-
1
-
-
11844251380
-
Bone health and osteoporosis
-
Office of the Surgeon General, USA: U.S. Dept of Health and Human Services;, Report No 1
-
Office of the Surgeon General. Bone health and osteoporosis: A report of the Surgeon General. USA: U.S. Dept of Health and Human Services; 2004. Report No 1.
-
(2004)
A report of the Surgeon General
-
-
-
3
-
-
0037129560
-
Epidemiology and outcomes of osteoporotic fractures
-
Cummings SR, Melton LJ. Epidemiology and outcomes of osteoporotic fractures. Lancet 2002; 359:1761-1767.
-
(2002)
Lancet
, vol.359
, pp. 1761-1767
-
-
Cummings, S.R.1
Melton, L.J.2
-
4
-
-
0028799124
-
The worldwide problem of osteoporosis: Insights afforded by epidemiology
-
Riggs BL, Melton LJ III. The worldwide problem of osteoporosis: insights afforded by epidemiology. Bone 1995; 17(Suppl.5):505S-511S.
-
(1995)
Bone
, vol.17
, Issue.SUPPL.5
-
-
Riggs, B.L.1
Melton III, L.J.2
-
5
-
-
23044491391
-
Genetic determinants of osteoporosis
-
Ralston SH. Genetic determinants of osteoporosis. Curr Opin Rheumatol 2005; 17:475-479.
-
(2005)
Curr Opin Rheumatol
, vol.17
, pp. 475-479
-
-
Ralston, S.H.1
-
6
-
-
2642572830
-
Genetic research in osteoporosis: Where are we? Where should we go next?
-
Recker RR. Genetic research in osteoporosis: Where are we? Where should we go next? J Musculoskelet Neuronal Interact 2004; 4:86-90.
-
(2004)
J Musculoskelet Neuronal Interact
, vol.4
, pp. 86-90
-
-
Recker, R.R.1
-
7
-
-
0031469444
-
Genetic and environmental components of the population variance in bone density
-
Seeman E, Hopper JL. Genetic and environmental components of the population variance in bone density. Osteoporos Int 1997; 7(Suppl.3):S10-16.
-
(1997)
Osteoporos Int
, vol.7
, Issue.SUPPL.3
-
-
Seeman, E.1
Hopper, J.L.2
-
8
-
-
0347407798
-
Molecular and genetic mechanisms of osteoporosis: Implication for treatment
-
Shen H, Reeker RR, Deng HW. Molecular and genetic mechanisms of osteoporosis: Implication for treatment. Curr Mol Med 2003; 3:737-757.
-
(2003)
Curr Mol Med
, vol.3
, pp. 737-757
-
-
Shen, H.1
Reeker, R.R.2
Deng, H.W.3
-
9
-
-
0033048225
-
Recent progress in understanding the genetic susceptibility to osteoporosis
-
Zmuda JM, Cauley JA, Ferrell RE. Recent progress in understanding the genetic susceptibility to osteoporosis. Genet Epidemiol 1999; 16:356-367.
-
(1999)
Genet Epidemiol
, vol.16
, pp. 356-367
-
-
Zmuda, J.M.1
Cauley, J.A.2
Ferrell, R.E.3
-
10
-
-
33747674263
-
The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment
-
Sawakami K, Robling AG, Ai M, Pitner ND, Liu D, Warden SJ, Li J, Mave P, Rowe DW, Duncan RL, Warman ML, Turner CH. The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment. J Biol Chem 2006; 281:23698-23711
-
(2006)
J Biol Chem
, vol.281
, pp. 23698-23711
-
-
Sawakami, K.1
Robling, A.G.2
Ai, M.3
Pitner, N.D.4
Liu, D.5
Warden, S.J.6
Li, J.7
Mave, P.8
Rowe, D.W.9
Duncan, R.L.10
Warman, M.L.11
Turner, C.H.12
-
11
-
-
33846026749
-
Wnt/b-catenin signaling is a normal physiological response to mechanical loading in bone
-
Robinson JA, Chatterjee-Kishore M, Yaworsky PJ, Cullen DM, Zhao W, Li C, Kharode Y, Sauter L, Babi JP, Brown EL, Hill AA, Akhter MP, Johnson ML, Recker RR, Komm BS, Bex FJ. Wnt/b-catenin signaling is a normal physiological response to mechanical loading in bone. J Biol Chem 2006; 281:31720-31728.
