The role of antioxidant vitamins (C and E), selenium and nigella sativa in the prevention of liver fibrosis and cirrhosis in rabbits: New hopes

Deutsche Tierarztliche Wochenschrift

Volumn 108, Issue 2, 2001, Pages 71-73

  Turkdogan M K ^a   Agaoglu Z ^a   Yener, Z ^a   Sekeroglu R ^a   Akkan, H A ^a   Avci, M E ^a  

^a YUZUNCU YIL UNIVERSITY   (Turkey)

Author keywords

Cirrhosis; Liver fibrosis; Nigella sativa; Selenium; Vitamin C; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; SELENIUM;

ANIMAL; ANIMAL DISEASE; ARTICLE; CHEMICALLY INDUCED DISORDER; EXPERIMENTAL LIVER CIRRHOSIS; MEDICINAL PLANT; PHYSIOLOGY; PHYTOTHERAPY; PLANT SEED; RABBIT;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; LIVER CIRRHOSIS, EXPERIMENTAL; PHYTOTHERAPY; PLANTS, MEDICINAL; RABBITS; SEEDS; SELENIUM; VITAMIN E;

EID: 0035259357     PISSN: 03416593     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. BERAUD, C. (1979): Cirrhoses. In: Péquignot, H., ed. Pathologie Médicale. Second ed. Paris: Masson, pp: 1226-1241.
2. BRITTON, R. S., BACON, B. R. (1994): Role of free radicals in liver diseases and hepatic fibrosis. Hepatogastroenterology. 41, 343-348.
3. CAMPS, J., BARGALLO, T. A., GIMENEZ, A. S., CABALLERIA PARES, J. A., JOVEN, J. (1992): Lipid peroxidation and fibrogenesis in carbon tetrachloride treated rats: effect of zinc administration. Bull. Soc. Ophtalmol. Fr., 83, 695-700.
4. CASINI, A., CENI, E., SALZANO, R., BIONDI, P., PAROLA, M., GALLI, A., FOSCHI, M. (1997): Neutrophil-derived superoxide anion induces lipid peroxidation and stimulates collagen synthesis in human hepatic stellate cells: role of nitric oxide. Hepatology. 25, 361-367.
5. ELKADI, A., KANDIL, O. (1997): The black seed (Nigella sativa) as a natural immune enhancer (Abstract.) First international conference on scientific miracles of Quran and Sunnah. Islamabad, Pakistan.
6. GIMENEZ, A., PARES, A., ALIE, S., CAMPS, J., DEULAFEU, R., CABALLERIA, J., RODES, J. (1994): Fibrogenetic and collagenolytic activity in CCl4 injured rats: beneficial effects of zinc administration. J. Hepatol., 21, 292-298.
7. HANAFY, M. S., HATEM, M. E. (1991): Studies on the antimicrobial activity of Nigella Sativa seed (black cumin). J. Indian State Med. Assoc. 34, 275-278.
8. HOUGHTON, P.J., ZARKA, R., HERAS, B., HOULT, J. R. S. (1995): Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation. Planta Med. 61, 33-36.
9. KAHL, R. (1991): Toxic liver injury. In: N. McINTYRE, J.-P. BENHAMOU, J. BIRCHER, M. RIZZETTO and J. RODES, (eds). Oxford textbook of Clinical Hepatology. Volume 2. pp. 905-918. New York. Oxford university press.
10. th Ed., pp. 239-340. Academic press, London.
11. LI, R., BROWN, K. E., SOWEID, A. M., BRITTON, R. S., POULOS, J. E., BACON, B. R. (1995): Vitamin E suppresses lipocyte activation in chronic iron over-load (abstract). Hepatology, 22, 279A.
12. MAHFOUZ, M, EL-DAKHAKHNY, M., GEMED, A., MOUSSA, H. (1962): Choleretic action of Nigella Sativa seeds oil. Pharm. Bull., 44, 225-227.
13. MAHFOUZ, M., EL-DAKHAKHNY, M. (1960): Some chemical and pharmacological properties of the new antiasthmatic drug "Nigellone". Pharm. Bull. 42, 411-415.
14. MÉZES, M., VIRAG, GY., BARTA, M., ABOUZEID, A. D. (1996): Effect of lipid peroxide loading on lipid peroxidation and on the glutathione and cytochrome systems in rabbits. Acta Vet. Hung., 44, 443-450.
15. th ed. pp. 337-403. London. Blackwell Science.