Endothelin-1 blockade prevents COX2 induction and TXA 2 production in the fructose hypertensive rat

Canadian Journal of Physiology and Pharmacology

Volumn 85, Issue 3-4, 2007, Pages 422-429

  Jiang, Jihong ^a   Tran, Linda ^a   Vasudevan, Harish ^a   Xia, Zhengyuan ^a   Yuen, Violet G ^a   McNeill, John H ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Aorta; Blood pressure; Endothelin 1 (ET 1); Fructose; Insulin resistance; Thromboxane (TXA2)

Indexed keywords

BOSENTAN; CYCLOOXYGENASE 2; DAZMEGREL; ENDOTHELIN 1; FRUCTOSE; THROMBOXANE A2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CONTROLLED STUDY; FEEDING; HYPERTENSION; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALS; BLOOD PRESSURE; CYCLOOXYGENASE 2; ENDOTHELIN-1; FRUCTOSE; HYPERTENSION; IMIDAZOLES; INSULIN; MALE; RATS; RATS, WISTAR; RECEPTORS, ENDOTHELIN; RECEPTORS, THROMBOXANE; SULFONAMIDES; THROMBOXANE A2; THROMBOXANE B2; THROMBOXANE-A SYNTHASE;

EID: 34547872828     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/Y06-088     Document Type: Article

References (39)