-
(2006)
J Biol Chem
, vol.281
, pp. 31720-31728
-
-
Robinson, J.A.1
Chatterjee-Kishore, M.2
Yaworsky, P.J.3
Cullen, D.M.4
Zhao, W.5
Li, C.6
Kharode, Y.7
Sauter, L.8
Babi, J.P.9
Brown, E.L.10
Hill, A.A.11
Akhter, M.P.12
Johnson, M.L.13
Recker, R.R.14
Komm, B.S.15
Bex, F.J.16
-
12
-
-
0036138175
-
A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait
-
Little RD, Carulli JP, Del Mastro RG, Dupuis J, Osborne M, Folz C, et al. A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait. Am J Hum Genet 2002; 70:11-19.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 11-19
-
-
Little, R.D.1
Carulli, J.P.2
Del Mastro, R.G.3
Dupuis, J.4
Osborne, M.5
Folz, C.6
-
13
-
-
0037118279
-
Regulation of bone formation and vision by LRP5
-
Patel MS, Karsenty G. Regulation of bone formation and vision by LRP5. N Engl J Med 2002; 346:1572-1574.
-
(2002)
N Engl J Med
, vol.346
, pp. 1572-1574
-
-
Patel, M.S.1
Karsenty, G.2
-
14
-
-
12144287023
-
LRP5, low-density-lipoprotein-receptor-related protein 5, is a determinant for bone mineral density
-
Mizuguchi T, Furuta I, Watanabe Y, Tsukamoto K, Tomita H, Tsujihata M, Ohta T, Kishino T, Matsumoto N, Minakami H, Niikawa N, Yoshiura K. LRP5, low-density-lipoprotein-receptor-related protein 5, is a determinant for bone mineral density. J Hum Genet 2004; 49:80-86.
-
(2004)
J Hum Genet
, vol.49
, pp. 80-86
-
-
Mizuguchi, T.1
Furuta, I.2
Watanabe, Y.3
Tsukamoto, K.4
Tomita, H.5
Tsujihata, M.6
Ohta, T.7
Kishino, T.8
Matsumoto, N.9
Minakami, H.10
Niikawa, N.11
Yoshiura, K.12
-
16
-
-
2442656675
-
The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with mesd
-
Zhang Y, Wang Y, Li X, Zhang J, Mao J, Li Z, Zheng J, Li L, Harris S, Wu D. The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with mesd. Mol Cell Biol 2004; 24:4677-4684.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4677-4684
-
-
Zhang, Y.1
Wang, Y.2
Li, X.3
Zhang, J.4
Mao, J.5
Li, Z.6
Zheng, J.7
Li, L.8
Harris, S.9
Wu, D.10
-
17
-
-
27144458524
-
Wnt signalling pathway: A new target for the treatment of osteoporosis
-
Rawadi G, Roman Roman S. Wnt signalling pathway: a new target for the treatment of osteoporosis. Expert Opin Ther Targets 2005; 9:1063-1077.
-
(2005)
Expert Opin Ther Targets
, vol.9
, pp. 1063-1077
-
-
Rawadi, G.1
Roman Roman, S.2
-
18
-
-
2342529785
-
Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with variation in vertebral bone mass, vertebral bone size, and stature in whites
-
Ferrari SL, Deutsch S, Choudhury U, Chevalley T, Bonjour JP, Dermitzakis ET, Rizzoli R, Antonarakis SE. Polymorphisms in the low-density lipoprotein receptor-related protein 5 (LRP5) gene are associated with variation in vertebral bone mass, vertebral bone size, and stature in whites. Am J Hum Genet 2004; 74:866-875.
-
(2004)
Am J Hum Genet
, vol.74
, pp. 866-875
-
-
Ferrari, S.L.1
Deutsch, S.2
Choudhury, U.3
Chevalley, T.4
Bonjour, J.P.5
Dermitzakis, E.T.6
Rizzoli, R.7
Antonarakis, S.E.8
-
19
-
-
3042732142
-
The high bone mass family - the role of Wnt/Lrp5 signaling in the regulation of bone mass
-
Johnson ML. The high bone mass family - the role of Wnt/Lrp5 signaling in the regulation of bone mass. J Musculoskelet Neuronal Interact 2004; 4:135-138.
-
(2004)
J Musculoskelet Neuronal Interact
, vol.4
, pp. 135-138
-
-
Johnson, M.L.1
-
20
-
-
18044394808
-
LRP5 gene polymorphisms predict bone mass and incident fractures in elderly Australian women
-
Bollerslev J, Wilson SO, Dick IM, Islam FM, Ueland T, Palmer L, Devine A, Prince RL. LRP5 gene polymorphisms predict bone mass and incident fractures in elderly Australian women. Bone 2005; 36:599-606.
