant hepatic failure. Transplantation 58 (1994) 951
10. Grossman M., Rader D.J., Mullar D., et al. A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolemia. Nature Med 1 (1995) 1148
11. Strom S.C., Fisher R.A., Thompson M.T., et al. Hepatocyte transplantation as a bridge to orthotopic liver transplantation in terminal liver failure. Transplantation 63 (1997) 559
12. Soriano H.E., Wood R.P., Kang D.C., et al. Hepatocellular transplantation (HCT) in children with fulminant liver failure (FLF). Hepatology 26 (1997) 239A (443).
13. Fox I.J., Chowdhury J.R., Kaufman S.S., et al. Treatment of the Crigler-Njjar syndrome type 1 with hepatocyte transplantation. New Engl J Med 338 (1998) 1422
14. Strom S.C., Chowdhury J.R., and Fox I.J. Hepatocyte transplantation for the treatment of human disease. Semin Liver Dis 19 (1999) 39
15. Muraca M., Gerunda G., Neri D., et al. Hepatocyte transplantation as a treatment for glycogen storage disease type 1A. Lancet 359 (2002) 317
16. Sokal E.M., Smets F., Bourgois A., et al. Hepatocyte transplantation in a 4-year-old girl with peroxisomal biogenesis disease: Technique, safety, and metabolic follow-up. Transplantation 76 (2003) 735
17. Todo S., Demetris A.J., Makowka L., et al. Hepatic transplantation in galactosemia. Transplantation 47 (1989) 902
18. D'Alessandro A.M., Kalayoglu M., Sollinger H.W., et al. The predictive value of donor liver biopsies for the development of primary nonfunction after orthotopic liver transplantation. Transplantation 51 (1991) 157
19. Adam R., Reynes M., Johann M., et al. The outcome of steatotic grafts in liver transplantation. Transplant Proc 23 (1991) 1538
20. Ploeg R.J., D'Alessandro A.M., Knechtle S.J., et al. Risk factors for primary dysfunction after liver transplantation-a multivariate analysis. Transplantation 55 (1993) 807
21. Canelo R., Braun F., Sattler B., et al. Is a fatty liver dangerous for transplantation?. Transplant Proc 31 (1999) 414
22. Briceno J., Marchal T., Padillo J., et al. Influence of marginal donors on liver preservation injury. Transplantation 74 (2002) 522
23. Baccarani U., Sanna A., Cariani A., et al. Isolation of human hepatocytes from livers rejected for liver transplantation on a national basis: Results of a 2-year experience. Liver Transplant 9 (2003) 506
24. Seglen P.O. Preparation of isolated rat liver cells. Methods Cell Biol 13 (1976) 29
25. Chomczynski P. A reagent for the single-step simultaneous isolation of RNA, DNA, and proteins from cell and tissue samples. Biotechniques 15 (1993) 532
26. Koneru B., Reddy M.C., Torre A.N., et al. Studies of hepatic warm ischemia in the obese Zucker rat. Transplantation 59 (1995) 942
27. Sun C.K., Zhang X.Y., Zimmermann A., et al. Effect of ischemia-reperfusion injury on the microcirculation of the steatotic liver of the Zucker rat. Transplantation 72 (2001) 1625
28. Cereghini S. Liver-enriched transcription factors and hepatocyte differentiation. FASEB 10 (1996) 267
29. Hayashi M., Tokunaga Y., Fujita T., et al. The effect of cold preservation on steatotic graft viability in rat liver transplantation. Transplantation 56 (1993) 282
30. Teramoto K., Bowers J.L., Kruskal J.B., et al. Hepatic microcirculatory changes after reperfusion in fatty and normal liver transplantation in the rat. Transplantation 56 (1993) 1076
31. Zhong Z., Cornnor H., Stachlewitz R.F., et al. Role of free radicals in primary nonfunction of marginal fatty grafts from rats treated acutely with ethanol. Mol. Pharmacol 52 (1997) 912
32. Fukumori T., Ohkohchi N., Tsukamoto S., et al. The mechanism of injury in a steatotic liver graft during cold preservation. Transplantation 67 (1999) 195
33. Minor T., Akbar S., Tolba R., et al. Cold preservation of fatty liver grafts: Prevention of functional and ultrastructural impairments by venous oxygen persufflation. J Hepatol 32 (2000) 105
34. Herreo M.C., Remesar X., Arola L., et al. Ammonium uptake and urea production in hepatocytes from lean and obese Zuker rats. Mol Cell Biochem 200 (1999) 163
35. Wardlaw G.M., and Kaplan M.L. Oxygen consumption and oxidative capacity of hepatocytes from young male obese and non-obese Zucker rats. Proc Soc Exp Biol Med 183 (1986) 199
36. Brady L.J., and Hoppel C.L. Hepatic mitochondrial function in lean and obese Zucker rats. Am J Physiol 245 (1983) E239
37. Ikebukuro H., Inagaki M., and Mito M. Prolonged function of hepatocytes transplanted into the spleens of Nagase analbuminemic rats. Eur Surg Res 31 (1999) 39
38. Rozga J., Holzman M., Moscioni A.D., et al. Repeated intraportal hepatocyte transplantation in analbuminemic rats. Cell Transplant 4 (1995) 237
39. Cho J.Y., Suh K.S., Kwon C.H., et al. The hepatic regeneration power of mild steatotic grafts is not impaired in living-donor liver transplantation. Liver Transplant 11 (2005) 210