1. Baron, A.D. 1996. Insulin and the vasculature-old actors, new roles. J. Investig. Med. 44: 406-412. PMID:8952221.
2. Bhanot, S., and McNeill, J.H. 1996. Insulin and hypertension: a causal relationship? Cardiovasc. Res. 31: 212-221. doi:10.1016/0008-6363(95) 00218-9. PMID:8730395.
3. Buyukgebiz, O., Aktan, A.O., Haklar, G., Bilsel, S., and Dulger, M. 1999. The effects of thromboxane synthase inhibition on reperfusion injury and endothelin-1,2 levels in allograft kidney transplantation in rats. Res. Exp. Med. (Berl.), 198: 289-298. PMID:10369085.
4. D'Angelo, G., Elmarakby, A.A., Pollock, D.M., and Stepp, D.W. 2005. Fructose feeding increases insulin resistance but not blood pressure in Sprague-Dawley rats. Hypertension, 46: 806-811. doi:10.1161/01.HYP. 0000182697.39687.34. PMID:16157789.
5. DeFronzo, R.A., and Ferrannini, E. 1991. Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, hyslipidaemia and atherosclerotic cardiovascular disease. Diabetes Care, 14: 173-194. PMID:2044434.
6. Ferrannini, E. 1991. Metabolic abnormalities of hypertension. A lesson in complexity. Hypertension, 18: 636-639. PMID: 1937667.
7. Ferri, C., Bellini, C., Desideri, G., De Mattia, G., and Santucci, A. 1996, Endogenous insulin modulates circulating endothelin-1 concentrations in humans. Diabetes Care, 19: 504-506. PMID: 8732718.
8. Frank, H.J., Levin, E.R., Hu, R.M., and Pedram, A. 1993. Insulin stimulates endothelin binding and action on cultured vascular smooth muscle cells. Endocrinology, 133: 1092-1097. doi:10. 1210/en.133.3.1092. PMID:8365355.
9. Galipeau, D., Arikawa, E., Sekirov, I., and McNeill, J.H. 2001. Chronic thromboxane synthase inhibition prevents fructose-induced hypertension. Hypertension, 38: 872-876. PMID: 11641301.
10. Galipeau, D., Verma, S., and McNeill, J.H. 2002. Female rats are protected against fructose-induced changes in metabolism and blood pressure. Am. J. Physiol. Heart Circ. Physiol. 283: H2478-H2484. PMID:12427595.
11. Howarth, S.R., Vallance, P., and Wilson, C.A. 1995. Role of thromboxane A2 in the vasoconstrictor response to endothelin-1, angiotensin II and 5-hydroxytryptamine in human placental vessels. Placenta, 16: 679-689. doi:10.1016/0143-4004(95) 90012-8. PMID:8710799.
12. Hu, R.M., Levin, E.R., Pedram, A., and Frank, H.J. 1993. Insulin stimulates production and secretion of endothelin from bovine endothelial cells. Diabetes, 42: 351-358. PMID:8425673.
13. Ishimitsu, T., Uehara, Y., Ishii, M., and Sugimoto, T. 1988. Enhanced generation of vascular thromboxane A2 in spontaneously hypertensive rats and its role in the rapid proliferation of vascular smooth muscle cells. Am. J. Hypertens. 1: 38S-40S. PMID:3415806.
14. Jiang, J., Ballinger, C.A., Wu, Y., Dai, Q., Cyr, D.M., Höhfeld, J., and Patterson, C. 2001. CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation. J. Biol. Chem. 276: 42938-42944. PMID:11557750.
15. Loomis, E.D., Sullivan, J.C., Osmond, D.A., Pollock, D.M., and Pollock, J.S. 2005. Endothelin mediates Superoxide production and vasoconstriction through activation of NADPH oxidase and uncoupled nitric-oxide synthase in the rat aorta. J. Pharmacol. Exp. Ther. 315: 1058-1064. doi:10.1124/jpet.105. 091728. PMID:16144972.
16. Lund, A.K., Peterson, A.L., Timmins, G.S., and Walker, M.K. 2005. Endothelin-1-mediated increase in reactive oxygen species and NADPH oxidase activity in hearts of aryl hydrocarbon receptor (AhR) null mice. Toxicol. Sci. 88: 265-273. doi:10.1093/toxsci/kfi284. PMID:16107552.
17. Matsuda, M., and DeFronzo, R.A. 1999. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care, 22: 1462-1470. PMID:10480510.
18. Mistry, M., and Nasjletti, A. 1989. Role of TXA2 in the pathogenesis of severe angiotensin II-salt hypertension. Adv. Prostaglandin Thromboxane Leukot. Res. 19: 207-210. PMID:2526469.
19. Muck, A.O., Seeger, H., Korte, K., and Lippert, T.H. 1993. The effect of 17 beta-estradiol and endothelin 1 on prostacyclin and thromboxane production in human endothelial cell cultures. Clin. Exp. Obstet. Gynecol. 20: 203-206. PMID: 8281701.
20. Narumiya, S., Sugimoto, Y., and Ushikubi, F. 1999. Prostanoid receptors: structures, properties, and functions. Physiol. Rev. 79: 1193-1226. PMID:10508233.
21. Nedelec, E., Abid, A., Cipolletta, C., Presle, N., Terlain, D., Netter, P., and Jouzeau, J. 2001. Stimulation of cyclooxygenase-2-activity by nitric oxide-derived species in rat chondrocyte: lack of contribution to loss of cartilage anabolism. Biochem. Pharmacol. 61: 965-978. doi:10.1016/80006-2952(01)00559-7. PMID:11286988.
22. Pollock, D.M. 2005. Endothelin, angiotensin and oxidative stress in hypertension. Hypertension, 45: 477-480. doi:10.1161/01.HYP. 0000158262.11935.d0. PMID:15723961.
23. Reaven, G.M. 1991. Relationship between insulin resistance and hypertension. Diabetes Care, 14(Suppl. 4): 33-38. PMID:1748055.
24. Reynolds, E.E., and Mok, L.L. 1990. Role of thromboxane A2/prostaglandin H2 receptor in the vasoconstrictor response of rat aorta to endothelin. J. Pharmacol. Exp. Ther. 252:915-921. PMID:2138670.
25. Schiffrin, E.L. 1998. Endothelin: role in hypertension. Biol. Res. 31: 199-208. PMID:9830507.
26. Smith, W.L., and Marnett, L.J. 1991. Prostaglandin endoperoxide synthase: structure and catalysis. Biochim. Biophys. Acta, 1083: 1-17. PMID:1903304.
27. Song, D., Arikawa, E., Galipeau, D., Battell, M., and McNeill, J.H. 2004. Androgens are necessary for the development of fructose-induced hypertension. Hypertension, 43: 667-672. doi:10.1161/01.HYP.0000118018.77344.4e. PMID:14757778.
28. Stahl, R.A., Helmchen, U., Paravicini, M., Ritter, L.J., and Schollmeyer, P. 1984. Glomerular prostaglandin formation in two-kidney, one-clip hypertensive rats. Am. J. Physiol. 247: F975-F981. PMID:6507633.
29. Touyz, R.M., and Schiffrin, E.L. 2003. Role of endothelin in human hypertension. Can. J. Physiol. Pharmacol. 81: 533-541. doi:10.1139/y03-009. PMID:12839265.
30. Verma, S., and McNeill, J.H. 1999. Insulin resistance and hypertension; pharmacologic and mechanistic studies. Can. J. Diabetes Care, 23: 23-42.
31. Verma, S., Bhanot, S., and McNeill, J.H. 1995. Effect of chronic endothelin blockade in hyperinsulinemic hypertensive rats. Am. J. Physiol. 269: H2017-H2021. PMID:8594911.
32. Verma, S., Bhanot, S., Yao, L., and McNeill, J.H. 1996. Defective endothelium-dependent relaxation in fructose-hypertensive rats. Am. J. Hypertens. 9: 370-376. doi:10.1016/0895-7061(95) 00392-4. PMID:8722439.
33. Verma, S., Skarsgard, P., Bhanot, S., Yao, L., Laher, I., and McNeill, J.H. 1997. Reactivity of mesenteric arteries from fructose hypertensive rats to endothelin-1. Am. J. Hypertens. 10:1010-1019. doi:10.1016/S0895-7061(97) 00107-6. PMID:9324107.
34. Verma, S., Arikawa, E., and McNeill, J.H. 2001. Long-term endothelin receptor blockade improves cardiovascular function in diabetes. Am. J. Hypertens. 14: 679-687. doi:10.1016/S0895 7061(01)01302-4. PMID:11465653.
35. White, L.R., Juul, R., Cappelen, J., and Aasly, J. 2002. Cyclooxygenase inhibitors attenuate endothelin ET(B) receptor-mediated contraction in human temporal artery. Eur. J. Pharmacol. 448: 51-57. doi:10.1016/S0014- 2999(02)01894-0. PMID:12126971.
36. Wu, K.K. 1998. Cyclooxygenase-2 induction in congestive heart failure: friend or foe? Circulation, 98: 95-96. PMID:9679712.
37. Yamashita, W., Ito, Y., Weiss, M.A., Ooi, B.S., and Pollak, V.E. 1988. A thromboxane synthetase antagonist ameliorates progressive renal disease of Dahl-S rats. Kidney Int. 33: 77-83. PMID:2965273.
38. Yanagisawa-Miwa, A., Ito, H., and Sugimoto, T. 1990. Effects of insulin on vasoconstriction induced by thromboxane A2 in porcine coronary artery. Circulation, 81: 1654-1659. PMID:2184947.
39. Zaugg, C.E., Hornstein, P.S., Zhu, P., Simper, D., Luscher, T.F., Allegrini, P.R., and Buser, P.T. 1996. Endothelin-1-induced release of thromboxane A2 increases the vasoconstrictor effect of endothelin-1 in postischemic reperfused rat hearts. Circulation, 94: 742-747. PMID:8772697.