-
(2005)
Bone
, vol.36
, pp. 599-606
-
-
Bollerslev, J.1
Wilson, S.O.2
Dick, I.M.3
Islam, F.M.4
Ueland, T.5
Palmer, L.6
Devine, A.7
Prince, R.L.8
-
21
-
-
14844326069
-
Contribution of the LRP5 gene to normal variation in peak BMD in women
-
Koller DL, Ichikawa S, Johnson ML, Lai D, Xuei X, Edenberg HJ, Conneally PM, Hui SL, Johnston CC, Peacock M, Foroud T, Econs MJ. Contribution of the LRP5 gene to normal variation in peak BMD in women. J Bone Miner Res 2005; 20:75-80.
-
(2005)
J Bone Miner Res
, vol.20
, pp. 75-80
-
-
Koller, D.L.1
Ichikawa, S.2
Johnson, M.L.3
Lai, D.4
Xuei, X.5
Edenberg, H.J.6
Conneally, P.M.7
Hui, S.L.8
Johnston, C.C.9
Peacock, M.10
Foroud, T.11
Econs, M.J.12
-
22
-
-
10744224854
-
High bone mass in mice expressing a mutant LRP5 gene
-
Babij P, Zhao W, Small C, Kharode Y, Yaworsky PJ, Bouxsein ML, Reddy PS, Bodine PV, Robinson JA, Bhat B, Marzolf J, Moran RA, Bex F. High bone mass in mice expressing a mutant LRP5 gene. J Bone Miner Res 2003; 18:960-974.
-
(2003)
J Bone Miner Res
, vol.18
, pp. 960-974
-
-
Babij, P.1
Zhao, W.2
Small, C.3
Kharode, Y.4
Yaworsky, P.J.5
Bouxsein, M.L.6
Reddy, P.S.7
Bodine, P.V.8
Robinson, J.A.9
Bhat, B.10
Marzolf, J.11
Moran, R.A.12
Bex, F.13
-
23
-
-
2942722529
-
Bone biomechanical properties in LRP5 mutant mice
-
Akhter MP, Wells DJ, Short SJ, Cullen DM, Johnson ML, Haynatzki GR, Babij P, Allen KM, Yaworsky PJ, Bex F, Recker RR. Bone biomechanical properties in LRP5 mutant mice. Bone 2004; 35:162-169.
-
(2004)
Bone
, vol.35
, pp. 162-169
-
-
Akhter, M.P.1
Wells, D.J.2
Short, S.J.3
Cullen, D.M.4
Johnson, M.L.5
Haynatzki, G.R.6
Babij, P.7
Allen, K.M.8
Yaworsky, P.J.9
Bex, F.10
Recker, R.R.11
-
24
-
-
0037373341
-
Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density
-
Van Wesenbeeck L, Cleiren E, Gram J, Beals RK, Benichou O, Scopelliti D, Key L, Renton T, Bartels C, Gong Y, Warman ML, De Vernejoul MC, Bollerslev J, Van Hul W. Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density. Am J Hum Genet 2003; 72:763-771.
-
(2003)
Am J Hum Genet
, vol.72
, pp. 763-771
-
-
Van Wesenbeeck, L.1
Cleiren, E.2
Gram, J.3
Beals, R.K.4
Benichou, O.5
Scopelliti, D.6
Key, L.7
Renton, T.8
Bartels, C.9
Gong, Y.10
Warman, M.L.11
De Vernejoul, M.C.12
Bollerslev, J.13
Van Hul, W.14
-
25
-
-
0037092049
-
Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt co-receptor
-
Kato M, Patel MS, Levasseur R, Lobov I, Chang BH, Glass DA, 2nd, Hartmann C, Li L, Hwang TH, Brayton CF, Lang RA, Karsenty G, Chan L. Cbfa1-independent decrease in osteoblast proliferation, osteopenia, and persistent embryonic eye vascularization in mice deficient in Lrp5, a Wnt co-receptor. J Cell Biol 2002; 157:303-314.
