Comparative evaluation of SFE and solvent extraction methods on the yield and composition of black seeds (Nigella Sativa)

Journal of Liquid Chromatography and Related Technologies

Volumn 30, Issue 17, 2007, Pages 2545-2555

  Rao, Madduri V ^a   Al Marzouqi, Ali H ^a   Kaneez, Fatima S ^a   Ashraf, S Salman ^a   Adem, Abdu ^a  

^a UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

Antioxidant; Black seeds; HPLC characterization; Nigella sativa; SFE

Indexed keywords

CONCENTRATION (PROCESS); DRUG PRODUCTS; ESSENTIAL OILS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPIDS;

BLACK SEEDS; GSH RECOVERY TESTS; NIGELLA SATIVA; SUPERCRITICAL FLUID EXTRACTION (SFE);

SOLVENT EXTRACTION;

ANTIOXIDANT; CARBON DIOXIDE; NIGELLA SATIVA EXTRACT;

ANTIOXIDANT ACTIVITY; ARTICLE; BLACK CUMIN; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; SOLVENT EXTRACTION; SUPERCRITICAL FLUID EXTRACTION; TEMPERATURE SENSITIVITY;

NIGELLA SATIVA;

EID: 34547871669     PISSN: 10826076     EISSN: 1520572X     Source Type: Journal    
DOI: 10.1080/10826070701540100     Document Type: Article

References (25)

1. Ali, B.H.; Blunden, G. Pharmacological and toxicological properties of Nigella sativa. Phytother. Res. 2003, 17, 299-305.
2. Dragland, S.; Senoo, H.; Wake, K.; Holte, K.; Blomhoff, R. Several culinary and medicinal herbs are important sources of dietary antioxidants. J. Nutr. 2003, 133, 1286-1290.
3. Cheikh-Rouhou, S.; Besbes, S.; Hentati, B.; Blecker, C.; Eroanne, C.; Attia, H. Nigella sativa L: Chemical composition and physicochemical characteristics of lipid fraction. Food Chem. 2007, 101, 673-781.
4. Atta, M.B. Some characteristics of Nigella seed cultivated in Egypt and its lipid profile. Food Chem. 2003, 83, 63-68.
5. Nickavar, B.; Mojab, F.; Javidnia, K.; Amoli, M.A. Chemical composition of fixed and volatile oils of Nigella sativa L. from Iran. Z. Naturforsch 2003, 58, 629-31.
6. Ramadan, M.F.; Morsel, J.T. Analysis of glycolipids from black cumin (Nigella sativa L.) and Niger (Guizotia abyssinica Cass.) oil seeds. Food Chem. 2003, 80, 197-204.
7. D'Antuono, L.F.; Moretti, A.; Lovato, A.F.S. Seed yield, yield components, oil content and essential oil content and composition of Nigella sativa L. and Nigella damascene L. Ind. Crops Prod. 2002, 15, 59-69.
8. Muthu Kumara, S.S.; Huat, B.T.K. Extraction, isolation and characterization of antitumor principle a-Hederin, from the seeds of Nigella sativa. Planta Med. 2001, 67, 29-32.
9. Shah, S.; Ray, K.S. Study on antioxidant and antimicrobial properties of Black cumin (Nigella sativa Linn). J. Food Sci. & Technol. 2003, 40, 70-73.
10. Burits, M.; Bucar, F. Antioxidant activity of Nigella sativa essential oil. Phytother. Res. 2003, 14, 23-328.
11. Mahmoud, M.R.; El-Abhar, H.S.; Saleh, S. The effect of Nigella sativa oil against the liver damage induced by Schistosoma mansoni infection in mice. J. Ethnopharmacol. 2000, 79, 1-11.
12. Turkdogan, M.K.; Agaoglu, Z.; Yener, Z.; Sekeroglu, R.; Akkan, H.A.; Avci, M.E. The role of antioxidant vitamins (C and E), selenium and Nigella sativa in the prevention of liver fibrosis and cirrhosis in rabbits, new hopes. Dtscch. Tierarzt. Wschr. 2000, 108, 71-73.
13. Al-Marzouqi, A.H.; Rao, M.V.; Jobe, B. A comparative evaluation of SFE and steam distillation methods on the yield and composition of essential oil extracted from Spearmint (Mentha spicata). J. Liq. Chromatogr. & Rel. Technol. 2007, 30, 463-475.
14. Fullana, M.; Trabelsi, F.; Recasens, F. Use of neural net computing for statistical and kinetic modeling and simulation of supercritical fluid extractors. Chem. Eng. Sci. 2000, 55, 79-95.
15. Bruhl, L.; Matthaus, B. Extraction of oilseeds by SFE - a comparison with other methods for the determination of the oil content. Fresenius'. J. Anal. Chem. 1999, 364, 631-634.
16. 2: experiments and modelling. Chem. Eng. Sci. 1998, 53, 3711-3718.
17. Turkay, S.; Burford, M.D.; Sangun, M.K.; Ekinci, E.; Bartle, K.D.; Clifford, A.A. Deacidification of black seed oil extracted by supercritical carbon dioxide. J. Amer. Oil Chem. Soc. 1996, 3, 1265.
18. Ghosheh, O.A.; Houdi, A.A.; Crooks, P.A. High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed (Nigella sativa L.). J. Pharm. Biomed. Anal. 1999, 19, 757-762.
19. Atta-ur-Rahman; Malik, S.; Hasan, S.S.; Choudhary, M.I.; Ni, C.Z.; Clardy, J. Nigellidine- A new alkaloid from the seeds of Nigella sativa. J. Tetrahed. Lett. 1995, 36, 1993-1996.
20. Houghton, P.J.; Zarka, R.; de las Heras, B.; Hoult, J.R. Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation. Planta Med. 1995, 61, 33-36.
21. Rao, N.R.; Snyder, R. Oxidative modifications produced in HL-60 cells on exposure to benzene metabolites. J. Appl. Toxicol. 1995, 15, 403-409.
22. Edelfors, S.; Hass, U.; Hougaard, K.S. Changes in markers of oxidative stress and membrane properties in synaptosomes from rats exposed prenatally to toluene. Pharmacol. Toxicol. 2002, 90, 26-31.
23. Sies, H. Oxidative stress: oxidants and antioxidants. Exp. Physiol. 1997, 82, 291-295.
24. Ashraf, S.S.; Galadari, S.; Patel, M. Protein S-thiolation and depletion of intracellular glutathione in Skin Fibroblasts exposed to various sources of oxidative stress. Environ. Toxicol. Pharmacol. 2006, 22, 75-79.
25. Coleman, C.A.; Hull, B.E.; McDougal, J.N.; Rogers, J.V. The effect of m-xylene on cytotoxicity and cellular antioxidant status in rat dermal equivalents. Toxicol. Lett. 2003, 142, 133.