Defective endothelium-dependent relaxation in fructose-hypertensive rats

American Journal of Hypertension

Volumn 9, Issue 4 I, 1996, Pages 370-376

  Verma, Subodh ^a   Bhanot, Sanjay ^a   Yao, Linfu ^a   McNeill, John H ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

endothelial function; fructose hypertension; hyperinsulinemia; insulin resistance

Indexed keywords

FRUCTOSE; INSULIN; NITROPRUSSIDE SODIUM; NORADRENALIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM; HYPERINSULINEMIA; HYPERTENSION; INSULIN RESISTANCE; MALE; MESENTERIC ARTERY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT; VASODILATATION;

EID: 0030009553     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/0895-7061(95)00392-4     Document Type: Article

References (44)

1. Reaven GM: Role of insulin resistance in human disease. Diabetes 1988;37:1495-1507.
2. Zavaroni I, Dall'Aglio IE, Bonora E, et al: Evidence that multiple risk factors for coronary artery disease exist in persons with abnormal glucose tolerance. Am J Med 1987;83:609-612.
3. Bhanot S, McNeill JH, Bryer-Ash M: Vanadyl sulfate prevents fructose-induced hyperinsulinemia and hypertension in rats. Hypertension 1994;23:308-312.
4. Bhanot S, Bryer-Ash M, Cheung A, McNeill JH: Bis (maltolato) oxovanadium (IV) attenuates hyperinsulinemia and hypertension in spontaneously hypertensive rats. Diabetes 1994;43:857-861.
5. Bhanot S, Bryer-Ash M, Michoulas A, McNeill JH: Pioglitazone attenuates hyperinsulinemia and lowers systolic blood pressure in spontaneously hypertensive rats. Can J Physiol Pharmacol 1994;72(suppl 1):P1.9.31.
6. Verma S, Bhanot S, McNeill JH: Metformin decreases plasma insulin levels and blood pressure in spontaneously hypertensive rats. Am J Physiol 1994;36:H1250-1253.
7. Verma S, Bhanot S, McNeill JH: Antihypertensive effects of metformin in fructose-fed hyperinsulinemic, hypertensive rats. J Pharmcol Exp Therap 1994;271: 1334-1337.
8. Laakso M, Edelman SV, Brechtel G, Baron AD: Decreased effect of insulin to stimulate skeletal muscle blood flow in obese men. J Clin Invest 1990;85:1844-1852.
9. Baron AD, Brechtel-Hook G, Johnson A, Hardin D: Skeletal muscle blood flow. A possible link between insulin resistance and blood pressure. Hypertension 1993;21:129-135.
10. Anderson EA, Hoffman RP, Balon TW, et al: Hyperinsulinemia produces both sympathetic neural activation and vasodilation in normal humans. J Clin Invest 1991;87:2246-2252.
11. Creager MA, Liang CS, Coffman JD: Beta adrenergic-mediated vasodilator response to insulin in the human forearm. J Pharmacol Exp Ther 1985;235:709-714.
12. Steinberg HO, Brechtel G, Johnson A, et al: Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent: a novel action of insulin to increase nitric oxide release. J Clin Invest 1994;94:1172-1179.
13. Neahring JM, Stepniakowski K, Greene AS, Egan BM: Insulin does not reduce forearm alpha-vasoreactivity in obese hypertensive or lean normotensive men. Hypertension 1993;22:584-590.
14. Reaven GM, Ho H, Hoffman BB: Somatostatin inhibition of fructose-induced hypertension. Hypertension 1989;14:117-120.
15. Bunag RD: Validation in awake rats of a tail-cuff method for measuring systolic pressure. J Appl Physiol 1973;34:279-282.
16. Hwang IS, Ho H, Hoffmann BB, Reaven GM: Fructose induced insulin resistance and hypertension in rats. Hypertension 1987;10:512-516.
17. Huttner I, Gabbiani G: Vascular endothelium in hypertension, in Genest J, Kuchel O, Hamet P, Cantin M (eds): Hypertension: Physiopathology and Treatment, 2nd ed. McGraw-Hill, New York, 1983, pp 473-488.
18. Lüscher TF, Diederich D, Weber E, et al: Endothelium-dependent responses in carotid and renal arteries of normotensive and hypertensive rats. Hypertension 1988;11:573-578.