-
(2002)
J Cell Biol
, vol.157
, pp. 303-314
-
-
Kato, M.1
Patel, M.S.2
Levasseur, R.3
Lobov, I.4
Chang, B.H.5
Glass 2nd, D.A.6
Hartmann, C.7
Li, L.8
Hwang, T.H.9
Brayton, C.F.10
Lang, R.A.11
Karsenty, G.12
Chan, L.13
-
26
-
-
5044228112
-
Wnt signaling in osteoblasts and bone diseases
-
Westendorf JJ, Kahler RA, Schroeder TM. Wnt signaling in osteoblasts and bone diseases. Gene 2004; 341:19-39.
-
(2004)
Gene
, vol.341
, pp. 19-39
-
-
Westendorf, J.J.1
Kahler, R.A.2
Schroeder, T.M.3
-
27
-
-
28444438846
-
LRP5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice
-
Clement Lacroix P, Ai M, Morvan F, Roman Roman S, Vayssiere B, Belleville C, Estrera K, Warman ML, Baron R, Rawadi G. LRP5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice. Proc Natl Acad Sci USA 2005; 102:17406-17411.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17406-17411
-
-
Clement Lacroix, P.1
Ai, M.2
Morvan, F.3
Roman Roman, S.4
Vayssiere, B.5
Belleville, C.6
Estrera, K.7
Warman, M.L.8
Baron, R.9
Rawadi, G.10
-
28
-
-
20244373613
-
Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation
-
Glass DA II, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G. Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell 2005; 8:751-764.
-
(2005)
Dev Cell
, vol.8
, pp. 751-764
-
-
Glass II, D.A.1
Bialek, P.2
Ahn, J.D.3
Starbuck, M.4
Patel, M.S.5
Clevers, H.6
Taketo, M.M.7
Long, F.8
McMahon, A.P.9
Lang, R.A.10
Karsenty, G.11
-
29
-
-
0034082288
-
Genetic regulation of cortical and trabecular bone strength and microstructure in inbred strains of mice
-
Turner CH, Hsieh YF, Muller R, Bouxsein ML, Baylink DJ, Rosen CJ, Grynpas MD, Donahue LR, Beamer WG. Genetic regulation of cortical and trabecular bone strength and microstructure in inbred strains of mice. J Bone Miner Res 2000; 15:1126-1131.
-
(2000)
J Bone Miner Res
, vol.15
, pp. 1126-1131
-
-
Turner, C.H.1
Hsieh, Y.F.2
Muller, R.3
Bouxsein, M.L.4
Baylink, D.J.5
Rosen, C.J.6
Grynpas, M.D.7
Donahue, L.R.8
Beamer, W.G.9
-
30
-
-
0029880186
-
Genetic variability in adult bone density among inbred strains of mice
-
Beamer WG, Donahue LR, Rosen CJ, Baylink DJ. Genetic variability in adult bone density among inbred strains of mice. Bone 1996; 18:397-403.
-
(1996)
Bone
, vol.18
, pp. 397-403
-
-
Beamer, W.G.1
Donahue, L.R.2
Rosen, C.J.3
Baylink, D.J.4
-
32
-
-
33747649856
-
Ulna loading response altered by the HBM mutation
-
Cullen DM, Akhter MP, Johnson ML, Morgan S, Recker RR. Ulna loading response altered by the HBM mutation. J Bone Miner Res 2004; 19(Suppl.1):S396.
-
(2004)
J Bone Miner Res
, vol.19
, Issue.SUPPL.1
-
-
Cullen, D.M.1
Akhter, M.P.2
Johnson, M.L.3
Morgan, S.4
Recker, R.R.5
-
33
-
-
23844490526
-
Application of micro-CT assessment of 3-D bone microstructure in preclinical and clinical studies
-
Jiang Y, Zhao J, Liao EY, Dai RC, Wu XP, Genant HK. Application of micro-CT assessment of 3-D bone microstructure in preclinical and clinical studies. J Bone Miner Metab 2005; 23(Suppl.):122-131.
-
(2005)
J Bone Miner Metab
, vol.23
, Issue.SUPPL.
, pp. 122-131
-
-
Jiang, Y.1
Zhao, J.2
Liao, E.Y.3
Dai, R.C.4
Wu, X.P.5
Genant, H.K.6
-
34
-
-
0033805547
-
Genetic variations in bone density, histomorphometry, and strength in mice
-
Akhter MP, Iwaniec UT, Covey MA, Cullen DM, Kimmel DB, Recker RR. Genetic variations in bone density, histomorphometry, and strength in mice. Calcif Tissue Int 2000; 67:337-344.
