Preparation and biological evaluation of 2-amino-6-[18F]fluoro-9-(4-hydroxy-3-hydroxy-methylbutyl) purine (6-[18F]FPCV) as a novel PET probe for imaging HSV1-tk reporter gene expression

Nuclear Medicine and Biology

Volumn 34, Issue 6, 2007, Pages 717-725

  Cai, Hancheng ^a,e   Yin, Duanzhi ^a   Zhang, Lan ^a,d   Yang, Xiaofeng ^b   Xu, Xiaoyan ^b   Liu, Weiguo ^b   Zheng, Xuesheng ^b   Zhang, Hong ^c   Wang, Jing ^c,d   Xu, Yuhong ^d   Cheng, Dengfeng ^a   Zheng, Mingqiang ^a   Han, Yanjiang ^a   Wu, Mingxing ^a   Wang, Yongxian ^a  

^a SHANGHAI INSTITUTE OF APPLIED PHYSICS   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c ZHEJIANG UNIVERSITY   (China)

^d Zhejiang California International NanoSystems Institute   (China)

^e UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

6 18F FPCV; Gene expression; HSV1 tk; PET

Indexed keywords

2 AMINO 6 FLUORO 9 (4 HYDROXY 3 HYDROXYMETHYLBUTYL)PURINE F 18; BOVINE SERUM ALBUMIN; RADIOPHARMACEUTICAL AGENT; THYMIDINE KINASE 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG UPTAKE; FLUORINATION; GENE EXPRESSION; HERPES SIMPLEX VIRUS 1; IN VITRO STUDY; IN VIVO STUDY; INOCULATION; MOLECULAR PROBE; NONHUMAN; NUDE MOUSE; POSITRON EMISSION TOMOGRAPHY; RAT; REPORTER GENE; WILD TYPE;

ANIMALS; BLOTTING, WESTERN; BUFFERS; CELL LINE, TUMOR; GENES, REPORTER; HALF-LIFE; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; IMMUNOHISTOCHEMISTRY; ISOTOPE LABELING; MICE; MICE, INBRED BALB C; MICE, NUDE; PHOSPHATES; POSITRON-EMISSION TOMOGRAPHY; PURINES; QUALITY CONTROL; RADIOPHARMACEUTICALS; SERUM ALBUMIN, BOVINE; SODIUM CHLORIDE; THYMIDINE KINASE; TISSUE DISTRIBUTION;

EID: 34547870547     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2007.06.005     Document Type: Article

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