19. Lüscher TF, Vanhoutte PM, Raij L: Antihypertensive treatment normalizes decreased endothelium-dependent relaxations in rats with salt-induced hypertension. Hypertension 1987;9(suppl III):III193-III197.
20. Lüscher TF, Vanhoutte PM: The Endothelium Modulator of Cardiovascular Function. Boca Raton, Florida, CRC Press, 1990, pp 1-215.
21. Lüscher TF: Imbalance of endothelium-derived relaxing and contracting factors: a new concept in hypertension? Am J Hypertens 1990;3:317-330.
22. Gabbiani G, Elemer G, Guelpa C, et al: Morphologic and functional changes of the aortic intima during experimental hypertension. Am J Pathol 1979;96:399-414.
23. Limas C, Westrum B, Iwai J, Limas CJ: Aortic morphology in salt-dependent genetic hypertension. Am J Physiol 1982;107:378-394.
24. Palmer RMJ, Ashton DS, Moncado S: Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 1988;333:664.
25. Lüscher TF: Heterogeneity of endothelial dysfunction in hypertension. Eur Heart J 1992;13(suppl D):50-55.
26. Dohi Y, Thiel MA, Buhler FR, Lüscher TF: Activation of endothelial L-arginine pathway in resistance arteries: effect of age and hypertension. Hypertension 1990; 15:170-179.
27. Diederich D, Yang Z, Buhler FR, Lüscher TF: Impaired endothelium-dependent relaxations in hypertensive resistance arteries involve the cyclooxygenase pathway. Am J Physiol 1990;258:H445-H451.
28. Dohi Y, Criscione L, Lüscher TF: Renovascular hypertension impairs formation of endothelium-derived relaxing factors and sensitivity to endothelin-1 in resistance arteries. Br J Pharmacol 1991;104:349-354.
29. Lüscher TF, Vanhoutte PM: Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat. Hypertension 1986;8:344-348.
30. Lüscher TF, Boulanger CH, Dohi Y, Yang Z: Endothelium-derived contracting factors. Hypertension 1992; 19:117-130.
31. Kung CF, Lüscher TF: Different mechanisms of endothelial dysfunction with aging and hypertension in the rat aorta. Hypertension 1995;25:194-200.
32. DeFronzo RA, Cooke C, Andres G, et al: The effect of insulin on renal handling of sodium, potassium, calcium and phosphate in man. J Clin Invest 1975;55:845-855.
33. +2 concentration in isolated rat adipocytes. Diabetes 1987;36:174-178.
34. Pfeifle B, Ditschuneit H: Effects of insulin on growth of cultured human arterial smooth muscle cells. Diabetologia 1981;20:155-158.
35. Young JB: Effect of experimental hyperinsulinemia on sympathetic nervous system activity in the rat. Life Sci 1988;43:193-200.
36. Frank HJ, Levin ER, Hu RM, Pedram A: Insulin stimulates endothelin binding and action on cultured vascular smooth muscle cells. Endocrinology 1992;133:1092-1097.
37. Hu RM, Levin ER, Pedram A, Frank HJ: Insulin stimulates production and secretion of endothelin from bovine endothelial cells. Diabetes 1993;42:351-358.
38. Wolpert HA, Steen SN, Istfan NW, Simonson DC: Insulin modulates circulating endothelin-1 levels in humans. Metabolism 1993;42:1027-1030.
39. Takeda Y, Miyamori I, Yoneda T, Takeda R: Production of endothelin-1 from mesenteric arteries of streptozotocin-induced diabetic rats. Life Sci 1991;48:2253-2256.
40. Takahashi K, Gathei MA, Lam HC, et al: Elevated plasma endothelin in patients with diabetes mellitus. Diabetologia 1990;330:306-310.
41. Verma S, Bhanot S, McNeill JH: Effects of chronic endothelin blockade in an insulin resistant and hyperinsulinemic rodent model of hypertension. Am J Physiol 1995;269:H2017-H2021.
42. Scherrer U, Randin D, Vollenweider P, Vollenweider L, Nicod P: Nitric oxide release accounts for insulin's vascular effects in humans. J Clin Invest 1994;94:2511-2515.
43. Laakso M, Edelman SV, Brechtel G, Baron AD: Impaired insulin mediated skeletal muscle blood flow in patients with NIDDM. Diabetes 1992;41:1076-1083.
44. Wu H, Jeng YY, Yue C, et al: Endothelial-dependent vascular effects of insulin and insulin-like growth factor I in the perfused rat mesenteric artery and aortic ring. Diabetes 1994;43:1027-1032.