-
(2000)
Calcif Tissue Int
, vol.67
, pp. 337-344
-
-
Akhter, M.P.1
Iwaniec, U.T.2
Covey, M.A.3
Cullen, D.M.4
Kimmel, D.B.5
Recker, R.R.6
-
35
-
-
0031252252
-
Effects of multiple freezing-thawing cycles on ultimate indentation load and stiffness of bovine cancellous bone
-
Kang Q, An YH, Friedman RJ. Effects of multiple freezing-thawing cycles on ultimate indentation load and stiffness of bovine cancellous bone. Am J Vet Res 1997; 58:1171-1173.
-
(1997)
Am J Vet Res
, vol.58
, pp. 1171-1173
-
-
Kang, Q.1
An, Y.H.2
Friedman, R.J.3
-
36
-
-
3042713633
-
The human LRP5 G171V mutation in mice alters the skeletal response to limb unloading but not to ovariectomy
-
Bex F, Green J, Marzolf J, Babij P, Yaworsky PJ, Kharode Y. The human LRP5 G171V mutation in mice alters the skeletal response to limb unloading but not to ovariectomy. J Bone Miner Res 2003; 18(Suppl.1):S60.
-
(2003)
J Bone Miner Res
, vol.18
, Issue.SUPPL.1
-
-
Bex, F.1
Green, J.2
Marzolf, J.3
Babij, P.4
Yaworsky, P.J.5
Kharode, Y.6
-
37
-
-
0037163113
-
Regulation of Wnt signaling during adipogenesis
-
Bennett CN, Ross SE, Longo KA, Bajnok L, Hemati N, Johnson KW, Harrison SD, MacDougald OA. Regulation of Wnt signaling during adipogenesis. J Biol Chem 2002; 277:30998-31004.
-
(2002)
J Biol Chem
, vol.277
, pp. 30998-31004
-
-
Bennett, C.N.1
Ross, S.E.2
Longo, K.A.3
Bajnok, L.4
Hemati, N.5
Johnson, K.W.6
Harrison, S.D.7
MacDougald, O.A.8
-
38
-
-
4644326231
-
Wnt/beta-catenin and estrogen signaling converge in vivo
-
Kouzmenko AP, Takeyama K, Ito S, Furutani T, Sawatsubashi S, Maki A, Suzuki E, Kawasaki Y, Akiyama T, Tabata T, Kato S. Wnt/beta-catenin and estrogen signaling converge in vivo. J Biol Chem 2004; 279:40255-40258.
-
(2004)
J Biol Chem
, vol.279
, pp. 40255-40258
-
-
Kouzmenko, A.P.1
Takeyama, K.2
Ito, S.3
Furutani, T.4
Sawatsubashi, S.5
Maki, A.6
Suzuki, E.7
Kawasaki, Y.8
Akiyama, T.9
Tabata, T.10
Kato, S.11
-
39
-
-
0037036393
-
Liganded androgen receptor interaction with beta-catenin: Nuclear co-localization and modulation of transcriptional activity in neuronal cells
-
Pawlowski JE, Ertel JR, Allen MP, Xu M, Butler C, Wilson EM, Wierman ME. Liganded androgen receptor interaction with beta-catenin: nuclear co-localization and modulation of transcriptional activity in neuronal cells. J Biol Chem 2002; 277:20702-20710.
-
(2002)
J Biol Chem
, vol.277
, pp. 20702-20710
-
-
Pawlowski, J.E.1
Ertel, J.R.2
Allen, M.P.3
Xu, M.4
Butler, C.5
Wilson, E.M.6
Wierman, M.E.7
-
40
-
-
0037192870
-
Linking beta-catenin to androgen-signaling pathway
-
Yang F, Li X, Sharma M, Sasaki CY, Longo DL, Lim B, Sun Z. Linking beta-catenin to androgen-signaling pathway. J Biol Chem 2002; 277:11336-11344.
-
(2002)
J Biol Chem
, vol.277
, pp. 11336-11344
-
-
Yang, F.1
Li, X.2
Sharma, M.3
Sasaki, C.Y.4
Longo, D.L.5
Lim, B.6
Sun, Z.7
-
41
-
-
11944265977
-
Bone intrinsic material properties in three inbred mouse strains
-
Akhter MP, Fan Z, Rho JY. Bone intrinsic material properties in three inbred mouse strains. Calcif Tissue Int 2004; 75:416-420.
-
(2004)
Calcif Tissue Int
, vol.75
, pp. 416-420
-
-
Akhter, M.P.1
Fan, Z.2
Rho, J.Y.3
|