Enantiospecific synthesis of the heparanase inhibitor (+)-trachyspic acid and stereoisomers from a common precursor

Organic and Biomolecular Chemistry

Volumn 5, Issue 17, 2007, Pages 2826-2834

  Zammit, Steven C ^a   Ferro, Vito ^b   Hammond, Edward ^b   Rizzacasa, Mark A ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b Progen Pharmaceuticals Limited   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ENANTIOSPECIFIC SYNTHESIS; EPIMERS; HEPARANASE INHIBITION; STEREOISOMERS; TRACHYSPIC ACID;

DERIVATIVES; ENANTIOSELECTIVITY; ISOMERS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

ENZYME INHIBITION;

BETA GLUCURONIDASE; ENZYME INHIBITOR; HEPARANASE; SPIRO COMPOUND; TRACHYSPIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CYCLIZATION; DRUG ANTAGONISM; METABOLISM; STEREOISOMERISM; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; ENZYME INHIBITORS; GLUCURONIDASE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SPIRO COMPOUNDS; STEREOISOMERISM;

EID: 34547892223     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b708594j     Document Type: Article

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